Multiscale fluid-structure interaction for the effective modeling of vascular tissues

Luca Heltai², Camilla Belponer³, Alfonso Caiazzo¹, Lucas O. Müller⁴, Paolo Zunino⁵

1: WIAS Berlin, Germany; 2: University of Pisa; 3: University of Augsburg; 4: University of Trento; 5: Politecnico di Milano

An automated pipeline to investigate the impact of intracranial internal carotid artery calcifications on cerebrovascular events

Federica Fontana^1,2, Fennika S. C. Huijben^1,2, Aikaterini Tziotziou², Brian B. P. Berghout^3,4,5, Frank J. H. Gijsen^1,2, Ali C. Akyildiz^1,2, Selene Pirola¹

1: Department of Biomechanical Engineering, Delft University of Technology, Delft, The Netherlands; 2: Department of Biomedical Engineering, Erasmus Medical Center, Rotterdam, The Netherlands; 3: Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands; 4: Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands; 5: Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands

Impact of atrial rotor dominant frequency on flecainide and vernakalant cardioversion ratio

Violeta Puche-García¹, Laura Martínez-Mateu², David Filgueiras-Rama³, Lucía Romero¹, Javier Saiz¹

1: Centro de Investigación e Innovación en Bioingeniería (Ci2B), Universitat Politècnica de València, Spain; 2: Grupo de investigación de alto rendimiento en Ingeniería Biomédica y Ciencia de Datos (BigMed+), Universidad Rey Juan Carlos, Spain; 3: Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain

Predicting chronic cardiac responses to angiotensin receptor/neprilysin inhibitor using a physiological model of heart failure with preserved ejection fraction

John S. Clemmer¹, W. Andrew Pruett^1,2, Robert L. Hester^1,2, Marion R. Wofford¹

1: University of Mississippi Medical Center, United States of America; 2: HC Simulation

Coagulation cascade systems modeling for oral anticoagulant monitorization in atrial fibrillation patients

Maria Segarra-Queralt, Marina Ribera, Andy L. Olivares, Oscar Camara

BCN MedTech, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Spain

Hemodynamics of an implanted pressure sensor in porcine and human pulmonary artery

Leonid Goubergrits¹, Pavlo Yevtushenko¹, Adriano Schlief¹, Jan Romberg², Titus Kuehne¹, Andreas Arndt^2,3,4, Jan Bruening¹

1: Deutsches Herzzentrum der Charité, Berlin, Germany; 2: Biotronik, Berlin, Germany; 3: Technische Universität Dresden, Germany; 4: Kurt-Schwabe-Institut für Mess- und Sensortechnik Meinsberg e.V., Meinsberg, Germany

Turbulence modeling in aortic blood flow: Traditional models and perspectives on machine learning

Sarah Katz¹, Alfonso Caiazzo¹, Volker John^1,2

1: Weierstrass Institute for Applied Analysis and Stochastics, Germany; 2: Freie Universität Berlin, Germany

Estimation of exercise-induced pressure drop across aortic coarctations: A comparison of in vitro measurements and FSI simulations

Priya J. Nair^1,2, Emanuele Perra³, Doff B. McElhinney^1,2, Daniel B. Ennis^1,2,4, Alison L. Marsden^1,2, Seraina A. Dual³

1: Stanford University, USA; 2: Stanford Cardiovascular Institute, USA; 3: KTH Royal Institute of Technology, Sweden; 4: VA Palo Alto Healthcare System, USA

Simulation of the hemodynamics of a patient-specific artery at the full-body scale

Xiao-Chuan Cai

University of Macau, Macau S.A.R. (China)

A detailed 1D model of the feto-placental hemodynamics to investigate hypertensive disorders of pregnancy

Pascalle Wijntjes^1,2,3,4, Jérôme Kowalski³, Sjeng Quicken¹, Beatrijs van der Hout-van der Jagt^1,2,4, Irene Vignon-Clementel³, Frans van de Vosse^1,4, Wouter Huberts^1,4

1: Eindhoven University of Technology, Netherlands, The; 2: Máxima Medical Centre, the Netherlands; 3: INRIA, France; 4: e/MTIC, the Netherlands

The impact of clot permeability on thrombus growth in different hemodynamic scenarios

Niksa Mohammadi Bagheri, Gábor Závodszky, Alfons G. Hoekstra

Computational Science Lab, Informatics Institute, University of Amsterdam, Amsterdam, Netherland

