Conference Agenda

11th Tinnitus Research Initiative (TRI) Meeting and TINNET Conference 2018

 
Date: Wednesday, 14/Mar/2018
11:00am - 12:30pmSession 2: Tinnitus Animal Models
Session Chair: Holger Schulze
Second Lecture Hall 
 

Tinnitus development is associated with synaptopathy of inner hair cells in Mongolian gerbils

Konstantin Tziridis, Jan Forster, Patrick Krauss, Achim Schilling, Holger Schulze

University Hospital Erlangen, Germany


A new statistical approach for the evaluation of gap-prepulse inhibition of the acoustic startle reflex (GPIAS) for tinnitus assessment

Achim Schilling, Patrick Krauss, Konstantin Tziridis, Holger Schulze

University of Erlangen-Nuremberg, Germany


A Tinnitus Model in Nonhuman Primates

Lars Rogenmoser, Pawel Kusmierek, Denis Archakov, Josef Rauschecker

Georgetown University Medical Center


Cross-validation of Two Tinnitus Screening Approaches in Mice

Inga Kristaponyte, Alex Galazyuk

Northeast Ohio Medical University (NEOMED), United States of America


Changes in gamma frequency activity in the auditory cortex in vitro in an animal model of tinnitus

Mark O. Cunningham1, Gina Rentesi1, Jennifer Schofield2, Martine Hamann2, Guiseppe Alvaro3, Charles A. Large3, Adrian Rees1

1Newcastle University, United Kingdom; 2University of Leicester, United Kingdom; 3Autifony Therapeutics Ltd, Hertfordshire, United Kingdom

 
2:30pm - 3:45pmSession 4: Cortical Tinnitus Networks
Session Chair: Josef P. Rauschecker
Second Lecture Hall 
 

Amygdala functional disconnection with the prefrontal-cingulate-temporal circuit in chronic tinnitus patients with depressive mood

Yu-Chen Chen, Fan Bo, Xindao Yin

Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China, China, People's Republic of


Resting state EEG microstate in tinnitus patients reveals dynamic changes in attention and auditory cortical networks during residual inhibition

Ann Deklerck1, Hannah Keppler2,3, Katharina Paul4, Sofie Degeest3, Ingeborg Dhooge1,2, Gilles Pourtois4

1Department of Otorhinolaryngology, Ghent University, Ghent, Belgium; 2Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium; 3Department of Speech-, Language-, and Hearing Sciences, Ghent University, Ghent, Belgium; 4Department of Experimental-Clinical and Health Psychology, Ghent University, Ghent, Belgium


AUDITORY EVOKED MAGNETIC FIELD SIGNATURES OF DYNAMIC RANGE ADAPTATION OF SOUND LEVEL CODING IN TINNITUS PATIENTS AND HEALTHY CONTROLS.

Eugen Diesch, Anna Hassel, Ben Cramer, Mark Praetorius, Sabine Heiland, André Rupp

U Heidelberg, Germany


New ways forward in Tinnitus Research?

Josef P. Rauschecker1,2

1Georgetown University, United States of America; 2Hans Fischer Senior Fellow, Institute for Advanced Study, Technical University Munich

 
4:15pm - 5:00pmSession 6: Towards a consensus of outcome measures on tinnitus
Session Chair: Deborah Ann Hall
Second Lecture Hall 
 

INTERACTIVE CONSENSUS WORKSHOP FOR THE COMiT’ID STUDY: INTERNATIONAL CONSENSUS ON CORE OUTCOME DOMAINS FOR EARLY-PHASE CLINICAL TRIALS OF SOUND-, PSYCHOLOGY-, AND PHARMACOLOGY-BASED INTERVENTIONS TO MANAGE CHRONIC SUBJECTIVE TINNITUS IN ADULTS: THE COMIT’ID STUDY

Deborah Ann Hall1,2, Kathryn Fackrell1,2, Harriet Smith1,2, Haúla Haider3, Birgit Mazurek4, Alain Londero5

1NIHR Nottingham Biomedical Research Centre, Ropewalk House, 113 The Ropewalk, Nottingham, NG1 5DU; 2Otology and Hearing Group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, NG7 2UH; 3ENT Department of Hospital Cuf Infante Santo - Nova Medical School, Travessa do Castro, 3. 1350-070 Lisbon, Portugal; 4Tinnitus Center, Charite University Hospital, Chariteplatz 1, 10117 Berlin, Germany; 5Service ORL et CCF, Consultation Acouphène et Hyperacousie, Hôpital Européen G. Pompidou, 20, rue Leblanc, 75015 Paris, France

 

