Conference Agenda

Lost (and found) in latent land: applications to weather and climate

Pierre Gentine

Columbia University, United States of America

Embracing the Tyranny of Testing

Moritz Hardt

Max Planck Institute for Intelligent Systems, Germany

Bridging Perception and Logic: An Abductive Learning Cycle for Semantically Anchored Facial Expression Recognition

Jens Johannes Gebele^1,2, Philipp Brune¹, Frank Schwab², Sebastian von Mammen²

1: Neu-Ulm University of Applied Sciences, Germany; 2: University of Würzburg

Human-in-the-loop Concept Discovery and Curation in Vision Foundation Models

Hyesu Lim¹, Jinho Choi², Jaegul Choo², Steffen Schneider¹

1: Helmholtz Munich, Germany; 2: KAIST AI, South Korea

TACTIC: Tabular-Attribute Conditioned Transformer for Image Classification

Laura Daza^1,2, Marta Hasny^1,2, Cristina González^1,2, Julia Schnabel^1,2,3

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: King's College London, UK

Learning Physical Geometry from Noisy Helical Particle Tracks: A Comparative Study of Transformers, SBI, and JEPA

Sylvain Caillou, Jan Stark, Alexis Vallier, Catherine Biscarat

L2I Toulouse, CNRS/IN2P3, Université de Toulouse

Learning Actionable Insights from Scientific Data

Jilles Vreeken

CISPA Helmholtz Center for Information Security, Germany

RIBEX: Predicting and Explaining RNA Binding Across Structured and Intrinsically Disordered Regions (IDR)-rich Proteins

Samuele Firmani^1,2, Felix Steinbauer^2,4, Gjergji Kasneci^2,3,4, Annalisa Marsico¹, Marc Horlacher^1,2

1: Helmholtz Munich, Germany; 2: School of Computation, Information and Technology, TUM; 3: School of Social Sciences and Technology, TUM; 4: Munich Center for Machine Learning (MCML)

FoldSAE: Learning to Steer Protein Folding Through Sparse Representations

Wojciech Zarzecki^1,2,4, Paulina Szymczak³, Ewa Szczurek^1,3, Kamil Deja^2,4

1: University of Warsaw, Poland; 2: Warsaw University of Technology, Poland; 3: Helmholtz Munich, Germany; 4: Ideas Research Institute

Interpreting Multimodal Latent Spaces in Single-Cell Multi-omics with Feature Attribution Techniques

Anis Ismail, Alejandro Sifrim

Laboratory of Multi-omics Integrative Bioinformatics, Department of Human Genetics, KU Leuven, Leuven, Belgium.

Structured and interpretable patient embeddings from Single-Cell Foundation Models

Gonçalo Pinto

Helmholtz Munich, Germany

MLflow pilot service for Helmholtz researchers

Lisana Berberi, Christophe Laures, Khadijeh Alibabaei, Valentin Kozlov, Achim Streit

Karlsruhe Institute of Technology (KIT), Germany

Towards Robust Foundation Models for Digital Pathology

Jonah Kömen^1,2, Edwin de Jong³, Julius Hense^1,2, Hannah Marienwald^1,2, Jonas Dippel^1,2,3, Philip Naumann^1,2, Eric Marcus⁴, Lukas Ruff³, Maximilian Alber^3,7, Jonas Teuwen⁴, Frederick Klauschen^1,5,6,7, Klaus-Robert Müller^1,2,8,9

1: Berlin Institute for the Foundations of Learning and Data (BIFOLD), Berlin, Germany; 2: Machine Learning Group, Technische Universität Berlin, Berlin, Germany; 3: Aignostics, Berlin, Germany; 4: The Netherlands Cancer Institute Amsterdam (NKI), Antoni van Leeuwenhoek Hospital (AvL), Amsterdam, Netherlands; 5: Institute of Pathology, Ludwig Maximilian University, Munich, Germany; 6: German Cancer Research Center, Heidelberg, and German Cancer Consortium, Munich, Germany; 7: Institute of Pathology, Charité Universitätsmedizin, Berlin, Germany; 8: Department of Artificial Intelligence, Korea University, Seoul, Korea; 9: Max-Planck Institute for Informatics, Saarbrücken, Germany

Sailing Past Syntax: A Human-in-the-Loop Framework for Safe Generative AI in Science

Nico Schuster

Centre de Physique des Particules de Marseille, France

The Helmholtz Model Zoo: Enabling AI Model Sharing and Inference in the Helmholtz Cloud

Hans Werners, Engin Eren, Philipp Heuser

Deutsches Elektronen-Synchroton DESY, Germany

Improving Reliability of LLM-Based Robotic Task Planning Through Domain Adaptation and Benchmarking

Kanak Pandit, Ananya Kulkarni, Muhammad Saeed

ARENA2036, Germany

Modelling Urban Air Pollution with a Transferable Probabilistic Machine Learning Approach

Martin Ramacher¹, Paul Keil^1,2, Tobias Weigel^1,2

1: Helmholtz Zentrum Hereon, Germany; 2: Helmholtz AI

Uncertainty-Guided Generation of Dark-Field Radiographs

Lina Felsner^1,2,3, Henriette Bast^4,5,6, Tina Dorosti^4,5,6, Florian Schaff^4,5,6, Franz Pfeiffer^4,5,6,7, Daniela Pfeiffer^5,6,7, Julia Schnabel^1,2,3,8

1: School of Computation, Information and Technology, Technical University of Munich, 85748 Garching, Germany; 2: Munich Center for Machine Learning (MCML), Munich, Germany; 3: Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich, 85764 Neuherberg, Germany; 4: Department of Physics, School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany; 5: Munich Institute of Biomedical Engineering, Technical University of Munich, 85748 Garching, Germany; 6: Institute for Diagnostic and Interventional Radiology, School of Medicine and Health, TUM University Hospital Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany; 7: Institute for Advanced Study, Technical University of Munich, 85748 Garching, Germany; 8: School of Biomedical Engineering & Imaging Sciences, King’s College, London, UK

AI-assisted Classification of Polar Phytoplankton’s Functional Biodiversity using Multispectral Imaging Flow Cytometry

Natasha Bryan¹, Anna Naberhaus¹, Sarah Lena Eggers¹, Antonia Thielecke¹, Mar Fernandez Mendez^1,2

1: Alfred Wegener Institute, Germany; 2: University of Bremen, Germany

SoraCT: Unconditioned 3D CT Synthesis via Video Diffusion Transformers

Jiayi Wang¹, Hadrien Reynaud¹, Bernhard Kainz^1,2

1: Friedrich-Alexander University Erlangen-Nürnberg, Germany; 2: Department of Computing, Imperial College London, UK

A 3D Foundation Model for Generalizable Biological Structure Segmentation in Tissue Clearing Images

Qi Liu^1,3,4,5, Ying Chen^1,3,4,5, Markus Elsner^1,6, Ali Ertürk^1,2,4,6,7

1: Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians University Munich, Munich, Germany; 2: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany; 3: Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany; 4: Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; 5: Munich Medical Research School (MMRS), Munich, Germany; 6: Deep Piction GmbH, Munich, Germany; 7: School of Medicine, Koç University, İstanbul, Turkey

Interpretable Representations for Hematology

Muhammed Furkan Dasdelen¹, Hyesu Lim¹, Paul Pommer¹, Michele Buck², Steffen Schneider¹, Carsten Marr¹

1: Helmholtz Munich, Germany; 2: Medical Department for Hematology and Oncology, Technical University Munich

Analysis of multi-omics data using graph neural networks identifies novel schizophrenia-associated genes suitable as drug targets

Svitlana Oleshko^1,2, Samuele Firmani¹, Jamie Robinson², Julien Hernandez-Lallement², Sergio Picart-Armada², Matthias Heinig¹, Till F.M. Andlauer^2,3, Annalisa Marsico²

1: Helmholtz Munich, Germany; 2: Boehringer Ingelheim Pharma, Germany; 3: Technical University of Munich, Germany

MLflow pilot service for Helmholtz researchers

Lisana Berberi, Christophe Laures, Khadijeh Alibabaei, Valentin Kozlov, Achim Streit

Karlsruhe Institute of Technology (KIT), Germany

Towards Robust Foundation Models for Digital Pathology

Jonah Kömen^1,2, Edwin de Jong³, Julius Hense^1,2, Hannah Marienwald^1,2, Jonas Dippel^1,2,3, Philip Naumann^1,2, Eric Marcus⁴, Lukas Ruff³, Maximilian Alber^3,7, Jonas Teuwen⁴, Frederick Klauschen^1,5,6,7, Klaus-Robert Müller^1,2,8,9

1: Berlin Institute for the Foundations of Learning and Data (BIFOLD), Berlin, Germany; 2: Machine Learning Group, Technische Universität Berlin, Berlin, Germany; 3: Aignostics, Berlin, Germany; 4: The Netherlands Cancer Institute Amsterdam (NKI), Antoni van Leeuwenhoek Hospital (AvL), Amsterdam, Netherlands; 5: Institute of Pathology, Ludwig Maximilian University, Munich, Germany; 6: German Cancer Research Center, Heidelberg, and German Cancer Consortium, Munich, Germany; 7: Institute of Pathology, Charité Universitätsmedizin, Berlin, Germany; 8: Department of Artificial Intelligence, Korea University, Seoul, Korea; 9: Max-Planck Institute for Informatics, Saarbrücken, Germany

Sailing Past Syntax: A Human-in-the-Loop Framework for Safe Generative AI in Science

Nico Schuster

Centre de Physique des Particules de Marseille, France

The Helmholtz Model Zoo: Enabling AI Model Sharing and Inference in the Helmholtz Cloud

Hans Werners, Engin Eren, Philipp Heuser

Deutsches Elektronen-Synchroton DESY, Germany

Improving Reliability of LLM-Based Robotic Task Planning Through Domain Adaptation and Benchmarking

Kanak Pandit, Ananya Kulkarni, Muhammad Saeed

ARENA2036, Germany

Modelling Urban Air Pollution with a Transferable Probabilistic Machine Learning Approach

Martin Ramacher¹, Paul Keil^1,2, Tobias Weigel^1,2

1: Helmholtz Zentrum Hereon, Germany; 2: Helmholtz AI

Uncertainty-Guided Generation of Dark-Field Radiographs

Lina Felsner^1,2,3, Henriette Bast^4,5,6, Tina Dorosti^4,5,6, Florian Schaff^4,5,6, Franz Pfeiffer^4,5,6,7, Daniela Pfeiffer^5,6,7, Julia Schnabel^1,2,3,8

1: School of Computation, Information and Technology, Technical University of Munich, 85748 Garching, Germany; 2: Munich Center for Machine Learning (MCML), Munich, Germany; 3: Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich, 85764 Neuherberg, Germany; 4: Department of Physics, School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany; 5: Munich Institute of Biomedical Engineering, Technical University of Munich, 85748 Garching, Germany; 6: Institute for Diagnostic and Interventional Radiology, School of Medicine and Health, TUM University Hospital Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany; 7: Institute for Advanced Study, Technical University of Munich, 85748 Garching, Germany; 8: School of Biomedical Engineering & Imaging Sciences, King’s College, London, UK

SoraCT: Unconditioned 3D CT Synthesis via Video Diffusion Transformers

Jiayi Wang¹, Hadrien Reynaud¹, Bernhard Kainz^1,2

1: Friedrich-Alexander University Erlangen-Nürnberg, Germany; 2: Department of Computing, Imperial College London, UK

A 3D Foundation Model for Generalizable Biological Structure Segmentation in Tissue Clearing Images

Qi Liu^1,3,4,5, Ying Chen^1,3,4,5, Markus Elsner^1,6, Ali Ertürk^1,2,4,6,7

1: Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians University Munich, Munich, Germany; 2: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany; 3: Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany; 4: Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; 5: Munich Medical Research School (MMRS), Munich, Germany; 6: Deep Piction GmbH, Munich, Germany; 7: School of Medicine, Koç University, İstanbul, Turkey

M²S³OM-graph: A Hybrid Deterministic-LLM Pipeline for Automated Metadata Crosswalk Extraction and Graph-Grounded Interoperability

Santiago Casas Castro

Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR), Germany

EO Foundation Models for Pre-Training Dataset Uncertainty Analysis

Stefan Dan, Jakob Gawlikowski

German Aerospace Center, Remote Sensing Technology Institute, Germany

FrustrAI-Seq: Scaling Local Energetic Frustration to the Protein Sequence Space

Jan-Philipp Leusch^1,2, Miriam Poley-Gil³, Miguel Fernandez-Martin³, Nicola Bordin⁴, Burkhard Rost², R. Gonzalo Parra³, Michael Heinzinger^1,2

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: Barcelona Supercomputing Center, Spain; 4: University College London, United Kingdom

muBRAND: Multi-Branch Diffusion for Flexible Generation and Inpainting of Image Series

Jan-Oliver Kropp^1,2,3, Katrin Amunts^1,3, Timo Dickscheid^1,2,4, Christian Schiffer^1,2

1: Forschungszentrum Jülich, Germany; 2: Helmholtz AI, Jülich, Germany; 3: C. und O. Vogt Insitut, Universitätsklinikum Düsseldorf, Düsseldorf, Germany; 4: Institute of Computational Visualistics, Koblenz University, Koblenz, Germany

Multimodal Analysis of Organoid Network Dynamics Using Multielectrode Arrays and Calcium Imaging

Katrina Ager, Silviu Vasile-Bodea, Lucas Mair, Gil Westmeyer, Steffen Schneider

Helmholtz Munich, Germany

Towards Multimodal Inference of Electron Bunch Structures using Gradient-Based Reconstruction with Differentiable Detector Models

Ritz Ann Aguilar¹, Maxwell LaBerge¹, Alexander Debus¹, Andreas Doepp², Zewu Bi^2,3, Michael Bussmann^1,4, Arie Irman¹, Ulrich Schramm^1,5, Jeffrey Kelling^1,6

1: Helmholtz-Zentrum Dresden-Rossendorf, Germany; 2: Ludwig-Maximilians-Universität München, Germany; 3: Shanghai Jiao Tong University, China; 4: Center for Advanced Systems Understanding, Germany; 5: Technische Universität Dresden, Germany; 6: Technische Universität Chemitz, Germany

NURBSeg: bridging the gap between Mmdical imaging and CAD via end-to-end parametric segmentation

Hakan Akdag¹, Philipp Rosauer¹, Sebastian Ziegler², Kris Dreher², Alexander Rüttgers¹

1: German Aerospace Center (DLR), Germany; 2: German Cancer Research Center (DKFZ), Germany

From prediction to generation of antigen-specific, full-length T-cell receptors

Yang An^1,2, Felix Drost^1,2, Adrian Straub², Kersten Heyer², Annalisa Marsico¹, Dirk H. Busch², Benjamin Schubert¹

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany

Provenance-Aware Knowledge Graphs for Reusable PEFC and PEWE Experiments

Ezgi Arat^1,2,3, Andreas Glüsen¹, Martin Florian Seidler¹, Mohammad Javad Eslamibidgoli², Michael Eikerling^2,3, Kourosh Malek², Paul Kieckhefen^4,5

