Session Chair: Sanjay Mathur, University of Cologne
1:30pm - 2:00pm Invited
Bio-molecule Tagged Polymer Wrapped Single Walled Carbon Nanotubes (SWNTs): Promises and Prospects
Minaketan TRIPATHY1, Abubakar ABDUL MAJEED1, Ravindrachary VASACHAR2, Sunil KUMAR3
1Universiti Teknologi MARA, Malaysia; 2Mangalore University, India; 3Indian Council of Agricultural Research (ICAR)-National Bureau of Agriculturally Important Microorganisms (NBAIM), India
Single wall carbon nanotubes (SWNTs) have received the attention of the scientific community owing to their versatile character and diverse applications. SWNTs have been investigated in many fields of scientific interest. Though the molecule has demonstrated many capabilities, it suffers in regard to its physicochemical character of poor aqueous solubility because of its super hydrophobicity, which is very important in regard to the areas involving pharmaceutical life sciences. There are several reports by our laboratory regarding non covalent functionalization of SWNTs by polymer wrapping. Further tagging of specific biomolecules to SWNTS during polymer wrapping is aimed at the enhancement of the targetability of the conjugate for drug delivery. This presentation shall highlight our work on biomolecule tagged polymer wrapped SWNTs, the involved solution chemistry, the probable mechanism of polymer wrapping along with the biomolecule tagging using biophysical and computational methods as the promises, whereas and some present investigations relating the impact in drug delivery, those will guide us to further extend our endeavor in the field of translational research under the theme of prospects.
2:00pm - 2:30pm Invited
Design and Fabrication of Adsorbents with High Active Sites Dispersion by Using Confined Space
State Key laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing Tech University, China
A lot of attempts have been made to promote the dispersion of active species, which is considered an essential factors affecting the performance of adsorbates. Despite great efforts, the development of a facile, efficient method to achieve high dispersion of active species remains a great challenge. Our group has developed a strategy to promote the dispersion of active species by directly using as-synthesized mesoporous silica (typically SBA-15) as support. The confined space between template and silica walls is highly efficient in the dispersion of active species, which vary from metals (Au, Pt, Pd, Rh, etc.) to metal oxides (CuO, CeO2, NiO, etc.). The resultant materials containing highly dispersed active sites are efficient in various applications (e.g. adsorption of olefins and sulfur compounds as well as catalytic reduction). The present strategy permits template removal and precursor conversion in one step (or preservation of template in some cases), avoids the repeated calcination in conventional modification process, and saves time and energy. Moreover, metal-organic polyhedra with a dimension of about 3 nm can be confined in the cavities of mesoporous silica SBA-16. This avoids the aggregation of metal-organic polyhedra that hinders the active sites and improves the adsorption capacity greatly. Our strategy using confined spaces may open up a new way for the design and synthesis of new functional materials with excellent adsorption performance.
2:30pm - 3:00pm Invited
Preparation of Bimetallic Magnetic Nanocrystals by Oxidative Precipitation
Yurena LUENGO1, Maria VARELA2, Maria del Puerto MORALES1, F Javier PALOMARES1, Sabino VEINTEMILLAS-VERDAGUER1
1Instituto de Ciencia de Materiales de Madrid, Consejo Superior de Investigaciones Cientificas (CSIC), Spain; 2Complutense University of Madrid, Spain
In this communication we present a novel route for the preparation of bimetallic nanocrystals based on the oxidative precipitation of magnetite in presence of a second metal such as : Au, Bi, Co, Gd that co-crystallize with magnetite. The nanostructures formed depend on the ionic radii of the doping metal and the relative solubilities of the oxide/hydroxide of the dopant and the magnetite. In this way cobalt is incorporated easily to the magnetite structure as solid solution (Co) but the rest of the metals considered were segregated to the surface forming core-shell nanosestructures (Bi, Gd) or simply associated to the magnetite by dispersion forces (Au). The samples were characterized by chemical analysis, X-ray Photoelectron Spectroscopy (XPS), X-Ray powder diffraction, transmission electron microscopy, electron energy-loss spectroscopy EELS, high angle annular dark field image HAADF. In all cases the composition of the product reproduce the starting composition until the 5% at. The magnetic properties of the magnetite cores were not damaged during the process. The bimetallic nanoparticles could be dispersed and coated in the same way than the pure magnetite nanocrystals to produce stable colloids.The performances of the biomedical applications of these colloids as contrast agents and thermal seeds for magnetothermia will be discussed.