Opening remarks

Guido Iaccarino¹, Daniele Vignoli²

1: Federico II University, Italy; 2: University of Florence, Italy

Institutional greetings

Fabrizio Cobis

Ministero dell’Università e della Ricerca, Italy

Living Better, Working Longer: Adapting Labour Markets to an Ageing Population

Angelica Salvi del Pero

OECD - Organization for Economic Co-operation and Development, Italy

Keynote Speaker

Alfonso Jose Cruz Jentoft

Ramón y Cajal University Hospital, Madrid, Spain

Reference to Mental vs. Physical Health in a Messaging Intervention to Promote Physical Activity in Adults Over 50

Patrizia Catellani, Valentina Carfora, Marco Gaetani, Laura Picciafoco

Catholic University of the Sacred Heart, Milan, Italy

Understanding Depression in Old Age: Initial Findings from a Longitudinal Study of Psychological, Social and Behavioral Factors

Laura Picciafoco, Catellani Patrizia, Barbiani Diletta, Bellocchio Virginia, Cisotto Elisa, Mauri Alice, Marchetti Antonella, Valle Annalisa, Graffigna Guendalina, Savarese Mariarosaria, Villani Daniela, Pancini Elisa, Cremaschi Giulia, Castelnuovo Gianluca, Antonietti Alessandro, Pagnini Francesco

Università Cattolica del Sacro Cuore, Italy

The built environment in the multilevel person-centered design approach. Housing as a tool for health promotion in the life-course perspective.

Erminia Attaianese, Mariangela Perillo

University of Naples Federico II, Italy

Unraveling Functional Decline: The Relationship between Muscle Strength and Ultrasound Evaluation of Biceps Brachii Thickness

Klara Komici¹, Maria Chiara Brunese¹, Giuseppe Rengo², Germano Guerra¹

1: University of Molise, Italy; 2: University of Naples, Federico II

Decoding aging pathways: Insights from the Novara Cohort Study, a population-based initiative in Piedmont

Daniela Capello¹, Giulia Garro¹, Silvia Cracas¹, Jacopo Venetucci¹, Luca Briacca¹, Valentina Bettio¹, Roberta Rolla², Annamaria Antona¹, Fabrizio Faggiano³

1: DIMET, University of Eastern Piedmont, Italy; 2: DISS, University of Eastern Piedmont, Italy; 3: DISSTE, University of Eastern Piedmont, Italy

Public and private solutions for long-term care insurance: coping with frailty and dependence

Asya Bellia¹, Valeria Bellini², Agar Brugiavini³, Raluca Elena Buia³, Diego Ciccone², Silvia D'Arrigo³, Vincenzo Galasso¹, Francesco Geremia², Federica Martinelli², Chiara Signorello²

1: Bocconi University; 2: Generali Italia; 3: Ca' Foscari University of Venice

Who (and why) is still afraid of Reverse Mortgages? Results from survey in Italy

Beatrice Bertelli¹, Emilia Di Lorenzo², Alba Roviello², Costanza Torricelli^1,3,4

1: University of Modena and Reggio Emilia, Italy; 2: University of Naples Federico II, Italy; 3: CeRP; 4: Cefin

Clarifying Healthy Ageing: Building a Common Language for Policy Innovation within the AGE-IT project

Fulvio Ricceri^1,2, Alberto Catalano^1,2, Gregory Winston Gilcrease¹, Alessandra Macciotta¹, Lorenzo Milani¹, Gianluca Aimaretti², Aleksandra Torbica³, Savino Sciascia¹

1: University of Turin, Italy; 2: University of Eastern Piedmont, Italy; 3: Bocconi University, Italy

Supply of Tertiary Education and Individuals' Labor Market Outcomes

Ylenia Brilli¹, Elena Cottini², Paolo Ghinetti³, Gloria Moroni¹

1: Ca' Foscari University of Venice, Italy; 2: Catholic University Milan, Italy; 3: University Easter Piedmont, Italy

Trust as a wealth management and estate planning tool for older adults

Maria Epifania

Università degli Studi del Molise, Italy

Enhancing Physical Activity in Older Adults Through AI: A Pilot Study of a Mobile App with 3D Motion Tracking

Carlo della Valle^1,2, Giulia Di Martino¹, Gloria Di Claudio^1,2, Alessio Mellis¹, Giovanni Fiorilli¹, Alessandra Di Cagno^3,4, Giuseppe Calcagno¹

1: Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy; 2: Department of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy; 3: Department of Movement, Human and Health Sciences, University of Rome “Foro Italico”,Rome, Italy; 4: Department of Human Sciences, Guglielmo Marconi University, Rome, Italy

Comprehensive public health protection for an aging population

Alessandra Buja, Giulia Grotto

Università di Padova, Italy

Organized breast cancer screening programs and unequal access to care: Evidence for the SHARELIFE

Martina Celidoni, Nita Handastya, Guglielmo Weber, Nancy Zambon

University of Padua, Italy

How to Communicate Climate Change Related Issues to Policymakers: A Systematic Review and Metasummary

Marta Massei¹, Diego Longo¹, Alessio Faralli², Leonardo Tellini³, Agnese Andaloro³, Michele Piazzini¹, Chiara Castagnoli², Samuele Pinna¹, Marco Baccini², Francesca Cecchi^1,2

1: Department of Experimental and Clinical Medicine, University of Florence, Italy; 2: Fondazione don Carlo Gnocchi, Scientific Institute, Florence; 3: Specialization School of Physical and Rehabilitation Medicine, University of Florence, Italy

Patient-Reported Outcome Measures (PROMs) in Type 2 Diabetes: Tools, Clinical Use, and Risk Stratification

Rossella Messina¹, Maria Pia Fantini¹, Paolo Di Bartolo^1,2, Rabih Chattat³, Jacopo Lenzi¹

1: Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum-University of Bologna; 2: Ravenna Diabetes Center, Department of Specialistic Medicines, Local Health Agency of Romagna; 3: Department of Psychology, Alma Mater Studiorum-University of Bologna

Frailty in Older Adults: Definitions, Data, Measures, and Tools for Research and Public Health

Giovanna Boccuzzo

University of Padova, Italy

Biomarkers of age-related diseases: studying Alzheimer’s Disease through an integrative serum metabolomic and lipoproteomic NMR-based approach

Alessia Vignoli¹, Giovanni Bellomo², Federico Paolini Paoletti³, Claudio Luchinat⁴, Lucilla Parnetti³, Leonardo Tenori¹

1: University of Florence, Italy; 2: Link Campus University, Italy; 3: University of Perugia, Italy; 4: Giotto Biotech, S.R.L., Italy

Differential Responses of Human Astrocytes to Amyloid β1-42 Treatment: a comparative study between astrocytes from healthy individuals and Alzheimer's patients

Sara Ristori, Elisa Bientinesi, Gianmarco Bertoni, Alessandra Bigi, Daniela Monti

Department of Experimental and Clinical Biomedical Sciences, University of Florence, Italy

Gemcitabine-Induced Astrocyte Senescence: Different Responses in Alzheimer’s Disease vs. Healthy Cells

Gianmarco Bertoni, Sara Ristori, Elisa Bientinesi, Daniela Monti

University of Florence, Italy

The blood molecular signature of progressive carotid stenosis: the ongoing validation phase.

Chiara Bontempo¹, Lucio Publio Gallo¹, Marco Mattiacci², Enrico Giampieri¹, Sabrina Valente^1,2, Annalisa Astolfi^1,2, Gaetano La Manna^1,4, Gianandrea Pasquinelli^1,3, Mauro Gargiulo^1,5, Miriam Capri¹

1: DIMEC- Dipartimento di Scienze Mediche e Chirurgiche, Alma Mater Studiorum-Università di Bologna, Italy; 2: IRCCS-AOU, Bologna, Italy; 3: Pathology Unit, IRCCS-AOU, Bologna, Italy; 4: Nephrology, Dialysis and Renal Transplant Unit, IRCCS-AOU, Bologna, Italy; 5: Vascular Surgery Unit, IRCCS-AOU Bologna, Italy

The potential of a telomere-targeted therapy on lifespan and healthspan of geriatric mice

Maria Elisa Giuliani¹, Giorgia Bigossi¹, Giovanni Lai¹, Serena Marcozzi¹, Fiorenza Orlando¹, Beatrice Bartozzi¹, Andrea Piccinini¹, Davide Perini¹, Sunday Segun Alimi¹, Alessia Oppezzo², Francesca Rossiello², Sara Sepe², Fabrizio d'Adda di Fagagna^2,3, Marco Malavolta^1,4

1: Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, 60121 Ancona, Italy; 2: IFOM, the FIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy; 3: Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (IGM-CNR), Via Abbiategrasso 207, 27100 Pavia, Italy; 4: Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Via Tronto 10/a, 60020 Ancona, Italy

Sustainable Mobility and Accessibility for people with disabilities: Emerging Trends, Policy Challenges and Evolution in motor insurance

simona viciani, sara landini, emilia giusti, giulia biagioni

università di firenze, Italy

Environmental pollutants and human DNA methylation variability: The Bussi sul Tirino SNI

Giorgia Bolognesi¹, Vincenzo Iannuzzi¹, Stefania Sarno¹, Augusto De Sanctis², Maria Giulia Bacalini³, Francesco Ravaioli⁴, Francesca Ferraresi⁵, Claudia Sala⁶, Sara De Fanti⁴, Donata Luiselli⁷, Elena Marasco⁸, Paolo Garagnani⁶, Davide Gentilini^9,10, Luciano Calzari¹⁰, Alessandro Gargini¹, Maria Filippini¹, Cristina Giuliani¹

1: Department of Biological, Geological and Environmental Sciences, University of Bologna, 40126 Bologna, Italy.; 2: S.O.A. - Forum H2O, 65127 Pescara, Italy; 3: Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy; 4: IRCCS Institute of Neurological Sciences, 40139 Bologna, Italy; 5: Department of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy; 6: Department of Medical and Surgical Sciences, University of Bologna, 40126 Bologna, Italy; 7: Department of Cultural Heritage (DBC), Ravenna Campus, University of Bologna, 48121 Ravenna, Italy; 8: Personal Genomics Ltd, 37136 Verona, Italy; 9: Department of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy; 10: Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, 20095 Cusano Milanino, Milan, Italy

Income inequalities in mortality in the elderly population in Italy: differences between household and individual income.

Lucia Coppola, Luisa Frova, Enrico Grande, Marilena Pappagallo, Isabella Siciliani

ISTAT, Italy

Investigating Disparities in Cause-Specific Mortality based on Education in Italy

Alessandro Feraldi¹, Marilena Pappagallo², Cristina Giudici¹, Luisa Frova²

1: MEMOTEF Department, Sapienza University of Rome; 2: Italian National Institute of Statistics (ISTAT)

Is culture good for health? A pseudo-panel approach

Elena Pirani¹, Marta Pittavino², Sabrina Iommi³, Maria Luisa Maitino³

1: University of Florence (UNIFI); 2: Ca' Foscari University of Venice (UNIVE); 3: Istituto Regionale Programmazione Economica Toscana (IRPET)

Mapping School Supply: How Local Educational Density Shapes Family and Youth Decisions

Iacopo Moreschini, Isabella Sulis, Mariano Porcu, Cristian Usala

University of Cagliari, Italy

The Socioeconomic Status Gradient in Pain: A Cross-Country Analysis

Enrica Croda

Ca' Foscari University of Venice, Italy

Education, Learning, and Training for Active Ageing: A Study of National Good Practices

Vanna Boffo¹, Michele Bertani², Donatella Bramanti³, Rabih Chattat⁴, Laura Formenti⁵

1: University of Florence, Italy; 2: Cà Foscari University of Venice, Italy; 3: Università Cattolica del Sacro Cuore of Milan, Italy; 4: University of Bologna; 5: University of Milano Bicocca

A Dynamic Active Ageing Index: Evidence from the SHARE data

Koray Aktas, Agar Brugiavini, Matteo Cazzaro, Ya Gao

Ca' Foscari University of Venice, Italy

Transitions from labour market to the retirement world. Education, Lifelong Learning and Active Ageing

Debora Daddi, Vanna Boffo

University of Florence, Italy

Ageing at Work in the Healthcare Sector. Active Ageing and Social Quality among Senior Workers in Lombardy and Campania

GIUSTINA ORIENTALE CAPUTO¹, MARINO PEZZOLO², ADRIANA CERASUOLO³

1: Università degli Studi di Napoli Federico II, Italy; 2: Università degli Studi di Napoli Federico II, Italy; 3: Università degli Studi di Napoli Federico II, Italy

Skill obsolescence and lifelong learning in the ageing workforce: the effect on job satisfaction

Corrado Polli¹, Valentina Ferri², Eleonora Trappolini³, Rita Porcelli⁴, Alessandra De Rose³

1: Inapp, Italy; 2: Inapp, Italy; 3: Sapienza Università di Roma, Italy; 4: Inapp, Italy

Self-guided home-based rehabilitation for upper limb motor recovery in people with stroke

Alfonc Baba^1,2, Diego Bulcao-Visco³, Margherita Bertuccelli⁴, Anna Tiso⁵, Caterina Pozzan⁵, Chiara Verbano⁵, Alessandra Del Felice^1,2

1: Dipartimento di Neuroscienze, Università degli Studi di Padova, Italy; 2: Padova Neuroscience Center, Università degli Studi di Padova, Padova, Italy; 3: Programa de Pós-graduação em Ciências da Saúde & Laboratório de Neurofuncional, Departamento de Ciências Biológicas e Saúde, Universidade Federal do Amapá, Macapá, Brasil; 4: Dipartimento di Ingegneria dell’Informazione, Università degli Studi di Padova, Padova, Italy; 5: Dipartimento di Tecnica e Gestione dei Sistemi Industriali, Università degli Studi di Padova, Padova, Italy

ICare.IT – AvereCura - A longitudinal study on care burden of informal caregivers of people with dementia: preliminary analysis of objective and subjective variables

Angela Berardi, Ylenia Druda, Paola Di Florio, Marcello Sicbaldi, Francesco Palmese, Francesca Zanasi, Eva Bei, Ilaria Chirico, Sara Trolese, Emma Capulli, Francesca Ingravallo, Marco Albertini, Marco Domenicali, Alessandro Silvani

Alma Mater Studiorum - Università di Bologna, Italy

The Social Side of Frailty: Measurement and implications for Physical Health in Older Europeans

Annalisa Donno¹, Elisa Cisotto², Giovanna Boccuzzo¹

1: University of Padua, Italy; 2: Catholic University, Italy

Animal Assisted Interventions in Older Residents of Assisted Living Facilities: a preliminary experience in Florence

Ilaria Ambrosino, Olimpia Martini, Fiorella Aversano, Ilenia Barbieri, Greta Ceccarelli, Arianna Tariello, Ludovica Ceolin, Giulia Spanalatte, Thierry Wenger, Giulia Rivasi, Enrico Mossello, Andrea Ungar

University of Florence and Division of Geriatric and high-intensity Care Medicine and Geriatric Cardiology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy

Estimating disability prevalence and incidence in Italy using a multistate model: merging information from different sources

Enrico Roma¹, Rossella Miglio²

1: University of Bologna, Department of Statistical Science ”Paolo Fortunati”, Italy,; 2: University of Bologna, Department of Statistical Science ”Paolo Fortunati”, Italy,

Aging in place with disability: data from the city of Bergamo

Antonella Gilardoni¹, Stefania Butti¹, Mabel Giraldo¹, Francesca Morganti^1,2

1: Department of Human and Social Sciences, University of Bergamo, Italy; 2: CHL - Center for Healthy Longevity, University of Bergamo, Italy

Aging in Place and housing selection: a qualitative analysis of the key determinants that shape later life living models

Stefania Butti^1,3, Emanuele Garda^2,3, Maria Gattuso¹, Inaihá Laureano Benincá¹, Francesca Morganti^1,3

1: Department of Human and Social Sciences, University of Bergamo; 2: Department of Engineering and Applied Sciences, University of Bergamo; 3: CHL – Center for Healthy Longevity, University of Bergamo

Private autonomy meets social solidarity (?) the legal dilemma of senior cohousing

Paola Francesca Rizzi

Università degli Studi di Bari Aldo Moro, Italy

CASA PROJECT: AGING IN BERGAMO. HOW NEIGHBORHOODS AND URBAN SPACES CAN SHAPE OPPORTUNITIES FOR HEALTHY LONGEVITY IN MID-SIZED CITIES

Francesca Morganti¹, Emanuele Garda¹, Michela Cameletti², Stefania Butti¹, Marta Rodeschini², Gregorio Pezzoli², Oksana Bardhi², Giorgia Brillanti¹

