Conference Agenda
Overview and details of the sessions of this conference. Please select a date or location to show only sessions at that day or location. Please select a single session for detailed view (with abstracts and downloads if available).
Poster Size: Posters need to be portrait and no more than A0 size (841mm (w) x 1189 mm (h) or 33.1 inches (w) x 46.8 inches (h)).
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Program Overview |
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Presidential Address: Professor Sheena Josselyn
Dr. Anna Phan (Asst Prof Univ Alberta) will introduce Dr. Sheena Josselyn | ||
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Making memories in mice Hospital for Sick Children Sheena A. Josselyn1,2,3 Understanding how the brain uses information is a fundamental goal of neuroscience. Several human disorders (ranging from autism spectrum disorder to PTSD to Alzheimer’s disease) may stem from disrupted information processing. Therefore, this basic knowledge is not only critical for understanding normal brain function, but also vital for the development of new treatment strategies for these disorders. Memory may be defined as the retention over time of internal representations gained through experience, and the capacity to reconstruct these representations at later times. Long-lasting physical brain changes (‘engrams’) are thought to encode these internal representations. The concept of a physical memory trace likely originated in ancient Greece, although it wasn’t until 1904 that Richard Semon first coined the term ‘engram’. Despite its long history, finding a specific engram has been challenging, likely because an engram is encoded at multiple levels (epigenetic, synaptic, cell assembly). My lab is interested in understanding how specific neurons are recruited or allocated to an engram, and how neuronal membership in an engram may change over time or with new experience. Here I will describe data in our efforts to understand memories in mice. 1Program in Neurosciences & Mental Health, Hospital for Sick Children, 555 University Ave. Toronto, ON, M5G 1X8, Canada. 2Dept. of Physiology, University of Toronto, Toronto, ON, M5G 1X8, Canada. 3Dept. of Psychology, University of Toronto, Toronto, ON, M5G 1X8, Canada. | ||
