A continuous-wave spectroscopic singlet oxygen sensor for photodynamic therapy dosimetry: Preclinical studies in a murine model of actinic keratosis

Sanjay Anand^1,2,3, Tiffany Yu⁴, Cheng-En Cheng¹, Steven J Davis⁴, Youbo Zhao⁴, Edward V Maytin^1,2,3

¹1Department of Biomedical Engineering, Cleveland Clinic, United States of America; ²Dermatology and Plastic Surgery Institute, Cleveland Clinic, United States of America; ³Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, United States of America; ⁴Physical Sciences Inc., 20 New England Business Center Drive, Andover, MA, U.S.A.

A novel chlorin e6 derivative-mediated photodynamic therapy STBF-PDT reverses photoaging via the TGF-β pathway

JingJuan Shi¹, Qingyu Zeng², Peiru Wang², Qihang Chang², Jianhua Huang¹, Minfeng Wu¹, Xiuli Wang², Hongwei Wang¹

¹Department of Dermatology, Huadong Hospital, Fudan University, Shanghai 200040, China; ²Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200050, China

Advanced treatment of giant proliferating trichilemmal tumor: limited resection combined with neoadjuvant ALA-PDT

Caihe Liao¹, Mingshun Wu¹, Yeqiang Liu², Xiuli Wang¹, Guolong Zhang¹

¹Department of Phototherapy at Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China; ²Department of Pathology, Shanghai Skin Disease Hospital, Tongji University, Shanghai, China

Carbon dioxide laser combined with ALA photodynamic therapy for Porokeratosis: a case report

Li Wei, Mutong Zhao, Lin Ma

Department of Dermatology, Beijing Children’ s Hospital, Capital Medical University, National Center for Children’ s Health, Beijing, China, China, People's Republic of

Clinical study on electrocautery combined with ALA- photodynamic therapy for condyloma acuminatum in children

Li Wei¹, Lingyun Zou², Bei Li¹, Yabin Zhou¹, Lin Ma¹

¹Department of Dermatology, Beijing Children’ s Hospital, Capital Medical University, National Center for Children’ s Health, Beijing, China, China, People's Republic of; ²Beijing New Century International Children's Hospital,Beijing,100045

Combination of High-frequency Electrocautery Therapy and ALA-PDT in Hyperkeratotic Vulvar Lichen Sclerosus: series of seven cases

Huiyan Deng, Huanli Wang, Wenjun Zhang, Huaping Li, Huilan Zhu

Guangzhou Institute of Dermatology , Department of Dermatology, Guangzhou,China

Comparison of spectroscopic and fluorescent video analysis for phototheranostics of cholangiocellular cancer

Dmitry Yakovlev^1,2, Artem Shiryaev³, Kanamat Efendiev¹, Kirill Linkov¹, Igor Reshetov³, Maxim Loschenov⁴, Victor Loschenov¹

¹Prokhorov General Physics Institute of Russian Academy of Sciences; ²Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences; ³University Clinical Hospital No. 1, Oncology Center, I.M. Sechenov First Moscow State Medical University (Sechenov University) Ministry of Health of the Russian Federation; ⁴LLC BIOSPEC

Curcumin in photoresponsive micelles for antimicrobial Photodynamic Therapy

Jeffersson Krishan Trigo-Gutierrez¹, Italo Rodrigo Calori², Ana Cláudia Pavarina¹, Antonio Claudio Tedesco², Ewerton Garcia de Oliveira Mima¹

¹São Paulo State University (Unesp), School of Dentistry, Araraquara, Brazil; ²Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Ribeirão Preto

Development of Thin-Film Light-Emitting Devices for Hyper Localized Photodynamic Therapy

Masato Saito¹, Takahiro Nomoto², Yasufumi Yokoshiki³, Takashi Tokuda³, Toshinori Fujie^1,4

¹Tokyo Institute of Technology, School of Life Science and Technology, Yokohama, Japan; ²Tokyo Institute of Technology, Laboratory for Chemistry and Life Science, Yokohama, Japan; ³Tokyo Institute of Technology, School of Engineering, Tokyo, Japan; ⁴Tokyo Institute of Technology, International Research Frontiers Initiative (IRFI), Yokohama, Japan

Effectiveness of 5-aminolevulinic acid photodynamic therapy with intense pulsed light in Chinese patients with mild to moderate acne vulgaris

Qihang Chang, Xiaojing Liu, Peiru Wang, Linglin Zhang, Xiuli Wang

Institute of Photomedicine, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200092, P. R. China