1: Institute of Energy Technologies (IET-4), Electrochemical Process Engineering, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany; 2: Theory and Computation of Energy Materials (IET-3), Institute of Energy Technologies, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany; 3: Chair for Theory and Computation of Energy Materials, Faculty of Georesources and Materials Engineering, RWTH Aachen University, 52062 Aachen, Germany; 4: Data Analytics, Access and Applications, Scientific Computing Center (SCC), Karlsruher Institut für Technologie, 76344 Eggenstein-Leopoldshafen, Germany; 5: Helmholtz AI, Karlsruher Institut für Technologie, 76344 Eggenstein-Leopoldshafen, Germany

Deep Learning Modeling of RNA Structure Perturbations Induced by Small Molecules

Tobias Bernecker^1,2, Lambert Moyon¹, Danny Incarnato^3,4, Annalisa Marsico^1,4

1: Computational Health Center, Helmholtz Munich, Munich, Germany; 2: School of Computation, Information and Technology, Technical University of Munich, Munich, Germany; 3: Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands; 4: Equal contributions

T-time: Multimodal Manifold Learning for Clonally Constrained Trajectory Inference

Irene Bonafonte Pardàs¹, Myriam Lizotte^2,3, Guy Wolf^2,3, Benjamin Schubert¹

1: Helmholtz Munich, Germany; 2: Mila – Quebec AI Institute, Montréal, Canada; 3: Department of Mathematics and Statistics, Université de Montréal

End-To-End Protein Engineering With Protein Language Models

Maurice Brenner^1,2, Helene Wetekam^1,2, Alexander Plaikner², Manuel Ploner², Robert Schmirler², Burkhard Rost², Michael Heinzinger^1,2

1: Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Germany; 2: Department of Bioinformatics and Computational Biology , Technical University of Munich, Germany

AI-assisted Labeling and its Pitfalls: A Case Study in Electron Microscopy Segmentation

Christina Bukas¹, Jonas Engler², Helena Pelin¹, Jonas Hagenberg¹, Haider Khan¹, Francesco Campi¹, Carola Eberhagen³, Hans Zischka^2,3, Marie Piraud¹

1: Helmholtz AI, Helmholtz Center Munich, Germany; 2: Institute of Toxicology and Environmental Hygiene, TUM School of Medicine and Health, Technical University of Munich, Germany; 3: Institute of Molecular Toxicology and Pharmacology, Helmholtz Center Munich, Germany

Spatial and Temporal Evaluation of Extreme Precipitation in ML-Based Global Weather Forecasts

Sebastian Buschow, Wael Almikaeel

Forschungszentrum Jülich, Germany

Recurrent Neural Networks and Tensor Ring Decomposition

Saptarshi Chakrabarti, Nick Vannieuwenhoven

KU Leuven, Belgium

AI and Hierarchical Clustering Techniques for Accurate Patient Stratification

Juan G. Diaz Ochoa², Miroslav Puskaric³, Natalie Layer⁴, Antje Jensch⁴, Markus Knott⁴, Alexander Krohn^1,5

1: Hochschule München, Campus for Health and Engineering, Munich, Germany; 2: PerMediQ, Stuttgart, Germany; 3: University of Stuttgart, HLRS - High Performance Computing Center, Stuttgart, Germany; 4: Klinikum Stuttgart, Stuttgart Cancer Center - Tumorzentrum Eva Mayr-Stihl DE, Stuttgart, Germany; 5: University Hospital Regensburg, Department of Internal Medicine I, Regensburg, Germany

SciTracer - the reliable and logically provable autonomous scientific discovery.

Leonid Didukh

Unaffiliated, Ukraine

Benchmarking for Microscopic Biodiversity Screening (AIMBIS-project)

Susanne Dunker^1,2, Kathleen Stoof-Leichsenring³, Mar Fernández-Méndez⁴, Riccardo Massei^1,2, Jan Bumberger^1,2

1: Helmholtz-Centre for Environmental Research GmbH (UFZ), Germany; 2: German Centre for integrative Biodiversity Research e.V. Halle-Jena-Leipzig (iDiv), Germany; 3: Helmholtz-Centre for Polar and Marine Research – AWI, Department/Section Polar Terrestrial Environmental Systems; 4: Helmholtz-Centre for Polar and Marine Research – AWI, Department/Section Polar Biological Oceanography

MolecuLA: Learning Molecules As A Language For Generative And Interpretable Chemistry

Zakaria Elabid¹, Attila Cangi¹, Jan Andrzejewski^1,2, Bartosz Brzoza^1,2

1: CASUS/Helmholtz-Zentrum Dresden-Rossendorf, Germany; 2: University of Wrocław, Poland

Construct-valid and adaptive benchmarks for single-cell RNA-seq via a hierarchical, streaming simulator

Philipp Flotho^1,2, Matthias Flotho^1,2, Andreas Keller^1,2

1: Chair for Clinical Bioinformatics, Saarland University, Germany; 2: Helmholtz Institute for Pharmaceutical Research Saarland

From T-FAKE to TFAN: Reusable Thermal Face Alignment for AI in Scientific Imaging

Philipp Flotho^1,4,5, Moritz Piening^2,5, Anna Kukleva³, Gabriele Steidl²

1: Chair for Clinical Bioinformatics, Saarland University, Germany; 2: Technical University of Berlin, Germany; 3: MPI for Informatics, SIC, Germany; 4: Helmholtz Institute for Pharmaceutical Research, Germany; 5: Equal author contribution

From Feature Learning to Neural Collapse: A Data-Dependent Kernel View

Pankhil Gawade^1,2, Kirsten Fischer¹, Ewa Szczurek^1,3

1: Helmholtz Munich, Germany; 2: Technical University of Munich, TUM School of Computation, Information and Technology; 3: Faculty of Mathematics, Informatics and Mechanics, University of Warsaw

Sparse Autoencoders are Topic Models

Leander Girrbach^1,2,3, Zeynep Akata^1,2,3

1: Helmholtz Munich; 2: Technical University of Munich; 3: Munich Center for Machine Learning

Do world models model the world?

Rodrigo Gonzalez Laiz

Helmholtz Munich, Germany

Editing the Foundations: Task Arithmetic for 3D Medical Segmentation Foundation Models

Cristina González^1,2, Laura Daza^1,2, Julia Schnabel^1,2,3

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: King's College London, UK

Spatial transcriptomics-informed inference of cell types and states from nuclear-stained whole slide images.

Beatrice Guastella^1,2, Ziqing Zhao^1,2, Martin Dichgans^2,4, Mikael Simons^2,3,4,5, Hannah Spitzer^1,2,4

1: Institute of Computational Biology (ICB), Helmholtz Zentrum München, Munich, Germany; 2: Institute for Stroke and Dementia Research (ISD), Klinikum der Universität München, Munich, Germany; 3: German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; 4: Munich Cluster of Systems Neurology (SyNergy), Munich, Germany; 5: Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany

Uncertainty Quantification for Medical Image Segmentation

Maleeha Hassan, Till Korten, Ulrik Günther, Peter Steinbach

HZDR, Germany

Fast and Few-Shot: Equipping Scientific LLM Agents with Meta-Learned Surrogates

Hamed Hemati¹, Stefan Sandfeld^1,2

1: Institute for Advanced Simulations – Materials Data Science and Informatics (IAS-9), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany; 2: Chair of Materials Data Science and Materials Informatics, Faculty 5 – Georesources and Materials Engineering, RWTH Aachen University, 52056 Aachen, Germany

scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution.

Johannes Hingerl^1,3, Laura D. Martens^1,2, Aleksandr Neverov¹, Mariia Minaeva², Nils F. Wagner¹, Fabian J. Theis^1,2, Julien Gagneur^1,2,3,4

1: Technical University of Munich, School of Computation, Information and Technology, Munich, Germany; 2: Helmholtz Center Munich, Computational Health Center, Neuherberg, Germany; 3: Technical University of Munich, Munich Center for Machine Learning, Munich, Germany; 4: Technical University of Munich, Institute of Human Genetics, School of Medicine, Munich, Germany

Quantifying the Differential Privacy–Fairness Trade-Off Across Intersectional Subgroups in Structured Prediction

Abanoub Ibrahim

Sirr global, Egypt

Geospatial Causal Inference for Drought Driver Analysis

Vytautas Jancauskas, Samuel Garske, Daniela Espinoza-Molina

DLR, Germany

When Protein Dynamics Matter: Integrating Molecular Dynamics into Protein Foundation Models

Reem Aboelsoud, Kasravi Javad, Stefan Kesselheim, Alina Bazarova

jülich forschungszentrum, Germany

Toward Automated MRI-Based Screening of Cortical Superficial Siderosis Using Multimodal 3D nnU-Net

Wasim Aftab¹, Anna Dewenter¹, Maria Kaffe¹, Anna Kopczak¹, Martin Dichgans¹, Hannah Spitzer^1,2

1: Institute for Stroke and Dementia Research(ISD), University Hospital, LMU Munich,Munich, Bavaria, Germany; 2: Institute of Computational Biology (ICB), Helmholtz Munich, Neuherberg, Germany

Cross-View Latent Integration via Nonparametric Gamma Shrinkage Factor Analysis

Hassan Akell¹, Małgorzata Łazęcka², Dinesh A Haridoss¹, Miriam Urban³, Eike Staub³, Ewa Szczurek^1,2

1: Institute of AI for Health, Helmholtz Munich; 2: Faculty of Mathematics, Informatics and Mechanics, University of Warsaw; 3: Oncology Data Science, Merck Healthcare KGaA

Physics-Guided Diffusion for Neonatal Ultra-Low-Field MRI enhancement

Malek Al Abed^1,3, Sebiha Demir², Anne Groteklaes², Elodie Germani⁴, Shahrooz Faghihroohi³, Hemmen Sabir², Shadi Albarqouni^1,3

1: University of Bonn, University Hospital Bonn, Clinic for Diagnostic and Interventional Radiology, Germany; 2: University of Bonn, University Hospital Bonn, Department of Experimental Neonatology, Germany; 3: Technical University of Munich, School of Computation, Information and Technology, Germany; 4: Laboratoire Traitement du Signal et de l’Image, Inserm UMR 1099, Universit´ e de Rennes, France

Atlas 2 - Foundation Models for Clinical Deployment

Maximilian Alber^1,13, Timo Milbich¹, Alexandra Carpen-Amarie¹, Stephan Tietz¹, Jonas Dippel^1,7,8, Lukas Muttenthaler^1,15,16, Beatriz Perez Cancer¹, Alessandro Benetti¹, Panos Korfiatis³, Elias Eulig¹, Jérôme Lüscher¹, Jiasen Wu¹, Sayed Abid Hashimi¹, Gabriel Dernbach^1,8,13, Simon Schallenberg¹³, Neelay Shah¹, Moritz Krügener¹, Aniruddh Jammoria¹, Jake Matras⁵, Patrick Duffy⁶, Matt Redlon⁴, Philipp Jurmeister^11,12, David Horst^11,13, Lukas Ruff¹, Klaus-Robert Müller^7,8,9,10, Frederick Klauschen^12,13,14, Andrew Norgan²

1: Aignostics, Germany; 2: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, US; 3: Department of Radiology, Mayo Clinic, Rochester MN, US; 4: Department of Information Technology, Mayo Clinic, Rochester MN, US; 5: Mayo Clinic, Rochester MN, US; 6: Digital Pathology, Mayo Clinic, Rochester MN, US; 7: Machine Learning Group, Technische Universität Berlin, Germany; 8: BIFOLD – Berlin Institute for the Foundations of Learning and Data, Germany; 9: Department of Artificial Intelligence, Korea University, Republic of Korea; 10: Max-Planck Institute for Informatics, Germany; 11: German Cancer Research Center (DKFZ) & German Cancer Consortium (DKTK), Berlin & Munich Partner Sites, Germany; 12: Institute of Pathology, Ludwig-Maximilians-Universität München, Germany; 13: Institute of Pathology, Charité – Universitätsmedizin Berlin, Germany; 14: Bavarian Cancer Research Center (BZKF), Germany; 15: Helmholtz Munich, Germany; 16: Technical University Munich, Germany

EOSC-ARENA: Towards an Open and Ethical GenAI Infrastructure for European Research

Khadijeh Alibabaei¹, Lisana Berberi¹, Valentin Kozlov¹, Alexandra Delipalta², Álvaro López García³, Germán Moltó⁴, Fotis Psomopoulos⁵, Viet Tran⁶, Marcin Plociennik⁷

1: Scientific Computing Center (SCC), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, 76344,Germany; 2: Research Data Alliance Association - RAD, Belgium; 3: Instituto de Física de Cantabria (IFCA), CSIC-UC, Avda. los Castros s/n, Santander, 39006, Cantabria, Spain; 4: Instituto de Instrumentación para Imagen Molecular (I3M), Centro Mixto CSIC — Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, España; 5: Ethniko Kentro Erevanas Kai Technologikis Anaptyxis - CERTH, Greece; 6: nstitute of Informatics, Slovak Academy of Sciences (IISAS), Dúbravská cesta 9, Bratislava, 84507, Slovakia; 7: Instytut Chemii Bioorganicznej Polskiej Akademii Nauk - PSNC, Poland

Multimodal graph-based fusion learning for Alzheimer’s disease prediction

Shubhi Ambast^1,2, Karola Mai^1,2, Charles Mwangi Kaumbutha^1,2, Jannis Spintge², Caterina Carraro^2,4, Marc Beyer^2,3, Matthias Becker^1,2

1: Modular High-Performance Computing and Artificial Intelligence, German Center for Neurodegenerative Diseases (DZNE), Bonn, North Rhine-Westphalia, Germany; 2: Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, North Rhine-Westphalia, Germany; 3: PRECISE Platform for Genomics and Epigenomics at DZNE and University of Bonn, Bonn, North Rhine-Westphalia, Germany; 4: Life and Medical Sciences (LIMES) Institute, Genomics & Immunoregulation, Bonn, North Rhine-Westphalia, Germany

Can Large Language Models Grade Short Free-Text Exam Answers? An Evaluation on Real German Student Data

Zeynep Arslan, Lennart Bressel, Fritz Niesel

Forschungszentrum Jülich, Germany

Pseudo-Anomaly Augmented One-Class Autoencoder and Supervised Deep Learning for Murine ECG Anomaly Detection

Marcella Astrid¹, Ewan Selkirk², Christopher S. Ward³, Donatella Cea¹, Christina Bukas¹, Elida Schneltzer⁴, Marie Piraud¹, Nadine Spielmann⁴

1: Helmholtz AI, Helmholtz Center Munich, Germany; 2: Mary Lyon Centre at MRC Harwell, Harwell Campus, United Kingdom; 3: Integrative Physiology/Advanced Technology Cores, Baylor College of Medicine, Texas, United States; 4: Institute of Experimental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health, Germany

A Physics-Based Machine Learning Workflow for Urban-Scale Residential Heat-Demand Estimation

Nazanin Bagherinejad, V Mithlesh Kumar, Julia Kowalski

Chair of Methods for Model-based Development in Computational Engineering, RWTH Aachen University, Germany

scDigital-Karyotypes: a genomic representation to learn shared variants

Suharto Banerjee¹, Elisabeth Georgii², Lisa Barros de Andrade e Sousa², Mai Abdelhalim Mohamed³, Karen Lopez-Cayuqueo³, Kai M. Schmidt-Ott³, Ashley D. Sanders^1,4