1: CHL Centre for Healthy Longevity, University of Bergamo - Italy; 2: University of Bergamo - Italy

A key advantage of implementing a SUMP: providing the elderly with access to transportation infrastructure

Elisabetta Venezia

University of Bari Aldo Moro, Italy

Beyond Kinship: Intergenerational Relationships and Support for Young Non-Family members. Evidence from Italian Baby Boomers

Andrea Antonini, Alessandro Rosina, Francesca Luppi, Emiliano Sironi

Università Cattolica del Sacro Cuore, Milano, Italy

Experimentation of an Intergenerational Subsidiarity project between the elderly, young workers and families

Massimo Cantelmi

La Compagnia degli Ultimi all'Esquilino di "Chiesa in uscita", Italy

Who carries out the intention to leave the parental home? An analysis based on the integration of survey and register data

Lucia Coppola, Romina Fraboni, Isabella Siciliani, Daniele Spizzichino

Istat, Italy

Characteristics, working and living conditions of migrant female domestic and care workers in France, Germany, Italy, and Spain

Giuseppe Gabrielli¹, Anna Paterno², Salvatore Strozza¹, Rocco Mazza²

1: University of Naples Federico II, Italy; 2: University of Bari "A. Moro", Italy

From aspirations to enrolment: educational pathways of migrant-origin students in Italy

Alessio Buonomo¹, Cinzia Conti², Giuseppe Gabrielli¹, Fabio Massimo Rottino², Salvatore Strozza¹

1: Federico II, Italy; 2: Istat

How time allocation shapes life satisfaction in old age: A compositional approach

Martina Salierno, Annalisa Donno, Maria Letizia Tanturri

University of Padua, Italy

How Time Is Spent Matters: Activities, Solitude, and Loneliness Among Older Adults

Maria Letizia Tanturri, Annalisa Donno, Martina Salierno

University of Padua, Italy

Enhancing Physical Activity Motivation in Older Adults: An Augmented Reality-Based Intervention Grounded in Self-Determination Theory

Andrea Chirico¹, James Dawe¹, Tommaso Palombi¹, Barbara Cazzolli¹, Michele Zacchilli¹, Guido Alessandri¹, Lorenzo Filosa¹, Anna M. Borghi¹, Chiara Fini¹, Chiara Antoniucci¹, Jessica Pistella¹, Roberto Codella², Fabio Alivernini¹, Roberto Baiocco¹, Maurizio Mancini¹, Fabio Lucidi¹

1: "Sapienza" Università di Roma, Italy; 2: University Milano La Statale, Milano, Italy

Psychometric Properties of the Subjective Vitality and Depletion Scale: A Cross-Cultural Study among Older Adults

James Dawe², Andrea Chirico¹, Tommaso Palombi¹, Barbara Cazzolli¹, Michele Zacchilli¹, Guido Alessandri¹, Lorenzo Filosa¹, Anna M. Borghi¹, Chiara Fini¹, Chiara Antoniucci¹, Jessica Pistella¹, Roberto Baiocco¹, Fabio Alivernini¹, Fabio Lucidi¹

1: Department of Developmental and Social Psychology, Sapienza University of Rome, Rome, Italy; 2: Department of Humanities and Social Sciences, Universitas Mercatorum Telematic University, Rome, Italy

Animal Assisted Interventions in older adults attending Day Care Centres: a pilot study

Arianna Tariello¹, Ilenia Barbieri¹, Ilaria Ambrosino¹, Fiorella Aversano¹, Greta Ceccarelli¹, Olimpia Martini¹, Ludovica Ceolin¹, Giulia Spanalatte¹, Thierry Wenger¹, Giulia Rivasi^1,2, Enrico Mossello^1,2, Andrea Ungar^1,2

1: University of Florence and Division of Geriatric and high-intensity Care Medicine and Geriatric Cardiology; 2: Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

Where would you rather live? Blue and Green Zones of Longevity in Italy

Elisabetta Barbi, Giacomo Lanfiuti Baldi

Sapienza University of Rome, Italy

The role of Aging and Cognitive Reserve in Motor Imagery Ability: Behavioral Insights into Strategy Use

Bianca Monachesi¹, Stefania Lucia¹, Elisabetta Pisanu¹, Silvia Fornaro¹, Raffaella I. Rumiati^1,2

1: SISSA, Italy; 2: University of Tor Vergata, Italy

Evaluating frailty among older adults using a principal components-based indicator

Pietro Belloni

University of Padova, Italy

Change and Resistance in Digital Self-Care: Motivational Processes in Older Adults with Chronic Conditions

Daniela Lemmo¹, Fabrizio Mezza¹, Alessandra Cuomo², Antonio Bianco³, Antonella Di Donato², Vincenzo De Luca³, Maddalena Illario³, Guido Iaccarino², Maria Francesca Freda¹

1: Department of Humanities, University of Naples Federico II, Naples, Italy; 2: Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy; 3: Department of Public Health, University of Naples Federico II, Naples, Italy

Administrative data for reproducible frailty assessment

Maurizio Nicolaio, Margherita Silan, Giovanna Boccuzzo

University of Padova, Italy

"Unveiling the Hidden Burden of Frailty in Burning Mouth Syndrome: A Multidimensional Case-Control Study on Physical, Cognitive, and Psychosocial Decline"

Daniela Adamo¹, Federica Canfora², Cristina D'Antonio³, Vincenzo De Luca², Jacopo Meglio², Gennaro Musella⁴, Giulia Ottaviani⁵, Maddalena Illario²

1: Link Campus University, Federico II University of Naples, Italy; 2: Federico II University of Naples, Italy; 3: Magna Grecia, Catanzaro, Italy; 4: University of Foggia; Italy; 5: University of Trieste, Italy

The impact of attentional mechanisms on reading ability in healthy aging

Sara Pegoraro^1,2,3, Simone Galati¹, Alessio Facchin⁴, Camilla Frontoni¹, Elena Rolandi⁵, Emanuela Bricolo¹, Lisa Saskia Arduino⁶, Roberta Daini^1,2,7

1: University of Milano-Bicocca, Italy; 2: Milan Centre for Neuroscience (NeuroMI), Milano, Italy; 3: Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden; 4: Research Center in Neuroscience, Magna Graecia University, Catanzaro Italy; 5: Golgi Cenci Foundation, Abbiategrasso (Milan), Italy; 6: Department of Human Sciences - LUMSA University, Rome, Italy; 7: IRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy

Integrating Spatial Analysis and Agent-Based Modeling to Assess Long-Term Care Sustainability in Italy Inner Areas

Stefania Bandini, Roberto Garrone, Paola Salvatore

University of Milano-Bicocca, Italy

Redefining Marginality: Disentangling service accessibility in Italy’s Inner Areas and the role of NRRP

Nicola Caravaggio, Giuliano Resce, Giorgio Ialenti

Università degli Studi del Molise, Italy

Assessing Walkability in Italian Inner Areas: the Case of Premeno and Public Services Reallocation

Luca Borrè, Alessio De Pellegrin, Stefania Bandini

University of Milano-Bicocca, Italy

Distance and Needs: an index to capture the demographic curvature in care demand of dependent older people

Carlo Lallo¹, Emilio Cameli¹, Federico Benassi²

1: University of Molise, Italy; 2: University of Naples Federico II, Italy

Invisible hands, tangible ties: digital and relational practices of older informal caregivers in an Italian inner area

Federica Cretazzo

University of Milano-Bicocca, Italy

Spatial differences in Italy’s population ageing: insights from a diachronic multi-scale approach (1991-2021)

Massimo Armenise¹, Federico Benassi², Marianna Mantuano¹

1: ISTAT, Italy; 2: Università Federico II, Napoli

Ageing at the extremes: internal mountainous areas in Northern Italy

Tiziana Nazio, Francesca Donati

University of Eastern Piedmont, Italy

Systemic Depopulation's Geography: Italian and Austrian Municipalities' Diverging Paths (2001-2023)

Emilio Cameli¹, Carlo Lallo¹, Federico Benassi², Cecilia Tomassini¹

1: University of Molise; 2: University of Naples Federico II

The contribution of telomere biology to aging

Fabrizio d'Adda di Fagagna

CNR

A novel control of mitochondrial structure and function by the autophagic receptor SQSTM1/p62 in aging pathophysiology

Enrico Milan^1,2, Maria Materozzi^1,3, Francesca Paradiso¹, Massimo Resnati¹, Elena Ruggieri¹, Ugo Orfanelli¹, Andrea Raimondi⁴, Fabiana Longo⁵, Paola Podini⁶, Luca Drusian⁷, Laura Cassina⁷, Daniela Merlotti³, Angelo Quattrini⁶, Alessandra Boletta⁷, Francesca Maltecca^2,5, Luigi Gennari³, Simone Cenci^1,2

1: San Raffaele Scientific Institute, Division of Genetics and Cell Biology, Age Related Diseases Unit; 2: Università Vita-Salute San Raffaele; 3: University of Siena, Department of Medicine, Surgery and Neurosciences; 4: San Raffaele Scientific Institute, Experimental Imaging Center; 5: San Raffaele Scientific Institute, Division of Neuroscience, Neurogenomics; 6: San Raffaele Scientific Institute, Division of Neuroscience - INSPE - Institute of Experimental Neurology, Experimental Neuropathology; 7: San Raffaele Scientific Institute, Division of Genetics and Cell Biology, Molecular Basis of Polycystic Kidney Disease

Unraveling the role of the multifaceted protein HMGB1 in maintaining tissue homeostasis upon aging: spotlight on fat and skeletal muscle

Erika Di Domenico¹, Elena Ruggieri², Federica Cirillo³, Ivana Lavota³, Matteo Panebianco², Paola Rota³, Emilie Venereau²

1: Università Vita Salute San Raffaele, Italy; 2: Tissue Regeneration and Homeostasis Unit, Division of Genetics and Cell Biology, IRCCS Ospedale San Raffaele, Milan; 3: Department of Bioscences, University of Milan, Milan

Identification and characterization of a novel gene that controls ageing

Marco Sandri

University of Padova, Italy

Aging tunes social preference and the response to social deprivation in zebrafish

Giada Cellot, Safaa Mamoun Abdelmageid Ali, Anabela Palandri, Audrey Franceschi Biagioni, Giacomo Amerio, Anna Burato, Giuseppe Legname, Davide Zoccolan, Laura Ballerini

International school for advanced studies (SISSA), Italy

Efficacy of a placebo administered with and without deception on psychological, cognitive, and physical functioning in healthy older adults

Diletta Barbiani, Francesco Pagnini

Università Cattolica del Sacro Cuore, Italy

Views of cognitive aging: a new tool and its associations with cognitive and psychological functioning in midlife and older age

Enrico Sella, Erika Borella

Department of General Psychology, University of Padova, Italy

Regulatory Emotional Self-Efficacy in Managing Negative Emotions at Work: A Validation Study

Simone Tavolucci, Lorenzo Filosa, Valentina Sommovigo, Valentina Rosa, Roberto Baiocco, Anna Borghi, Fabio Alivernini, Andrea Chirico, Chiara Fini, Jessica Pistella, Tommaso Palombi, James Dawe, Chiara Antoniucci, Ilenia Falcinelli, Fabio Lucidi, Guido Alessandri

Sapienza, Università di Roma, Italy

Linking sociality to extended lifespan and aging: an insight from bioanthropology

Vincenzo Iannuzzi¹, Nicolas Narboux-Nême², Andrea Lehoczki^3,4, Giovanni Levi², Cristina Giuliani¹

1: Laboratory of Molecular Anthropology & Centre for Genome Biology, Department of Biological, Geological and Environmental Sciences, University of Bologna, Italy; 2: Physiologie Moléculaire et Adaptation, CNRS UMR7221, Département AVIV, Muséum National d'Histoire Naturelle, Paris, France; 3: Doctoral College, Health Sciences Program, Semmelweis University, Budapest, Hungary; 4: Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary

Micro-transitions: interpreting identity, learning, agency, and care in later life

Laura Formenti¹, Davide Cino¹, Maria Vittoria Bufali², Amelia Compagni², Francesca Romana Loberto¹

1: University of Milano-Bicocca, Italy; 2: Bocconi University

Rethinking Ageing: Quality of Life, Regional Inequalities and Social Innovation in the Age-It Study

Paolo Contini

University of Bari Aldo Moro, Italy

Geography, Parental Education, and University Accessibility in Italy: Insights from Veneto and Sicily

Marina Chiaramonte¹, Andrea Priulla², Massimo Attanasio³

1: Università degli Studi di Palermo; Fulbright Research Scholar (US-Italy); 2: Department of Economics and Law, University of Enna KORE, Enna, Italy; 3: Department of Business, Economics, and Statistics – University of Palermo, Palermo, Italy

Predicting reperfusion injury and functional status after stroke using blood biomarkers

Leonardo Tenori¹, Alessia Vignoli¹, Elena Sticchi¹, Benedetta Piccardi¹, Vanessa Palumbo², Cristina Sarti¹, Alessandro Sodero¹, Francesco Arba¹, Enrico Fainardi¹, Anna Maria Gori¹, Betti Giusti¹, Ada Kura¹, Marzia Baldereschi³

1: University of Florence, Italy; 2: Stroke Unit, Careggi University Hospital; 3: Italian National Research Council (CNR)

Sensor Technologies for Movement Analysis in Active Ageing: Toward Remote Capacity and Function Assessment in the Ageing Population

Dario Ghezzi, Filippo Palumbo, Paolo Barsocchi

National Research Council of Italy (ISTI-CNR), Italy

Uncovering the needs of older adults in remote areas of Italy

Maria Vittoria Bufali¹, Formenti Laura², Cino Davide², Loberto Francesca Romana², Amelia Compagni¹

1: Bocconi University, Italy; 2: University of Milano-Bicocca, Italy

TERRA as a Senescence and Prognostic Biomarker in Peripheral Blood Mononuclear Cells: Findings from Colorectal Cancer Patients and In Vitro Studies

Jacopo Lidonnici¹, Marzia Morello², Maria Raffaella Petrara², Elena Ruffoni², Francesca Bergamo³, Sara Lonardi³, Stefano Indraccolo⁴, Anita De Rossi¹, Silvia Giunco^1,2

1: Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; 2: Immunology and Diagnostic Molecular Oncology Unit, Veneto Institute of Oncology IOV– IRCCS, Padova, Italy; 3: Department of Oncology, Veneto Institute of Oncology IOV – IRCCS, Padova, Italy; 4: Basic and Translational Oncology Unit, Veneto Institute of Oncology IOV– IRCCS, Padova, Italy

Uncovering Disease Progression Subtypes in Aging Populations through Explainable Multivariate Longitudinal Clustering: Applications to Alzheimer’s Disease and Sepsis

Patrizia Ribino¹, Maria Mannone¹, Claudia Di Napoli¹, Giovanni Paragliola¹, Davide Chicco², Francesca Gasparini²

1: Consiglio Nazionale delle Ricerche, Istituto di Calcolo e Reti ad Alte Prestazioni (ICAR); 2: Università degli Studi di Milano-Bicocca - Dipartimento di Informatica, Sistemistica e Comunicazione

Enhancing patient experience through waiting room environment in healthcare settings: Investigating user perspective.

