Incorporating wearable sensor data into research workflows

Gregory B Sands, Hayden Randles, Poul M F Nielsen

Auckland Bioengineering Institute, University of Auckland, New Zealand

Modelling the neural regulation of gastric motility at the tissue level

Omkar N. Athavale, Recep Avci, Alys R. Clark, Leo K. Cheng, Peng Du

University of Auckland, New Zealand

Efficient numerical simulation of effective micro-macro models for reactive transport in elastic perforated media

Jonas Knoch¹, Nicolas Neuß¹, Markus Gahn², Maria Neuss-Radu^1,2

¹FAU Erlangen-Nürnberg, Germany; ²Universität Heidelberg, Germany

The development of the phantom fiber to mimick muscle fibre activity for the validation of magnetomyography sensors

Ahmet Dogukan Keles¹, Thomas Klotz^1,2, Justus Marquetand³, Oliver Röhrle^1,2

¹Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Stuttgart, Germany; ²Stuttgart Center for Simulation Sciences (SC SimTech), University of Stuttgart, Stuttgart, Germany; ³MEG-Center Tübingen, University of Tübingen, Tübingen, Germany

A multiscale network model of tumor microenvironment to predict immunotherapeutic response of head and neck cancers

Priyan Bhattacharya^1,4, Andrew South^2,4, My Mahoney^2,4, Adam Luginbuhl^3,4, Rajanikanth Vadigepalli^1,4

¹Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America; ²Department of Pharmacology, Physiology and Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America; ³Department of Otolaryngology - Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America; ⁴Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Mechanobiological modelling to capture relative effects of deviatoric and volumetric stresses on epiphyseal bone growth

Jorge Mateos Arriola¹, Carlos Ruiz Wills¹, Miguel A. González Ballester^1,2, Jérôme Noailly¹

¹Universitat Pompeu Fabra, Spain; ²ICREA, Spain

Sensory perturbation due to blood flow restriction leads to change in active MU pool

Franziska Bubeck^1,2, Mansour Taleshi³, Ivan Vujaklija³, Oliver Röhrle^1,2, Leonardo Gizzi⁴

¹Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Stuttgart, Germany; ²Stuttgart Center for Simulation Science, University of Stuttgart, Stuttgart, Germany; ³Department of Electrical Engineering and Automation, Aalto University, Espoo, Finland; ⁴Department of Biomechatronic Systems, Fraunhofer Institute for Manufacturing Engineering and Automation, Stuttgart, Germany

A graphic representation of arterial pulse pressure vs. mean arterial pressure time series may be used for clinical decision support during intraoperative hypotension

Estefanía Žugelj Tapia¹, Marko Žličar², Borut Kirn¹

¹University of Ljubljana, Medical faculty, Ljubljana, Slovenia; ²University Clinical Centre, Ljubljana, Slovenija

Development of a hemodynamic model to simulate heart failure patients

Juliana Franz^1,2, Arina Borzistaia^1,2, Titus Kühne^1,2, Leonid Goubergrits^1,2

¹Charité - Universitätsmedizin Berlin, Germany; ²Deutsches Herzzentrum der Charité, Institute of Computer-assisted Cardiovascular Medicine, Berlin, Germany

Hypertensive signature in the photoplethysmography signal by combining a whole-body cardiovascular model and optical simulations

Clement Vasseur, Xavier Bednarek, Pierre Blandin, Matthieu Perriolat, Guillaume Blanquer

Univ. Grenoble Alpes, CEA, LETI, DTIS, Grenoble, France

Pre-procedural planning of transcatheter heart valve interventions using imaging and in silico modelling

Shelly Singh-Gryzbon

University of Cambridge, United Kingdom

A 0D-1D global, closed-loop model of the cardiovascular system

Stefano Costa¹, Lucas Omar Mueller¹, Federica Caforio^2,3,4

¹Dipartimento di Matematica, Università di Trento, (Italy); ²Department of Mathematics and Scientific Computing, NAWI Graz, University of Graz (Austria); ³Gottfried Schatz Research Center: Division of Biophysics, Medical University of Graz (Austria); ⁴BioTechMed-Graz, (Austria)