1: Max Delbrück Center for Molecular Medicine, Berlin, Germany; 2: Helmholtz AI, Helmholtz Munich, Germany; 3: Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany; 4: Charité – Universitätsmedizin Berlin, Germany

Semi-Supervised Federated Learning for Medical Image Classification

Ayse Edanur Baser

Ozyegin University, Turkey (Türkiye)

ECG Template-Based Deep Learning for Amplified P-wave Duration Prediction

Silvia Becker^1,2, Ajay Krishna², Heiko Lehrmann², Amir Jadidi³, Till Keller^2,4, Dirk Westermann², Thomas Arentz², Axel Loewe¹, Martin Eichenlaub²

1: Karlsruhe Institute of Technology, Germany; 2: University Heart Center Freiburg - Bad Krozingen, Germany; 3: Lucerne Cantonal Hospital, Switzerland; 4: Justus Liebig University Giessen, Germany

Reduction of Outflow Boundary Influence on Aerodynamic Performance Using Neural Networks

Mario Christopher Bedrunka^1,2,3,4, Dirk Reith^4,5, Holger Foysi³, Łukasz Łaniewski-Wołłk⁶, Travis Mitchell²

1: Jülich Supercomputing Centre (JSC), Forschungszentrum Jülich, Wilhelm-Johnen-Straße 52428 Jülich, Germany; 2: School of Mechanical and Mining Engineering, The University of Queensland, St Lucia 4072, Queensland, Australia; 3: Chair of Fluid Mechanics, University of Siegen, Paul-Bonatz-Straße 9-11, Siegen-Weidenau 57076, Germany; 4: Institute of Technology, Resource and Energy-efficient Engineering (TREE), Bonn-Rhein-Sieg University of Applied Sciences, Grantham-Allee 20, Sankt Augustin 53757, Germany; 5: Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, Sankt Augustin 53754, Germany; 6: Institute of Aeronautics and Applied Mechanics, Warsaw University of Technology, Nowowiejska 24, Warszawa 00-665, Poland

Rolv.io - Multi-Agent AI For Healthcare And Research

Alexander Blume¹, Deniz Aydoğdu^1,2, Yoga Mithra Senthil Kumar¹, Nelli Khachatryan¹, Ahmed Tijani Akinfalabi¹, Arash Sorooshmehr¹, Ricardo Wurmus¹, Altuna Akalin¹

1: Max Delbrück Center (MDC), Germany; 2: Hacettepe University, Turkey

Understanding Green Technology Adoption in Germany: A Cluster-Based Analysis of Household-Scale Photovoltaics and Battery Electric Vehicles

Philipp C. Böttcher¹, Leo Kaindl², Lisa Barros de Andrade e Sousa², Marie Piraud², Sandra Venghaus^3,4, Dirk Witthaut^1,5

1: Institute of Climate and Energy Systems: Energy Systems Engineering (ICE-1), Forschungszentrum Jülich, Germany; 2: Helmholtz AI, Helmholtz Munich, Germany; 3: Institute of Climate and Energy Systems: Jülich Systems Analysis (ICE-2), Forschungszentrum Jülich, Germany; 4: School of Business and Economics, RWTH Aachen University, Germany; 5: Institute for Theoretical Physics, University of Cologne, Germany

From Learned Representation To Localization: Towards Semantic Integration Of Microscopic Data In The Human Brain

Zeynep Boztoprak^1,2, Katrin Amunts^1,4, Markus Axer^1,5, Timo Dickscheid^1,2,3, Christian Schiffer^1,2

1: Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Germany; 2: Helmholtz AI, Research Centre Jülich, Germany; 3: Computer Vision, Institute for Computational Visualistics, University of Koblenz, Germany; 4: C. & O. Vogt Institute of Brain Research, University Hospital Düsseldorf, Germany; 5: Department of Physics, University of Wuppertal, Germany

AI-assisted Classification of Polar Phytoplankton’s Functional Biodiversity using Multispectral Imaging Flow Cytometry

Natasha Bryan¹, Anna Naberhaus¹, Sarah Lena Eggers¹, Antonia Thielecke¹, Mar Fernandez Mendez^1,2

1: Alfred Wegener Institute, Germany; 2: University of Bremen, Germany

Beyond Structural Symmetries: Linear Mode Connectivity via Neuron Identifiability

Vincent Bürgin¹, Daniel Herbst¹, Ya-Wei Lin¹, Stefanie Jegelka^1,2

1: Technical University of Munich, Germany; 2: Massachusetts Institute of Technology, United States

PFAD Not Taken: Measuring Polysemanticity in Vision Models via Functional Decomposability in Riemannian Vision-Language Geometry

Kirill Bykov^1,4, Maria Bravo^3,4, Laura Kopf^2,5, Zeynep Akata^1,3,4

1: TU Munich, Germany; 2: TU Berlin, Germany; 3: Helmholtz Munich, Germany; 4: MCML, Germany; 5: BIFOLD, Germany

LEVERAGING MULTI-RATER ANNOTATIONS TO CALIBRATE OBJECT DETECTORS IN MICROSOPY IMAGING

Francesco Campi, Marie Piraud

Helmholtz AI, Helmholtz Zentrum Muenchen, Germany

CytoDiff: AI-Driven Cytomorphology Image Synthesis for Medical Diagnostics

Jan Carreras Boada, Rao Muhammad Umer, Carsten Marr

Helmholtz Munich, Germany

DeepElbe: Multi-Horizon Oxygen Forecasting and Hypoxia Early Warning Using Statistical and Deep Learning Methods

Danu Caus, Ovidio Fernando Garcia Oliva, Carsten Lemmen, Tobias Weigel

Helmholtz-Zentrum Hereon, Germany

Cancer-label-free Tumor Segmentation in Whole-mouse Light Sheet Microscopy Images Using Vision-language Models

Ying Chen^1,3,4,5, Eva Küsters^2,6, Jie Zhang^1,3,4,5, Markus Elsner^2,7, Ali Ertürk^1,2,4,7,8

1: Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians University Munich, Munich, Germany; 2: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany; 3: Faculty of Medicine, Ludwig-Maximilians University Munich, Munich, Germany; 4: Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; 5: Munich Medical Research School (MMRS), Munich, Germany; 6: Graduate School of Neuroscience (GSN), Munich, Germany; 7: Deep Piction GmbH, Munich, Germany; 8: School of Medicine, Koç University, İstanbul, Turkey

Physics-Informed Reconstruction of Electron-Bunch Shapes from CTR Spectra using an Untrained Neural Network

Fabia Dietrich^1,2, Ritz Ann Aguilar¹, Alexander Debus¹, Arie Irman¹, Maxwell LaBerge¹, Richard Pausch¹, Nico Wrobel^1,2, Ulrich Schramm^1,2, Michael Bussmann^1,3, Jeffrey Kelling^1,4

1: Helmholtz-Zentrum Dresden-Rossendorf, Germany; 2: Technische Universität Dresden, Germany; 3: Center for Advanced Systems Understanding, Germany; 4: Technische Universität Chemnitz, Germany

Modeling Long Contexts with Hierarchical Compression Transformers

Eske Ewert, Mario Christopher Bedrunka, Stefan Kesselheim

Forschungszentrum Jülich, Germany

Towards high resolution air quality forecasts for Europe using WGAN-based statistical downscaling with EURAD-IM data

Philipp Franke¹, Sindhu Vasireddy¹, Michael Langguth², Anne Caroline Lange¹, Martin Schultz¹, Anke C. Nölscher¹

1: Forschungszentrum Jülich, Germany; 2: Quarda Energy GmbH, Germany

Data-Driven Identification of Possible Transmission Sites for Carbapenem-Resistant Gram-Negative Bacteria

Elisabeth Georgii¹, Petra Heinmüller², Philipp Thomas², Lisa Barros de Andrade e Sousa¹, Theresa Willem¹, Ivo Foppa², Marie Piraud¹, Anja M. Hauri³

1: Helmholtz AI, Helmholtz Munich, Germany; 2: Hessian State Office for Health and Care (HLfGP), Germany; 3: Helmholtz Centre for Infection Research, Germany

Topological Data Analysis of Single-Cell Multimodal Data

Isabel Giray^1,2, Gabriele Malagoli^1,3, Katharina Schmid¹, Maria Colomé-Tatché^1,3,4

1: Biomedical Center (BMC), Physiological Chemistry, Faculty of Medicine, LMU Munich, Munich, Planegg-Martinsried, Germany; 2: TUM, Germany; 3: Institute of Computational Biology, Computational Health Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; 4: Hospital del Mar Research Institute (HMRIB), Barcelona, Spain

Are Soft Labels Worth the Effort?

Blagovest Gospodinov, Vincent Fortuin

Helmholtz, Germany

Building a Local AI Agent Assisting with Sensor Observation to Archives Framework (O2A)

Luca Greiner¹, Stefan Pinkernell¹, Roland Koppe², Sonja Hänzelmann¹

1: Alfred-Wegener-Institute for Polar and Marine Research, Data Science, Bremerhaven, Bremen, Germany; 2: Alfred-Wegener-Institute for Polar and Marine Research, Software Engineering, Bremerhaven, Bremen, Germany

SEA2LAND Navigator-GPT

Harsh Grover¹, Tobias Weigel¹, Manuel Frias², David Cabana³, Louis Celliers³, Anu Printsmann⁴

1: Hereon, Germany; 2: HELCOM; 3: GERICS; 4: Tallinn University

Messanger RNA Untranslated Region Design through Transformers

Lorenzo Guerci¹, Ewa Szczurek^1,2

1: Helmholtz Munich, Institute of Computational Biology, Germany; 2: Faculty of Mathematics, Informatics and Mechanics, University of Warsaw

Semantic Equilibrium Decoding for Open-Ended Medical Visual Question Answering

Luca Hagen¹, Johanna Paula Müller¹, Weitong Zhang², Mengyun Qaio³, Bernhard Kainz^1,2

1: FAU Erlangen-Nürnberg, Germany; 2: Imperial College London, UK; 3: UCL, UK

Single Cell PBMC Analysis Shows Cell Type Specific Changes On Inflammation In Both Depressed And Non-Depressed Individuals

Jonas Hagenberg^1,2, Janine Knauer-Arloth²

1: Helmholtz AI, Helmholtz Zentrum München, Germany; 2: Max Planck Institute of Psychiatry, München, Germany

Advancing Sea Ice Surface Classification by Self-Supervised Contrastive Learning for Radar Altimetry

Lena Happ^1,5, Stefan Hendricks¹, Conrad M Albrecht^2,4, Lars Kaleschke¹, Sonali Patil³, Riccardo Fellegara³, Dirk A. Lorenz⁵

1: Section for Sea Ice Physics, Alfred Wegener Institute, Germany; 2: Earth Observation Center, German Aerospace Center, Germany; 3: Institute of Software Technology, German Aerospace Center, Germany; 4: Earth and Environmental Engineering, Columbia University, USA; 5: Center for Industrial Mathematics, Bremen University, Germany

Analytic model-informed representations for sample-efficient learning of scattering patterns

Stefan Häusler, Michael Wagener, Stephan Förster, Marina Ganeva

Forschungszentrum Jülich GmbH, Germany

Imbalanced Classification with Quantum Kernel Alignment

Florian Heininger¹, Jeanette Miriam Lorenz³, Matthias Weidemüller², Niels Halama¹

1: German Cancer Research Center, Germany; 2: Heidelberg University; 3: Fraunhofer IKS, LMU Munich

Syxplain: An Agentic Framework for Explainable Scientific Hypothesis Generation from Data

Roland Hollós¹, Patrik Süli², Gergő Szabó¹, György Eigner²

1: HUN-REN, Hungary; 2: Obuda University, Hungary

Jülich Neutron Agent (JüNA): Vitess AI Agent

Ahmad Zainul Ihsan, Nicolo Violini, Klaus Lieutenant, Marina Ganeva

Jülich Centre for Neutron Science (JCNS), FZ Jülich, Germany

HPC Strategies for Fourier Neural Operators in Particle-In-Cell Plasma Simulations

Chelsea Maria John, Sriramkrishnan Muralikrishnan

Forschungszentrum Juelich, Germany

Diagnosing and Fixing Training Bottlenecks: A Case Study of a Foundation Model

Javad Kasravi¹, Christian Lessig², Timothy Hunter², Stefan Kesselheim¹

1: Jülich Supercomputing Centre, Forschungszentrum Jülich, 52428 Jülich, Germany; 2: ECMWF, 53175 Bonn, Germany

Advancing Explainability as a Differentiator in Machine Learning prediction models for Alzheimer’s Disease

Charles Kaumbutha^1,2, Shubhi Ambast^1,2, Karola Mai^1,2, Karoline Mauer^2,3, Matthias Becker^1,2

1: Modular HPC and AI, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; 2: Systems Medicine, German Center for Neurodegenerative Diseases (DZNE) e.V., 53127 Bonn, Germany; 3: PRECISE Platform for Genomics and Epigenomics at DZNE and University of Bonn, 53127 Bonn, Germany

Improving Pedestrian Detection through Temporal Movement Estimations

Yannick Kees, Elena Hoemann, Frank Köster, Sven Hallerbach

German Aerospace Center (DLR), Germany

Neural Networks as Varieties

Ismail Khalfaoui-Hassani, Stefan Kesselheim

Forschungszentrum Jülich, Germany

Surrogate Models for Severe Nuclear Accidents

Paul Kieckhefen^1,2, Jonas Dressner², Charlotte Debus², Markus Götz^1,2

1: Helmholtz AI, Germany; 2: Karlsruhe Institute of Technology, Germany

Training-free Uncertainty Guidance for Complex Visual Tasks with MLLMs

Sanghwan Kim^1,2,3, Rui Xiao^2,3, Stephan Alaniz⁴, Yongqin Xian⁵, Zeynep Akata^1,2,3

1: Helmholtz Zentrum München, Germany; 2: Technical University of Munich, Germany; 3: Munich Center for Machine Learning, Germany; 4: Télécom Paris, France; 5: Google, Switzerland

Helixer – a tool for ab initio gene calling combining Deep Learning and a Hidden Markov Model

Felicitas Kindel^1,2, Anthony Bolger¹, Björn Usadel^1,2,3, Alisandra Denton^2,3,4, Marie Bolger¹

1: Forschungszentrum Jülich, Germany; 2: Heinrich Heine Univsersität Düsseldorf, Germany; 3: Cluster of Excellence on Plant Sciences (CEPLAS), Germany; 4: Recursion, Valence Labs, Canada

metabeta - A fast neural model for Bayesian mixed-effects regression

Alex Kipnis, Marcel Binz, Eric Schulz

Human-Centered AI, Helmholtz Munich, Germany

Meta-Learning for Phenotypic Drug Discovery with Transformer Neural Processes

Michal Kmicikiewicz^1,2, Tommy Rochussen^2,3,4, Vincent Fortuin^3,4,6, Ewa Szczurek^1,5

1: Institute of AI for Health, Helmholtz Munich; 2: School of Computation, Information and Technology, Technical University of Munich; 3: Helmholtz AI; 4: Munich Center for Machine Learning; 5: Faculty of Mathematics, Informatics and Mechanics, University of Warsaw; 6: Department of Computer Science and Artificial Intelligence, University of Technology Nuremberg