Lorena Rossi¹, Eleonora Bonifazi¹, Rachele Alessandra Marziali¹, Valentina Tombolesi¹, Nicoletta Setola², Elena Bellini², Vera Stara¹

1: IRCCS INRCA, Ancona - Scientific Direction; 2: University of Florence - Department of Architecture DIDA TESIS

NEUTROPHIL TO LYMPHOCYTE RATIO AS A PREDICTIVE BIOMARKER FOR DEMENTIA: FINDINGS FROM A PROSPECTIVE COHORT STUDY IN INDIVIDUALS WITH MILD COGNITVE IMPAIRMENT

Antonella Gallo¹, Massimo Montalto^1,2, Maria Camilla Cipriani¹, Riccardo Calvani^1,2, Antonio Cherubini³, Eleonora Ianuà², Tommaso Giani¹, Anna Picca^1,4, Rossella Giordano¹, Eleonora Clemente¹, Rosa Liperoti^1,2

1: Department of Geriatric, Orthopedic and Rheumatologic Sciences, Fondazione Policlinico Universitario. A. Gemelli, IRCCS, Rome, IT; 2: Department of Geriatric and Orthopedic Sciences, Università Cattolica del Sacro Cuore, Rome IT; 3: Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, IT; Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, IT; 4: Department of Medicine and Surgery, LUM University, Casamassima, IT

Patterns of verbal learning in cognitive decline: a preliminary study

Gianluca Scotto di Tella, Rita Pezzella, Vittoria Canzanella, Maddalena Vasto, Angelo Ioanna, Mario Rosario Spoleto, Sara Rinaldi Landolina, Filomena Forino, Stefano Maisto, Fabrizia Gatta, Giuseppe Rengo, Grazia Daniela Femminella

Department of Translational Medical Sciences University of Naples Federico II, Italy

Working "as long as I can". Domestic workers over 60 in Italy

Antonio Sanguinetti

Cnr, Italy

Assessment of cognitive performances in Cystic Fibrosis adult patients

Jolanda Somma¹, Paola Iacotucci², Grazia Daniela Femminella¹, Lorenza Ferrillo¹, Serena Buonaurio¹, Giuseppe Rengo^1,3, Vincenzo Carnovale¹

1: Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, Italy; 2: Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Naples, Italy; 3: Istituti Clinici Scientifici Maugeri IRCCS, Scientific Institute of Telese Terme, Telese Terme, BN, Italy

Emotional Verbal Fluency Across the Lifespan: The Role of Emotion Suppression and Cognitive Reserve

Elisabetta Pisanu¹, Bianca Monachesi¹, Stefania Lucia¹, Silvia Fornaro¹, Raffaella I. Rumiati^1,2

1: International School for Advanced Studies (SISSA), Trieste, Italy; 2: University of Tor Vergata, Rome, Italy

Exploring the Dynamics of Motivation in Physical Activity among Older Adults Through Panel Network Approach

Tommaso Palombi, Andrea Chirico, Fabio Lucidi, Chiara Antoniucci, Jessica Pistella, Roberto Baiocco, Guido Alessandri, Lorenzo Filosa, Simone Tavolucci, Chiara Fini, Anna Borghi, James Dawe, Elisa Cavicchiolo, Fabio Alivernini

Sapienza, Italy

Animal Assisted Interventions to improve well-being of older persons: a case report

Olimpia Martini, Ilaria Ambrosino, Fiorella Aversano, Ilenia Barbieri, Greta Ceccarelli, Arianna Tariello, Ludovica Ceolin, Giulia Spanalatte, Thierry Wenger, Giulia Rivasi, Enrico Mossello, Andrea Ungar

University of Florence and Division of Geriatric and high-intensity Care Medicine and Geriatric Cardiology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

Linking systemic biomarkers, brain morphometry, and brain function in PD: a focus on attention deficits

Simone Cauzzo¹, Eleonora Fiorenzato^1,2, Francesca Vianello¹, Roberta Biundo³, Renzo Manara⁴, Alessandra Bertoldo², Angelo Antonini^1,2

1: Parkinson Disease and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE), Department of Neuroscience, University of Padova, Padova, Italy; 2: Padova Neuroscience Center (PNC), Department of Neuroscience, University of Padova, Padova, Italy; 3: Department of General Psychology, University of Padova, Padova, Italy; 4: Neuroradiology Unit, Padova University Hospital, Padova, Italy

Cognitive Efficiency in Aging: The Jointly Role of Cognitive Reserve and Emotional Intelligence

Stefania Lucia¹, Elisabetta Pisanu¹, Silvia Fornaro¹, Bianca Moncachesi¹, Raffaella Rumiati^1,2

1: 1Neuroscience Area, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy; 2: 2Department of System Medicine, University of Tor Vergata, 00133 Rome, Italy.

Proteomic Analysis of Red Blood Cell Membrane Proteins as Biomarkers of Aging: A Label- Free Quantitative Approach

Vincenzo Lettera¹, Giuseppina Cacciatore¹, Anna Illiano², Gabriella Pinto², Marco Malavolta³, Angela Amoresano², Giuseppe Passarino¹, Anna Maria Carmela Napoli¹, Donatella Aiello¹

1: Università della Calabria, Italy; 2: Università degli Studi di Napoli Federico II; 3: INRCA

A PRISMA-Based Systematic Review of the Gendered Impacts of the Fornero Pension Reform: Female Precarity in Italy

Emre Kurt

Università degli Studi dell'Insubria, Italy

Mobile Remote Photoplethysmographic system for vital signs estimation and its perceived usability evaluation by elderly people

Andrea Manni, Anna Maria Carluccio, Andrea Caroppo, Pietro Aleardo Siciliano, Alessandro Leone

National Research Council of Italy, Italy

Knightian job insecurity: Theory and time-series evidence from the Share survey in selected European countries

Luca Vota

Institute for Studies on the Mediterranean of the National Research Council of Italy (CNR-ISMed), Italy

Development of an innovative in-situ platform for real-time Airborne Pathogen Detection via RNA Amplification on Solid Supports

Laura Blasi², Alessandra Calogiuri¹, Elisa Sciurti³, Daniele Bellisario⁴, Vanessa Esposito⁷, Pietro Aleardo Siciliano⁹, Luca Nunzio Francioso¹⁰, HAFIZ USMAN TAHSEEN⁸, Francesco Ruighi⁵, Flavio Casino⁶

1: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 2: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 3: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 4: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 5: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 6: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 7: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 8: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 9: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus; 10: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus

ACTIVATION OF CARDIAC MYOSIN FILAMENT DURING SYSTOLE WITH DIFFERENT AFTERLOADS

Ilaria Morotti¹, Marco Caremani¹, Giulia Sautariello¹, Mariano Balzano¹, Matteo Marcello², Irene Pertici¹, Pasquale Bianco¹, Theyencheri Narayanan³, Gabriella Piazzesi¹, Vincenzo Lombardi¹, Massimo Reconditi¹, Marco Linari¹

1: University of Florence, Italy; 2: Généthon, Évry-Courcouronnes, France; 3: ESRF, Grenoble, France

Multi-omics profiling unveils senescence programs induced by CDK4/6 inhibitors in endothelial cells

Marianna Talia, Francesca Silvestri, Chiara Meliti, Marcello Maggiolini, Rosamaria Lappano

University of Calabria

Immunomodulation as a tool to fight cancer cachexia and sarcopenia in the elderly

Chiara Noviello^1,2, Noemi Iaia^1,2, Benedetta Genta², Giacomo Rubini², Fabio Penna², Paola Costelli²

1: University of Eastern Piedmont, Italy; 2: University of Turin

HUMAN VOLATILOME ANALYSIS BY SPME-GC/MS AND A IMPEDIMETRIC SPECTROSENSOR

Giulia My¹, Angiola Forleo¹, Marika Massaro², Stefano Quarta², Giuseppe Santarpino³, Alessandro Fiorentino³, Stefano D'Amico⁴, Antonio Vincenzo Radogna^5,1, Simonetta Capone¹

1: National Research Council, Institute for Microelectronics and Microsystems (CNR-IMM), 73100 Lecce, Italy; 2: National Research Council, Institute of Clinical Physiology (CNR-IFC), 73100 Lecce, Italy; 3: University "Magna Graecia", 88100 Catanzaro, Italy; 4: Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy; 5: Department of Experimental Medicine, University of Salento, 73100 Lecce, Italy

Does Easier Family Reunification Improve Immigrants' Well-being? Age Heterogeneity in Psychological Outcomes

Tiziana Venittelli, Maria Rosaria Carillo, Massimiliano Cerciello

Parthenope University of Naples, Italy

Serum Ferritin Levels as Predictors of Frailty Severity in Older Adults

Laura de Lisio¹, Laura Andreea Ceparano¹, Chiara Di Lorenzo¹, Claudia Canitano¹, Anna De Simone¹, Antonio Di Maio¹, Raffaele Formisano¹, Fabrizia Gatta¹, Alessandro Orrera¹, Giovanni Saccon¹, Laura Petraglia¹, Grazia Daniela Femminella¹, Graziamaria Corbi¹, Nicola Ferrara¹, Leonardo Bencivenga¹, Dino Franco Vitale², Giuseppe Rengo¹

1: Dipartimento di Scienze Mediche Traslazionali, Università di Napoli Federico II, Italy; 2: Clinica San Michele, Maddaloni, CE, Italy.

Selenoprotein T as a Novel Guardian Against Cardiomyocyte Senescence: Insights into its Interaction with the CD36 Receptor

Anna De Bartolo¹, Vittoria Rago², Naomi Romeo¹, Marika De Cicco¹, Benjamin Lefranc^3,4, Jérôme Leprince^3,4, Giuseppe Passarino⁵, Pasquale Pagliaro^6,7, Youssef Anouar³, Carmine Rocca^1,7, Tommaso Angelone^1,7

1: Cellular and Molecular Cardiovascular Physiology and Pathophysiology Laboratory, Department of Biology, Ecology and Earth Sciences (DiBEST), University of Calabria, Rende, CS, Italy; 2: Human Anatomy Laboratory, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, CS, Italy; 3: UNIROUEN, Inserm U1239, Neuroendocrine, Endocrine and Germinal Differentiation and Communication (NorDiC), Rouen Normandie University, Mont-Saint-Aignan, France; 4: UNIROUEN, UMS-UAR HERACLES, PRIMACEN, Cell Imaging Platform of Normandy, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France; 5: Genetics Laboratory, Department of Biology, Ecology and Earth Sciences (DiBEST), University of Calabria, Rende, CS, Italy; 6: Department of Clinical and Biological Sciences, University of Torino, Turin, Italy; 7: National Institute of Cardiovascular Research (INRC), Bologna, Italy.

Impact of Built Environment on Health: Towards a Domain Ontology

Anđela Đinđić, Daniele Spoladore, Marco Sacco

CNR, Italy

Care-Ready Homes: Design Guidelines for Adapting Spaces With Assistive Technologies

Federica Romagnoli, Teresa Villani, Tiziana Ferrante

Department of Planning, Design, Architectural Technology - Sapienza University of Rome, Italy

Collaborative Housing Models for Older Adults in Spain: An Alternative to Traditional Aging

Noelia Teijeiro Cal¹, Stefania Butti², Francesca Morganti², Raquel Martínez Buján¹

1: Societies in Movement Research Team, Universidad de A coruña, Spain; 2: Centre for Healthy Longevity, University of Bergamo

The role of Mitochondrial DNA Copy-Number and Telomere Length in age-related neurodegenerative diseases: outcomes from a southern Italian cohort of Alzheimer’s disease patients.

Annamaria Cerantonio¹, Alberto Montesanto², Luigi Citrigno¹, Patrizia Spadafora¹, Antonio Qualtieri¹, Selene De Benedittis¹, Beatrice Maria Greco^1,2, Ersilia Paparazzo², Raffaele Maletta³, Giuseppe Passarino², Francesca Cavalcanti¹

1: Institute for Biomedical Research and Innovation (IRIB) – National Research Council; 2: Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende 87036, Italy; 3: Regional Neurogenetic Centre (CRN), Department of Primary Care, Azienda Sanitaria Provinciale di Catanzaro

Clinical Trial Placebo-Controlled via accelerated TMS over the Dorsolateral Prefrontal Cortex in Alzheimer’s Disease: EEG Markers of Executive Control and Social Cognition

Marianna Delussi¹, Emmanuella Ladisa¹, Alessandro Introna¹, Chiara Abbatantuono¹, Giulia Paparella², Giusy Tancredi¹, Elena Ammendola¹, Elvira Brattico^1,3, Marina de Tommaso¹

1: University of Bari Aldo Moro, Italy; 2: IRCCS Neuromed, Pozzilli (IS), Italy; 3: Department of Clinical Medicine Aarhus University, Danimarca

Effects of Irisin on Osteoarthritis in a SAMP8 Murine Model: ELIS-IR Preclinical Stud

Giuseppina Di Giacomo^1,2, Veronica Tilotta², Roberta Bernardini³, Ludovica Pangrazzi², Luca Ambrosio^1,2, Fabrizio Russo^1,2, Rocco Papalia^1,2, Vincenzo Denaro², Gianluca Vadalà^1,2

1: Laboratory for Regenerative Orthopaedics, Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy; 2: Operative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio- Medico, Rome, Italy; 3: Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome,Italy

Age discrimination in the literature: a Systematic Literature Review and Bibliometric Analysis

Raffaele Silvestre, Alessandro Sapio, Rita Lamboglia

University of Naples Parthenope, Italy

F.L.O.WeR. (For Life Organ We Research): A Next-Generation of Biodynamic Machine Perfusion (BMP) for organ preservation to promote healthy longevity

Mattia Dimitri¹, Filippo Bigi¹, Pietro Matucci Cerinic², Fabio Staderini³, Margherita Romiti¹, Stefano Bacci⁴, Martina Ricci¹, Fabio Cianchi³, Federico Carpi¹, Andrea Corvi¹

1: Dipartimento di Ingegneria Industriale | Università degli Studi di Firenze; 2: Clinica Chirurgica, Dipartimento di Chirurgia, Ospedale Universitario S. Maria della Misericordia, Udine; 3: Dipartimento di Medicina Sperimentale e Clinica | Università degli Studi di Firenze; 4: Dipartimento di Biologia | Università degli Studi di Firenze

Digital Governance for Ageing Societies: a Data Platform for Territorial Vulnerabilty Assessment and Mapping

Luca Bonofiglio¹, Natascia Fanecco², Antonella Montagner³, Giovanni Quattrocchi⁴, Davide Valduga⁵, Rosa Anna Laboccetta⁶

1: Municipia SpA, Italy; 2: Municipia SpA, Italy; 3: Municipia SpA, Italy; 4: Municipia SpA, Italy; 5: Municipia SpA, Italy; 6: Municipia SpA, Italy

PHYSICAL EXERCISE IN HEMODIALYSIS PATIENTS WITH END-STAGE KIDNEY DISEASE (PEHEDAL-ESKD): A NEW THERAPEUTIC APPROACH

E. Satta, C. Romano, M.C. Sibilio, G. Erbaggio, E. Salomone, S. Vaia, G. Iadicicco, M. Serrapica, P. Ferrante, R. De Luca, R. Di Martino

Nefrocenter Research and Nefrocenter Scarl, Torre del Greco, Naples, Italy, Italy

Polydopamine Nanoparticles Protect Endothelium from Ischemia-Reperfusion Injury via Antioxidant and Anti-Inflammatory Mechanisms

Serena Babboni¹, Giuseppina Basta¹, Lara Russo¹, Silverio Sbrana¹, Matteo Battaglini², Alessio Carmignani², Gianni Ciofani², Serena Del Turco¹

1: Institute of Clinical Physiology, CNR, Pisa; 2: Center for Materials Interfaces, IIT, Pontedera

Opening remarks

Matteo Lorito¹, Alessandra Petrucci², Cristina Freguja³, Anna Maria Colao⁴

1: Rettore dell'Università di Napoli Federico II; 2: Rettrice dell'Università di Firenze; 3: Istituto Nazionale di Statistica (ISTAT); 4: Consiglio Superiore di Sanità

Keynote Speaker

Wolfgang Lutz

International Institute for Applied Systems Analysis – IIASA, Vienna, Austria

Keynote Speaker (remote)

Alina Lupu

Commissione Europea

How raising the Full Retirement Age affects early retirement choices: insights from the interaction of two policies

Elena Bassoli¹, Ylenia Brilli²

1: ETH, Switzerland; 2: Ca' Foscari University of Venice

Paths to Retirement

Giuseppe Pio Dachille¹, Monica Pia Cecilia Paiella^1,2, Gianfranco Santoro¹

1: INPS, Italy; 2: University of Naples "Parthenope"

Retirement reloaded: Bridge Employment, Ageing Workforce and the Digital Transition

Luisa Errichiello, Daniele Demarco, Orsola Salmista

National Research Council of Italy ( CNR), Institute for Studies on the Mediterranean (ISMed)

The Pedagogical Value of Volunteering Associations in the Post-Retirement Transition: The Case Study of AUSER (Associazione per l'autogestione dei servizi e la solidarietà)

Giovanna Del Gobbo, Cristina Banchi

University of Florence, Italy

Public attitudes towards ART and its social determinants: evidence from an ad-hoc survey in Italy

Ester Lazzari², Valentina Tocchioni¹, Marco Cozzani¹, Daniele Vignoli¹

1: University of Florence, Italy; 2: University of Vienna

Family expectations, social capital and perceived Well-Being in the transition to retirement

Donatella Bramanti¹, Luisa Errichiello², Greta Falavigna³, Sara Nanetti¹

1: Università Cattolica - Milano, Italy; 2: CNR- ISMed; 3: CNR- IRCrES

Changing family trajectories and their impact on men’s and women’s mental health in midlife. The case of 1958 and 1970 British cohorts

Danilo Bolano¹, Roberta Rutigliano², Anna Barbuscia², Maria Sironi³

1: University of Florence, Italy; 2: University of the Basque Country; 3: University of Padua

Is “living apart together” a real advantage for patients consulting for sexual dysfunction? A cohort study from a Florentine population

Clotilde Sparano¹, Giovanni Corona², Giulia Rastrelli³, Linda Vignozzi³, Daniele Vignoli⁴, Mario Maggi¹