In silico validation of TAG-based coronary blood flow distribution methods for patient-specific computational iFR prediction

Ester Bergantin, Lucas Omar Müller

University of Trento, Italy

A comparative study between 3D segmentation methods of aorta in contrast enhanced MR acquisitions

Horia Andrei Leonte^1,2, Alexandru Constantin Serban^1,2, Lucian Mihai Itu^1,2

¹Electrical Engineering and Computer Science, Transilvania University of Brasov, Romania; ²Advanta, Siemens SRL, Brasov, Romania

Simulation workflow for stent-assisted coiling of brain aneurysms

Felix Borges, Alexander Pugachev

Simq GmbH, Germany

Atmospheric pollutants and atrial arrhythmias: An in silico study

Catalina Tobon¹, Laura C Palacio¹, Sami F Noujaim², Javier Saiz³

¹MATBIOM, Universidad de Medellín, Medellín, Colombia; ²Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States; ³Centro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, Valencia, Spain

In-silico assessment of hemodynamics in stenoses of the fontan circulation

Adriano Schlief^1,2, Simon Bender^1,2, Peter Kramer^2,3, Marie Schafstedde^1,2,4, Jan Brüning^1,2,4

¹Institute of Computer-assisted Cardiovascular Medicine, Charité – Universitätsmedizin Berlin, Germany; ²Deutsches Herzzentrum der Charité, Berlin, Germany; ³Department of Pediatric Cardiology, Charité – Universitätsmedizin Berlin, Germany; ⁴DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany

A clinical decision support tool for patient management

Krzysztof Gądek, Adam Nowak, Rafał Niżankowski, Dominik Radziszowski, Joanna Twaróg, Maja Więckiewicz

Sano – Centre for Computational Personalised Medicine International Research Foundation, Poland

Creation and regression analysis of a hemodynamic virtual patient database

Richard Weber, Márta Viharos, Katalin Pálfalvi, Dániel Gyürki, György Paál

Department of Hydrodynamic Systems, Faculty of Mechanical Engineering, Budapest University of Technology and Economics Műegyetem rkp. 3., H-1111 Budapest, Hungary

Towards a prostate cancer radiotherapy digital twin: Simulating the response of prostate cancer to external radiotherapy through mechanistic multiscale modelling. Sensitivity analysis and clinical adaptation

Eleni Kolokotroni A.¹, Foteini Panagiotidou¹, Stamatia Tsampa¹, Christos Kyroudis¹, Simon Spohn^2,3,4, Anca-Ligia Grosu^2,3, Dimos Baltas^3,5, Ilias Sachpazidis^3,5, Constantinos Zamboglou^2,3,6, Georgios S. Stamatakos¹

¹National Technical University of Athens, School of Electrical and Computer Engineering, Institute of Communication and Computer Systems, In Silico Oncology and In Silico Medicine Group, Greece; ²University of Freiburg, Faculty of Medicine, University Medical Center Freiburg, Department of Radiation Oncology, Germany; ³German Cancer Consortium (DKTK). Partner Site Freiburg, Germany; ⁴Berta-Ottenstein-Programme, Faculty of Medicine, University of Freiburg, Freiburg, Germany; ⁵University of Freiburg, Faculty of Medicine, University Medical Center Freiburg, Department of Radiation Oncology, Division of Medical Physics, Germany; ⁶German Oncology Center, European University Cyprus, Limassol, Cyprus

Recommendations and requirements for implementing computational models in clinical integrated decision support systems (ISO/TS 9491-2)

Laura Lopez-Perez¹, Elena Martinelli², Marc Kirschner³, Sylvia Krobitsch³, Heike Moser⁴, Giuseppe Fico¹, Tito Poli², Martin Golebiewski⁵

¹Universidad Politécnica de Madrid-Life Supporting Technologies Research Group, ETSIT, 28040 Madrid, Spain; ²Unit of Maxillofacial Surgery, Department of Medicine and Surgery, University Hospital of Parma, Parma, Italy; ³Forschungszentrum Jülich GmbH, Projekt Management Jülich, Jülich, Germany; ⁴DIN - German Institute for Standardization, Berlin, Germany; ⁵Heidelberg Institute for Theoretical Studies (HITS gGmbH), Heidelberg, Germany