Agentic Data Extraction and Dynamic Knowledge Graph Construction for Hydrogen Technology Research

Marjan Kohandani^1,2,3, Mohammad j. Eslamibidgoli^1,2, Michael H. Eikerling^1,2,3, Kourosh Malek^1,2

1: Theory and Computation of Energy Materials (IET-3), Institute of Energy Technologies, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany; 2: Centre for Advanced Simulation and Analytics (CASA), Simulation and Data Science Lab for Energy Materials (SDL-EM), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany; 3: Chair for Theory and Computation of Energy Materials, Faculty of Georesources and Materials Engineering, RWTH Aachen University, Germany

Diagnosing Shortcuts in Traffic Video Question Answering Datasets

Sena Korkut¹, María Alejandra Bravo^1,2,3, Sanghwan Kim^1,2,3, Zeynep Akata^1,2,3

1: Technical University of Munich, Germany; 2: Helmholtz Zentrum München, Germany; 3: Munich Center for Machine Learning, Germany

DREAMS: Preserving both Local and Global Structure in Dimensionality Reduction

Noël Kury^1,2, Dmitry Kobak^1,2, Sebastian Damrich^1,2

1: Hertie Institute for AI in Brain Health, Germany; 2: University of Tübingen, Germany

Factor dependencies and their associations with covariates in multimodal factor analysis

Małgorzata Łazęcka¹, Ewa Szczurek^2,1

1: University of Warsaw, Poland; 2: Helmholtz Center Munich, Germany

An Exchange Correlation Potential Database for Density Functional Machine Learning

Vincent Martinetto^1,2, Mani Lokamani¹, Attila Cangi²

1: Helmholtz Zentrum Dresden Rossendorf, Germany; 2: Center for Advanced Systems Understanding

Discovering Interpretable Visual Concepts in Monkey Visual Cortex Using Sparse Autoencoders

Lilly May^1,2, Atharv Suryawanshi¹, Steffen Schneider¹

1: Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Germany; 2: Department of Experimental Psychology, University of Oxford, UK

Incremental learning for continuous forest disturbance mapping using AlphaEarth embeddings

Francisco Mena, Simon Besnard, Martin Herold

GFZ Helmholtz Centre for Geosciences, Germany

Multimodal Machine Learning for Postoperative Atrial Fibrillation Prediction

Julian Mierisch¹, Christian Niklas², Rosa Klotz³, Axel Loewe¹

1: Karlsruhe Institute of Technology, Germany; 2: Medical Faculty Mannheim, Germany; 3: University Hospital Heidelberg, Germany

FrevaGPT: An LLM-Powered Assistant for Reproducible Climate Analysis

Koketso Michelle Molepo¹, Gizem Ekinci², Sebastian Willmann², Johanna Baehr³, Kevin Sieck⁴, Felix Oertel², Bianca Wentzel², Thomas Ludwig², Martin Bergemann², Jan Saynisch-Wagner¹, Christopher Kadow²

1: GFZ Helmholtz Centre for Geosciences, Germany; 2: German Climate Computing Center DKRZ, Germany; 3: Universität Hamburg, Germany; 4: Climate Service Center Germany (GERICS), Germany

Mind The Gap: Continuous Magnification Sampling For Pathology Foundation Models

Alexander Möllers^1,2,3, Julius Hense^1,2, Florian Schulz^1,2, Timo Milbich³, Maximilian Alber³, Lukas Ruff^3,4

1: Technical University Berlin, Germany; 2: Berlin Institute for the Foundations of Learning and Data; 3: Aignostics Gmbh; 4: Charité, Universitätsmedizin Berlin

Grounding Large Language Models in Formal Solvers via Unified Planning: Towards High-Accuracy Natural Language Planning

João Areias Saraiva, Thomas Kirste

Hybrid Methods in Artificial Intelligence and Machine Learning, University of Rostock, Germany

A decentralized Swarm Learning framework for 90-Day outcome prediction for acute ischaemic stroke

Arnab Bandyopadhyay¹, Omid Shirvani¹, Jilles Vreeken², Anna Aschenbrenner¹, Joachim Schultze¹

1: DZNE, Germany; 2: CISPA, Germany

Post-training makes large language models less human-like

Marcel Binz, Psych-201 Consortium, Eric Schulz

Helmholtz Munich, Germany

Multiscale Orthogonal Phenotype Detection in Multiplexed Spatial Datasets

Ali Oğuz Can^1,2, Gizem Mansour¹, Alessandro Palma^1,2, Malte Benedikt Kuehl³, Andres Gonzalez Suarez¹, Kenji Schorpp¹, Ina Rothenaigner¹, Kamyar Hadian¹, Victor Puelles³, Fabian Theis^1,2, Nicolas Battich^1,2

1: Helmholtz Munich, Germany; 2: Technical University of Munich; 3: Aarhus University

A Domain-Specialized Multimodal Foundation Model for Interpreting Sentinel-2 True Color Imagery in Flood Disaster Response

Luca Chiarabini, Daniela Espinoza Molina, Andrés Camero Unzueta

DLR, Germany

A Hematology Foundation Model Enables Blood Cancer Screening from Peripheral Blood Smears

Muhammed Furkan Dasdelen¹, Fatih Ozlugedik¹, Ivan Kukuljan¹, Ario Sadafi¹, Matthias Hehr¹, Christian Pohlkamp², Carsten Marr¹

1: Helmholtz Munich, Germany; 2: Munich Leukemia Laboratory

Surrogate Modeling of Scale-Bridging Dislocation-Driven Plasticity through Latent Dynamics and Microstructure Descriptors

Aytekin Demirci¹, Stefan Sandfeld^1,2

1: Institute for Advanced Simulations – Materials Data Science and Informatics (IAS-9) Forschungszentrum Jülich GmbH 52425 Jülich, Germany; 2: Chair of Materials Data Science and Materials Informatics, Faculty 5 Georesources and Materials Engineering, RWTH Aachen University 52056 Aachen, Germany

Neural Quasiprobabilistic Likelihood Ratio Estimation

Matthew Drnevich², Stephen Jiggins¹, Kyle Cranmer³

1: DESY, Germany; 2: New York University, USA; 3: University of Wisconsin-Madison, USA

NVIDIA Earth-2: Open Models, Accessible Hardware, and the Future of AI for Weather and Climate

David Hall, Mike Pritchard, Karthik Kashinath, Noah Brenowitz

NVIDIA Corporation

Anomaly Detection in Prediction Markets: Identifying Coordinated Information Advantage

David Hughes

Stelia, United Kingdom

Amortized Bayesian Multilevel Model of Bacterial Cell-Cycle with BayesFlow

Laura Jenniches¹, Lars Barquist^1,2,3

1: Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany; 2: Department of Biology, University of Toronto, Mississauga, ON, Canada; 3: Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada

Exploring the Effectiveness of Pretraining Task Alignment for Self-Supervised Learning in a Low-Data Regime

Shivangi Kirti¹, Binh Duong Nguyen¹, Stefan Sandfeld^1,2

1: Institute for Advanced Simulations — Materials Data Science and Informatics (IAS-9), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany; 2: Chair of Materials Data Science and Materials Informatics, Faculty 5 — Georesources and Materials Engineering, RWTH Aachen University, 52056 Aachen, Germany

Taming Multimodal Posteriors over Rotations: A Geometric Approach to Bayesian Alignment in Cryo-EM and Beyond

Shantanu Kodgirwar^1,2,3, Jan Rothhardt^1,2,3,4, Michael Habeck^3,5,6

1: Helmholtz Institute Jena, Germany; 2: GSI Helmholtzzentrum für Schwerionenforschung, Germany; 3: Friedrich Schiller University Jena, Germany; 4: Fraunhofer Institute for Applied Optics and Precision Engineering, Germany; 5: University Hospital Jena, Germany; 6: Max Plank Institute for Multidisciplinary Sciences, Germany

Sample Efficient Generative Molecular Optimization with Joint Self-Improvement

Serra Korkmaz¹, Adam Izdebski^1,2, Jonathan Pirnay^3,4, Rasmus Møller-Larsen^1,2, Michal Kmicikiewicz^1,2, Pankhil Gawade^1,2, Dominik G. Grimm^2,3,4, Ewa Szczurek^1,5

1: Helmholtz Munich, Germany; 2: Technical University of Munich, TUM School of Computation, Information and Technology; 3: Technical University of Munich, Campus Straubing for Biotechnology and Sustainability; 4: University of Applied Sciences Weihenstephan Triesdorf; 5: Faculty of Mathematics, Informatics and Mechanics, University of Warsaw

Assessing the Performance–Efficiency Trade-off of Foundation Models in Probabilistic Electricity Price Forecasting

Jan Niklas Lettner, Hadeer El Ashhab, Veit Hagenmeyer, Benjamin Schäfer

Karlsruhe Institute of Technology, Germany

Mind the Gap – From expectation to reality in agentic AI

Sebastian Lobentanzer^1,2

1: Helmholtz Munich, Germany; 2: German Center for Diabetes Research, Germany

Genomic language model based prediction of transcription start sites in twelve yeast species

Maria Ryabtseva¹, Tilman Hoffbauer¹, Julien Gagneur^1,2

1: Computation Molecular Medicine, School of Computation, Information and Technology, TU Munich, Germany; 2: Computational Health Center, Helmholtz Center Munich, Germany

Differentiable Wave-Optics for Single-Shot X-Ray Phase-Contrast Imaging of Plasma Targets

Ritz Ann Aguilar¹, Long Yang¹, Lingen Huang¹, Michael Bussmann^1,2, Ulrich Schramm^1,3, Thomas Cowan^1,4, Jeffrey Kelling^1,5

1: Helmholtz-Zentrum Dresden-Rossendorf, Germany; 2: Center for Advanced Systems Understanding, Germany; 3: Technische Universität Dresden, Germany; 4: European XFEL, Germany; 5: Technische Universität Chemnitz, Germany

Performance Bounds for Reliability and Hallucination Risk in Remote-Sensing Super-Resolution

David Iagaru^1,2, Jakob Gawlikowski¹

1: German Aerospace Center (DLR), Remote Sensing Technology Institute, Germany; 2: Ecole Polytechnique, Department of Applied Mathematics, Paris, France.

CaMoEMMIL: Clustering-Aware Mixture Of Experts For Multimodal Multiple Instance Learning In Lung Transplantation

Dinesh Adhithya Haridoss, Ewa Szczurek

Helmholtz Munich, Germany

Modelling Patient Variation Across Datasets And Diseases With Contrastive Learning On Single-Cell Data

Vladimir A. Shitov^1,4, Benjamin M. Frey^1,4, Mohammad Moghareh Dehkordi², Till Richter^1,2, Mojtaba Bahrami^1,3, Emma Maria Schonner², Youssef Naciri Zerta¹, Fabian J. Theis^1,2,3, Malte D. Luecken^1,4

1: Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Munich, Germany; 2: School of Computing, Information and Technology, Technical University of Munich, Munich, Germany.; 3: TUM School of Life Sciences Weihenstephan, Technical University of Munich, Germany.; 4: Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive and Institute of Lung Health and Immunity, Helmholtz Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.

No Data? No Problem: Robust Vision-Tabular Learning with Missing Values

Marta Hasny^1,2, Laura Daza^1,2, Keno Bressem², Maxime Di Folco^1,2,3, Julia A. Schnabel^1,2,4

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: Telecom Paris, France; 4: King's College London, UK

Reliable and Sustainable AI for Scientific Discovery

Gitta Kutyniok

LMU Munich, Germany

Bridging Scales: Adapting Human 3D Foundation Models for Mouse Micro-CT Phenotyping

Yoland Savriama, Arnd Heuser

Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft, Germany

TiViT: Time Series Representations Lie Hidden in Pretrained Vision Transformers

Simon Roschmann^1,2,3,4, Quentin Bouniot^1,2,3,4, Vasilii Feofanov⁵, Ievgen Redko⁵, Zeynep Akata^1,2,3,4

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: Munich Center for Machine Learning, Germany; 4: Munich Data Science Institute, Germany; 5: Paris Noah’s Ark Lab, France

Physics-Aligned Self-Supervised Learning for Scientific Imaging

Bashir Kazimi¹, Stefan Sandfeld^1,2

1: Institute for Advanced Simulation—Materials Data Science and Informatics (IAS-9), Forschungszentrum Jülich, Germany; 2: Chair of Materials Data Science and Materials Informatics, Faculty 5—Georesources and Materials Engineering, RWTH Aachen University,

MADRNA: A Physics-Informed Machine-Learned Coarse-Grained Force Field for RNA

Emile de Bruyn¹, Anton Dorn¹, Fabrice von der Lehr², Philipp Knechtges², Alexander Schug³, Stefan Kesselheim¹

1: Forschungszentrum Jülich (FZJ), Germany; 2: Deutsches Zentrum für Luft- und Raumfahrt (DLR), Germany; 3: Karlsruhe Institute of Technology, Germany

Inverse Design of Multilayer Thin Films using Robust Deep Learning

Jonas Schaible^1,2, Asena Karolin Özdemir³, Charlotte Debus³, Sven Burger², Achim Streit³, Christiane Becker^1,4, Klaus Jäger^1,2, Markus Götz^3,5

1: Helmholtz Centre for Materials and Energy, Germany; 2: Zuse Institute Berlin, Germany; 3: Scientific Computing Center, Germany; 4: HTW Berlin, Germany; 5: Helmholtz AI, Germany

AI-quifer – Predicting Offshore Groundwater Occurrences through the Application of Artificial Intelligence

Laura Haffert¹, Marion Jegen¹, Christian Siebert², Caroline Arnold³, Tino Rödiger²

1: GEOMAR Helmholtz Centre for Ocean Research Kiel, Germany; 2: UFZ, Helmholtz Centre for Environmental Research, Germany; 3: Helmholtz Centre Hereon, Germany

AI and Future of Medicine

Daniel Rueckert

Technical University of Munich, Germany

Deep Graph Learning for Temporal Data

Ingo Scholtes

University of Würzburg, Germany

Neurosymbolic Models of Uncertainty and Logical Reasoning

Annemarie Friedrich

Universität Augsburg, Germany

Rethinking the Foundations of Weather and Climate Modelling

Martin Schultz

FZJ, Germany

A Multi-Sensor Foundation Model for Earth Observation

Nassim Ait Ali Braham^1,2, Aaron Christian Banze^1,3, Julien Mairal⁴, Jocelyn Chanussot⁴, Conrad Martin Albrecht¹, Xiao Xiang Zhu²

1: German Aerospace Center (DLR), Germany; 2: Technical University of Munich (TUM), Germany; 3: University of the Bundeswehr Munich, Germany; 4: Universite Grenoble Alpes, Inria, CNRS, Grenoble INP, LJK, France

OneProtGPT: Bridging Protein Embeddings and Large Language Models for Protein Understanding

Javad Kasravi, Alina Bazarova, Stefan Kesselheim

Jülich Supercomputing Centre, Forschungszentrum Jülich, 52428 Jülich, Germany

AMPFormer: A Peptide Foundation Model for Antimicrobial Discovery

Pankhil Gawade^1,2, Adam Izdebski^1,2, Marcelo DT Torres⁴, Cesar De La Fuente-nunez⁴, Ewa Szczurek^1,3

1: Institute of AI for Health, Helmholtz Zentrum Munchen; 2: Technical University of Munich, TUM School of Computation, Information and Technology; 3: Faculty of Mathematics, Informatics and Mechanics, University of Warsaw; 4: University of Pennsylvania, Philadelphia, PA, USA.