 
Date: Thursday, 15/Mar/2018
9:00am - 10:15amSession 8: Looking at tinnitus from a different angle
Second Lecture Hall 
 

“My goodness, that really does actually sum it up:” tinnitus patients’ and therapists’ perspectives on the cognitive model of tinnitus distress

Lucy Handscomb1, Derek Hoare1, Deborah Hall1, Gillian Shorter2

1NIHR Nottingham Biomedical Research Centre, United Kingdom; 2Alcohol and Public Health Team, Teesside University, United Kingdom


Putative factors for chronic manifestation of tinnitus

Veronika Vielsmeier

University of Regensburg, Germany


Cochlear migraine: proposal for a new diagnosis

Tien-Chen Liu, Jen-Tsung Lai

National Taiwan University Hospital, Taiwan


Patient Empowerment through Summarization of Discussion Threads on Treatments in a Patient Self-Help Forum

Myra Spiliopoulou1, Sourabh Dandage1, Johannes Huber1, Atin Janki1, Uli Niemann1, Rüdiger Pryss2, Manfred Reichert2, Steve Harrison3, Markku Vessala3, Winfried Schlee4, Thomas Probst5

1Otto-von-Guericke University Magdeburg, Germany; 2Universität Ulm; 3Tinnitus Talk; 4Universität Regensburg; 5Universität Krems


Modulating individual frustration: a new approach to tinnitus management?

Nicolas Dauman1, Soly Erlandsson2, René Dauman3

1University of Poitiers, Poitiers, France (EA4050, Department of Psychology); 2University West, Trollhättan, Sweden (Department of Social and Behavioural Studies); 3University of Bordeaux, Bordeaux, France (INCIA, UMR Centre National de la Recherche Scientifique)

 
10:30am - 11:45amSession 10: Interesting Case Studies in Tinnitus
Session Chair: Tanit Ganz Sanchez
Second Lecture Hall 
 

Combining rTMS and CBT for Effective Treatment of Tinnitus and Insomnia - A Case Report

Lukas Peter1, Kneginja Richter1,2,3, Jens Acker4, Joachim Höfig1

1Universitätsklinik für Psychiatrie und Psychotherapie, Paracelsus Medizinische Privatuniversität, Nürnberg, Germany; 2Technische Hochschule Georg Simon Ohm, Nürnberg, Germany; 3University Goce Delčev, Štip, Macedonia; 4Klinik für Schlafmedizin, Bad Zurzach, Switzerland


The Role of Auditory Evoked Potentials in the Study of Tinnitus. About a Case.

SHEILA TEMPLADO AGUILERA, Luis Miguel Amorós-Rodriguez

COIMBRA UNIVERSITY, Spain


The putative involvement of the middle ear in hyperacusis and tinnitus

Philippe Fournier, Damien Ponsot, Alain Londero, Laurent Pezard, Nicolas Charpentier, Arnaud Norena

CNRS, France

 
2:00pm - 3:15pmSession 12: New treatment Approaches for Tinnitus
Session Chair: ALAIN LONDERO
Second Lecture Hall 
 

Menopausal Hormone replacement therapy for chronic tinnitus in migraine patient: a preliminary study

Chiung-Lin Liu1, Tien-Chen Liu2, Jen-Tsung Lai3

1Department of Otolaryngology, Kuan-Tien General Hospital, Taichung, Taiwan; 2Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan; 3Department of Otolaryngology, Kuan-Tien General Hospital, Taichung, Taiwan


The value of Eye Movement Desensitization Reprocessing in the treatment of tinnitus

Tine Roanna Luyten1,2,4, Prof. dr. Paul Van de Heyning1,2, Laure Jacquemin1,2, Nancy Van Looveren4, Dr. Frank Declau1, Prof. Erik Fransen1,2, Prof. Annick Gilles1,2,3

1Faculty of Medicine and Health Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium; 2University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, Belgium; 3Department of Human and Social Welfare, University College Ghent, Ghent, Belgium; 4Hoorzorg Van Looveren BVBA, Herentalsebaan 275, 2150 Borsbeek, Belgium


Tinnitus outcome measures after a brief multidisciplinarity intervention

Petra Brüggemann, Benjamin Böcking, Claudia Seydel, Birgit Mazurek

Charité Universitätsmedizin Berlin, Germany


Auditory-somatosensory stimulation desynchronizes brain circuitry to reduce tinnitus, Part I

Calvin Wu, David Martel, Susan Shore

University of Michigan, Ann Arbor, United States of America


Auditory-somatosensory stimulation desynchronizes brain circuitry to reduce tinnitus, Part II

Kendra Marks1, David Martel1, Gregory Basura1, Larry Roberts2, Kara Schvartz-Leyzac1, Susan Shore1