Branching exponents of synthetic vascular trees under different optimality principles

Etienne Jessen¹, Marc C. Steinbach², Charlotte Debbaut³, Dominik Schillinger¹

1: Technical University of Darmstadt, Germany; 2: Leibniz University Hannover, Germany; 3: Ghent University, Belgium

Generation of organ-scale synthetic vasculature using mathematical optimization

Etienne Jessen¹, Marc C. Steinbach², Dominik Schillinger¹

1: TU Darmstadt, Germany; 2: Leibniz University Hannover, Germany

Modelling growth, remodelling and damage of arterial tissue: Application to cerebral vasospasm

Giulia Pederzani¹, Anne M. Robertson², Alfons G. Hoekstra¹, Paul N. Watton^2,3,4

1: Computational Science Lab, Informatics Institute, University of Amsterdam, Netherlands; 2: Department of Mechanical Engineering and Materials Science, University of Pittsburgh, USA; 3: Department of Computer Science, University of Sheffield, UK; 4: INSIGNEO Institute for in silico Medicine, University of Sheffield, UK

Computational modelling of coupled shear-induced NO signalling pathways in endothelial and smooth muscle cells of arterial walls

Fariba Bahadori, Merryn Tawhai, Alys Clark

University of Auckland, New Zealand

Do the clot mechanical properties affect the thrombectomy procedures? An in silico study

Virginia Fregona¹, Behrooz Fereidoonnezhad², Frank JH Gijsen^2,3, Jose Felix Rodriguez Matas¹, Francesco Migliavacca¹, Giulia Luraghi^1,2

1: Department of Chemistry, Materials and Chemical Engineering ‘Giulio Natta’, Politecnico di Milano, Italy; 2: Department of Biomechanical Engineering, Delft University of Technology, Delft, The Netherlands; 3: Department of Biomedical Engineering, Erasmus MC, Rotterdam, The Netherlands

CANCELLED - Efficient multiscale fluid flow modelling by a Stokes-enforcing boundary condition

Jeremías Garay^1,2, David Nolte¹, Cristóbal Bertoglio¹

1: University of Groningen, The Netherlands; 2: Pontificia Universidad Católica, Chile

An investigation into cerebral perfusion sensitivity under different haemodynamic and anatomical variations

Stephen A. Creamer¹, Finbar J. Argus¹, Debbie Zhao¹, Martyn P. Nash^1,3, Julian F. R. Paton², Gonzalo Maso Talou¹

1: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand; 2: Department of Physiology, Translational Cardio-Respiratory Laboratory, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand; 3: Department of Engineering Science and Biomedical Engineering, University of Auckland, Auckland, New Zealand

Inverse modelling approach to identify model parameters in 0D pulmonary haemodynamic simulation models

Yufei Wang, James Butterworth, Alejandro Diaz De La O, Rebecca Shipley, Ryo Torii

University College London, United Kingdom

Neural networks for efficient sensitivity analysis and parameter estimation of dynamical systems for blood and solute whole-body circulation

John M. Hanna, Pavlos Varsos, Jérôme Kowalski, Roel Meiburg, Irene E. Vignon-Clementel

Inria, Palaiseau, France

Comparison of 4D flow magnetic resonance imaging with blood flow simulations before and after left atrial appendage occlusion

Paula Casademunt¹, Xabier Morales Ferez¹, Jordi Mill¹, Carlos Albors¹, Íñigo Anduaga², Pedro Cepas², Ada Doltra², Xavier Freixa², Oscar Camara¹

1: Pompeu Fabra University, Department of Information and Communications Technologies, Barcelona, Spain; 2: Hospital Clínic, Universitat de Barcelona, Cardiovascular Institute, Barcelona, Spain

Quantitative perfusion assessment: A mechanistic model to interpret dynamic imaging

Jérôme Kowalski¹, Stefan Koning², Lorenzo Sala³, Roderick C. Peul², Mo W. Kruiswijk², Joost R. Van der Vorst², Irene Vignon-Clementel¹

1: Inria Saclay, France; 2: Leiden University Medical Center, The Netherlands; 3: Inrae, France

In silico pre-operative TEVAR planning: Application to a patient-specific case

Anna Ramella¹, Giulia Luraghi¹, Sara Barati¹, Maurizio Domanin^2,3, Santi Trimarchi^2,3, Francesco Migliavacca¹