AI for Fundamental Physics: Learning from Big Data at the LHC

Judith Katzy

DESY, Germany

Reinforce Adjoint Matching: Scaling RL Post-Training of Diffusion and Flow-Matching Models

Andreas Bergmeister¹, Stefanie Jegelka¹, Jakiw Pidstrigach², Nikolas Nüsken³, Carles Domingo-Enrich⁴

1: TUM, Germany; 2: University of Oxford, United Kingdom; 3: King’s College London, United Kingdom; 4: Microsoft Research, United States

SurvDiff: A Diffusion Model for Generating Synthetic Data in Survival Analysis

Marie Brockschmidt^1,2, Maresa Schröder^1,2, Stefan Feuerriegel^1,2

1: LMU Munich; 2: Munich Center for Machine Learning (MCML)

Stitch: Training-Free Position Control in Multimodal Diffusion Transformers

Jessica Bader^1,2, Mateusz Pach^1,2, María A. Bravo^1,2, Serge Belongie³, Zeynep Akata^1,2

1: Helmholtz Munich, Germany; 2: Technical University of Munich; 3: University of Copenhagen

The Mean is the Mirage: Entropy-Adaptive Model Mergingunder Heterogeneous Domain Shifts in Medical Imaging

Sameer Ambekar^1,2,3,4, Reza Nasirigerdeh^5,4, Peter J. Schuffler^5,1,4, Lina Felsner¹, Daniel M. Lang^1,2, Julia A. Schnabel^1,2,3,5,6

1: School of Computation, Information and Technology, Technical University of Munich, Germany; 2: Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich, Germany; 3: relAI – Konrad Zuse School of Excellence in Reliable AI; 4: Munich Center for Machine Learning (MCML); 5: Institute of Pathology, Technical University of Munich, Germany; 6: School of Biomedical Engineering and Imaging Sciences, King’s College London, UK.

ConvexGating infers gating strategies from clusters in single cell cytometry data

Vincent D Friedrich^1,2, Karola Mai^3,4, Thomas P Hofer⁵, Elfriede Nößner⁵, Lorenzo Bonaguro^3,6,7, Celia L Hartmann^3,8, Aleksej Frolov^3,8,9, Caterina Carraro^3,6, Doaa Hamada^3,10,11, Mehrnoush Hadaddzadeh-Shakiba^3,8, Heidi Theis⁷, Dalila Juliana Silva Ribeiro¹², Dagmar Wachten¹², F Thomas Wunderlich¹³, Markus Scholz^1,14, Fabian J Theis^15,16,17, Matthias Becker^3,4, Marc D Beyer^3,7,8, Joachim L Schultze^3,6,7, Maren Büttner^3,7,15

1: University of Leipzig, Institute for Medical Informatics, Statistics, and Epidemiology, Leipzig, Germany; 2: Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), Leipzig, Germany; 3: Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany; 4: Modular High Performance Computing and Artificial Intelligence, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; 5: Research Group Tissue Control of Immunocytes, Helmholtz Center Munich, Munich, Germany; 6: Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany; 7: PRECISE Platform for Single Cell Genomics and Epigenomics, DZNE and University of Bonn and West German Genome Center (WGGC), Bonn, Germany; 8: Immunogenomics & Neurodegeneration, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany; 9: Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia; 10: Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases and the University of Bonn, Germany; 11: Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Egypt; 12: Institute of Innate Immunity, Biophysical Imaging, Medical Faculty, University of Bonn, Bonn, Germany; 13: Max Planck Institute for Metabolism Research, Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), Cologne, Germany; 14: University of Leipzig, Faculty of Mathematics and Computer Science, Leipzig, Germany; 15: Institute of Computational Biology, Helmholtz Center Munich, Germany; 16: Department of Mathematics, Technical University of Munich, Germany; 17: TUM School of Life Sciences Weihenstephan, Technical University of Munich, Germany

From Drop-off to Recovery: A Mechanistic Analysis of Segmentation in MLLMs

Boyong Wu^1,2, Sanghwan Kim^1,2,3, Zeynep Akata^1,2,3

1: Technical University of Munich, Germany; 2: Helmholtz Munich, Germany; 3: Munich Center for Machine Learning (MCML), Germany

Cross Modalities Pretraining of Sparse Lidar and Dense Image Foundation Model for Global Carbon Stock Mapping

Audita Widya Astuti^1,2, Aldino Rizaldy¹, Gunjan Joshi¹, Weikang Yu¹, Peter Steinbach¹, Qi Zhang², Xiao Xiang Zhu², Pedram Ghamisi¹

1: Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; 2: Chair of Data Science in Earth Observation, Technical University of Munich, Munich, Germany

ICD-Code Extraction from Clinical Notes using Large Language Models in a RAG pipeline

Ludwig Krause¹, Martin Dyrba^1,2, Thomas Kirste¹, João Areias Saraiva^1,2

1: Hybrid Methods in Artificial Intelligence and Machine Learning, University of Rostock, Germany; 2: German Center for Neurodegenerative Diseases, Rostock, Germany

Causal Machine Learning for Predictive Biomarker Discovery and Subgroup Refinement in Metastatic Colorectal Cancer

Alina J. Arneth¹, Julian W. Holch^2,3,4, Octavia-Andreea Ciora^5,6, Volker Heinemann^2,3,4, Stefan Feuerriegel^5,6, Michael P. Menden^1,7

1: Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Australia; 2: Department of Medicine III and Comprehensive Cancer Center Munich, University Hospital, Ludwig-Maximilians University Munich, Germany; 3: Comprehensive Cancer Center Munich, Germany; 4: German Cancer Consortium (DKTK), partner site Munich, German Cancer Research Center (DKFZ), Germany; 5: LMU Munich School of Management, LMU Munich, Germany; 6: Munich Center for Machine Learning, Germany; 7: Computational Health Center, Institute of Computational Biology, Helmholtz Munich, Germany

Neural Operator-Based Surrogate Modeling for Efficient Prediction of Temperature and Residual Stresses in Tempered Glass

Tarek Hussein, Johannes Schilp

Universität Augsburg, Germany

GRIP: Physics-Informed Neural Network for Gradient Retention Time Prediction in Liquid Chromatography

Kevin George¹, F.P. Jake Haeckl¹, Gerrit Großmann², Alexey Gurevich¹, Azat Tagirdzhanov¹

1: Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Germany; 2: German Research Center for Artificial Intelligence (DFKI) Kaiserslautern

Who Owns Human Experience? Ethical Implications of Transforming Tacit Knowledge into Neural Models

Christopher Koska¹, Markus Schatzl²

1: University Augsburg, Germany; 2: ergonoi GbR

Towards Useful and Private Synthetic Omics: Community Benchmarking of Generative Models for Transcriptomics Data

Hakime Öztürk^1,2, Tejumade Afonja³, Joonas Jälkö⁴, Ruta Binkyte³, Pablo Rodriguez-Mier⁵, Sebastian Lobentanzer⁶, Andrew Wicks^7,8, Jules Kreuer⁹, Sofiane Ouaari⁹, Nico Pfeifer⁹, Shane Menzies¹⁰, Sikha Pentyala¹⁰, Daniil Filienko¹⁰, Steven Golob¹⁰, Patrick McKeever¹⁰, Jineta Banerjee¹¹, Luca Foschini¹¹, Martine De Cock^10,12, Julio Saez-Rodriguez¹³, Mario Fritz³, Oliver Stegle^1,2, Antti Honkela⁴

1: European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany; 2: Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany; 3: CISPA Helmholtz Center for Information Security, Saarbrücken, Germany; 4: University of Helsinki, Finland; 5: Heidelberg University, Germany; 6: Helmholtz Munich, Germany; 7: Division of Tumorigenesis and Molecular Cancer Prevention, German Cancer Research Center (DKFZ), Heidelberg, Germany; 8: DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Germany; 9: Eberhard Karls Universität Tübingen, Germany; 10: University of Washington Tacoma, USA; 11: Sage Bionetworks, Seattle, USA; 12: Ghent University, Ghent, Belgium; 13: European Bioinformatics Institute (EMBL-EBI), UK

HemAutomaton: A lightweight NCA-based pipeline for large-scale extraction of white blood cells from whole slide images

Michael Deutges¹, Altana Namsaraeva¹, Tabita Ghete², Markus Metzler², Carsten Marr¹, Maximilian Buser¹

1: Helmholtz Munich, Germany; 2: Universitätsklinikum Erlangen, Germany

DeepRVAT2: Unified Modeling of Coding and Regulatory Rare Variation at Genome Scale for Enhanced Gene Discovery and Diagnostics

Eva Holtkamp^1,2, Shubhankar Londhe^1,2, Anna Starovoit², Merit Back², Thibault Bechtler⁴, Brian Clarke⁴, Oliver Stegle^4,5,6, Julien Gagneur^1,2,3

1: Computational Health Center, Helmholtz Center Munich, Neuherberg, Germany; 2: chool ofComputation, Information and Technology, Technical University of Munich, Garching, Germany; 3: Institute of Human Genetics, School of Medicine, Technical University of Munich, Munich, Germany; 4: German Cancer Research Center (DKFZ), Heidelberg, Germany; 5: European Molecular Biology Laboratory (EMBL), Heidelberg, Germany; 6: Heidelberg University, Germany

The Mean is the Mirage: Entropy-Adaptive Model Mergingunder Heterogeneous Domain Shifts in Medical Imaging

Sameer Ambekar^1,2,3,4, Reza Nasirigerdeh^5,4, Peter J. Schuffler^5,1,4, Lina Felsner¹, Daniel M. Lang^1,2, Julia A. Schnabel^1,2,3,5,6

1: School of Computation, Information and Technology, Technical University of Munich, Germany; 2: Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich, Germany; 3: relAI – Konrad Zuse School of Excellence in Reliable AI; 4: Munich Center for Machine Learning (MCML); 5: Institute of Pathology, Technical University of Munich, Germany; 6: School of Biomedical Engineering and Imaging Sciences, King’s College London, UK.

ConvexGating infers gating strategies from clusters in single cell cytometry data

Vincent D Friedrich^1,2, Karola Mai^3,4, Thomas P Hofer⁵, Elfriede Nößner⁵, Lorenzo Bonaguro^3,6,7, Celia L Hartmann^3,8, Aleksej Frolov^3,8,9, Caterina Carraro^3,6, Doaa Hamada^3,10,11, Mehrnoush Hadaddzadeh-Shakiba^3,8, Heidi Theis⁷, Dalila Juliana Silva Ribeiro¹², Dagmar Wachten¹², F Thomas Wunderlich¹³, Markus Scholz^1,14, Fabian J Theis^15,16,17, Matthias Becker^3,4, Marc D Beyer^3,7,8, Joachim L Schultze^3,6,7, Maren Büttner^3,7,15

1: University of Leipzig, Institute for Medical Informatics, Statistics, and Epidemiology, Leipzig, Germany; 2: Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), Leipzig, Germany; 3: Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany; 4: Modular High Performance Computing and Artificial Intelligence, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; 5: Research Group Tissue Control of Immunocytes, Helmholtz Center Munich, Munich, Germany; 6: Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany; 7: PRECISE Platform for Single Cell Genomics and Epigenomics, DZNE and University of Bonn and West German Genome Center (WGGC), Bonn, Germany; 8: Immunogenomics & Neurodegeneration, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany; 9: Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia; 10: Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases and the University of Bonn, Germany; 11: Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Egypt; 12: Institute of Innate Immunity, Biophysical Imaging, Medical Faculty, University of Bonn, Bonn, Germany; 13: Max Planck Institute for Metabolism Research, Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), Cologne, Germany; 14: University of Leipzig, Faculty of Mathematics and Computer Science, Leipzig, Germany; 15: Institute of Computational Biology, Helmholtz Center Munich, Germany; 16: Department of Mathematics, Technical University of Munich, Germany; 17: TUM School of Life Sciences Weihenstephan, Technical University of Munich, Germany

From Drop-off to Recovery: A Mechanistic Analysis of Segmentation in MLLMs

Boyong Wu^1,2, Sanghwan Kim^1,2,3, Zeynep Akata^1,2,3

1: Technical University of Munich, Germany; 2: Helmholtz Munich, Germany; 3: Munich Center for Machine Learning (MCML), Germany

Cross Modalities Pretraining of Sparse Lidar and Dense Image Foundation Model for Global Carbon Stock Mapping

Audita Widya Astuti^1,2, Aldino Rizaldy¹, Gunjan Joshi¹, Weikang Yu¹, Peter Steinbach¹, Qi Zhang², Xiao Xiang Zhu², Pedram Ghamisi¹

1: Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; 2: Chair of Data Science in Earth Observation, Technical University of Munich, Munich, Germany

ICD-Code Extraction from Clinical Notes using Large Language Models in a RAG pipeline

Ludwig Krause¹, Martin Dyrba^1,2, Thomas Kirste¹, João Areias Saraiva^1,2

1: Hybrid Methods in Artificial Intelligence and Machine Learning, University of Rostock, Germany; 2: German Center for Neurodegenerative Diseases, Rostock, Germany

Causal Machine Learning for Predictive Biomarker Discovery and Subgroup Refinement in Metastatic Colorectal Cancer

Alina J. Arneth¹, Julian W. Holch^2,3,4, Octavia-Andreea Ciora^5,6, Volker Heinemann^2,3,4, Stefan Feuerriegel^5,6, Michael P. Menden^1,7

1: Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Australia; 2: Department of Medicine III and Comprehensive Cancer Center Munich, University Hospital, Ludwig-Maximilians University Munich, Germany; 3: Comprehensive Cancer Center Munich, Germany; 4: German Cancer Consortium (DKTK), partner site Munich, German Cancer Research Center (DKFZ), Germany; 5: LMU Munich School of Management, LMU Munich, Germany; 6: Munich Center for Machine Learning, Germany; 7: Computational Health Center, Institute of Computational Biology, Helmholtz Munich, Germany

Neural Operator-Based Surrogate Modeling for Efficient Prediction of Temperature and Residual Stresses in Tempered Glass

Tarek Hussein, Johannes Schilp

Universität Augsburg, Germany

GRIP: Physics-Informed Neural Network for Gradient Retention Time Prediction in Liquid Chromatography

Kevin George¹, F.P. Jake Haeckl¹, Gerrit Großmann², Alexey Gurevich¹, Azat Tagirdzhanov¹

1: Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Germany; 2: German Research Center for Artificial Intelligence (DFKI) Kaiserslautern

Who Owns Human Experience? Ethical Implications of Transforming Tacit Knowledge into Neural Models

Christopher Koska¹, Markus Schatzl²

1: University Augsburg, Germany; 2: ergonoi GbR

Towards Useful and Private Synthetic Omics: Community Benchmarking of Generative Models for Transcriptomics Data