1University of Michigan, Ann Arbor, United States of America; 2McMaster University, Hamilton, Ontario, Canada

 
3:30pm - 5:00pmSession 14: Community Science: How can participatory research improve our current research strategies?
Session Chair: Patrick Neff
Second Lecture Hall 
 

INVOLVING MEMBERS OF THE PUBLIC IN THE COMIT’ID STUDY (CORE OUTCOME MEASURES IN TINNITUS: INTERNATIONAL DELPHI)

Deborah Ann Hall1,2, Kathryn Fackrell1,2, Adele Horobin1,3, Veronica Colley1, Brian Thacker1, Haúla Haider4, Birgit Mazurek5, Alain Londero6, Harriet Smith1,2

1NIHR Nottingham Biomedical Research Centre, Ropewalk House, 113 The Ropewalk, Nottingham, NG1 5DU; 2Otology and Hearing Group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, NG7 2UH; 3Nottingham University Hospitals NHS Trust. Queens Medical Centre, Derby Road, Nottingham, NG7 2UH; 4Hospital Cuf Infante Santo - Nova Medical School, Portugal.; 5Tinnitus Center, Charité University Hospital, Germany; 6Consultation Acouphène et Hyperacousie, Hôpital Européen G. France.


CORE OUTCOME DOMAINS FOR EARLY-PHASE CLINICAL TRIALS OF SOUND-, PSYCHOLOGICAL-, AND PHARMACOLOGICAL-BASED INTERVENTIONS TO MANAGE CHRONIC SUBJECTIVE TINNITUS IN ADULTS: PROTOCOL FOR USING A DELPHI PROCESS AND FACE-TO-FACE MEETINGS TO ESTABLISH CONSENSUS

Kathryn Fackrell1,2, Harriet Smith1,2, Adele Horobin1,3, Veronica Colley1, Brian Thacker1, Haúla Haider4, Alain Londero5, Birgit Mazurek6, Deborah A. Hall1,2

1NIHR Nottingham Biomedical Research Centre, Ropewalk House, 113 The Ropewalk, Nottingham, NG1 5DU; 2Otology and Hearing Group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, NG7 2UH; 3Nottingham University Hospitals NHS Trust. Queens Medical Centre, Derby Road, Nottingham, NG7 2UH; 4Hospital Cuf Infante Santo - Nova Medical School, Portugal.; 5Consultation Acouphène et Hyperacousie, Hôpital Européen G. France.; 6Tinnitus Center, Charité University Hospital, Germany


Tinnitus Cure Map

David Stockdale1, Dave Carr1, Don McFerran2

1British Tinnitus Association, United Kingdom; 2Colchester Hospital University NHS Foundation Trust


Combined amplification and sound generation devices for tinnitus: survey of users expectations and experiences

Magdalena Sereda1,2, Derek Hoare1,2, Julie Brady3

1NIHR Nottingham Biomedical Research Centre, Nottingham, United Kingdom; 2Otology and Hearing Group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK; 3Nottingham University Hospitals NHS Trust, Nottingham, UK


Tinnitus Hub: Support and Crowdsensing in the digital domain

Stephen Sebastian Harrison

Tinnitus Hub, United Kingdom

 

 
Date: Friday, 16/Mar/2018
9:30am - 10:45amSession 16: A very close look on tinnitus: the genes and molecules that make up tinnitus
Session Chair: Jose Antonio Lopez Escamez
Second Lecture Hall 
 

Accumulation of rare and common variants in genes included in multiple neural pathways in a family with tinnitus

Jose Antonio Lopez Escamez, Alvàro Gallego-Martinez, Niklas Edvall, Teresa Requena, Christopher Cederroth

Center for Genomics -Genyo, Spain


A pilot Genome-wide Association Study identifies potential metabolic pathways involved in tinnitus

Annick Gilles1,2,3, Guy Van Camp4, Paul Van de Heyning1,2, Erik Fransen4,5

1Faculty of Medicine and Health Sciences, Dept. Translational Neuroscience, University of Antwerp, Wilrijk, Belgium; 2Univ. Dept. of Otorhinolaryngology and Head & Neck Surgery, Antwerp University Hospital, Edegem, Belgium; 3Dept. of Human and Social Welfare, University College Ghent, Ghent, Belgium; 4Center for Medical Genetics, Antwerp University Hospital and University of Antwerp, Antwerp, Belgium; 5StatUa Center for Statistics, University of Antwerp. Antwerp, Belgium


Identification of functional and molecular biomarkers in mildly hearing impaired subjects with and without tinnitus

