This study presents the application of UAV-based LiDAR and aerial photogrammetry for the detailed mapping and morphometric analysis of karst features in the Sete Lagoas region, Brazil. Thirteen karst depressions were identified, including eight caprock dolines and five karst lagoons, based on high-resolution elevation models and structural geological field data. The integration of geomorphological and structural information enabled a precise characterization and volumetric estimation of the features using GIS-based methods. The results provide essential insights into the karst system’s morphology and contribute to the development of thematic cartographic products. These products may support future investigations on groundwater recharge and enhance regional strategies for the sustainable management of water resources in an area strongly reliant on a karst aquifer.