Hakime Öztürk^1,2, Tejumade Afonja³, Joonas Jälkö⁴, Ruta Binkyte³, Pablo Rodriguez-Mier⁵, Sebastian Lobentanzer⁶, Andrew Wicks^7,8, Jules Kreuer⁹, Sofiane Ouaari⁹, Nico Pfeifer⁹, Shane Menzies¹⁰, Sikha Pentyala¹⁰, Daniil Filienko¹⁰, Steven Golob¹⁰, Patrick McKeever¹⁰, Jineta Banerjee¹¹, Luca Foschini¹¹, Martine De Cock^10,12, Julio Saez-Rodriguez¹³, Mario Fritz³, Oliver Stegle^1,2, Antti Honkela⁴

1: European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany; 2: Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany; 3: CISPA Helmholtz Center for Information Security, Saarbrücken, Germany; 4: University of Helsinki, Finland; 5: Heidelberg University, Germany; 6: Helmholtz Munich, Germany; 7: Division of Tumorigenesis and Molecular Cancer Prevention, German Cancer Research Center (DKFZ), Heidelberg, Germany; 8: DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Germany; 9: Eberhard Karls Universität Tübingen, Germany; 10: University of Washington Tacoma, USA; 11: Sage Bionetworks, Seattle, USA; 12: Ghent University, Ghent, Belgium; 13: European Bioinformatics Institute (EMBL-EBI), UK

Multimodal Representation Learning for Pan-Cancer Type Classification Using Attention-Based Set Encoding and Contrastive Pre-Training

Fabian Janosch Krüger, Bora Uyar, Altuna Akalin

Max Delbrück Center for Molecular Medicine, Germany

Higher-Order Hit-&-Run Samplers for Linearly Constrained Densities

Richard D. Paul^1,2, Anton Stratmann¹, Johann F. Jadebeck¹, Martin Beyß¹, Hanno Scharr¹, David Rügamer^2,3, Katharina Nöh¹

1: Forschungszentrum Jülich, Germany; 2: Department of Statistics, LMU Munich; 3: Munich Center for Machine Learning (MCML)

Simple Yet Effective: Basic Population and Evolutionary Statistics Contain Richest Information to Infer Systematic Variant Effects

Zhengyuan Xue^1,2,3, Francesco Paolo Casale^2,4, Daniel Kotlarz^1,5

1: 1Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; 2: School of Computation, Information and Technology, Technical University of Munich, Garching, Germany; 3: Helmholtz Association—Munich School for Data Science (MUDS), Munich, Germany; 4: Helmholtz Pioneer Campus, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; 5: Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig Maximilian University Munich, Munich, Germany

Bringing Gaps between Farmers and AI with XAI Principles

Chandrabali Karmakar¹, Arnab Bhowmik², Dumitru Corneliu Octavian³

1: German Aerospace Center (DLR), Germany; 2: German Aerospace Center (DLR), Germany; 3: German Aerospace Center (DLR), Germany

Abstracts Explorer: LLM-Powered Semantic Exploration of Scientific Conference Proceedings

Till Korten, Peter Steinbach

Helmholtz Zentrum Dresden Rossendorf (HZDR), Germany

Systematic benchmarking of imaging-based spatial transcriptomics preprocessing

Louis Kümmerle¹, Daria Romanovskaia^1,2, Habib Rehman³, Valentina Beliaeva^1,2, Fabian Theis¹, Malte Lücken^1,2

1: Institute of Computational Biology, Helmholtz Munich, Germany; 2: Institute of Lung Health and Immunity, Helmholtz Munich, Germany; 3: Indiana University School of Medicine

Dynamic Decision Learning: Test-Time Evolution for Abnormality Grounding in Rare Diseases

Jun Li¹, Mingxuan Liu², Jiazhen Pan¹, Che Liu³, Wenjia Bai³, Cosmin Bercea¹, Julia Schnabel^1,4,5

1: Technical University of Munich, Germany; 2: University of Trento, Italy; 3: Imperial College London, United Kingdom; 4: Helmholtz Munich, Germany; 5: King's College London, United Kingdom

Geometry-Aware Edge Pooling for Graph Neural Networks

Katharina Limbeck^1,2, Lydia Mezrag^3,4, Guy Wolf^3,4, Bastian Rieck^1,5

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: University of Montreal, Canada; 4: Mila - Quebec Artificial Intelligence Institute, Canada; 5: University of Fribourg, Switzerland

Phenotype-driven virtual screening accelerates therapeutic discovery for idiopathic pulmonary fibrosis

Kevin Merchant¹, Adam Izdebski¹, Serra Korkmaz¹, Arun Kumar Verma¹, Michael Gerckens¹, Gerald Gerald Burgstaller¹, Ewa Szczurek^1,2

1: Helmholtz Munich; 2: Faculty of Mathematics, Informatics and Mechanics, University of Warsaw

Machine Learning-based RNA Design for the Development of Efficient mRNA Therapeutics

Zahra Mir, Annalisa Marsico

Helmholtz Munich, Computational Health Center, Computational Biology (ICB), Germany

Reinterpreting Protein Sequences as Structured Signals: A CNN-Residual Approach to Neuropeptide Classification

Ana Beatriz Miranda Valentin¹, Marcus Vinicius da Silva Rodrigues¹, Robson Parmezan Bonidia¹, Elisângela Aparecida da Silva Lizzi¹, Ulisses Nunes da Rocha², Glaucia Maria Bressan¹

1: Federal University of Technology-Paraná, Brazil; 2: Helmholtz Centre for Environmental Research, Deutschland

Extracting 1D JWST Spectra from 2D Spectrograms with Deep Learning

Soorya Narayan¹, William Gillard¹, Stephane Ayache², Julien Zoubian¹

1: Centre de Physique des Particules de Marseille, France; 2: Laboratoire d'Informatique et des Systèmes, Marseille, France

Segmentation of glands in big cohort data by deep learning

Phuong Thanh Nguyen, Hans J. Grabe, Mark O. Wielpütz, Alexander Teumer

Universitätsmedizin Greifswald, Germany

Subclass-Conditioned Flow Matching for Long-Tailed Chest X-Ray Augmentation

Felix Nützel¹, Mischa Dombrowski¹, Bernhard Kainz^1,2

1: Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany; 2: Imperial College London, UK

MoA: Mixture of Aggregators Improves Slide-Level Diagnosis in Computational Pathology

Fatih Ozlugedik^1,3, Furkan Dasdelen^1,2,3, Rao Muhammed Umer¹, Carsten Marr^1,3

1: Helmholtz Munich, Germany; 2: TUM; 3: LMU

Topic Modeling and Opinion Analysis of Hyperloop Discussions on Twitter Using Latent Dirichlet Allocation

Kanak Pandit^1,4, Aditeya Prajapati², Sanyam Jain³, Steve Fernandes⁵, Aditya Ranjan Shandliya⁶, Muhammad Saeed^1,4,7

1: University of Stuttgart , Germany; 2: University of Southern California, USA; 3: Boston University, USA; 4: ARENA2036 e.V.; 5: University of Mumbai, India; 6: Hochschule Bremen, Germany; 7: Swinburne University of Technology, Melbourne, Australia

Sentiment Analysis of Indian Hyperloop Tweets for Opinion Inversion Prediction

Kanak Pandit^1,4, Sanyam Jain³, Prem Sharma⁵, Aditeya Prajapati², Upkar Chaurasiya⁷, Muhammad Saeed^1,4,6

1: University of Stuttgart, Germany; 2: University of Southern California, USA; 3: Boston University, USA; 4: ARENA2036, Germany; 5: Deakin University; 6: Swinburne University of Technology, Australia; 7: University of Mumbai, India

Test-time augmentation with synthetic data addresses distribution shifts in spectral imaging

Ahmad Bin Qasim^1,2,3, Alessandro Motta¹, Alexander Studier-Fischer⁴, Jan Sellner^1,2,3,5, Leonardo Ayala¹, Marco Hübner^1,3, Marc Bressan⁴, Berkin Özdemir⁴, Karl Friedrich Kowalewski^4,6, Felix Nickel^4,7, Silvia Seidlitz^1,2,3,5, Lena Maier-Hein^1,2,3,5,7

1: Division of Intelligent Medical Systems (IMSY), German Cancer Research Center (DKFZ), Heidelberg, Germany; 2: Helmholtz Information and Data Science School for Health, Karlsruhe/Heidelberg, Germany; 3: Faculty of Mathematics and Computer Science, Heidelberg University, Heidelberg, Germany; 4: Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany; 5: National Center for Tumor Diseases (NCT), A Partnership between DKFZ and University Medical Center Heidelberg, Heidelberg, Germany; 6: Department of Urology, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany; 7: Medical Faculty, Heidelberg University, Heidelberg, Germany

Physics-Aware Implicit Neural Representations for Extreme Compression of Coherent X-ray Holographic Data

Vahid Rahmani¹, Johannes Hagemann¹, Christian Schroer^1,2,3

1: Deutsches Elektronen-Synchrotron DES, Germany; 2: Department Physik, Universität Hamburg UHH, Germany; 3: HELMHOLTZ IMAGING

SplineFlow: Flow Matching for Dynamical Systems with B-Spline Interpolants

Santanu Rathod

CISPA Helmholtz Center for Information Security, Germany

Optimal conversion from Rényi Differential Privacy to $f$-Differential Privacy

Anneliese Riess^1,2, Juan Felipe Gomez³, Flavio du Pin Calmon³, Julia Schnabel^1,2, Georgios Kaissis⁴

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: Harvard University, USA; 4: Hasso-Plattner-Institut, Germany

SOTAlign: Semi-Supervised Alignment of Unimodal Vision and Language Models via Optimal Transport

Simon Roschmann^1,2,3,4, Paul Krzakala^5,6, Sonia Mazelet⁶, Quentin Bouniot^1,2,3,4, Zeynep Akata^1,2,3,4

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: Munich Center for Machine Learning, Germany; 4: Munich Data Science Institute, Germany; 5: Télécom Paris, France; 6: École Polytechnique, France

AtlasAlign: PointTransformer-based alignment of spatial omics to mouse brain common coordinate framework

Josef Salg^1,2, Wasim Aftab², Christian Schiffer³, Hannah Spitzer^2,4

1: Technical University of Munich (TUM), Germany; 2: Institute for Stroke and Dementia Research (ISD), Germany; 3: Institute of Neuroscience and Medicine (INM-1) Forschungszentrum Jülich, Germany; 4: Institute of Computational Biology, Helmholtz Munich, Germany

UdonPred: Untangling Protein Intrinsic DisorderPrediction

Julius Schlensok^1,2, David Wagemann¹, Tobias Senoner¹, Markus Haak³, Burkhard Rost^1,4,5

1: School of Computation, Information and Technology (CIT), Faculty of Informatics, Chair of Bioinformatics & Computational Biology - i12, Technical University of Munich (TUM), Boltzmannstr. 3, 85748 Garching/Munich, Germany; 2: Institute of Computational Biology (ICB), Helmholtz München, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany; 3: Translational Microbiome Data Integration, School of Life Sciences, Technical University of Munich (TUM), Alte Akademie 8, 85354 Freising, Germany; 4: Institute for Advanced Study (TUM-IAS), Technical University of Munich (TUM), Lichtenbergstr. 2a, 85748 Garching/Munich, Germany; 5: School of Life Sciences Weihenstephan (TUM-WZW), Technical University of Munich (TUM), Alte Akademie 8, 85354 Freising, Germany

Fused Transformer Blocks Improve Pretraining Efficiency and Contextual Language Understanding

Jörn Schmiedel

factorize.bio, Germany

Persona Vectors: Steering Towards Faithful Verbalized Uncertainty Expression in LLMs

Arsen Sheverdin^1,2, Tim G. J. Rudner³, Vincent Fortuin^1,4

1: Helmholtz AI, Munich; 2: Technical University of Munich; 3: University of Toronto; 4: Technical University of Nuremberg

Scalable and interpretable representation alignment with ordinal similarity

Diogo Soares¹, Pankhil Gawade^1,2, Andrea Dittadi¹, Ewa Szczurek^1,3

1: Helmholtz Munich, AIH, Germany; 2: Technical University of Munich, Germany; 3: University of Warsaw, Poland

Multimodal Data-driven Transfer Learning Impelled Framework for Spatiotemporal Forecasting of Urban Pollution (PM2.5)

Narendran Sobanapuram Muruganandam, Erika Von Schneidemesser

Research Institute for Sustainability, Germany

A Hierarchical Bayesian Multiple Instance Learning Framework for Joint Localization and Testing of Spatial Differential Expression

Niklas Stotzem^1,2, Simon Chang³, Na Cai⁴, Francesco Paolo Casale^1,2

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany; 3: Regensburg University, Germany; 4: ETH Zurich, Switzerland

Streamlined Training and Deployment of PEFT Adapters for LLMs in HPC-Cloud Hybrid Environments

Varun Sudharshnam, Tuan Anh Vu, Kushal Ramakrishna, Mani Lokamani, Henrik Schulz, Uwe Konrad

Helmholtz Zentrum Dresden Rossendorf, Germany

Speed or Sophistication? Benchmarking YOLOv11 and VLMs in Intelligent Traffic Systems

Maciej Szymkowski

Future Processing, Poland

Trustworthy Deep Surrogates for Inverse Materials Design with Calibrated Uncertainty

Hui Min Teh¹, Tarek Iraki¹, Stefan Sandfeld^1,2

1: Institute for Advanced Simulations - Materials Data Science and Informatics (IAS-9), Forschungszentrum Jülich GmbH; 2: Chair of Materials Data Science and Materials Informatics, Faculty 5 – Georesources and Materials Engineering, RWTH Aachen University

In-Model Bias Mitigation Methods for Age Confounding in Dementia Detection

Jaya Terli¹, Majid Ramedani¹, Stefan Teipel^1,2, Martin Dyrba¹

1: Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Rostock, Germany; 2: Klinik für Psychosomatische Medizin und Psychotherapie (KPM), Universitätsmedizin Rostock, Germany

Modeling Neuro–Behavioral State Dynamics from Longitudinal Multimodal Recordings

Jens Tillmann¹, Tobias Schmidt², Ziyan Huang¹, Amine Bahlouli¹, Steffen Schneider², Jan Gründemann^1,3

1: Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE), Germany; 2: Helmholtz Munich, Neuherberg, Germany; 3: University of Bonn, Medical Faculty, Bonn, Germany

Consistent Representation Learning for Modeling Neuro-Behavioral State Dynamics

Tobias Schmidt^1,4, Jens Tillmann², Rodrigo González Laiz^1,4, Kristián Szuppinger¹, Ziyan Huang², Amine Bahlouli², Jan Gründemann^2,3, Steffen Schneider^1,4

1: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt ( GmbH ) Germany; 2: German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; 3: University of Bonn, Medical Faculty, Bonn, Germany; 4: Munich Center for Machine Learning

Self-supervised Denoising Of Raw Tomography Detector Data For Improved Image Reconstruction

Israt Jahan Tulin, Sebastian Starke, Dominic Windisch, André Bieberle, Peter Steinbach

Helmholtz-Zentrum Dresden - Rossendorf e. V., Germany

Machine Learning-Guided Discovery of Small Molecule Inhibitors Targeting PD-L1 for Cancer Immunotherapy