1: University of Florence, Italy; 2: Endocrinology Unit, Azienda USL Bologna, Bologna, Italy; 3: Andrology, Women’s Endocrinology and Gender Incongruence Unit, "Mario Serio", Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy; 4: Department of Statistics, Computer Science, Applications, University of Florence, Florence, Italy

Enhancement of attentional skills for driving in healthy older adults: effects of the cognitive training DRIVEWIN 3.0 that combines virtual reality and neurostimulation

Ilaria Baroni^1,2, Carlotta Lega³, Laura Veronelli^1,2, Simone Fontana¹, Leonardo Pantoni², Marco Feligioni², Alessio Facchin⁴, Roberta Daini¹

1: University of Milano-Bicocca, Italy; 2: Casa di Cura Igea, Italy; 3: University of Pavia, Italy; 4: University of Magna Graecia of Catanzaro, Italy

Feasibility and User Experience of Tablet-Based Cognitive Stimulation in Hospitalized Older Adults: Preliminary Results from the OPTIMAge-IT Trial

Chukwuma Okoye¹, Maria Cristina Ferrara¹, Wenxiang Guo¹, Beatrice Tonus¹, Lorenzo Lodovici¹, Elena Carlino², Lucia Muglia³, Alberto Finazzi¹, Guido Ferratini⁴, Danny Bassis⁵, Giuseppe Dario Testa⁴, Gianluca Bianco⁶, Filippo Niccolai², Valeria Calsolaro², Noemi Pardini², Eleonora Cucini¹, Annalisa Cozza³, Elvira Clausi⁷, Carmen Ruberto⁸, Lorella Lambertucci⁴, Maddalena Minelli⁵, Roberta Daini¹, Agostino Virdis², Filippo Fimognari⁷, Alessandra Marengoni⁶, Giovanni Ruotolo⁸, Andrea Corsonello³, Andrea Ungar⁴, Fabio Guerini⁵, Giuseppe Bellelli¹

1: University of Milano-Bicocca, Milan, Italy; 2: Department of Clinical and Experimental Medicine, University of Pisa, Italy; 3: Unit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy; 4: Department of Experimental and Clinical Medicine, University of Florence, Italy; 5: Department of Medicine, S. Anna Hospital, Brescia, Italy; 6: Department of Clinical and Experimental Sciences, University of Brescia, Italy; 7: Unit of Geriatrics, Departmemt of Internal Medicine "Annunziata-Mariano Santo-S. Barbara" Hospital, Cosenza, Italy.; 8: Geriatric Unit Center for Cognitive Disorders and Dementia, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy

Toward Self-Monitoring Healthcare: An Open Platform Ultraportable Ultrasound System.

Valentino Meacci, Lorenzo Castrignano, Paolo Verdi, Giulio Bonciani, Piero Tortoli, Enrico Boni, Alessandro Ramalli

University of Florence, Italy

Impedance Control for a Modified EduExo Upper Limb Exoskeleton in ALS Rehabilitation

Hamidreza Heidari, Paolino De Risi, Fanny Ficuciello

Università degli Studi di Napoli Federico II, Italy

Migrants and Ageing in Italy: A Multifarious Phenomenon

Daniela Carrillo, Patrizia Farina

university of Milan Bicocca, Italy

Enhancing health literacy to support family dementia caregivers: a community-based group intervention in primary care

Claudia Biagi¹, Chiara Milani¹, Claudia Rosi¹, Rachele Mei¹, Riccardo Barucci², Enrico Benvenuti², Giulia Naldini³, Lorenzo Baggiani³, Chiara Lorini¹, Guglielmo Bonaccorsi¹

1: Department of Health Sciences, University of Florence, Italy; 2: Geriatric Unit, Azienda USL Toscana Centro, Italy; 3: Department of Community Healthcare Network, Azienda USL Toscana Centro, Italy

Assisting Dementia caregivers through AI-CARE: a study protocol for usability

Danilo Atripaldi^1,2, Fabio Matascioli¹, Ludovico Piccolo¹, Nadia Conte¹, Agostino Borroso¹, Ilaria Chirico³, Riccardo Pronzato⁴, Sara Trolese³, Rabih Chattat³

1: TAMLab - Social Enterprise, Naples, Italy; 2: Department of Advanced Medical and Surgical Studies, University of Campania “Luigi Vanvitelli”, Naples, Italy; 3: Department of Psychology, University of Bologna, Italy; 4: Department of Sociology and Business Law, University of Bologna, Italy

The co-design and development of an e-learning platform for informal, formal and migrant caregivers of people with dementia: the AGE-IT project

Rabih Chattat¹, Sara Trolese¹, Sara Santini², Georgia Casanova², Serena Cancellieri², Antonella Golino³, Daniela Grignoli³, Veronica Moretti¹, Riccardo Pronzato¹, Ilaria Chirico¹

1: University of Bologna, Italy; 2: IRCCS INRCA National Institute of Health and Science on Ageing, Centre for Socio-Economic Research on Aging, Ancona, Italy; 3: University of Molise, Campobasso, Italy

Preliminary Insights from IN-TEMPO: A Multicenter Randomized Controlled Trial on Personalized Multidomain Interventions for Healthy Aging

Luca Cuffaro^1,2, Federico Emanuele Pozzi^1,2, Giovanni Isgrò^1,2, Gessica Sala^1,2, Carlo Ferrarese^1,2

1: School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 2: Milan Center for Neuroscience (Neuro-MI), University of Milano-Bicocca, Milan, Italy

Blood biomarkers for monitoring the impact of multidomain interventions on age-related cognitive and functional decline

Gessica Sala^1,2, Simona Andreoni^1,2, Chiara Bazzini^1,2, Elisa Conti^1,2, Chiara Paola Zoia^1,2, Luca Cuffaro^1,2,3, Federico Emanuele Pozzi^1,2,3, Lucio Tremolizzo^1,2,3, Maria Pia Longhese⁴, Giovanni Messina⁴, Cristina Airoldi^2,4, Ferdinando Chiaradonna^2,4, Luca Moretti⁴, Antonino Natalello^2,4, Ivan Orlandi⁴, Carlo Ferrarese^1,2,3

1: School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 2: Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milan, Italy; 3: Department of Neurology, Fondazione IRCCS “San Gerardo dei Tintori”, Monza, Italy; 4: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

Decoding the Epigenetic Clock: Long-Term Predictive Power of DNA Methylation for Age Estimation

Ersilia Paparazzo^1,2, Teresa Serra Cassano^1,3, Mirella Aurora Aceto¹, Vincenzo Lagani⁴, Pierluigi Mercatante^1,3, Silvia Fain¹, Antonella La Russa⁵, Luca Soraci⁶, Andrea Corsonello⁷, Francesco De Rango¹, Giuseppe Passarino¹, Alberto Montesanto¹

1: Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy; 2: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy; 3: University of Florence, Department of Statistic, Computer Science and Application, DiSIA, Viale Morgagni, 59, 50134, Florence (FI), Italy; 4: Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal 23952, Saudi Arabia; Institute of Chemical Biology, Ilia State University, Tbilisi 0162, Georgia; 5: Nephrology Unit, Department of Health Sciences, Magna Graecia University, Catanzaro 88100, Italy; 6: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy.; 7: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy; Department of Pharmacy, Health and Nutritional Sciences, School of Medicine and Digital Technologies, University of Calabria, Arcavacata di Rende, Italy

Aberrant TCR intracellular trafficking drives T cell dysfunction in immuno-senescence

Andrea Graziani^1,2, Raluca Minea¹, Alessia Labate¹, Giulia Rossino^1,2, Sabrina Mula¹, Emma Colautti¹, Andrea Toscano¹, Camilla Racca¹, Valeria Malacarne^1,2

1: Università di Torino, Molecular Biotechnology Center, Department of Molecular Biotechnology and Healths Sciences, Italy; 2: Università del Piemonte Orientale, Dept. of Translational Medicine

Dissecting evolutionary stress-adaptive adaptations in the hyper-longevous bats to devise novel anti-aging approaches.

Andrea Giacomo Locatelli^1,2, Roberto Pagliarini³, Martina Uggè⁴, Maria Materozzi¹, Ugo Orfanelli¹, Davide Stefanoni¹, Marta Roggiani¹, Massimo Resnati¹, Simone Cenci^1,2

1: Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milano, Italy; 2: Università Vita-Salute San Raffaele, Milano, Italy; 3: Department of Mathematics, Informatics and Physics Sciences, University of Udine, Udine, Italy; 4: Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milano, Italy

Obesity as driver of premature immune senescence

Valeria Mazzone¹, Annamaria Szabò¹, Antonella Desiderio², Antonietta Liotti^2,3, Rosa Spinelli², Daria Marcogiuseppe¹, Anna D'Amore⁴, Marco Milone⁴, Gregory Alexander Raciti², Francesco Beguinot², Claudia Miele¹, Veronica De Rosa¹

1: Istituto degli Endotipi in Oncologia, Metabolismo e Immunologia “G. Salvatore” (IEOMI)-CNR, Napoli, Italy; 2: Dipartimento di Scienze Mediche Traslazionali (DISMET) Università degli Studi di Napoli "Federico II", Napoli, Italy; 3: Centro Interdipartimentale di Ricerca in Scienze Immunologiche di base e cliniche (CISI), Università degli Studi di Napoli "Federico II", Napoli, Italy; 4: Dipartimento di Medicina e Chirurgia Clinica, Università degli Studi di Napoli "Federico II", Napoli, Italy

Mortalità e salute: dati, concetti e metodi nel percorso di un protagonista della demografia

Graziella Caselli, Viviana Egidi

Sapienza Università di Roma

Mobilità e lavoro di fronte alle sfide dell'invecchiamento: il contributo di Antonio Golini

Corrado Bonifazi, Giuseppe Gesano

IRPPS CRN

Verso una sintesi delle dinamiche territoriali: il malessere demografico

Annalisa Busetta¹, Sara Basso²

1: University of Palermo; 2: Istat

Geriatria e invecchiamento della popolazione

Fabrizia Lattanzio

Inrca

New technologies and old population: exploring legal challenges in a changing society

Claudia Morgana Cascione

University of Bari Aldo Moro, Italy

AI-Supported Home Adaptation for Older Adults: Insights from a Qualitative Study with Architects

Atieh Mahroo¹, Federica Romagnoli², Daniele Spoladore¹, Tiziana Ferrante², Marco Sacco¹, Teresa Villani²

1: National Research Council - Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing (CNR-STIIMA); 2: Sapienza University of Rome - Department of Planning, Design and Technology of Architecture (PDTA)

A Persona approach for the user-centred design of IT-enabled health and social care services.

Vincenzo De Luca¹, Michele Virgolesi¹, Alessandra Cuomo², Daniela Lemmo³, Mariangela Perillo⁴, Lorenzo Mercurio¹, Erminia Attaianese⁴, Enrica Menditto⁵, Annamaria Colao², Guido Iaccarino², Maddalena Illario¹

1: Department of Public Health, Federico II University of Naples, Italy; 2: Department of Clinical Medicine and Surgery, Federico II University of Naples, Italy; 3: Department of Human Sciences, Federico II University of Naples, Italy; 4: Department of Architecture, Federico II University of Naples, Italy; 5: Department of Pharmacy, Federico II University of Naples, Italy

Exploring the impact of Ambient Assisted Living for older people on caregiver burden: a systematic literature review.

Georgia Casanova, Marco Socci, Diletta Cicconi, Anita Ambrosi, Cristina Gagliardi

IRCCS INRCA - National Institute of Health and Science on Ageing, Centre for Socio-Economic Research on Ageing, Ancona, Italy

Green transition and labour market dynamics of older workers

Danilo Cavapozzi, Federico de Luca

Università Ca' Foscari Venezia, Italy

Childbirth and Income Within Couples: A Dyadic Analysis from Administrative Data in Tuscany

Elisa Brini¹, Carlos J. Gil-Hernández¹, Raffaele Guetto¹, Marialuisa Maitino², Letizia Ravagli², Daniele Vignoli¹

1: University of Florence, Department of Statistics, Computer Science, Applications ‘G. Parenti’; 2: Istituto Regionale per la Programmazione Economica della Toscana (IRPET)

Accidents at work: evidence from an unanticipated increase in retirement age

Manuel Alarcon Serrano¹, Chiara Ardito¹, Elena Cottini², Gloria Moroni³

1: Joint Research Centre, Ispra; 2: Department of Economics and Finance, Universit`a Cattolica del Sacro Cuore; 3: Ca Foscari University of Venice, Italy

Working Longer, Living Longer? Retirement Timing, Migration Background and Mortality in Sweden

Eleonora Trappolini¹, Sven Drefahl²

1: Sapienza University of Rome, Italy; 2: Stockholm University, Sweden

Measuring Changes in Risk Preferences Over the Life Cycle: Experimental Evidence from Economics and Psychology

Pablo Marcos-Prieto, Erica Ordali, Chiara Rapallini

University of Florence, Italy

Why Do Households Save and Work?

Margherita Borella¹, Mariacristina De Nardi^2,4, Fang Yang³, Johanna Torres Chain²

1: University Cà Foscari Venice, University of Torino, Italy; 2: University of Minnesota; 3: Federal Reserve Bank of Dallas; 4: Federal Reserve Bank of Minneapolis

The Risk of Work Related Accidents at Older Ages

Elena Cottini¹, Michele Maccarini¹, Gloria Moroni²

1: Università Cattolica del Sacro Cuore, Italy; 2: Università Ca' Foscari Venezia, Italy

Working Conditions and Health Over the Life-cycle: Evidence From Europe

Paolo Micera¹, Claudio Lucifora¹, Michele Belloni²

1: Università Cattolica del Sacro Cuore, Italy; 2: Università degli studi di Torino, Italy

The MOVE Project: Study Design and Baseline Characterization of a Longitudinal Trial on Cognitive and Physical Decline

Alessandra Dodich, Caterina Dapor, Giulia Ellena, Marco Pietro Parente, Elena Zambon, Jorge Jovicich, Costanza Papagno

Center for Mind/Brain Sciences, CIMeC, University of Trento, Rovereto, Italy

Impact of Inactivity on Neuromuscular Health

Marco Narici^1,2, Ornella Caputo¹, Fabio Sarto¹, Eugenia Motanova¹, Martino Franchi², Bostjan Simunič², Mladen Gasparini³, Rado Pišot²

1: University of Padova, Italy; 2: ZRS Science Research Centre, Koper, Slovenia; 3: Izola General Hospital. Izola, Slovenia

Novara Cohort Study (NCS): A mixed-methods analysis of participant impact and experience

Riccardo Tucci¹, Silvia Caristia², Silvia Vittoria Cracas³, Giulia Garro⁴, Marco Martorana⁵, Erica Viola⁶, Chiara Aleni⁷, Jacopo Venetucci⁸, Lucrezia Capuzzi⁹, Vittoria Colombo¹⁰, Valeria Bettio¹¹, Fabrizio Faggiano¹², Daniela Capello¹³

1: Università del Piemonte Orientale, Italy; 2: Università del Piemonte Orientale, Italy; 3: Università del Piemonte Orientale, Italy; 4: Università del Piemonte Orientale, Italy; 5: Università degli studi di Firenze, Italy; 6: Università del Piemonte Orientale, Italy; 7: Astra Zeneca; 8: Università del Piemonte Orientale, Italy; 9: Università del Piemonte Orientale, Italy; 10: Università del Piemonte Orientale, Italy; 11: Università del Piemonte Orientale, Italy; 12: Università del Piemonte Orientale, Italy; 13: Università del Piemonte Orientale, Italy

Clinical impact and prognostic value of Alzheimer’s disease pathophysiology in the very old.

Chiara Ceriello .^1,3,5, Olga H. Torres^1,3,5, Daniel Alcolea^2,3,4,5, Ignacio Illan^2,3,4,5

1: Geriatric Unit, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025, Barcelona, Spain; 2: Sant Pau Memory Unit, IR SANT PAU, Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain; 3: Institut de Recerca Sant Pau (IR SANT PAU), Sant Quintí 77-79, 08041, Barcelona, Spain; 4: Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, 28029, Spain; 5: Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain

Quercetin induces senolysis of doxorubicin-induced senescent fibroblasts by reducing autophagy, preventing their pro-tumour effect on osteosarcoma cells

Elisa Bientinesi, Sara Ristori, Gianmarco Bertoni, Matteo Lulli, Daniela Monti

Department of Experimental and Clinical Biomedical Sciences, University of Florence, Italy

Exploring the Synergistic Effect of a Senolytic Compound and a Probiotic on Healthspan and Lifespan in Aged Mice

Serena Marcozzi¹, Giorgia Bigossi¹, Maria Elisa Giuliani¹, Giovanni Lai¹, Marco Malavolta^1,2

1: IRCCS INRCA, Ancona, Italy; 2: Università Politecnica Delle Marche, Ancona, Italy.