Benchmarking computational models of peritoneal dialysis in pigs and patients

Sangita Swapnasrita^1,2, Joost C deVries², Carl Oberg³, Aurelie MF Carlier¹, Karin GF Gerritsen²

¹Maastricht University, the Netherlands; ²UMC Utrecht, the Netherlands; ³Lund University, Sweden

Toward multiscale lymph node model: T cell search strategy study

Tomas Bily, Sára Štráchalová, Alžběta Prášilová

CUNI, Czech Republic

Software infrastructure tools for biomedical models in systems biology

Herbert Martin Sauro

University of Washington, United States of America

Probabilistic Boolean modelling highlights neural tube closure dynamics and molecular signalling insights

Ahmed Hemedan¹, Job Berkhout², Luiz Ladeira³, Alessio Gamba³, Harm Heusinkveld², Liesbet Geris^3,4, Bernard Staumont³, Rudi Balling⁵, Marek Ostaszewski^1,6, Venkata Satagopam^1,6, Reinhard Schneider^1,6

¹Luxembourg University, Luxembourg; ²Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; ³Biomechanics Research Unit, GIGA In Silico Medicine, University of Liège, Belgium; Skeletal Biology and Engineering Research Center, KU Leuven, Belgium; ⁴Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Belgium; ⁵Institute of Molecular Psychiatry, University of Bonn, Bonn, Germany; ⁶ELIXIR Luxembourg, Belvaux, Luxembourg

Explanatory models of human physiology to teach pathophysiology of diabetic ketoacidosis with simulators

Tomas Kulhanek, Jiri Kofranek

First Faculty of Medicine, Charles University Prague, Czech Republic

In silico clinical trial to predict the efficacy of alendronate for preventing hip fractures

Sophie Nguyen^1,2,3, Sara Oliviero^1,4, Giacomo Savelli^1,4, Antonino Amedeo La Mattina⁴, Marco Viceconti^1,4

¹Department of Industrial Engineering, Alma Mater Studiorum, University of Bologna, Italy; ²Faculty of Applied Sciences, University of Liège, Belgium; ³Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Belgium; ⁴Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Comparative assessment of lower limb joint angle estimation between BTS system and OpenSim

Mahshida Hamid¹, Sanyam Phutela¹, Rounak Bhattacharyya¹, Manish Gupta², Bhavuk Garg², Rajesh Malhotra^2,3, Madhusudan Pal^4,5, Anoop Chawla¹, Sudipto Mukherjee¹, Kaushik Mukherjee¹

¹Indian Institute of Technology Delhi, India; ²All Indian Institute of Medical Sciences, New Delhi, India; ³Indraprastha Apollo Hospital, New Delhi, India; ⁴Defense Institute of Physiology & Allied Science, Defence Research & Development Organisation, Delhi, India; ⁵Center of Excellence, Footwear Design & Development Institute, Noida, India

Quantification of periprosthetic bone loss using electrical impedance tomography

Lisa Krukewitt, Sascha Spors

University of Rostock, Germany

Machine learning framework to study the impact of metastatic cancer in the spine

Simão Laranjeira¹, Simon Walker-Samuel², Rebecca J. Shipley¹

¹UCL Mechanical Engineering, London, UK; ²UCL Centre for Computational Medicine, Division of Medicine, London, UK

A sustainable neuromorphic framework for disease diagnosis using AI

Rutwik Gulakala, Marcus Stoffel

RWTH Aachen, Germany

Limits and capabilities of diffusion models for the anatomic editing of digital twins

Karim Kadry¹, Shreya Gupta¹, Farhad R. Nezami², Elazer R. Edelman^1,2

¹MIT, United States of America; ²Brigham and Women's Hospital

Cross-disease predictive analysis for pandemic preparedness

Joana Elena Meyer¹, Sebastian Fritsch², Andreas Schuppert¹

¹Institute for Computational Biomedicine, RWTH Aachen, Germany; ²Departement of Intensive Care Medicine, University Hospital RWTH Aachen, Germany