Hunzallah Usmani^1,2, Wim Dehaen²

1: Middle East Technical University (Türkiye); 2: University of Chemistry and Technology, Prague (Czechia)

An HPC-Based Kubernetes Cluster for Next-Generation Scientific Computing

Tuan Anh Vu¹, Varun Sudharshnam¹, Mani Lokamani¹, Daniel Kotik¹, Michael Bussmann^1,2, Henrik Schulz¹, Uwe Konrad¹

1: Helmholtz-Zentrum Dresden-Rossendorf, Germany; 2: Center for Advanced Systems Understanding (CASUS)

Semantic Harmonization of Noisy Medical Imaging Cohorts via Vision-Language Model

Xiaoliang Wang¹, Jiayi Wang¹, Ibrahim Ethem Hamamci^3,4,5, Suprosanna Shit^3,4, Sezgin Er^3,5, Hadrien Reynaud¹, Weitong Zhang², Bjoern Menze^3,4, Andreas Maier¹, Bernhard Kainz^1,2

1: Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany; 2: Imperial College London, UK; 3: University of Zurich, Switzerland; 4: ETH Zurich, Switzerland; 5: Istanbul Medipol University, Turkey

Enhancing Clinical Immunology and Disease Diagnostics with Global Swarm Learning

Stefanie Warnat-Herresthal¹, Ivan Savchuk¹, Lucas Secchim Ribeiro¹, Benedikt Clemens¹, Kilian Dahm¹, Maren Büttner², Hartmut Schultze^1,3, Matthias Becker¹, Lorenzo Bonaguro¹, Global Swarm Learning Group⁴, Anna Aschenbrenner¹, Joachim L. Schultze¹

1: DZNE, Germany; 2: Calico Life Sciences; 3: Hewlett Packard Enterprise, Houston, Texas, USA; 4: The Global Swarm Learning Group

Flow-aware Latent Diffusion for Synthetic Temporal Angiography

Qiwen Xu^1,2, Andreas Bender¹, Máté Maros², David Rügamer¹

1: LMU Munich, Germany; 2: Heidelberg University, Germany

MatBind: Probing the multimodality of materials science with contrastive learning

Le Yang¹, Anoop K. Chandran⁹, Jona Östreicher³, Adrian Mirza², Sebastien Bompas¹, Bashir Kazimi¹, Stefan Kesselheim^9,4, Pascal Friederich³, Kevin Maik Jablonka^2,6,7,8, Stefan Sandfeld^1,5

1: Institute for Advanced Simulations (IAS-9), Forschungszentrum Jülich GmbH, Germany; 2: Helmholtz Institute for Polymer in Energy Applications Jena, Germany; 3: Institute of Nanotechnology, Karlsruhe Institute of Technology, Germany; 4: University of Cologne, Germany; 5: RWTH Aachen University, Germany; 6: Friedrich Schiller University Jena, Germany; 7: Jena Center for Soft Matter, Germany; 8: Center for Energy and Environmental Chemistry Jena, Germany; 9: Jülich Supercomputing Centre, Forschungszentrum Jülich GmbH, Germany

Creating a Benchmark Image Dataset for Reliable Quantification of Arctic Phytoplankton using AI

Anna Narberhaus¹, Natasha Bryan¹, Mar Fernández-Méndez^1,2

1: Alfred-Wegener-Institut, Germany; 2: University of Bremen, Germany

PromptGate: Federated Context Optimizationfor Dynamic VLM Gating in Open-Set MedicalImaging

Adea Nesturi, David Duenas Gaviria, Jiajun Zeng, Shadi Albarqouni

University of Bonn, University Hospital Bonn, Clinic for Diagnostic and Interventional Radiology, Bonn, Germany

Neural Posterior Estimation for Empirical Power System Time Series

Ulrich Oberhofer, Nicolas Weber, Veit Hagenmeyer, Benjamin Schäfer

Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology, Germany

Underconfident Predictions in MFVI

James Odgers, Vincent Fortuin

Helmholtz Munich, Germany

Differentiable Power-Flow Optimization

Muhammed Öz¹, Jasmin Hörter¹, Kaleb Phipps¹, Charlotte Debus¹, Achim Streit¹, Markus Götz^1,2

1: Karlsruhe Institute of Technology, Germany; 2: Helmholz AI, Karlsruhe

A generative model for dimensionality reduction with millions of features and few samples

Corrado Pancotti¹, Anders Krogh², Piero Fariselli³

1: Helmholtz AI, Helmholtz Zentrum Munchen, Ingolstadter Landstraße 1,Neuherberg, Germany; 2: Center for Health Data Science, Department of Public Health, University of Copenhagen, Copenhagen, Denmark; 3: Department of Medical Sciences, University of Torino, Italy

"Hello World": How to Have a Conversation with the Global Weather

Kaleb Phipps¹, Hannes Gaumann¹, Friedrich Oberreuter¹, Akshat Vyas¹, Christian Werner¹, Jonathan Winter¹, Charlotte Debus¹, Markus Götz^1,2, Paul Kieckhefen^1,2

1: Karlsruhe Institute of Technology, Germany; 2: Helmholtz AI

Segmentation of the intracranial cavity in T1-weighted MR images of the human head by a location-specific 3D U-Net

Peter Pieperhoff¹, Svenja Caspers^1,3, Katrin Amunts^1,2

1: Institute for Neuroscience and Medicine (INM-1), Forschungszentrum Jülich, Germany; 2: C. and O. Vogt Institute for Brain Research, Medical Faculty, University Hospital, Heinrich-Heine-University of Düsseldorf, Germany; 3: Institute for Anatomy I, Medical Faculty, University Hospital, Heinrich-Heine-University of Düsseldorf, Germany

BioCUDA: An Accessible AI Pipeline for Fast, Accurate 3D MRI Reconstruction Across Species

Stefan Pinkernell¹, Karsten Schimpf¹, Felizitas Wermter², Karol Szustakowski³, Marie Piraud³, Christian Bock², Sonja Hänzelmann¹

1: Data Science Group, Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research, Bremerhaven; 2: Integrative Ecophysiology, Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research, Bremerhaven; 3: Piraud Team, Helmholtz AI, Helmholtz Munich

Machine-Learned Interatomic Potentials for Fe–Ni Alloys: Benchmarking MACE Models for Magnetism and Phase Stability

Kushal Ramakrishna¹, Mani Lokamani¹, Attila Cangi^1,2

1: Helmholtz-Zentrum Dresden-Rossendorf (HZDR); 2: Center for Advanced Systems Understanding (CASUS)

Hybrid Multimodal Late Fusion Frameworks for Robust bvFTD Classification in Imbalanced Dementia Cohorts

Majid Ramedani¹, Devesh Singh^1,2, Stefan Teipel^1,3, Martin Dyrba¹

1: German Center for Neurodegenerative Diseases (DZNE), Germany; 2: Institute and Policlinic of Radiology, Pediatric Radiology and Neuroradiology, University Medical Center Rostock, Rostock, Germany; 3: Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany

Amortising Inference and Meta-Learning Priors in Neural Networks

Tommy Rochussen^1,2,3, Vincent Fortuin^1,2,4

1: Helmholtz AI, Germany; 2: MCML, Germany; 3: TUM, Germany; 4: UTN, Germany

SCHEMA: profiling Spatial Cancer HEterogeneity across modalities to benchmark Metastasis risk prediction

Daria Romanovskaia^1,2, Nikita Moshkov¹, Niklas Binder³, Mohammed Zidane^1,3, Fabian Theis^1,5,6, Carsten Weiss⁴, Christian Schuerch³, Markus Diefenbacher², Malte Luecken^1,2

1: Institute of Computational Biology, Helmholtz Munich, Germany; 2: Institute of Lung Health and Immunity, Helmholtz Munich, Germany; 3: University Hospital Tübingen, Germany; 4: Karlsruhe Institute of Technology, Germany; 5: TUM School of Life Sciences Weihenstephan,Technical University of Munich, Germany; 6: TUM School of Computing, Information and Technology, Technical University of Munich, Munich, Germany

Machine Learning-Accelerated Prediction of Hydrogen Embrittlement fromTEM Microstructures

Karina Ruzaeva¹, Aravinth Ravikumar², Bashir Kazimi¹, Daniel Höche², Stefan Sandfeld¹

1: Forschungszentrum Juüich GmbH; 2: Helmholtz Zentrum Hereon, Germany

Multimodal Data-Driven Forecasting of Coastal Environmental Health in the Baltic Sea

Naina Said¹, Helmke Hepach², Olaf Landsiedel³, Laura Harms³

1: Christian-Albrechts-Universität zu Kiel (CAU), Germany; 2: GEOMAR Helmholtz Centre for Ocean Research Kiel, Germany; 3: Technische Universität Hamburg, Germany

LieAugmenter: Equivariant Learning by Discovering Symmetries with Learnable Augmentations

Eduardo Santos-Escriche^1,2, Ya-Wei Eileen Lin^1,2, Stefanie Jegelka^1,2,3,4

1: Technical University of Munich (School of CIT); 2: Munich Center for Machine Learning; 3: Munich Data Science Institute; 4: MIT (Department of EECS and CSAIL)

Improvement of Whale Vocalization Detection with Temporal Context and Soft Labels

Alex Savchik¹, Stefan Pinkernell¹, Elena Schall², Sonja Haenzelmann¹

1: Data Science Group, Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research, Germany; 2: Ocean Acoustics Group, Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research

Learning Coarse-Grained Potentials for Intrinsically Disordered Proteins

Moritz Schäffler, Emil de Bruyn, Sebastian Schmidt, Stefan Kesselheim

Forschungszentrum Jülich, Germany

A modular Retrieval Augmented Generation (RAG) Toolbox for Building Transparent AI-Search Engines

Mascha Schmidt, Victor Haguet, Fritz Niesel

FZJ, Germany

Better Uncertainties Don’t Guarantee Better Decisions

Annika Schneider^1,2,3,4, Tommy Rochussen^1,2,4, Vincent Fortuin^1,2,3,4

1: HAI, Germany; 2: TUM; 3: relAI; 4: MCML

Attributing the effects of multiple line outages via Shapley values

Sarah Schreyer¹, Marc Hunkemöller¹, Jan Lange¹, Iva Bačić¹, Philipp C. Böttcher¹, Dirk Witthaut¹, Johannes Kruse²

1: Institute of Climate and Energy Systems (ICE-1), Forschungszentrum Jülich, Germany; 2: Amprion GmbH, Transmission System Operation, Germany

Can Uncertainty Quantification Benefit From Label Embeddings? A Case Study on Local Climate Zone Classification

Christoph Schweden¹, Katharina Hechinger², Göran Kauermann³, Xiao Xiang Zhu⁴

1: German Aerospace Center, Germany; 2: Interhyp; 3: LMU Munich; 4: TUM

A mamba-accelerated digital twin for near-real-time prediction in Geolab

Mrityunjay Singh^1,2, Markus Bleicher^1,2, Alankar Kumarmangalem Kamble^1,3, Hema Priya Rajangam^1,3, Fiorenza Deon¹, Ingo Sass^1,2

1: Section 4.3 Geoenergy Section, GFZ Helmholtz Centre for Geosciences; 2: Institute of Applied geosciences, Technical University of Darmstadt; 3: Department of Astrophysics, University of Potsdam

Benchmarking Taxonomic Classifiers: Bridging 16S rRNA metabarcoding and Shotgun Metagenomics for AI-Driven Microbiome Decoding

Sakshi Singh^1,2, Florian Heininger^1,2, Xu Holtkotte^1,2, Sabine Schmidt⁴, Jens Puschhof⁵, Eran Elinav^6,4, Silke A. Grauling-Halama^1,2, Niels Halama^1,2,3

1: Department of Tumor Immunology and Tumor Immunotherapy, Helmholtz Center for Translational Oncology (HI-TRON), Mainz, Germany; 2: German Cancer Research Center (DKFZ), Heidelberg, Germany; 3: Department of Hematology, Medical Oncology and Pneumology, University Medical Center, Mainz, Germany; 4: Division of Microbiome and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany; 5: Epithelium Microbiome lnteractions, German Cancer Research Center (DKFZ), Heidelberg, Germany; 6: Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel

Toward Condition-Aware MOF Topology Prediction via Latent Generative Modeling

Evgenii Sovetkin¹, Gordan Prastalo², Stefan Kesselheim¹, Kevin Maik Jablonka²

1: Forschungszentrum Jülich GmbH, Germany; 2: Helmholtz Institute for Polymers in Energy Applications Jena (HIPOLE Jena), Jena, Germany

Blur-aware Single-cell Segmentation and Feature Extraction for Drug-activity Measurement in Brightfield Organoid Imaging

Serena Sritharan¹, Fatima Gutierrez Tenorio^2,3, Claudia Ball^2,3, Marie Piraud¹

1: Helmholtz Zentrum München GmbH, Germany; 2: Department for Translational Medical Oncology, NCT/UCC Dresden and DKFZ; 3: Translational Medical Oncology, Carl Gustav Carus Faculty of Medicine, Dresden

Decoding Values: Measuring Culture Embedded in Large Language Models

Anton Steuer^1,2, Carolin Schuster², Michael Banf¹

1: Perelyn GmbH, Germany; 2: Technical University Munich, Germany

Cytoarchitecture in Words: Weakly Supervised Vision–Language Modeling for Human Brain Microscopy

Matthew Sutton^1,2, Katrin Amunts^1,3, Timo Dickscheid^1,4, Christian Schiffer^1,2

1: Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Germany; 2: Helmholtz AI, Research Centre Jülich, Germany; 3: Cécile & Oskar Vogt Institute for Brain Research, University Hospital Düsseldorf, Germamny; 4: Computer Vision, Institute for Computational Visualistics, University of Koblenz, Germany

The (AI)^2 Consultant - A Co-consultant for AI Consultants

Karol Szustakowski, Haider Khan, Marie Piraud

Helmholtz Zentrum Munich, Germany

Accessible pipeline for open set dermatological captioning with scarce data

Karol Szustakowski¹, Sebastian Sitaru², Paola Buedo¹, Marie Piraud¹

1: Helmholtz AI, Helmholtz Zentrum München, Germany; 2: Technical University of Munich, Klinikum rechts der Isar, Germany

Machine Learning for Rogue Wave Prediction in the Southern North Sea

Salika Thilakarathne¹, Ina Teutsch², Lisa Barros de Andrade e Sousa³, Paul Keil^1,3, Marie Piraud³, Ralf Weisse¹

1: Helmholtz-Zentrum Hereon, Germany; 2: Federal Waterways Engineering and Research Institute (BAW); 3: Helmholtz AI

Nanopore- and AI-Empowered Microbial Viability Inference

Harika Muazzez Ürel

Helmholtz Munich, Germany

Counterfactual Ship Attribution in Cloud Fields Using Deep Learning and Satellite Observations

Rikard Vinge, Athina Argyrouli, Daniela Espinoza-Molina, Pascal Hedelt

German Aerospace Center (DLR), Germany

RenewBench: Real Energy Data You Can Actually Use

Elena Vollmer^1,3, Andreas Beckert^2,3, Hadeer El Ashhab^1,3, Paul Keil^2,3, Benjamin Schäfer^1,3, Beate Geyer^2,3, Markus Götz^1,3, Tobias Weigel^2,3, Kaleb Phipps¹

1: Karlsruhe Institute of Technology (KIT), Germany; 2: Helmholtz-Center Hereon, Germany; 3: Helmholtz AI, Germany

Are Reasoning LLMs Robust to Interventions on Their Chain-of-Thought?