Carnitine network and SASP: role of membrane transporters from SLC family

Mariafrancesca Scalise¹, Francesca Barone¹, Lara Console¹, Michele Galluccio¹, Annamaria Tonazzi², Nicola Giangregorio², Lorena Pochini^1,2, Cesare Indiveri^1,2

1: University of Calabria, Italy; 2: IBIOM-CNR, Bari Italy

A20 and TNIP3 attenuate NF-κB – mediated paracrine responses to hypoxia/hyperglycemia-induced endothelial senescence

Lara Russo, Serena Babboni, Serena Del Turco, Giuseppina Basta

Consiglio nazionale delle ricerche- Istituto di Fisiologia Clinica, Italy

Role of the TGN transport machinery in the regulation of SASP-components transport and secretion.

Rosaria Di Martino, Daniela Corda, Alberto Luini

Istituto degli Endotipi in Oncologia, Metabolismo ed Immunologia, Consiglio Nazionale delle Ricerche, Italy

Effects of Chemotherapy-Induced Golgi Alterations and Exploiting Senescence for Cancer Therapy

Fabiola Mascanzoni, Inmaculada Ayala, Daniela Spano, Roberta Iannitti, Antonino Colanzi

CNR, IEOMI Italy

A cytokine-based inflammaging score improves frailty-based prediction of long-term mortality in older adults.

Matilde Sbriscia¹, Sonia Fantone¹, Mirko Di Rosa², Francesca Marchegiani³, Rina Recchioni³, Giulia Matacchione³, Chiara Giordani³, Francesco Piacenza¹, Roberta Giacconi¹, Davide Gentilini^4,5, Luciano Calzari⁴, Carlo Forunato¹, Gretta Veronica Badillo Pazmay¹, Monia Cecati¹, Sara Caccese⁶, Emanuele Francini³, Rosanna Maniscalco¹, Maurizio Cardelli¹, Elena Tortato⁷, Federica Lenci⁸, Yuri Rosati⁹, Maurizio Burattini¹⁰, Roberto Antonicelli¹¹, Andrea Corsonello^12,13, Luca Soraci¹², Leonardo Biscetti¹⁴, Massimiliano Fedecostante¹⁵, Riccardo Sarzani^16,17, Marco Malavolta^1,16, Tiziana Casoli¹⁸, Maria Conte¹⁹, Antonio Domenico Procopio^3,16, Fabrizia Lattanzio⁶, Anna Rita Bonfigli⁶, Antonio Cherubini^15,16, Claudio Franceschi²⁰, Jacopo Sabbatinelli^3,16, Fabiola Olivieri^1,16

1: Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; 2: Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 3: Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy; 4: Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Italy; 5: Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; 6: Scientific Direction, IRCCS INRCA, Ancona, Italy; 7: Diabetology Unit, IRCCS INRCA, Ancona, Italy; 8: Unit of Nephrology and Dialysis, IRCCS INRCA, Ancona, Italy; 9: Respiratory Medicine, IRCCS INRCA, Osimo, Italy; 10: Internal Medicine, IRCCS INRCA, Osimo, Italy; 11: Cardiology Unit, IRCCS INRCA, Ancona, Italy; 12: Unit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy; 13: Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy; 14: Neurology Unit, IRCCS INRCA, Ancona, Italy; 15: Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy; 16: Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; 17: Internal Medicine and Geriatrics, 'Hypertension Excellence Centre' of the European Society of Hypertension, Società Italiana per lo Studio dell'Aterosclerosi (SISA) LIPIGEN Centre, IRCCS INRCA, Ancona, Italy; 18: Center for Neurobiology of Aging, IRCCS INRCA, Ancona, Italy; 19: Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; 20: Institute of Biogerontology, Lobachevsky State University, Nizhny Novgorod, Russia

Advanced microphysiological systems to evaluate pharmacological interventions in vitro CKD models

Alessandra Calogiuri¹, Laura Blasi², Paola Pontrelli³, Gianvito Caggiano⁴, Alessandra Stasi⁵, Elisa Sciurti⁶, Daniele Bellisario⁷, Vanessa Esposito⁸, Flavio Casino⁹, Pietro Aleardo Siciliano¹⁰, Luca Nunzio Francioso¹¹

1: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 2: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 3: Nephrology, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.; 4: Nephrology, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.; 5: Nephrology, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.; 6: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 7: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 8: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 9: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 10: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 11: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy

Exploring the Muscle–Brain Axis: Associations Between Neurodegeneration Biomarkers, Sarcopenia, and Function in Older Adults – Preliminary Results from the OPA Study

Marina De Rui¹, Chiara Ceolin¹, Eleonora Fiorenzato², Giulia Musso³, Cristina Simonato¹, Silvia Sturani¹, Adele Ravelli¹, Francesca Vianello², Laura Nasi², Simone Cauzzo², Sabrina Pigozzo¹, Maria Devita¹, Alessandra Coin¹, Gabriella Milan⁴, Catia Pilon⁴, Luca Busetto⁴, Angelo Antonini², Giuseppe Sergi¹

1: Geriatric Unit, Department of Medicine (DIMED), University Hospital of Padua, Padua, Italy; 2: Parkinson's Disease and Movement Disorders Unit, Center for Rare Neurological Diseases (ERN-RND), Department of Neurosciences, University of Padova, Padova, Italy; 3: Department of Laboratory Medicine, Department of Medicine (DIMED), University of Padua, Padua; 4: Clinica Medica 3, Department of Medicine (DIMED), University of Padua, Padua

Effects of Paget’s disease of bone-associated ZNF687 and PFN1 mutations on hematopoietic cell heterogeneity and differentiation in the context of aging

Sharon Russo, Federica Scotto di Carlo, Fernando Gianfrancesco

Institute of Genetics and Biophysics, Italy

Portable Surface Electromyography System for Sarcopenia Detection

Anna Maria Carluccio, Andrea Manni, Gabriele Rescio, Andrea Caroppo, Pietro Aleardo Siciliano, Alessandro Leone

National Research Council of Italy, Instiute for Microelectronics and Microsystems, Lecce, Italy

Evaluating Musculoskeletal Models and IMU Configurations for Reach-to-Grasp Biomechanics in Aging

Pietro Benvenuti

Università degli Studi di Firenze, Italy

Parallel semantic reading of multiple words in aging

Matilde Menghini¹, Silvia Primativo², Valentina Bandiera², Laura Veronelli¹, Carlotta Lega¹, Luisa Girelli¹, Fabrizio Zeri¹, Roberta Daini¹

1: Università degli Studi di Milano-Bicocca, Italy; 2: Università LUMSA

IDENTIFICATION AND QUANTIFICATION OF MULTIDIMENSIONAL FRAILTY IN ELDERLY PATIENTS IN DIFFERENT CARE SETTINGS (Fra-SET)

Pasquale Abete¹, Francesco Curcio¹, Francesco Cacciatore¹, Gesualda Bruno¹, Antonio Cittadini², Michele Arcopinto², Andrea Salzano², Nicola Vargas³, Elisa Salsano³, Oriana Rossi³, Gaetano Gargiulo⁴, Umberto Mazzarelli⁴, Aniello Sottolano⁴, Antonio Petrocelli⁵, Lucia Agrelli⁵, Gina Varricchio⁶, Raffaele Pagliuca⁶, Luisa Aran⁶, Pasquale Morella⁷, Antonio Magliocca⁷, Mariano Carafa⁸, Mattia De Furio⁸

1: Department of Translational Medical Sciences, University of Naples Federico II, Italy; Division of Sub-intensive Medical Therapy, AOU Federico II, Naples, Italy; 2: Division of Rehabilitation and Metabolic Internal Medicine AOU Federico II, Naples, Italy; 3: Division of Geriatrics - AORN San Giuseppe Moscati, Avellino, Italy; 4: Division of Internal Medicine, AOU San Giovanni di Dio e Ruggi di Aragona, Salerno, Italy; 5: Division of Emergency Medicine AOU San Giovanni di Dio e Ruggi di Aragona, Salerno, Italy; 6: Division of Geriatrics, AO Sant'Anna e San Sebastiano, Caserta, Italy; 7: Division of Internal Medicine 3, AORN Antonio Cardarelli, Naples, Italy; 8: Division of Internal Medicine DEA and clinical Complexity, AORN Antonio Cardarelli, Naples, Italy

Health Literacy and Early Frailty Detection in Primary Care: A Community-Based Observational Study

Guglielmo Bonaccorsi¹, Claudia Biagi¹, Chiara Milani¹, Diletta Buresta¹, Fiorenza Wetzel Cabrera¹, Riccardo Barucci², Enrico Benvenuti², Lorenzo Baggiani², Marco Nerattini³, Chiara Lorini¹

1: University of Florence, Italy, Italy; 2: AUSL Toscana Centro; 3: Società della Salute Firenze

Differential Impact of Frailty on Neurodegenerative, Cardiometabolic, and Cancer Outcomes

Augusto Di Castelnuovo¹, Simona Costanzo^1,2, Francesca Bracone¹, Alessandro Gialluisi^1,3, Marialaura Bonaccio¹, Teresa Panzera¹, Chiara Cerletti¹, Maria Benedetta Donati¹, Giovanni de Gaetano¹, Licia Iacoviello^1,3

1: IRCCS Neuromed, Pozzilli, Italy; 2: University of Insubria, Varese, Italy; 3: LUM University, Casamassima, Italy

Parallel Burdens of Aging: Disentangling the Impact of Frailty and Comorbidity on Long-Term Survival in the FRASNET Cohort

Patrizia Rovere-Querini^1,2, Sarah Damanti^1,2, Martina Mallus^1,2, Laura Zagato^1,3, Lorena Citterio^1,3, Paolo Manunta^1,3, Chiara Lanzani^1,3

1: Università Vita Salute San Raffaele, Italy; 2: Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 3: Nephrologic Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Frailty and Multimorbidity in Older Inpatients: A Comparative Analysis of Quantitative and Qualitative Predictors of In-Hospital Outcomes

Luca Soraci¹, Mirko Di Rosa², Andrea Corsonello^1,3, Massimiliano Fedecostante⁴, Sarah Damanti⁵, Rosa Liperoti⁶, Licia Iacoviello⁷, Pasquale Abete⁸, Riccardo Calvani⁹, Fabrizia Lattanzio¹⁰, Antonio Cherubini^4,11

1: Unit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy; 2: Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 3: Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy; 4: Geriatria, Accettazione Geriatrica e Centro di Ricerca per l'Invecchiamento, IRCCS INRCA, Ancona, Italy; 5: Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 6: Department of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, Rome, Italy; 7: Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli (IS), Italy; 8: Department of Translational Medical Sciences (DISMET), Federico II University, Naples, Italy; 9: Fondazione Policlinico Universitario A Gemelli IRCCS, Largo Agostino Gemelli 8, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy; 10: Scientific Direction, IRCCS INRCA, Ancona, Italy; 11: Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy

Integrating Clinical and Biological Indices to Enhance Frailty Detection: Insights from the Novara Cohort Study

Silvia Vittoria Cracas, Giulia Garro, Jacopo Venetucci, Annamaria Antona, Marco Varalda, Valentina Bettio, Roberta Rolla, Luca Briacca, Chaitanya Reddy Kankara, Fabrizio Faggiano, Daniela Capello

Università del Piemonte Orientale, Italy

AQP4 protein and Antisense lncRNAs expression in Brain development and aging

Onofrio Valente, Alessandra Rombolà, Pasqua Abbrescia, Claudia Palazzo, Antonio Frigeri

Department of Translational Biomedicine and Neuroscience School of Medicine, University of Bari Aldo Moro,

HIV reservoir and premature aging: risk factors for aging-associated illnesses in adolescents and young adults with perinatally acquired HIV

Maria Raffaella Petrara^1,2, Elena Ruffoni¹, Francesco Carmona¹, Ilaria Cavallari¹, Sandra Zampieri^3,4, Marzia Morello¹, Paola Del Bianco⁵, Osvalda Rampon⁶, Nicola Cotugno⁷, Paolo Palma⁷, Paolo Rossi⁷, Carlo Giaquinto⁶, Silvia Giunco^1,2, Anita De Rossi^1,2

1: Immunology and Molecular Oncology Diagnostics, Veneto Institute of Oncology IOV–IRCCS, Padova, Italy; 2: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; 3: Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; 4: Department of Biomedical Sciences, University of Padova, Padova, Italy; 5: Clinical Research Unit, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy; 6: Department of Women’s and Children’s Health, Division of Pediatric Infectious Diseases, University of Padova, Padova, Italy; 7: Clinical and Research Unit of Clinical Immunology and Vaccinology, Bambino Gesu` Children’s Hospital, IRCCS, Roma, Italy

Exploring the extrinsic control of macrophage plasticity in skeletal muscle regeneration

Ombretta Guardiola^1,2, Monica Nicolau³, Angela Gambardella^1,2, Gennaro Andolfi^1,2, Carmela Dell'Aversana^4,5, Lucia Altucci^6,7,8, Chiara Nicoletti³, Gabriella Minchiotti^1,2

1: Stem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR, Naples, 80131, Italy; 2: Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR, Naples, 80131, Italy; 3: Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA; 4: Department of Medicine and Surgery, LUM University, Casamassima (BA), Italy; 5: Istituto degli Endotipi in Oncologia, Metabolismo e Immunologia "Gaetano Salvatore", CNR Naples, Italy; 6: Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 7: BIOGEM, Ariano Irpino, Ariano Irpino, AV, 83031, Italy; 8: Program of Medical Epigenetics, Vanvitelli Hospital, Naples, Italy

Human volatilome insights: biomarkers for chronic kidney disease and associated cognitive decline

Giulia My¹, Angiola Forleo¹, Alessandra Aloisi¹, Maria Teresa Cimmarusti², Marco Fiorentino², Alessandra Stasi², Rossana Franzin², Monica Campioni², Stefania Rotella², Gesualdo Loreto², Simonetta Capone¹

1: Institute for Microelectronics and Microsystems (CNR-IMM), Via Monteroni, Campus Ecotekne, Lecce, Italy, Italy; 2: Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari

Impact of Fall-Risk-Increasing Drugs on accidental falls and injuries among community-dwelling older adults: an Italian case-control study

LARA PERRELLA^1,2, ELENA OLMASTRONI^3,4, SARA MUCHERINO^1,2, VALENTINA ORLANDO^1,2, MANUELA CASULA^3,4, ENRICA MENDITTO^1,2

1: CIRFF, Center of Pharmacoeconomics and Drug Utilization Research, University of Naples Federico II, Naples, Italy; 2: Department of Pharmacy, University of Naples Federico II, Naples, Italy; 3: Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy; 4: IRCCS MultiMedica, Sesto San Giovanni (Milan), Italy

Views of Aging and Self-Care among Older Adults with Non-Communicable Diseases

Fabrizio Mezza¹, Daniela Lemmo¹, Maria Francesca Freda¹, Maddalena Illario², Angela Palomba², Antonio Picone², Carlo Ruosi², Guido Iaccarino³

1: Department of Humanistic Studies, University of Naples Federico II, Italy; 2: Department of Public Health, University of Naples Federico II, Italy; 3: Department of Clinical Medicine and Surgery

Electrocardiography-based heart aging: a novel potential index for risk stratification in the general population

Antonietta Pepe^1,2, Augusto Di Castelnuovo², Simona Costanzo^2,3, María Loreto Muñoz Venegas², Teresa Panzera², Chiara Cerletti², Maria Benedetta Donati², Giovanni de Gaetano², Licia Iacoviello^1,2, Alessandro Gialluisi^1,2

1: Department of Medicine and Surgery, LUM University, Casamassima, Italy; 2: Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; 3: EPIMED Research Center, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Is there an effect of autonomic nervous system on the association between epicardial adipose tissue and cognitive function in the elderly?

