Methylene blue photodynamic therapy of deep tissue abscesses: Phase 1 clinical trial and optical spectroscopy results

Timothy Baran, Md Nafiz Hannan, Laurie Christensen, Erica Longbine, Thomas Foster, Ashwani Sharma

University of Rochester, United States of America

Studying the effect of photosensitizer heterogeneity and its spatial extent on personalized iPDT treatment planning solution

Tina Saeidi¹, Shuran Wang², Hectoralex Contreras¹, Stefanie Markevich³, Josephine La Macchia³, Michael J Daly³, Vaughan Betz², Lothar Lilge¹

¹Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre, University 8 Health Network, 101 College Street, Toronto, ON M5G1L7, Canada; ²Edward S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, 10 6 King’s College Rd, Toronto, ON M5S3G8, Canada; ³TECHNA, University 8 Health Network, 101 College Street, Toronto, ON M5G1L7, Canada

Correlation of in Vitro Cell Viability and Cumulative Singlet Oxygen Luminescence from Protoporphyrin IX in Mitochondria and Plasma Membrane

Buhong Li¹, Yi Shen², Huiyun Lin², Brian C. Wilson³

¹Hainan University, People's Republic of China; ²Fujian Normal University, People's Republic of China; ³University of Toronto, Canada

Predicting spatially resolved photosensitizer distribution based on its partition coefficient and extravasation rate for personalized iPDT treatment planning

Tina Saeidi, Nader Allam, Timothy Samuel, Alex Vitkin, Ralph S DaCosta, Lothar Lilge

Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre, University Health Network, 101 College Street, Toronto, ON M5G1L7, Canada

Development of a two-photon fluorescent nanoprobe for intracellular detection and quantification of nitric oxide

Carla Arnau del Valle^1,2, Paul Thomas³, Francisco Galindo⁴, Maria Paz Muñoz Herranz^1,5, Maria Jose Marín¹

¹School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, United Kingdom; ²Fischell Department of Bioengineering, University of Maryland, College Park, Maryland, United States.; ³School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, United Kingdom; ⁴Departamento de Química Inorgánica y Orgánica, Universitat Jaume I, Castellón, Spain; ⁵Department of Chemistry, Lancaster University, Bailrigg, Lancaster, United Kingdom

Real-Time monitoring of Photodynamic Therapy with Ultrasound guided Photoacoustic Imaging

Andrew Langley, Faizah Wulandana, Brian Li, Daniel Wong, Marvin Xavierselvan, Srivalleesha Mallidi

Tufts University, United States of America

Combined investigation on changes in MRI relaxation times and optical properties of porcine tissue and artificial tissue phantoms

Maximilian Aumiller^1,2, Asmerom Arazar¹, Olaf Dietrich³, Ronald Sroka^1,2, Adrian Rühm^1,2

¹Laser-Forschungslabor, LIFE-Zentrum, University Hospital, LMU Munich, Germany; ²Department of Urology, University Hospital, LMU Munich, Germany; ³Department of Radiology, University Hospital, LMU Munich, Germany

Multispectral singlet oxygen luminescent dosimetry (MSOLD) for Photofrin-mediated PDT

Timothy C Zhu¹, Weibing Yang¹, Hongjing Sun¹, Robert H Hadfield², Brian C Wilson³

¹University of Pennsylvania, United States of America; ²University of Glasgow, United Kingdom; ³University of Toronto, Canada