Effects of metalation on the PDT activity of arene ruthenium porphyrin-based photosensitizers on prostate cancer

Lucie Paulus¹, Manuel Gallardo-Villagran^1,2, Bruno Therrien², David Yannick Léger¹, Bertrand Liagre¹

¹Univ. Limoges, LABCiS UR 22722, Faculté de Pharmacie, F-87000 Limoges, France; ²Université de Neuchâtel, Institut de Chimie, Neuchâtel, Suisse

Experimental modelling of heating and local field enhancement by iron oxide nanoparticles upon laser excitation

Anastasia Ryabova, Daria Pominova, Inessa Markova, Aleksey Nikitin, Petr Ostroverhov, Ekaterina Plotnikova, Natalia Morozova, Igor Romanishkin, Maksim Abakumov, Andrey Pankratov, Rudolf Steiner, Victor Loschenov

Prokhorov General Physics Institute of the Russian Academy of Sciences, Russian Federation

Fluorescence-Guided Resection and Photodynamic Therapy of Glioblastoma with Combined Use of 5-ALA and Chlorin e6 Photosensitizers

Elizaveta Kozlikina¹, Igor Trifonov², Mikhail Sinkin², Vladimir Krylov³, Victor Loschenov^1,4

¹National Research Nuclear University MEPhI, Russian Federation; ²Federal State Budgetary Educational Institution of Higher Education “A.I. Evdokimov Moscow State University of Medicine and Dentistry”, The Ministry of Healthcare of the Russian Federation, Moscow, Russia; ³Federal State Autonomous Educational Institution of Higher Education “N.I. Pirogov Russian National Research Medical University”, The Ministry of Health of the Russian Federation, Moscow, Russia; ⁴Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia

Hemoporfin photodynamic therapy of limb port-wine stains resistant to pulsed dye laser therapy: a case report

Kunqian Huang, Xinyu Zhang, Sijian Wen, Wenjun Zheng

The First Affiliated Hospital of Guangxi Medical University, China, People's Republic of

HMME-PDT applied in PWS

Minglan Shi^1,2, Changxing Li¹, Kang Zeng¹

¹Southern Medical University, Nanfang Hospital, Department of Dermatology, Guangzhou, China; ²The University of Hong Kong‑Shenzhen Hospital, Department of Dermatology, Shenzhen, China.

Hypericin - a natural photosensitizer in photodynamic therapy on skin cancer cells

Martyna Nowak-Perlak, Marta Woźniak, Piotr Ziółkowski

Department of Clinical and Experimental Pathology, Division of General and Experimental Pathology, Wroclaw Medical University, Poland

Influence of temperature on the photodynamic inactivation of Aedes aegypti larvae and hatching

Matheus Garbuio^1,2, Alessandra Ramos Lima², Kamila Jessie Sammarro Silva², Mariana de Souza², Natalia Mayumi Inada², Vanderlei Salvador Bagnato^2,3

¹Federal University of São Carlos, São Carlos, Brazil; ²São Carlos Institute of Physics, University of São Paulo, São Carlos, Brazil; ³Hagler Fellow, Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA

Modified 5-aminolevulinic acid photodynamic therapy (M-PDT) provokes cutaneous squamous cell carcinoma cell pyroptosis

Diyan Chen, Qingyu Zeng, Xiuli Wang

Shanghai Skin Disease Hospital, School of Medicine, Tongji University, China, People's Republic of

Nanobody targeted photodynamic therapy induces cell death of HER2-positive tumor cells

Tomohiro Osaki¹, Natsuho Takeda¹, Takashi Iwasaki¹, Tetsuya Kadonosono², Takahiro Nomoto³

¹Department of Agriculture, Tottori University, Japan; ²School of Life Science & Technology, Tokyo Institute of Technology, Japan; ³Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Japan

Optimization of energy parameters for laser-induced photodynamic therapy of cervical tissues using numerical simulation and fluorescent navigation

Polina Alekseeva¹, Kanamat Efendiev^1,2, Tatyana Savelieva^1,2, Arkady Moskalev¹, Aida Gilyadova³, Victor Loschenov^1,2

¹Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia; ²National Research Nuclear University MEPhI, Moscow, Russia; ³Sechenov First Moscow State Medical University, Moscow, Russia

Oxygen levels in glioblastoma before and after PDT with theranostic AGuIX® nanoparticles

Ewa Kowolik¹, Aleksandra Bienia¹, Michal Gonet¹, Agnieszka Drzal¹, Krystyna Urbanska¹, Patrycja Nowak-Sliwinska², Martyna Elas¹