Laura Petraglia, Martina Valentino, Maria Perrotti, Maria Pia Calligari, Luca Corbia, Carmine Dello Russo, Stefano Maisto, Giuseppe Rengo, Dario Leosco, Grazia Daniela Femminella

Department of Translational Medical Sciences, University of Naples Federico II

Study of Mitochondrial function in cardiac metabolism of HFpEF

Cristina Gatto, Maria Rosaria Rusciano, Albino Carrizzo, Paola Di Pietro, Luigi Schiavo, Daniele Di Napoli, Ivano Esposito, Valentina D'Agostino, Carmine Vecchione, Michele Ciccarelli

University of Salerno, Italy-Department of Medicine,Surgery and Dentistry

Death by Waiting: Treatment Delays, Emergency Department Congestion and Patients' Outcomes

Jan Mazza, Matteo Lippi Bruni, Cristina Ugolini, Rossella Verzulli

Università di Bologna, Italy

Title: Future Thinking exercise on Aging in Place: A Backcasting by Spoke 5 Experts Sub-title : Assumptions, Framework and Criticalities from a Collective Intelligence Experience

Cristina Gagliardi

IRCCS INRCA, Italy

Investigating the Determinants of Welfare Expenditure for Older Adults in Italian Municipalities

Giuliano Resce¹, Nicola Caravaggio¹, Idola Francesca Spanò¹, Giovanni Lamura², Gabriele Morettini²

1: University of Molise, Italy; 2: INRCA

An Actor-Centered Theoretical Tool for Caregiver Policy Analysis: Comparative Evidence from Italian Metropolitan Cities

Giovanni Amerigo Giuliani, Marco Albertini, Federico Toth, Lavinia De santis, Eva Bei

Univeristà di Bologna, Italy

Interprofessional collaboration: the role of primary care physicians and nurses for a successful chronic disease management program

Marta Giachello, Matteo Lippi Bruni, Cristina Ugolini, Rossella Verzulli

University of Bologna, Italy

DNA methylation signature in blood samples from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) study

Mirella Aurora Aceto¹, Elene Kenia², Teresa Serra Cassano^1,3, Francesco Bruno⁴, Paolo Abbondio⁵, Pierluigi Mercatante^1,3, Silvia Fain¹, Ersilia Paparazzo^1,6, Vincenzo Lagani⁷, Francesco De Rango¹, Giuseppe Passarino¹, Alberto Montesanto¹

1: Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.; 2: School of Natural Sciences and Medicine, Ilia State University, Tbilisi, Georgia.; 3: University of Florence, Department of Statistic, Computer Science and Application, DiSIA, Viale Morgagni, 59, 50134, Florence (FI), Italy.; 4: Faculty of Social and Communication Sciences, Universitas Mercatorum, Piazza Mattei 10, Rome, 00186 Italy.; 5: Laboratory of Ancient DNA, Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121 Ravenna, Italy.; 6: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy.; 7: Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal 23952, Saudi Arabia; Institute of Chemical Biology, Ilia State University, Tbilisi 0162, Georgia.

Exploring epigenetic drift in Alzheimer’s disease by next generation methylation array

Teresa Serra Cassano^1,2, Ersilia Paparazzo^1,3, Mirella Aurora Aceto¹, Vincenzo Lagani⁴, Davide Gentilini^5,6, Davide Sacco⁵, Francesco De Rango¹, Francesca Cavalcanti⁷, Raffaele Maletta⁸, Giuseppe Passarino¹, Alberto Montesanto¹

1: Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy; 2: University of Florence, Department of Statistic, Computer Science and Application, DiSIA, Viale Morgagni, 59, 50134, Florence (FI), Italy; 3: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy.; 4: Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal 23952, Saudi Arabia; Institute of Chemical Biology, Ilia State University, Tbilisi 0162, Georgia.; 5: Department of Brain and Behavioral Sciences, Università di Pavia, Pavia, Italy.; 6: Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Milan, Italy.; 7: Institute for Biomedical Research and Innovation (IRIB), Italian National Research Council (CNR), Mangone, Italy.; 8: Regional Neurogenetic Centre (CRN), Department of Primary Care, Azienda Sanitaria Provinciale Di Catanzaro, Lamezia Terme, CZ, Italy.

Strategies to study the biology of aging before Alzheimer's disease onset

Lorenzo Neri, Alessia Vignoli, Marina Bacci, Alessandra Bigi, Benedetta Mannini, Andrea Morandi, Leonardo Tenori, Fabrizio Chiti

Università degli Studi di Firenze, Italy

Exploring the influence of multiple exposome layers on Alzheimer’s Disease risk: findings from the Moli-sani cohort

Antonietta Pepe^1,2, María Loreto Muñoz Venegas², Federica Santonastaso³, Simona Costanzo^2,4, Maria Ilenia De Bartolo^5,6, Americo Bonanni², Augusto Di Castelnuovo², Alfonso Di Costanzo⁷, Nicola Pirastu³, Matteo Renzi⁸, Giovanni Veronesi⁴, Gaetano Zazzaro⁹, Francesco Gianfagna⁴, Alfredo Berardelli^5,10, Maria Benedetta Donati², Giovanni de Gaetano², Nicole Soranzo^3,11,12, Licia Iacoviello^1,2, Alessandro Gialluisi^1,2

1: Department of Medicine and Surgery, LUM University, Casamassima, Italy; 2: Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; 3: Human Technopole, Milan, Italy; 4: EPIMED Research Centre, Department of Medicine and Surgery, University of Insubria, Varese, Italy; 5: IRCCS NEUROMED, Pozzilli, Italy; 6: Department of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza University of Rome, Rome, Italy; 7: Centre for Research and Training in Medicine of Aging, Department of Medicine and Health Science "V. Tiberio," University of Molise, Campobasso, Italy; 8: Department of Epidemiology, Lazio Region Health Service/ASL Roma 1, Rome, Italy; 9: CIRA-Italian Aerospace Research Centre, Capua, Italy; 10: Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy; 11: British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; 12: Human Genetics Department, Wellcome Sanger Institute (WT), Hinxton, UK

The performance of a plasma biomarker panel in detecting cognitive decline in Alzheimer's disease and its preclinical stages.

Assunta Ingannato^1,2, Silvia Bagnoli^1,2, Katia Maria Giametta¹, Elisa Marcantelli¹, Giulia Giacomucci¹, Chiara Crucitti¹, Valentina Bessi¹, Sandro Sorbi^1,2, Benedetta Nacmias^1,2

1: Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; 2: IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy

Stable non-cohabiting relationships (Living Apart Together) and male sexual health: results from the EMAS population

Clotilde Sparano¹, Giammarco Alderotti², Giovanni Corona³, Giulia Rastrelli⁴, Linda Vignozzi⁴, Daniele Vignoli², Mario Maggi¹, EMAS group⁵

1: SODc Endocrinologia, Dipartimento di Scienze Biomediche, Sperimentali e Cliniche “Mario Serio”, Università degli Studi di Firenze, Firenze, Italia; 2: Department of Statistics, Computer Science, Applications, University of Florence, Florence, Italy; 3: Endocrinology Unit, Azienda USL Bologna, Bologna, Italy; 4: Andrology, Women’s Endocrinology and Gender Incongruence Unit, "Mario Serio", Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy; 5: EMAS group

Fertility intentions of migrants in Italy: searching for sources of variation between men and women and across origins

THAIS GARCIA PEREIRO¹, GIUSEPPE GABRIELLI², ANNA PATERNO¹, SALVATORE STROZZA²

1: Università degli Studi di Bari Aldo Moro; 2: Università degli Studi di Napoli Federico II

The Impact of Spousal Loss on Life Satisfaction: Evidence from SHARE.

Lucia Zanotto, Chiara Ludovica Comolli, Roberto Impicciatore

University of Bologna, Italy

Re-partnering in mid- and later life in Italy

Revathi Palat Rao¹, Elena Pirani²

1: University of Florence, Italy, Italy; 2: University of Florence, Italy, Italy

Health and Union Dissolution After Midlife: A Dyadic Approach

Giammarco Alderotti, Daniele Vignoli, Carlos Gil

University of Florence, Italy

Pronatalist vs. Structural Approaches to Addressing Low Fertility: Lessons from the Italian Case

Raffaele Guetto, Daniele Vignoli

University of Florence, Italy

The Contribution of Medically Assisted Reproduction to Fertility in Italy

Alessandra Burgio¹, Cinzia Castagnaro¹, Gustavo De Santis², Daniele Vignoli², Agnese Vitali³

1: Istat, Italy; 2: University of Florence, Italy; 3: University of Trento, Italy

Women reproductive health in ageing society and private pubblic intervention

Sara Landini, Simona Viciani, Giulia Biagioni, Emilia Giusti

Unifi, Italy

The meaning of Ageing: Perspectives from Ageing Migrants Caregivers in Italy

Lucrezia Alice Moschetta

Università di Padova, Italy

Supporting unpaid carers of older people in Italy: an analysis of the implementation of international policy recommendations at regional level

Giovanni Lamura, Cristina Calvi, Georgia Casanova, Federico Sofritti

INRCA IRCCS, Italy

Home Caregivers and Intersectional Discrimination: The Dark Side of the Care Sector

Maria Teresa Ambrosio, Luisa Corazza

Università degli Studi del Molise, Italy

Living (and Caring) Longer? Changes in Informal Care Provision Across Life in Italy

Cecilia Tomassini¹, Elisa Cisotto², Eleonora Meli³

1: Department of Economics, University of Molise, Italy; 2: Department of Statistics, Università Cattolica del Sacro Cuore, Milan, Italy; 3: ISTAT- Italian National Institute of Statistics, Italy

Feasibility and acceptability of Wearable Sensors and Online Questionnaires in Family Caregivers of People with Dementia: Preliminary Evidence from the ICare.IT – AvereCura Study

Ylenia Druda¹, Angela Berardi¹, Paola Di Florio¹, Marcello Sicbaldi¹, Francesco Palmese¹, M. Gabriella Melchiorre², Marco Socci², Serena Cancellieri², Mascia Tacconi³, Jessica Babini³, Francesca Zanasi¹, Eva Bei¹, Ilaria Chirico¹, Sara Trolese¹, Emma Capulli¹, Francesca Ingravallo¹, Rabih Chattat¹, Marco Albertini¹, Alessandro Silvani¹, Marco Domenicali¹

1: Università di Bologna - Alma Mater Studiorum, Italy; 2: National Institute of Health and Science on Ageing (INRCA), Italy; 3: Center for Cognitive Disorders and Dementias, Ausl Romagna, Italy

La figura del caregiver e la tutela della persona anziana. Questioni giuridiche trasversali

Stefano Corso, Arianna Fusaro, Giovanni Calabrese, Michela Lucchiari, Matilde Girolami, Mariassunta Piccinni

Università degli studi di Padova, Italy

Population ageing in Italy: household dynamics, care needs and labour participation

Fabrizio Culotta

University of Milan-Bicocca, Italy

Age-It Scholar: A Free Knowledge Hub on Ageing and Society

Mario Mezzanzanica

University of Milano - Bicocca

GDPR compliance and the use of microdata in AGE-IT research- Challenges and Possible Solutions

Matteo De Pamphilis¹, Giovanna Boccuzzo²

1: Ca' Foscari University Venice; 2: University of Padova, Italy

The new data sets created in Age-It: results from an online Survey

Agar Brugiavini

Ca' Foscari University of Venice, Italy

Metabolic profiling of MASLD patients identifies age-dependent and age-independent metabolic markers of liver fibrosis.

Tania D'Amico¹, Simone Giannini¹, Simone Di Cola¹, Annamaria Sabetta¹, Francesca Maiorca¹, Marin Pecani¹, Marzia Miglionico², Giulio Francesco Romiti¹, Serena Zampieri³, Greta Petrella³, Daniel Oscar Cicero³, Stefania Basili¹, Valeria Raparelli¹

1: Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; 2: Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy; 3: Department of Chemical Science and Technology, University of Rome "Tor Vergata," Rome, Italy

MAPK15 controls intracellular lipid uptake and protects mammalian liver from steatotic disease

Giovanni Inzalaco^1,2, Sara Gargiulo¹, Denise Bonente³, Lisa Gherardini¹, Lorenzo Franci^1,2, Federico Galvagni⁴, Virginia Barone³, Mario Chiariello^1,2

1: Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Siena, Italy; 2: Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica, Siena, Italy; 3: Department of Life Sciences, University of Siena University, Italy; 4: Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy

Linking Mitochondrial DNA Damage to Vascular Aging and Premature Coronary Artery Disease: Evidence from Clinical and Cellular Models

Paola Canale^1,3, Jonica Campolo², Lisa Alibrandi¹, Alessia Cuccaro¹, Francesca Scebba¹, Francesca Forini³, Giuseppina Nicolini³, Marina Parolini², Gianluca Gazzaniga⁴, Emanuela Piccaluga⁵, Irene Marinaro³, Antonella Mercuri³, Stefano Turchi³, Maria Grazia Andreassi³

1: Health Science Interdisciplinary Center, Sant'Anna School of Advanced Studies, Pisa, Italy; 2: CNR Institute of Clinical Physiology, Milan, Italy; 3: CNR Institute of Clinical Physiology, Pisa, Italy; 4: Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Rome, Roma, Italy; 5: Interventional Cardiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

Trace Metal Imbalance and Anemia Prevalence in Older Adults with Impaired Kidney Function: Evidence from NHANES

Guido Gembillo¹, Luca Soraci², Andrea Corsonello², Domenico Santoro¹

1: Unit of Nephrology and Dialysis, University of Messina, Italy.; 2: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), 87100 Cosenza, Italy.

Translating Science into Impact: Tackling Biological Ageing Through Innovation

Sofia Pavanello¹, Manuela Campisi², Luana Cannellla³

1: AZIENDA OSPEDALE UNIVERSITA' DI PADOVA, Italy; 2: AZIENDA OSPEDALE UNIVERSITA' DI PADOVA, Italy; 3: AZIENDA OSPEDALE UNIVERSITA' DI PADOVA. Italy

GDF-15, FGF21, sRAGE, and NfL as Biomarkers of Sarcopenia, Malnutrition, and Frailty: Evidence from the Age-It Study

Sarah Damanti^1,2, Clara Sciorati¹, Laura Zagato⁷, Lorena Citterio⁷, Edoardo Spinelli^1,3,4, Federica Agosta^1,3,4, Massimo Filippi^1,3,4,5,6, Paolo Manunta^1,7, Chiara Lanzani^1,7, Patrizia Rovere-Querini^1,2

1: Università Vita Salute San Raffaele, Italy; 2: Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 3: Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; 4: Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 5: Neurophysiology Service, IRCCS San Raffaele Scientific Institute, Milan, Italy; 6: Neurorehabilitation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 7: Nephrologic Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Searching for (dis-)similarities between the timing of international migration, union formation and acquisition of the Italian citizenship

Anna Paterno¹, Thaís García-Pereiro¹, Laura Terzera²

1: Università degli Studi di Bari Aldo Moro; 2: Università degli Studi di Milano-Bicocca

The Integration Paths of Eastern European Women in Italy: New Arrivals, Marriages, and Acquisitions of Citizenship

Cinzia Conti¹, Antonella Guarneri¹, Fabio Massimo Rottino¹, Salvatore Strozza²

1: Istat, Italy; 2: Università degli Studi di Napoli Federico II

Migrants' Socio-Economic Integration: The Case of Italy - Preliminary analysis

Roberta Defazio^1,2, Thaís García - Pereiro², Anna Paterno²

1: Università di Firenze & Università degli studi di Bari, Italy; 2: Università degli studi di Bari, Italy

Beyond Labour Integration: Migrant Women and Citizenship in an Ageing Italy

Rosa Gatti

Università degli Studi di Napoli Federico II, Italy

Assessing the Redistributive Aspects of the Italian Pension System

Koray Aktas, Danilo Cavapozzi, Monica Paiella

Ca' Foscari University of Venice, Italy

Measuring pension fragility

Koray Aktas¹, Danilo Cavapozzi¹, Monica Paiella²

1: Ca' Foscari University of Venice, Italy; 2: University of Naples "Parthenope", INPS

Occupation-specific health hazards and trajectories to retirement

Danilo Cavapozzi, Ya Gao, Irene Mammi

Ca' Foscari University of Venice, Italy

The implicit pension debt in pay-as-you-go pension systems: the stationary and balanced case

Gustavo De Santis

University of Firenze, Italy

Age-related trends of serum Neurofilament light chain in hospitalized and home-dwelling cohorts and prognostic relevance for mortality

Giulia Matacchione¹, Francesca Marchegiani¹, Francesco Piacenza², Mirko Di Rosa³, Matilde Sbriscia², Chiara Giordano¹, Sonia Fantone², Rina Recchioni¹, Nicola Montano⁴, Evelyn Ferri⁵, Stefano Salvioli^6,10, Maria Conte⁶, Beatrice Arosio^4,5, Antonio Domenico Procopio¹, Anna Rita Bonfigli⁷, Jacopo Sabbatinelli^1,9, Antonio Cherubini^8,9, Fabrizia Lattanzio⁷, Fabiola Olivieri^2,9

1: Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy; 2: Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; 3: . Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 4: Department of Clinical Sciences and Community Health, University of Milan, Miano,Italy; 5: Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico,Milano,Italy; 6: Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; 7: Scientific Direction, IRCCS INRCA, Ancona, Italy; 8: Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy; 9: . Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; 10: IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy

Detecting amyloid and tau pathology in Parkinson disease, 4R-tauopathies and control subjects with plasma ptau217