Marlies Knipper1, Benedikt Hofmeier1, Ebrahim Saad Aldamer1, Moritz Walter1, Stephan Wolpert1, Lukas Rüttiger1, Ulrike Ernemann3, John Thiericke1, Uwe Klose2

1Dept. of Otolaryngology, Tübingen Hearing Research Center (THRC), University Hospital of Tübingen,Germany; 2Dept. of Neuroradiology, University Hospital of Tübingen, Tübingen Germany; 3Dept. of Diagnostic and Interventional Neuroradiology, University Hospital of Tübingen, Tübingen Germany


Expressions of ion co-transporter genes in salicylate-induced tinnitus and treatment effects with Spirulina

Juen-Haur Hwang1,2, Yin-Ching Chan3, Jen-Tsung Lai4, Tien-Chen Liu5

1Dept of Otolaryngology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical; 2School of Medicine, Tzu Chi University, Hualien, Taiwan.; 3Department of Food and Nutrition, Providence University, Taichung, Taiwan.; 4Deparment of Otolaryngology, Kuang-Tien General Hospital, Shalu, Taichung, Taiwan; 5Deparment of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan

 
11:00am - 12:15pmSession 18: Cochlear Implants for treating Tinnitus
Session Chair: Tobias Kleinjung
Session Chair: Griet Mertens
Second Lecture Hall 
 

Cochlear Implantation as a Long-Term Treatment for Ipsilateral Incapacitating Tinnitus in Subjects with Unilateral Hearing Loss up to 10 years.

Griet Mertens1,2, Marc De Bodt1,2, Annick Gilles1,2, Paul Van de Heyning1,2

1Univ. Dept. Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Belgium; 2University of Antwerp, Belgium


TINNITUS OUTCOMES IN COCHLEAR IMPLANTED PATIENTS WITH TOTAL SINGLE-SIDED DEAFNESS: A MULTICENTRIC STUDY

Elisabeth MAMELLE1, Bruno Frachet1, Christophe Vincent2, David Bakhos3, Benoit Godey4, Olivier Sterkers5, Isabelle Mosnier5, Eric Truy6, Nicolas Guevara7, Michel Hoen8, Dan Gnansia8, Christine Poncet-Wallet1

1AP-HP, Hôpital Rothschild, France; 2CHRU Lille, hôpital Roger Salengro, Service ORL, Lille, France; 3CHU Tours Bretaonneau, Service ORL, Tours, France; 4CHU Rennes Pontchaillou, Service ORL, Rennes, France; 5AP-HP, GH Pitié-Salpétrière, service ORL, Paris, France; 6CHU Lyon, Hôpital Edouard Herriot, Service ORL, Lyon, France; 7IUFC – CHU Nice, Service ORL , Nice, France; 8Oticon medical, Clinical and scientific research group cochlear implant, Vallauris, France


Tinnitus suppression in cochlear implant patients using the ReSound Relief™ app

Richard S Tyler1, Rachael Owen1, Julie Bridges2, Patricia Cotta Mancini1, Phillip E. Gander1

1University of Iowa, United States of America; 2GNresound


Cochlear Implantation for Tinnitus in Subjects with Hearing Loss

Lieber Po-Hung Li1,2

1Department of Otolaryngology, Cheng Hsin General Hospital, Taipei, Taiwan; 2Faculty of Medicine, National Yang Ming University, Taipei, Taiwan

 
2:30pm - 3:45pmSession 20: Panel discussion: Throwing the ball further: What tinnitus research can learn from Team New Zealand’s winning of yachting’s Americas Cup
Session Chair: Berthold Langguth
Session Chair: Ana Belén Elgoyhen
Second Lecture Hall 
 

Throwing the ball further: What tinnitus research can learn from Team New Zealand’s winning of yachting’s Americas Cup.

Grant Donald Searchfield

The University of Auckland, New Zealand

Winning yachting’s Americas cup and curing tinnitus are no small feats. Both were goals of Emirates Team New Zealand's (ETNZ) principal, and founder of the Tinnitus Research Initiative, Matteo de Nora. The first goal was achieved in 2017 after many years of trying; the later goal remains unattained. Tinnitus research may not seem to share much in common with yachting, but in order to win the world’s oldest sporting trophy ETNZ faced financial, technical and methodological issues not dissimilar to the challenges we face in tinnitus research. ETNZs victory was not based on incremental improvements in design and performance, but instead a philosophy of “throwing the ball out as far as we can and see if we can get to it”. While scientific method and funders favor safe, or proven, research we may miss opportunities to rapidly advance our field if we do not take risks. This talk will use ETNZ as a sporting analogy for how we can change the tinnitus research space by emboldening researchers to take greater risks. Four themes for success will be explored; innovation, risk, persistence and people.