¹Jagiellonian University, Cracow, Poland; ²University of Geneva, Geneva, Switzerland

Photoactive bilayer nanofiber membranes doped with photosensitizer and silver nanoparticles for enhanced antibacterial applications

Robert Willimetz¹, Petra Křtěnová¹, Pavel Kubát², Jiří Mosinger¹

¹Faculty of Science, Charles University, 2030 Hlavova, 128 43 Prague 2, Czech Republic; ²J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, v.v.i., Dolejškova 3, 182 23 Prague 8, Czech Republic

Photodynamic Therapy of Head and Neck Cancers with Ruthenium-based Photosensitizers

Chloé Thibaudeau¹, Gilles Gasser², Christian Gaiddon¹, Alain Jung^1,3

¹Laboratory Streinth, University of Strasbourg, Inserm UMR_S 1113 IRFAC, 67200 Strasbourg, France; ²Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005 Paris, France; ³Tumor Biology Laboratory, Strasbourg Europe Cancer Institute, 67200 Strasbourg, France

Photosensitizer delivered by loaded macrophages mediate effective PDT

Catherine Christie, Henry Hirschberg

Beckman Laser Institute and Medical Clinic, UC Irvine, United States of America

Postdoctoral researcher

Xue Qin¹, Gilles Gasser², Christian Gaiddon¹, Alain Jung³

¹Laboratory Streinth, University of Strasbourg, Inserm UMR_S 1113 IRFAC; ²Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology; ³Tumor Biology Laboratory, Strasbourg Europe Cancer Institute

Potential therapeutic efficacy of Photodynamic Therapy on triple negative breast cancer in hormonal microenvironment

Kivi Cheuk-nam Cheung¹, Grace Man-ngai Leung¹, Ricky Wing-kei Wu², John Wai-man Yuen³, Zheng Huang⁴, Ellie Shihng-meir Chu¹

¹School of Medical and Health Sciences, Tung Wah College, Hong Kong S.A.R. (China); ²Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland, United Kingdom; ³School of Nursing, Hong Kong Polytechnic University, Hong Kong S.A.R. (China); ⁴MOE Key Laboratory of Photonics Science and Technology for Medicine, Fujian Normal University, Fuzhou, China

Self-Assembly for therapy: Phthalocyanine nanostructures

Mireia Jordà-Redondo¹, Irene Paramio², Ainhoa Salazar², Tomás Torres², Gema de la Torre², Santi Nonell¹

¹Universitat Ramon Llull, Spain; ²Universidad Autónoma de Madrid, Spain

Structure-activity studies of di-cationic imidazolyl porphyrins for PDI of E. coli

Madalena F. C. Silva¹, Rafael T. Aroso¹, Zoe A. Arnaut¹, Janusz M. Dabrowski², Barbara Pucelik², Agata Barzowska², Gabriela J. da Silva³, Luís G. Arnaut¹, Mariette M. Pereira¹

¹Coimbra Chemistry Center, Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal; ²Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Krakow, Poland; ³Faculty of Pharmacy and Center for Neurosciences and Cell Biology, University of Coimbra, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal

The effect of local photodynamic therapy with 5-aminolevulinic acid in the treatment of recurrent cervical and vaginal high-grade squamous intraepithelial lesions following surgery

Mengzhen Zhang, Yuehui Su, Chunyan Zhang, Ting Zhang, Bingjie Wang, Mengjiao Zhou, Shuyu Yuan, Mengzhuo Zhang

The First Affiliated Hospital of Zhengzhou University, China, People's Republic of

The Effects of photodynamic therapy on the immune cells in women with cervical high-grade squamous intraepithelial lesions (HSIL/CIN2)

Lihua Qiu, Anyue Wu

Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine, China, People's Republic of

The method development for assessing the depth of ethosomes with methylene blue penetration into the skin during application and photodynamic exposure

Anna Loginova¹, Irina Nikitenko²

¹National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow, Russia, Kyrgyzstan (Kyrgyz Republic); ²Clinic of Aesthetic Cosmetology and Dermatovenerology ”EsteMed" Ltd

The use of methylene blue to control the tumor oxygenation level

Daria Pominova^1,2, Anastasia Ryabova^1,2, Aleksej Skobeltsin^1,2, Inessa Markova², Igor Romanishkin¹

¹Prokhorov General Physics Institute of the Russian Academy of Sciences; ²National Research Nuclear University MEPhI

Treatment of Nevus Sebaceous with Short-term Photodynamic therapy combined with simple Surgery

Jiaoquan Chen, Nanji Yu, Huilan Zhu

Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, Guangdong 510095, China.