Alexander von Recum^1,3, Leander Girrbach^1,2, Zeynep Akata^1,2

1: Helmholtz AI, Germany; 2: Technical University of Munich, Germany; 3: Ludwig Maximilian University of Munich, Germany

An AI System for Robust Plain Language Translation of Clinical Trials

Raeesa Yousaf^1,2, Stephanie Stapfer², Sebastian Lobentanzer^1,2

1: Institute of Computational Biology, Computational Health Center, Helmholtz Munich, Germany; 2: German Center for Diabetes Research, Germany

K-MaT: Knowledge-Anchored Manifold Transport For Cross-Modal Prompt Learning In Medical Imaging

Jiajun Zeng^1,2, Shadi Albarqouni^1,2

1: University Hospital Bonn, Germany; 2: University of Bonn, Germany

Analysis of immune responses in renal cell carcinoma with synergistic ex vivo and in silico simulation tumor models

Xin-Wen Zhang^1,2, Alexandra Poechmann^1,3, Elena Sofia Rießle¹, Stefanie Zschäbitz⁴, Matthias Gaida⁵, Niels Halama^1,6

1: German Cancer Research Center (DKFZ), Helmholtz Institute for Translational Oncology (HI-TRON), Tumor Immunology and Tumor Immunotherapy, Mainz, Germany; 2: University Medical Center Mainz, Department of Hematology and Medical Oncology, Mainz, Germany; 3: Faculty of Biosciences, Ruprecht Karls University, Heidelberg, Germany; 4: National Center for Tumor Diseases, Department of Medical Oncology, Heidelberg, Germany; 5: University Medical Center Mainz, Institute for Pathology, Mainz, Germany; 6: University Medical Center Mainz, University Cancer Center (UCT), Mainz, Germany

Bad Data Detection and Signal Recovery in Large-Scale ICT-Platforms

Marcel Zimmer¹, Maximilian Büchel¹, Daniele Carta¹, Andrea Benigni^1,2,3

1: ICE-1, Institute of Climate and Energy Systems, Forschungszentrum Jülich, 52428 Jülich, Germany; 2: RWTH Aachen University, Aachen 52056, Germany; 3: JARA-Energy, Jülich 52425, Germany

System Characterization by Affine Operators in Physics-Informed Gaussian Processes

Marcel Zimmer¹, Edoardo De Din¹, Daniele Carta¹, Andrea Benigni^1,2,3

1: ICE-1, Institute of Climate and Energy Systems, Forschungszentrum Jülich, 52428 Jülich, Germany; 2: RWTH Aachen University, Aachen 52056, Germany; 3: JARA-Energy, Jülich 52425, Germany

A Neural Operator Framework for Particle-based Kinetic Plasma Simulations

Sriramkrishnan Muralikrishnan¹, Chelsea John¹, Jeffrey Kelling², Paul Gibbon¹, Michael Bussmann²

1: Forschungszentrum Jülich GmbH, Germany; 2: Helmholtz Zentrum Dresden-Rossendorf, Germany

Learning PDE Dynamics from Small Data: Out-of-Distribution Generalization of Deep Learning Surrogates

Binh Duong Nguyen¹, Stefan Sandfeld^1,2

1: Institute for Advanced Simulations -- Materials Data Science and Informatics (IAS-9), Forschungszentrum Juelich GmbH, Juelich 52425, Germany; 2: Chair of Materials Data Science and Materials Informatics, Faculty 5 -- Georesources and Materials Engineering, RWTH Aachen University, Aachen 52056, Germany

Human-Explainable, Compact, Clustering-based Latents for Fast Proton Energy Spectra Estimation

Vedhas Pandit¹, Jeyhun Rustamov¹, Martin Rehwald¹, Stefan Assenbaum^1,3, Vidisha Rana¹, Hans-Peter Schlenvoigt¹, Michael Bussmann^1,2, Ulrich Schramm^1,3, Thomas Kluge¹, Jeffrey Kelling^1,4

1: Helmholtz-Zentrum Dresden-Rossendorf e.V., Germany; 2: Center for Advance Systems Understanding (CASUS), Görlitz, Saxony, Germany; 3: TUD Dresden University of Technology, 01062 Dresden, Germany; 4: Technische Universität Chemnitz, Institute of Physics, Chemnitz, Saxony, Germany

Collaborative Research Data Management for AI

René Peinl, Vincent Tischler

Hof University of Applied Sciences, Germany

From FAIR Multimodal Data Infrastructure to AI-Driven Clinical Interpretation: The MINDset Platform for Precision Psychiatry

Ravichandran Rajkumar^1,2, Syed Muhammad Ali^1,2, Edward Kempa^1,3, Markus Zimmermann^1,4, N Jon Shah^1,5, Irene Neuner^1,2,6

1: Institute of Neuroscience and Medicine 4 (INM-4), Forschungszentrum Jülich GmbH, Jülich, Germany; 2: Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Aachen,RWTH Aachen University, Aachen, Germany; 3: Department of Computer and Information Science and Engineering, University of Florida, USA; 4: Faculty of Medical Engineering and Technomathematics, FH Aachen University Applied Sciences, Aachen, Germany; 5: Department of Neurology, RWTH Aachen University, Aachen, Germany; 6: Department of Psychiatry II, Ulm University and BKH Günzburg, Germany.

GENOVA: A framework for statistical validation of generative networks in high-dimensional scientific data.

Humberto Reyes Gonzalez¹, Marco Letizia², Gaia Grosso³, Riccardo Torre⁴, Samuele Grossi², Raffaello Biagini⁵, Pietro Cappelli⁶

1: RWTH Aachen, Germany; 2: University of Genoa, Italy; 3: Massachusetts Institute of Technology, USA; 4: INFN, Sezione di Genova, Italy; 5: University of Pisa, Italy; 6: Brandeis University, USA

Measuring Diversity in Multi-Agent Motion Generation

Christian Schlauch^1,2, Nadja Klein¹

1: Karlsruhe Institute of Technology, Germany; 2: Aumovio SE

GEOMAGFOR - Geomagnetic Core Field Forecasting: Excursions and Polarity Reversals

Jan Simkanin¹, Martin Rother², Andre Giesecke¹, Ingo Michaelis², Monika Korte², Frank Stefani¹

1: Institute of Fluid Dynamics, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Germany; 2: Geomagnetism, GFZ Helmholtz Centre for Geosciences, Potsdam, Germany

Clinical Evidence to Individualized Care: AI Powered Clinical Decision Support Based on Predicted Individual Treatment Effect (PITE)

Pamela Solano¹, Thomas Jaki^1,2

1: Faculty for Informatics and Data Science, Regensburg University, Germany; 2: MRC Biostatistics Unit, University of Cambridge, UK

Integrating an LLM Chatbot into an Existing Web Frontend via DASF and MCP

Philipp S. Sommer, Naseem Ali, Beate Geyer, Harsh Grover, Johannes Schulz-Stellenfleth

Helmholtz-Zentrum Hereon, Germany

CapTrack: Multifaceted Evaluation of Forgetting in LLM Post-Training

Lukas Thede^1,2,3, Stefan Winzeck¹, Zeynep Akata^3,4, Jonathan Richard Schwarz^1,5

1: Thomson Reuters Foundational Research; 2: Tübingen AI Center, University of Tübingen; 3: Helmholtz Munich; 4: MCML, Technical University of Munich; 5: Imperial College London

Patch-MLP-Based Predictive Control: Simulation of Upstream Pointing Stabilization for PHELIX Laser System

Jiaying Wang¹, Jonas Benjamin Ohland², Yen-Yu Chang³, Vedhas Pandit¹, Stefan Bock¹, Andrew-Hiroaki Okukura^4,5,6, Udo Eisenbarth², Arie Irman¹, Michael Bussmann¹, Ulrich Schramm^1,7, Jeffrey Kelling^1,8

1: Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; 2: GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany; 3: Amplitude laser group—Dresden operations, Dresden, Germany; 4: Extreme Light Infrastructure—Nuclear Physics, National Institute for Physics and Nuclear Engineering, Ilfov, Romania; 5: University of Bucharest, Ilfov, Romania; 6: Engineering and Applications of Lasers and Accelerators Doctoral School (SDIALA), National University of Science and Technology Politehnica of Bucharest, Bucharest RO-060042, Romania; 7: Technische Universität Dresden, Dresden, Germany; 8: Chemnitz University of Technology, Chemnitz, Germany

Promise and Limitations of Learning the Morphological Representations of Life

Artur Yakimovich

Helmholtz Center Dresden-Rossendorf, Germany

Evaluating 3D Molecular Representation Learning with Multipolar Atom Types

Jan Olszewski¹, Marta Kulik¹, Anna Gambin¹, Ewa Szczurek^1,2

1: University of Warsaw; 2: Helmholtz Munich

AI-enabled Colorimetric Multi-Biomarker Sensing Patch for Neonatal Monitoring

Alejandra Castelblanco^1,2, Elisabetta Ruggeri³, Giusy Matzeu³, Motaharehsadat Heydarian⁴, Kai Foerster^4,5, Ahmed Bahnasy², Andreas Flemmer⁵, Julia A. Schnabel^1,2,6, Benjamin Schubert¹, Fiorenzo G. Omenetto^3,8,9, Anne Hilgendorff^4,5,7

1: Computational Health Center, Helmholtz Center Munich, Neuherberg, Germany.; 2: School of Computation, Information and Technology, Technical University of Munich, Munich, Germany.; 3: Silklab, Dept. of Biomedical Engineering, Tufts University, Medford, MA, USA.; 4: Comprehensive Pneumology Center with the CPC-M bioArchive and Institute of Lung Health and Immunity, Helmholtz Center Munich, Member of the German Center of Lung Research (DZL), Munich, Germany; 5: Dr. von Hauner Children’s Hospital, Hospital of the Ludwig-Maximilians-Universität München, Munich, Germany; 6: School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK.; 7: School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany; 8: Dept. of. Electrical and Computer Engineering, Tufts University, Medford, MA, USA.; 9: Dept. Of Physics, Tufts University, Medford, MA, USA.

Implicit Neural Representation (INR) meets Multi-Contrast MRI Reconstruction

Natascha Niessen^1,2, Carolin M. Pirkl², Ana Beatriz Solana², Hannah Eichhorn^1,3, Veronika Spieker^1,3, Wenqi Huang¹, Tim Sprenger^2,4, Marion I. Menzel^2,5,6, Julia A. Schnabel^1,3,7, Predictom Consortium²

1: School of Computation, Information and Technology, Technical University of Munich, Munich, Germany; 2: GE HealthCare, Munich; 3: Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich; 4: Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; 5: Technische Hochschule Ingolstadt, Ingolstadt, Germany; 6: School of Natural Sciences, Technical University of Munich, Munich, Germany; 7: King’s College London, London, United Kingdom

Deep Learning Reconstruction of Diffusion Spectrum Imaging from Undersampled q-Space Measurements

Roman Schmid¹, Sebastian Endt^1,2, Marion I. Menzel^1,2

1: Technische Hochschule Ingolstadt, Germany; 2: Technical University of Munich, Germany

HematoGraph: Graph-Aware Hierarchical Pooling for Cell-Level Hematology Classification

Furkan Dasdelen^1,3, Fatih Ozlugedik^1,2,3, Carsten Marr^1,3

1: Helmholtz Munich, Germany; 2: TUM; 3: LMU

Contour Proposal Networks with Deep Refinement for Dense High-Throughput Instance Segmentation

Eric Upschulte^1,2,3, Katrin Amunts^2,1, Timo Dickscheid^4,2,3

1: C. & O. Vogt Institute for Brain Research, University Hospital Düsseldorf, Germany; 2: Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Germany; 3: Helmholtz AI, Research Center Jülich, Germany; 4: Institute for Computational Visualistics, University of Koblenz, Germany

Tiamat: Tiled Image Access, Manipulation, and Analysis Toolkit for Visualization and Analysis of Large Scientific Image Datasets

Christian Schiffer^1,2, Alexander Oberstrass^1,2, Julia Thönnißen¹, Xiao Gui¹, Jan-Oliver Kropp^1,2,3, Felix Matuschke¹, Tobias Salz¹, Markus Axer^1,4, Katrin Amunts^1,3, Timo Dickscheid^1,2,5

1: Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany; 2: Helmholtz AI, Research Centre Jülich, Jülich, Germany; 3: Cécile & Oskar Vogt Institute of Brain Research, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany; 4: Department of Physics, University of Wuppertal, Wuppertal, Germany; 5: Institute for Computational Visualistics, Faculty of Computer Science, University of Koblenz, Koblenz, Germany

MLArray: Unifying Machine Learning-Optimized Array Storage and Imaging Metadata

Karol Gotkowski, Kris Dreher

German Cancer Research Center (DKFZ), Germany

Microsecond Latency Graph Neural Network Inference on Point Clouds

Marc Neu, Torben Ferber, Jürgen Becker

Karlsruhe Institute of Technology, Germany

GENIUS: An Agentic AI Framework for Autonomous Design and Execution of Simulation Protocols

Celso Rêgo¹, Mohammad Soleymanibrojeni², Wolfgang Wenzel¹, Roland Aydin²

1: Karlsruhe Institute of Technology, Germany; 2: Helmholtz-Zentrum Hereon

The Road to Exascale: Lessons Learned from Scaling a Scientific AI Workflow to 16,384 GPUs

Christian Schiffer^1,2, Julia Thönnißen¹, Mathis Bode³, Josh Moore⁴, Katrin Amunts^1,5, Timo Dickscheid^1,2,6

1: Institute of Neuroscience and Medicine (INM-1), Forschungszentrum Jülich (FZJ), Germany; 2: Helmholtz AI, Forschungszentrum Jülich (FZJ), Germany; 3: Jülich Supercomputing Centre (JSC), Forschungszentrum Jülich, Germany; 4: German BioImaging, Gesellschaft für Mikroskopie und Bildanalyse e.V, Konstanz, Germany; 5: Cécile & Oskar Vogt Institute for Brain Research, University Hospital Düsseldorf, Germany; 6: Computer Vision, Institute for Computational Visualistics, University of Koblenz, Germany

Video-Guided Policies for Robotic Manipulation

Cordelia Schmid

Inria, France

Helmholtz Munich: Discovering Future Health

Eleftheria Zeggini

Helmholtz Munich, Germany

Translational Genomics of Osteoarthritis

Eleftheria Zeggini

Helmholtz Munich, Germany

Biophysics-Informed and AI-Assisted Computation for Translational Optoacoustic Imaging and Sensing

Dominik Jüstel^1,2

1: Helmholtz Munich, Germany; 2: Technical University of Munich, Germany

From Multivariate Perturbations to Predictive Models of Human Airway Function

Katzrin Murad, Benedetta Zampa, Weixu Wang, Inti De La Rosa Velázquez, Fabian Theis, Janna Nawroth

Helmholtz Zenter München GmbH, Germany

The Interaction Layer: Why the Virtual Cell Needs Biochemistry

Pascal Falter-Braun

Helmholtz Munich, Germany