1: Politecnico di Milano, Milan, Italy; 2: Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; 3: Università degli Studi di Milano, Milan, Italy

The role of secondary flow activities in the emergence of sidewall intracranial aneurysms

Benjamin Csippa, Péter Friedrich, György Paál

Budapest University of Technology and Economics, Faculty of Mechanical Engineering, Department of Hydrodynamics Systems,Hungary

Use of shape analysis and computational fluid dynamics for identification of factors relevant for aneurysm rupture

Ivan Benemerito¹, Luca Gherardini², Maria-Cruz Villa-Uriol¹, Andrew Narracott¹, Alberto Marzo¹, Jose Sousa²

1: Insigneo Institute for in silico medicine, University of Sheffield, United Kingdom; 2: Sano Centre for Computational Medicine, Krakow, Poland

Virtual particle tracking in geometries with cerebral aneurysms

Dániel Gyürki, György Paál

Department of Hydrodynamic Systems, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem rkp. 3., H-1111 Budapest, Hungary

Left atrial appendage occlusion: A virtual model to simulate the implant procedure in patient-specific scenarios

Francesca Danielli^1,2, Francesca Berti¹, Benigno Marco Fanni³, Emanuele Gasparotti³, Andrea Colella¹, Alessandro Vitozzi¹, Simona Celi³, Giancarlo Pennati¹, Lorenza Petrini²

1: Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Italy; 2: Department of Civil and Environmental Engineering, Politecnico di Milano, Italy; 3: BioCardioLab, Bioengineering Unit, Fondazione Monasterio, Italy

Left atrial wall dynamics in in-silico fluid simulations of atrial fibrillation patients

Carlos Albors¹, Nerea Arrarte Terreros^2,3,4, Josquin Harrison⁵, Xabier Morales¹, Marta Saiz Vivó¹, Nils Planken³, Joris R. de Groot⁴, Maxime Sermesant⁵, Oscar Camara¹

1: Universitat Pompeu Fabra, Barcelona, Spain; 2: Biomedical Engineering and Physics, Amsterdam University Medical Centers, Amsterdam, The Netherlands; 3: Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands; 4: Cardiology, Amsterdam University Medical Centers, Amsterdam, The Netherlands; 5: Inria, France

Multiscale computational model of blood flow of deployed vascular stents

Gabor Zavodszky, Christian Spieker, Alfons Hoekstra

University of Amsterdamm, Netherlands, The

Optimizing surgical outcomes in infants with ductal-dependent pulmonary blood flow conditions

Kevser Banu Köse, Wael Shamsi Basha, Mohamad Humam Alzaeim, Selma Mulla

Istanbul Medipol University, Turkiye

Optimization of braided stent deployment techniques

Reza Abdollahi^1,2, Simon Lessard^2,3, Rosaire Mongrain⁴, Gilles Soulez^1,2

1: Université de Montréal, H3T 1J4 Montreal, Canada; 2: Centre de Recherche du CHUM, H2X 0A9 Montréal, Canada; 3: École de Technologie Supérieure, H3C 1K3 Montreal, Canada; 4: Mechanical Engineering Department, McGill University, H3A 0C3 Montreal, Canada

Virtual coronary stenting simulations: On the use of data from patient-specific imaging for validation and clinical interpretation

Luca Antonini^1,2, Gianluca Poletti¹, Georgia S. Karanasiou^3,4, Antonis Sakellarios^3,4, Michail I. Papafaklis⁴, Lampros K. Michalis⁵, Dimitrios I. Fotiadis^3,4, Lorenza Petrini⁶, Giancarlo Pennati¹, Francesca Berti¹

1: LaBS - Department of Chemistry, Materials and Chemical Engineering “Giulio Natta”, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, Italy; 2: Parametric Design, Gessate (MI), Italy; 3: Department of Biomedical Research Institute–FORTH, University Campus of Ioannina, 45110 Ioannina, Greece; 4: 2nd Department of Cardiology, University Hospital of Ioannina, 45110 Ioannina, Greece; 5: Faculty of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece; 6: Department of Civil and Environmental Engineering, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, Italy

Effect of oversize stenting using a measurement-driven numerical approach for sidewall aneurysms

Levente Sándor, Benjamin Csippa, György Paál

Department of Hydrodynamic Systems, Faculty of Mechanical Engineering, Budapest University of Technology and Economics