Tumor fluorescence and oxygenation monitoring during photodynamic therapy with chlorin e6 photosensitizer

Kanamat Efendiev^1,2, Polina Alekseeva¹, Artem Shiryaev³, Arina Voitova⁴, Igor Reshetov³, Victor Loschenov^1,2

¹Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia; ²National Research Nuclear University “MEPhI”, Moscow, Russia; ³Sechenov First Moscow State Medical University, Moscow, Russia; ⁴BIOSPEC Ltd., Moscow, Russia

Use of a cationic di-imidazolyl chlorin for antimicrobial photodynamic therapy

Anita Amorim¹, Zoé Arnaut¹, Gabriela Silva², Mariette Pereira¹, Luís Arnaut¹

¹Chemistry Department, University of Coimbra, Coimbra, Portugal; ²Faculty of Pharmacy and Center for Neurosciences and Cell Biology, University of Coimbra

PDT in Neuro-oncology

Shaoshan Yan, Shaoshan Hu

People's Hospital of Hangzhou Medical College: Zhejiang Provincial People's Hospital, China

Chlorin-e6 conjugated to the Antimicrobial Peptide LL-37 loaded Nanoemulsion Enhances Photodynamic Therapy against Multi-species Biofilms related to Periodontitis

Gabriel Garcia de Carvalho¹, Patricia Milagros Maquera Huacho¹, Julio Cesar Sánchez-Puetate², Kleber Thiago de Oliveira³, Alessandra Nara de Souza Rastelli⁴, Daniela Leal Zandim-Barcelos², Denise Madalena Palomari Spolidorio¹

¹Department of Physiology and Pathology, São Paulo State University (Unesp), School of Dentistry at Araraquara, Araraquara, São Paulo, Brazil.; ²Department of Oral Diagnosis and Surgery, São Paulo State University (Unesp), School of Dentistry at Araraquara, Araraquara, São Paulo, Brazil.; ³Department of Chemistry, Federal University of São Carlos (UFSCar), São Carlos, São Paulo, Brazil; ⁴Department of Restorative Dentistry, School of Dentistry, São Paulo State University (Unesp School of Dentistry at Araraquara, Araraquara, São Paulo, Brazil.

Bromine Indirubin PLIM sensors to measure oxygen in normoxic and hypoxic PDT conditions

Daniela Nobre Sarmento dos Santos^1,2, Nilanjon Naskar¹, Estefania Delgado-Pinar^2,3, João Sérgio Seixas de Melo², Angelika Rueck¹

¹Core Facility for Confocal and Multiphoton Microscopy, University of Ulm, Germany; ²Coimbra Chemistry Center , University of Coimbra, Portugal; ³University of Valencia, Institute of Molecular Science, Department of Chemistry, Spain.

Inflammatory linear verrucous epidermal nevus successfully treated with 5-aminolevulinic acid photodynamic therapy in 4-year-old children

Bingyu Xiu, Xu Li, Li Wei, Mutong Zhao, Lin Ma

Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China

Investigating the effects of a temperature dependent photodynamic dose: a numerical study

Andrew Effat^1,2, Nicholas Bernards², Runjie Bill Shi¹, Gang Zheng^1,3,4, Brian Wilson^3,4, Robert Weersink^1,3,4, Kazuhiro Yasufuku^1,2,3

¹Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.; ²Division of Thoracic Surgery, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.; ³Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; ⁴Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

Cost-effective device for theranostics of superficial tumors with fluorescence quantification and indirect PDT efficacy dosimetry.

Maxim Loshchenov¹, Andrey Udeneev¹, Nina Kalyagina^1,2, Arina Plotnikova⁴, Artem Shiryaev³

¹National Research Nuclear University MEPhI, Russian Federation; ²Prokhorov General Physics Institute of the Russian Academy of Sciences, Russian Federation; ³L.L. Levshin Institute of Cluster Oncology, University Clinical Hospital №1 I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation; ⁴volunteering student

First results of photochemotherapy as an induction treatment in patients with HPV-negative squamous cell carcinoma of the head and neck.

Alena Mamedova, Artem Shiryaev, Kanamat Efendiev, Igor Reshetov, Аndrey Udeneev, Kulichenko A.M., Loshchenov Maxim, Kulikov Timur, Uzunova Serguzana, Agakina Julia, Dudko Julia

Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Department of Oncology, Radiotherapy and Reconstructive Surgery, University Clinical Hospital No.1, Bolshaya Pirogovskaya Str., 6, Moscow, Russian Federation