Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
Inventory-responsive donor management policy: A tandem queueing network model
Nicholas Teck Boon Yeo1, Taozeng Zhu2, Gar Goei Loke3, Yini Gao1
1Singapore Management University, Singapore; 2Dongbei University of Finance and Economics; 3Erasmus University
In the blood donor management problem, the blood bank incentivizes donors to donate, given blood inventory levels. We propose an optimization model to design donor incentivization schemes that account for the blood inventory dynamics and the donor's donation process. By adopting the Pipeline Queue paradigm, we have a tractable convex reformulation. Numerical results show the advantages of the optimal policy compared with benchmark policies in reducing both shortages and wastage.
Inventory management and shipment policies for clinical trials
Philippe Chevalier1, Alejandro Lamas2
1Universite catholique de Louvain, Belgium; 2NEOMA Business School, France
Clinical trials are a critical step for the development of new drugs, both in
cost and in terms of elapsed time to bring the potential drug to the market. Since clinical trials are increasingly going global, optimizing the supply chain can bring huge benefits. We use a MDP to model the inventory problem between the central depot and the regional depots that will then supply the investigation sites. The main decision is when to resupply and how much inventory to send to each regional depot.
Reshaping organ allocation policy through multi-objective optimization
Theodore Papalexopoulos1, Dimitris Bertsimas1, Nikolaos Trichakis1, James Alcorn2, Rebecca Goff2, Darren Stewart2
1MIT, United States of America; 2UNOS, United States of America
The Organ Procurement & Transplantation Network (OPTN) is migrating all US organ allocation policies to a novel continuous-distribution model. We introduce a novel analytical framework to illuminate policy tradeoffs and enable exploration of the efficient frontier of policies. Jointly with the OPTN, we applied our framework to the design of a new allocation policy for lungs. Starting in 2023, all deceased-donor lungs in the US will be allocated according to this policy.