Eleonora Fiorenzato¹, Giulia Musso², Valentina Misenti¹, Simone Cauzzo¹, Roberta Biundo^3,4, Carmelo Fogliano¹, Giulia Bonato^1,5, Wassilios G. Meissner^6,7, Marta Campagnolo¹, Miryam Carecchio¹, Francesca Vianello³, Andrea Guerra¹, Chiara Cosma², Annachiara Cagnin^5,8, Diego Cecchin^5,9, Martina Montagnana², Angelo Antonini^1,5

1: Parkinson and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE), Department of Neuroscience, University of Padova, via Giustiniani 2, 35121 Padua, Italy; 2: Department of Medicine – DIMED, University of Padova, via Giustiniani 2, 35121 Padua, Italy; 3: Complex Operative Unit (UOC) of the Psychology, Neurology Hospital division, Padova University Hospital, via Giustiniani 2, 35121 Padua, Italy; 4: Department of General Psychology, University of Padova, via Venezia 8, 35131 Padua, Italy; 5: Padova Neuroscience Center (PNC), University of Padova, via Orus 2b, 35131 Padua, Italy; 6: CHU Bordeaux, Service de Neurologie des Maladies Neurodégénératives, IMNc, Place Amélie Raba-Léon, 33000 Bordeaux, France; 7: Univ. de Bordeaux, CNRS, IMN, UMR 5293, 146 rue Léo Saignat, 33000 Bordeaux, France; 8: Department of Neuroscience, University of Padova, via Giustiniani 2, 35121 Padua, Italy; 9: Nuclear Medicine Unit, Department of Medicine (DIMED), University of Padova, via Giustiniani 2, 35121 Padua, Italy

Innovating Brain Health: An Italian Experience with a Community-Based Service

Edoardo Gioele Spinelli^1,2, Elisa Canu², Elisa Sibilla², Bianca Lamorgese¹, Giordano Cecchetti², Veronica Castelnovo², Giulia Rugarli^1,2, Alma Ghirelli^1,2, Roberto Santangelo², Jacopo Lanzone², Marco Cursi², Luca Zanchi², Federica Agosta^1,2, Massimo Filippi^1,2

1: Vita-Salute San Raffaele University, Italy; 2: IRCCS Ospedale San Raffaele

Shp1 Modulates Apoptosis and Senescence Pathways in Retinal Cells: Implications for Age-Related Macular Degeneration

Sabrina Gargiulo, Antonino Colanzi, Daniela Corda, Alessia Varone

Institute of Endotypes in Oncology, Metabolism, and Immunology “G. Salvatore”, National Research Council, Naples, Italy

The Cost of Loss: Unequal Bereavement effects in Later Life

Chiara Ludovica Comolli¹, Diego Pieroni², Valentina Ricci²

1: Università di Bologna, Italy; 2: INPS

New insights into fertility intentions and realizations through a longitudinal register of individuals in Italy

Cinzia Castagnaro¹, Eleonora Meli¹, Daniele Vignoli², Letizia Mencarini³

1: Istat, Italy; 2: University of Florence; 3: Bocconi University

Work-family trajectories and health: the role of partners’ crossover effects

Davide Gritti, Raffaele Grotti, Stefani Scherer

Trento University, Italy

Income and Fertility in Couples: New Evidence from Longitudinal Tax Data in Tuscany

Carlos J. Gil-Hernández¹, Daniele Vignoli¹, Raffaele Guetto¹, Marialuisa Maitino², Letizia Ravagli²

1: University of Florence, Department of Statistics, Computer Science, Applications, Italy; 2: Istituto Regionale per la Programmazione Economica della Toscana (IRPET), Italy

Modern Family: Transition to Single Parenthood and the Consequences for Well-Being

Andrea Ballerini, Raffaele Guetto

University of Florence, Italy

Attitudes towards ART: a vignette study

Daniele Vignoli¹, Valentina Tocchioni², Marco Cozzani³, Ester Lazzari⁴

1: Università degli Studi di Firenze, Italy; 2: Università degli Studi di Firenze, Italy; 3: Università degli Studi di Firenze, Italy; 4: Vienna Institute of Demography

Silver surfers' social ties: understanding social network usage among Italian seniors

Margherita Silan, Giorgia Bernardinis, Sophie Grace Parolin

University of Padova, Italy

Older LGBTQ+ Adults and Affirmative Sports Environments: Indicators and Best Practices

Chiara Antoniucci¹, Roberto Baiocco¹, Jessica Pistella¹, Guido Alessandri², Fabio Alivernini¹, Anna Maria Borghi³, Andrea Chirico¹, James Dawe⁴, Lorenzo Filosa², Chiara Fini³, Tommaso Palombi³, Simone Tavolucci², Fabio Lucidi¹

1: Department of Social and Developmental Psychology, Sapienza University of Rome, Italy; 2: 2 Department of Psychology, Sapienza University of Rome, Italy; 3: Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Italy; 4: Department of Humanities and Social Sciences, Universitas Mercatorum Telematic University, Italy

Matching care needs of LGBTQAI+ older adults and care workers’ education: a systematic review of reviews

Rebecca Graziosi, Georgia Casanova, Giovanni Lamura

INRCA, Italy

Improving Elderly Quality of Life through Innovative Social Day Care Centres. A Case Study in Rome within the Age-It Programme

Maria Argenti, Fabio Cutroni, Domizia Mandolesi, Anna Bruna Menghini, Maura Percoco, Francesca Sarno

Sapienza University of Rome, Italy

Sex-specific network dynamics of multimorbidity

Erika Banzato, Giovanna Boccuzzo

Department of Statistical Sciences, University of Padova, Padova, Italy

Forgotten in the hospital: The Effect of Municipality Social Spending on Elderly Hospital-related Outcomes.

Giovanni Fattore, Simone Ghislandi, Irene Torrini

Department of Social and Political Sciences, Bocconi University, Italy

PrivGen: A Human-in-the-Loop Approach to Generate Private Synthetic Data

Navid Nobani¹, Giovanni Officioso¹, Mario Mezzanzanica¹, Giancarlo Sperlì², Fabio Mercorio¹

1: University of Milan-Bicocca, Italy; 2: University of Naples Federico II, Naples, Italy

A Thematic Data Platform for Research on Ageing

Mario Mezzanzanica, Fabio Mercorio, Navid Nobani, Anna Velyka, Filippo Pallucchini

University of Milan-Bicocca, Italy

Bridging Data for Better Ageing: Advancing Measurement of Healthy Ageing in Italy

Andreea Alexandra Piriu, Aleksandra Torbica

Bocconi University, Italy

Development of a Parallel, Multi-Wavelength, Multi-Channel, Multi-Distance, Time-Resolved Near Infrared Spectrometer

Scott Pesenti¹, Alessandro Torricelli^1,2, Lorenzo Spinelli¹

1: Consiglio Nazionale delle Ricerche, Italy; 2: Dipartimento di Fisica, Politecnico di Milano

Experimental analysis and physics-based analytical model on Twisted and Coiled Artificial Muscles (TCAMs): innovative smart actuators for rehabilitation robotics

Salvatore Garofalo, Chiara Morano, Leonardo Pagnotta, Luigi Bruno

Department of Mechanical, Energy and Management Engineering, University of Calabria, Rende, Italy

COG-BCI: an adaptive EEG-based Brain Computer Interface for COGnitive training in elderly people

Emma Colamarino^1,2, Elena Mongiardini¹, Febo Cincotti^1,2

1: Sapienza University of Rome, Italy; 2: Fondazione Santa Lucia IRCCS, Rome, Italy

Biomechanical Assessment of Exo-Assistance

Raffaella Mancino¹, Aldo Smaldone², Mariarosaria Meola², Raffaele Dubbioso², Giovanni Berselli¹, Fanny Ficuciello²

1: Università di Genova, Italy; 2: Università degli studi di Napoli Federico II

On the development of a novel Virtual Sensing methodology for indirect sensing of muscle forces during robotic rehabilitation and motion assistance

Michele Perrelli, Rocco Adduci, Francesca Alvaro, Domenico Mundo

University of Calabria, Italy - Department of Mechanical, Energy, and Management Engineering

VITAL SIGNAL MEASUREMENTS AND FEATURES EXTRACTIONS FROM A LOW-COST DEVICE IN AGEING

Livio D'Alvia¹, Chiara Bencivenga¹, Roberto Cangemi², Stefania Basili², Zaccaria Del Prete¹

1: DIMA, Sapienza University of Rome, Via Eudossiana 18 – 00100, Rome; 2: DMTP, Sapienza University of Rome, Viale del Policlinico, 155 - 00185 - Roma

Territorial Disparities and School Dropouts in Italian High Schools

Salvatore Battaglia, Naomi Failla, Umberto De Simone, Massimo Attanasio

University of Palermo, Italy

Neurophysiological markers of human-exoskeleton integration

Margherita Bertuccelli^1,2, Stefano Tortora^1,2, Mariasole Pasinato¹, Edoardo Trombin¹, Alfonc Baba^2,3, Patrizia Bisiacchi⁴, Giovanni Sparacino¹, Emanuele Menegratti^1,2, Alessandra Del Felice^2,3

1: Department of Information Engineering, Università degli studi di Padova, Italy; 2: Padova Neuroscience Center, Università degli studi di Padova; 3: Department of Neuroscience, Università degli studi di Padova; 4: Department of General Psychology, Università degli studi di Padova

Novel biomarkers for the diagnosis of cognitive decline in patients with chronic kidney disease

Maria Teresa Cimmarusti, Alessandra Stasi, Marco Fiorentino, Rossana Franzin, Monica Campioni, Sabrina Carparelli, Paola Pontrelli, Loreto Gesualdo

University of Bari, Italy

Polypharmacy and Orthostatic Hypotension in Hospitalized Older Patients: A Cross-Sectional Analysis

Laura Andreea Ceparano, Laura de Lisio, Chiara Di Lorenzo, Alessandro Caracciolo, Giovanni Curcio, Lucia De Maria, Gambino Giuseppina, Maria Grazia Landi, Pasquale Pezzella, Ivana Serino, Annachiara Vassallo, Valeria Zanobbi, Grazia Daniela Femminella, Nicola Ferrara, Giuseppe Rengo, Leonardo Bencivenga

Dipartimento di Scienze Mediche Traslazionali, Federico II University, Naples, Italy, Italy

The Role of Cardiopulmonary Exercise Testing in the Evaluation of Patients with Anderson-Fabry Disease

Alessandra Cuomo, Antonio Bianco, Antonella Di Donato, Letizia Spinelli, Eleonora Riccio, Maddalena Illario, Antonio Pisani, Guido Iaccarino

Università degli Studi di Napoli Federico II, Italy

“Ageing? I say yes!”: a Hybrid-AI Approach to develop a web application for sustaining older workers’ work-life balance.

Greta Falavigna¹, Donatella Bramanti², Luisa Errichiello³, Sara Nanelli⁴

1: Research Institute on Sustainable Economic Growth of the National Research Council (CNR-IRCrES)), Italy; 2: Università Cattolica del Sacro Cuore di Milano; 3: Institute for Studies on the Mediterranean of the National Research Council (CNR-ISMed)), Italy; 4: Università Cattolica del Sacro Cuore di Milano

Age-related acidosis as a driver of bone marrow adipose tissue changes in osteoporosis

Jasmine Molaschi¹, Gemma Di Pompo², Sofia Avnet¹, Nicola Baldini^1,2

1: Università degli Studi di Bologna, Italy; 2: IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Aging lung: the association between muscle strength and z scores of pulmonary function in a general population sample

Nicola Ferrara¹, Laura Petraglia¹, Leonardo Bencivenga¹, Giuseppe Rengo¹, Raffaella Pagliaro², Angela Sciattarella², Andrea Bianco², Germano Guerra³, Klara Komici³

1: University of Naples "Federico II", Italy; 2: University of Campania "L. Vanvitelli," Naples, Italy.; 3: University of Molise, Campobasso, Italy

Cognitive performance and gait analysis in cognitively unimpaired adults. Preliminary findings from the “Instrumental Pattern of Cognitive Decline: a data-driven approach. The DataCOG Study”.

Federico Mollame¹, Alice Tomaselli¹, Andrea Caruso², Massimiliano Salfi², Caterina Gagliano¹, Francesco Cappellani¹, Antonino Maniaci¹, Emilia Gallo¹, Francesco Pegreffi¹, Salvatore Lavalle¹, Roberta Torrisi², Antonina Luca¹

1: University of Enna Kore, Italy; 2: vEyes ONLUS

Customizable Hybrid Exo-Prosthesis System

Marcella Piacentino, Mariarosaria Meola, Fanny Ficuciello

Università degli Studi di Napoli 'Federico II', Italy

Demographic dynamics and the labor market

Valeria Allocca

Università degli Studi di Napoli Federico II, Italy

Demographic trends and investment strategies: How longevity shapes pension funds' equity exposure

Rosa Cocozza, Domenico Curcio, Serena Gallo

University of Naples Federico II, Italy

Development and Validation of Shape Memory Alloy-Based Actuators for Rehabilitative Exoskeletons

Stefano Rodinò¹, Carmine Maletta²

1: UNICAL, Italy; 2: 2SMArtest

Diritto del lavoro e persona anziana: il c.d. Age Management nel contesto aziendale

Michela Lucchiari, Arianna Fusaro, Giovanni Calabrese, Stefano Corso, Mariassunta Piccinni, Matilde Girolami

Università degli Studi di Padova, Italy

Impaired cAMP/PKA/CREB1 signaling drives mitochondrial dysfunction in skeletal muscle wasting

Elia Angelino^1,2, Lorenza Bodo², Suvham Barua^1,2, beatrice D'Anna², Alessia Meschi², Carolina Sciavolino², Andrea Graziani^1,2

1: Università del Piemonte Orientale, Dept. of Translational Medicine, Italy; 2: Università di Torino, Molecular Biotechnology Center, Department of Molecular Biotechnology and Healths Sciences

Irisin correlates with disease biomarkers and cognitive function in Alzheimer disease.

Manuela Dicarlo¹, Patrizia Pignataro², Daniele Urso³, Chiara Zecca³, Roberta Zerlotin¹, Graziana Colaianni¹, Angela Oranger¹, Clelia Suriano², Silvia Colucci², Giancarlo Logroscino³, Maria Grano¹

1: University of Bari "Aldo Moro",Department of Precision and Regenerative Medicine and Ionian Area,Italy; 2: University of Bari "Aldo Moro", Department of Translational Biomedicine and Neuroscience, Italy; 3: Center for Neurodegenerative Diseases and the Aging Brain, University of Bari “A. Moro” at “Pia Fondazione Card G. Panico” Hospital, Italy.

Loneliness in caregivers of patients with cognitive decline

Rita Pezzella, Chiara De Salvo, Gianluca Scotto di Tella, Vittoria Canzanella, Maddalena Vasto, Sara Rinaldi Landolina, Carmine Dello Russo, Maria Perrotti, Luca Corbia, Valeria Accardo, Dario Leosco, Giuseppe Rengo, Laura Petraglia, Grazia Daniela Femminella

University of Naples Federico II, Italy

Low-grade inflammation, platelet reactivity and mitochondrial function in individuals with permanent atrial fibrillation.

Francesco Vollero, Giovanni Buoninfante, Valeria Trapani, Angela Pia Speziale, Annamaria Sabetta, Francesca Maiorca, Valeria Raparelli, Stefania Basili, Giulio Francesco Romiti, Lucia Stefanini

Department of Translational and Precision Medicine, Sapienza University of Rome, Italy.

Multimodal Instrumentation for Thermodynamic Data Collection and Validation in Aerobic Exercise across age-spectrum Through Infrared Thermography

Aiman Rashid, Assal Selma, Matteo Cammarata, Daniele Fiaschi

Università degli Studi di Firenze, Italy

National Recovery and Resilience Plan (NRRP) Cascade Funding - Age-it. CODIGE Project: Comorbidity and Iatrogenic Damage in Geriatric Oncology. Objectives, Methodologies, Study population and Expected results

Amelia Filippelli¹, Anna Citarella², Simona Cammarota², Federica Papaccio¹, Elena Ciaglia¹, Federica Campana¹, Emanuela De Bellis¹, Nicola Ferrara³, Valeria Conti¹

1: Department of Medicine Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Baronissi, Italy; 2: LinkHealth - Health economics, Outcomes & Epidemiology srl, Naples, Italy; 3: Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.

Nutritional Status and Sympathovagal Imbalance in Elderly Patients

Maria Perrotti, Mariapia Calligari, Martina Valentino, Luca Corbia, Carmine Dello Russo, Stefano Maisto, Dario Leosco, Giuseppe Rengo, Grazia Daniela Femminella, Laura Petraglia

Department of Translational Medical Science, University of Naples “Federico II”

Outcome measures for health interventions targeting multimorbid older adults: A systematic review.

