Anthropogenic changes such as deforestation and agricultural expansion are changing Earth's ecosystems, especially in vulnerable regions like the Brazilian Pantanal. Recognized as a biodiversity hotspot and a wetland of international importance, the Pantanal faces critical environmental pressures. In this context, this research analysing spatiotemporal land use dynamics using geospatial technologies in the Brazilian Pantanal. Were employed the Land Cover Indicator, representing physical phenomena associated with land use characteristics. Our land use and land cover data were sourced from MapBiomas, utilizing a two-year dataset (2022-2024) to conduct a spatiotemporal analysis of land use dynamics. The results showed a decrease in water bodies, mainly in the central-southern region of the study area. Additionally, the results highlight a transition from forests to pastures, resulting in an average increase of 2.22% in the land cover indicator over the period. Wetlands and water bodies showed a combined decrease of 10.27%. It is crucial to understand these relationships through spatial analysis to develop effective environmental conservation strategies and maintain sustainable management of this globally important wetland.