Massimiliano Fedecostante¹, Alessia Beccacece¹, Paolo Balietti¹, Barbara Carrieri¹, Massimiliano Orso¹, Alessandra Coin², Chiara Ceolin², Giuseppe Sergi², Francesca Cecchi³, Marco Baccini³, Diego Longo³, Rosa Liperoti^4,5, Fabrizia Lattanzio¹, Antonio Cherubini¹

1: IRCCS INRCA, Ancona, Italy; 2: University of Padua, Padua, Italy; 3: University of Florence, Florence, Italy; 4: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; 5: Università Cattolica del Sacro Cuore, Milan, Italy.

Recognize the talent. Complexity of the transmission of "know-how" between generations in the Veneto craftsmanship

Fabio Gasparini

Consiglio Nazionale Ricerche (IRPPS), Italy

Reducing vulnerability to online misinformation among older adults: a literature review

Cristina Meini¹, Erica Viola², Caristia Silvia³

1: University of Eastern Piedmont, Italy; 2: University of Eastern Piedmont, Italy; 3: University of Eastern Piedmont, Italy

SGLT2 inhibitors and cognitive decline: a systematic review and meta-analysis

Chiara Di Lorenzo¹, Laura Andrea Ceparano¹, Laura de Lisio¹, Grazia Daniela Femminella¹, Nicola Ferrara¹, Leonardo Bencivenga¹, Klara Komici², Giuseppe Rengo¹

1: Università degli Studi di Napoli Federico II, Italy; 2: Università degli Studi del Molise, Italy

The Role of Regular Physical Activity in Restoring Immune Balance After Myocardial Infarction in Older Adults

Davide Proietto, Elena Torreggiani, Antonella Caputo, Riccardo Gavioli, Simona Mandini, Elisabetta Tonet, Beatrice Dallan, Enrico Tassani, Mara Martino, Tommaso Piva, Valentina Zerbini, Andrea Raisi, Gianluca Campo, Giovanni Grazzi, Francesco Nicoli

University of Ferrara, Italy

The Role of Rehabilitation in Preventing Falls in the Elderly: Presentation of the Pilot Study

ANTONIO PICONE, PALOMBA ANGELA, LEMMO DANIELA, MEZZA FABRIZIO, FREDA FRANCESCA, RUOSI CARLO

University of Naples Federico II, 80131 Naples, Italy, Italy

Total factor productivity and health for ageing workers in the Italian regions

Emanuela Resta

University Sapienza of Rome, Italy

Unravelling the link between uromodulin dosage, aging and risk of chronic kidney disease

Sofia Bindelli¹, Mariapia Giuditta Cratere¹, Claudia Tammaro¹, Lara Davani², Alessandra Altomare², Céline Schaeffer¹, Luca Rampoldi¹

1: Molecular Genetics of Renal Disorders, Division of Genetics and Cell Biology, University Vita-Salute San Raffaele, Milan; 2: Department of Pharmaceutical Analysis, University of Milan

Re-Starting! How women over 50 learn to teach?

Anna D'Ascenzio

CNR, Italy

From migration to familiarisation. Family profiles, family-making processes and policy challenges in Italy

Stefano Montrasio, Laura Terzera

Università degli Studi di Milano-Bicocca, Italy

Radiomics and Machine Learning for Breast Density Classification in elderly patients from MRI

Corrado Caiazzo, Francesco Mercaldo, Giulia Varriano, Dalila De Lucia, Maria Chiara Brunese, Simona Correra, Antonella Santone

Università degli Studi del Molise, Italy

Replacement Migration: Respect and Harms

Davide Pala¹, Gloria Zuccarelli²

1: Università Piemonte Orientale, Italy; 2: Università Piemonte Orientale, Italy

Active waiting spaces in primary care territorial facilities to promote healthy ageing

Elena Bellini, Nicoletta Setola

University of Florence, Department of Architecture, TESIS center, Italy

Beyond the Skin: Integrating mHealth and Multidisciplinary Care in Hidradenitis Suppurativa Management

Annachiara Cavaliere

Università degli Studi di Napoli Federico II, Italy

Innovative intervention supported by digital technologies for healthy and active ageing: Innovative approach to the subject with hypogonadism.

Francesco Garifalos, Davide Menafra, Cristina de Angelis, Angelica Larocca, Michele Virgolesi, Sara Aprano, Vincenzo De Luca, Erminia Attaianese, Mariangela Perillo, Daniela Lemmo, Maria Francesca Freda, Guido Iaccarino, Maddalena Illario, Annamari Colao, Rosario Pivonello

Università degli Studi di Napoli Federico II, Italy

Role Of Mitochondrial Dysfunction In The Pathogenesis Of Fabry Cadriomiopathy

Jessica Gambardella, Antonella Fiordelisi, Federica Andrea Cerasuolo, Antonietta Buonaiuto, Roberta Avvisato, Alessandra Cuomo, Antonio Bianco, Eleonora Riccio, Antonio Pisani, Daniela Sorriento, Guido Iaccarino

Università degli Studi di Napoli Federico II, Italy

The Role of Nursing in Promoting Health for Aging Populations: A scoping review

Michele Virgolesi

Università Federico II di Napoli, Italy

Trapped by Age and Gender: Exploring the Combined Effects of Ageism and Sexism in Organizational Settings

Alessia Valmori, Claudia Manzi

Catholic University of the Sacred Heart - Milan, Italy

Brief online vocal interactions influence closeness and sensorimotor-interoceptive activation in an age-dependent manner

Chiara Fini, Vanessa Era, Giovanna Cuomo, Ilenia Falcinelli, Anna M, Borghi

Sapienza, University of Rome, Italy

Thinking Climate Change through the Lens of Abstractness: A Multi-Task and Multi-Setting Investigation into Generational Differences in the Conceptualization of Ecology

Ilenia Falcinelli¹, Chiara Fini¹, Claudia Mazzuca¹, Ludovica Gargiuli¹, Guido Alessandri¹, Fabio Alivernini¹, Roberto Baiocco¹, Andrea Chirico¹, Lorenzo Filosa¹, Tommaso Palombi¹, Jessica Pistella¹, Simone Tavolucci¹, Fabio Lucidi¹, Anna M. Borghi^1,2

1: Sapienza University of Rome, Italy; 2: ISTC-CNR, Rome

Combined Analysis of Alu and ALR Repeats in cfDNA: Potential Prognostic Biomarkers in Geriatric Patients with Cardiovascular Disease

Rosanna Maniscalco¹, Stefania Fumarola¹, Francesca Marchegiani², Emanuele Francini², Alessandro Petrini¹, Anna Rita Bonfigli³, Roberta Galeazzi², Jacopo Sabbatinelli^2,4, Antonio Domenico Procopio^2,4, Mirko Di Rosa⁵, Pierpalo Stripoli², Roberto Antonicelli⁶, Rina Recchioni², Antonio Cherubini^4,7, Fabrizia Lattanzio³, Fabiola Olivieri^1,4, Maurizio Cardelli¹

1: Advanced Technology Center for Aging Research, IRCCS INRCA, Ancona, Italy; 2: Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy; 3: Scientific Direction, IRCCS INRCA, Ancona, Italy; 4: Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; 5: Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 6: Cardiology Unit, IRCCS INRCA, 60129 Ancona, Italy; 7: Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona,

Cellular senescence in painful neuropathies: characterization of the senescent phenotype

Chiara Sasia, Giacomina Videtta, Nicoletta Galeotti

University of Florence, Italy

Voices from the Margins: A Poetic Inquiry into Women’s Ageing in Mountainous Territories

Francesca Romana Loberto

University of Milano-Bicocca, Italy

Becoming a Family and Community Nurse: navigating role identity in a fragmented system. A phenomenological study

Isabella Santomauro¹, Erika Bassi¹, Erica Busca¹, Ines Basso¹, Elisa Ambrosi², Melania Stedile², Angela Durante^3,4, Alberto Dal Molin¹

1: Department of Translational Medicine, University of Piemonte Orientale, Italy; 2: Department of Diagnostics and Public Health, University of Verona, Italy; 3: Tuscany Foundation “G. Monasterio", Italy; 4: Health Science Interdisciplinary Center, Scuola Superiore Sant’Anna, Italy

Communicating Complex Statistical Models to a Public Health Audience: Translating Science into Action with the FARSI Approach.

Mattia Stival, Lorenzo Schiavon, Gaia Bertarelli, Stefano Campostrini

Ca' Foscari University of Venice, Italy

Mutuality in the relationship between Family and Community Nurses and the Patient-Caregiver Dyad

Erica Busca¹, Erika Bassi^1,2, Alberto Dal Molin^1,2

1: University of Piemonte Orientale, Italy; 2: Maggiore della Carità University Hospital, Italy

BENE: Brain Exercise and Nutrition in Elderly population

Gioi Spinello, Tatiana Moro, Antonio Paoli

University of Padua, Italy

Personality traits, biochemical markers, and cognitive function: a preliminary analysis from the Novara Cohort Study

Giulia Garro^1,2, Marco Martorana⁵, Silvia Vittoria Cracas^2,3, Jacopo Venetucci^1,2, Vittoria Colombo¹, Lucrezia Capuzzi¹, Davide Rossato², Luca Briacca^1,2, Annamaria Antona¹, Marco Varalda^1,2, Erica Viola¹, Roberta Rolla⁴, Fabrizio Faggiano³, Daniela Capello^1,2

1: Department of Translational medicine, University of Piemonte Orientale, Novara, Italy; 2: UPO Biobank, University of Piemonte Orientale, Novara, Italy; 3: Department of Sustainable Development and Ecologic Transition, University of Piemonte Orientale, Vercelli, Italy; 4: Clinical Chemistry Laboratory, Department of Health Sciences, University of Piemonte Orientale, Maggiore della Carità University Hospital, Novara, Italy; 5: University of Florence, Firenze, Italy

The GREAT Project: a biobank collection of adipose-derived mesenchymal stem cells and patient-derived tumor organoids to advance research in aging, cancer, and personalized therapy

Annamaria Antona¹, Roberto Angiono^1,2, Giulia Garro^1,3, Jacopo Venetucci^1,3, Marco Varalda^1,3, Silvia Cracas^1,3,4, Agnese Volpicelli^1,5, Arefeh Hashemizadeh¹, Chaitanya Reddy Kankara¹, Valentina Bettio³, Renzo Boldorini^6,7, Sergio Gentilli^1,7,8, Daniela Surico^1,5, Guido Valente^1,2, Daniela Capello^1,3

1: Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 2: Pathology Unit, Ospedale Sant'Andrea, Vercelli, Italy; 3: UPO BIOBANK, University of Piemonte Orientale, Novara, Italy; 4: Department of Sustainable Development and Ecologic Transition, University of Piemonte Orientale, Vercelli, Italy; 5: Gynecology Unit, AOU Maggiore della Carità, Novara, Italy; 6: Pathology Unit, AOU Maggiore della Carità, Novara, Italy; 7: Department of of Health Sciences, University of Piemonte Orientale, Novara, Italy; 8: General Surgery Division, AOU Maggiore della Carità, Novara, Italy

The combination of 4 age-related biomarkers, GDF15, FGF21, sRAGE and NfL, can identify frailty in older community-dwelling people

Maria Conte¹, Federica Sevini¹, Giuseppe Conte², Lorenzo Trofarello¹, Antonio Chiariello¹, Miriam Capri¹, Claudio Franceschi³, Daniela Monti⁴, Mirko Di Rosa⁵, Antonio Cherubini^6,7, Fabiola Olivieri^5,7, Stefano Salvioli^1,8

1: University of Bologna, Italy; 2: University of Pisa, Italy; 3: Lobachevsky University, Russia; 4: University of Florence, Italy; 5: Italian National Research Center on Aging, IRCCS INRCA, Italy; 6: Geriatria, Accettazione geriatrica e Centro di ricerca per l’invecchiamento, IRCCS INRCA, Italy; 7: Università Politecnica Delle Marche, Italy; 8: IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy

Long-term exposure to air pollution in population-based studies: data quality, metrics, and associations with cardiovascular health. The RoCAV study

Giovanni Veronesi¹, Marco Mario Ferrario¹, Alessandro Gialluisi^2,3, Francesco Gianfagna¹

1: Research Center in Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Varese, Italy; 2: Department of Medicine and Surgery, LUM University, Casamassima, Italy; 3: Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy

Multi-domain Interventions to improve the COgnitive and fUNctional well-being of elderly individuals in residential sTructures: the I COUNT study - baseline evaluations

Zaira Romeo¹, Eleonora Macchia¹, Chiara Ceolin², Mario Virgilio Papa², Alvise Bobbo¹, Giacomo Scotti³, Giulia Pasolini³, Alessia Ghidini⁴, Maria Patrizia Arsie⁵, Arianna Sanasi⁵, Ilaria Bandera⁴, Monica Cadei⁴, Marta Cominetti⁴, Elisa Danieli⁴, Bianca Faraci⁴, Rosa Filippelli⁴, Silvia Frosi⁴, Emma Giovannini⁴, Maria Legierska⁴, Paolo Maggi⁴, Stefano Moscarella⁴, Sabina Perelli Ercolini⁴, Giulia Principato⁴, Daniela Radeanu⁴, Loretta Ruggeri⁴, Simona Gentile⁴, Alessandro Morandi^3,4, Stefania Maggi¹, Marianna Noale¹

1: Neuroscience Institute, National Research Council, Padua, Italy; 2: Geriatrics Unit, Department of Medicine (DIMED), University of Padua, Italy; 3: Department of clinical and experimental science, University of Brescia, Italy; 4: Azienda Speciale Cremona Solidale, Cremona, Italy; 5: Pensionato Piaggi, AltaVita IRA, Padua, Italy

Preliminary testing of a new computer-based platform for cognitive stimulation and use in the context of the “Multidomain Interventions to improve the COgnitive and fUNctional well-being of elderly individuals in residential sTructures” (I-COUNT) pilot study

Eleonora Macchia¹, Zaira Romeo¹, Maria Devita^2,3, Maria Patrizia Arsie⁴, Arianna Sanasi⁴, Giacomo Scotti⁵, Giulia Pasolini⁵, Alessia Ghidini⁵, Giorgia Ghilardotti⁶, Elena Lucchi⁶, Alessandra Martelli⁶, Stefano Moscarella⁶, Lucia Tonani⁶, Francesca Dondé⁶, Maria Giovanna Pangallo⁶, Simona Gentile⁶, Alessandro Morandi^5,6, Stefania Maggi¹, Marianna Noale¹

1: Neuroscience Institute, National Research Council, Padua, Italy; 2: Geriatrics Unit, Department of Medicine (DIMED), University of Padua, Italy; 3: Department of General Psychology, University of Padua, Italy; 4: Pensionato Piaggi, Altavita IRA, Padua, Italy; 5: Department of clinical and experimental science, University of Brescia, Italy; 6: Azienda speciale Cremona Solidale, Cremona, Italy

From generation to implementation of evidence: a comparative analysis of 3 RCTs on active ageing in the Age-It Project

Erika Renzi¹, Valentina Baccolini¹, Giuseppe Migliara², Corrado De Vito¹, Carolina Marzuillo¹, Paolo Villari¹, Azzurra Massimi¹

1: Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy; 2: Department of Life Sciences, Health, and Health Professions, Link Campus University, Rome, Italy.

Optimizing prevention of hospital-acquired disability through integrated multidomain interventions: the OPTIMAge-IT trial

Maria Cristina Ferrara¹, Chukwuma Okoye¹, Alberto Finazzi¹, Beatrice Tonus¹, Wenxiang Guo¹, Eleonora Cucini¹, Anna Vanoncini¹, Greta Tavecchi¹, Paola Negri¹, Maria Chiara De Ponti¹, Fabio Guerini², Gianluca Bianco³, Alberto Zucchelli³, Alessandro Mengozzi⁴, Luca Soraci⁵, Elvira Clausi⁶, Lorella Lambertucci⁷, Carmen Ruberto⁸, Giovanni Ruotolo⁸, Filippo Fimognari⁶, Andrea Corsonello⁵, Agostino Virdis⁴, Andrea Ungar⁷, Alessandra Marengoni³, Giuseppe Bellelli¹

1: School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 2: Department of Medicine, S. Anna Hospital, Brescia, Italy; 3: Department of Clinical and Experimental Sciences, University of Brescia, Italy; 4: Department of Clinical and Experimental Medicine, University of Pisa, Italy; 5: Unit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy; 6: Unit of Geriatrics, Department of Internal Medicine, "Annunziata-Mariano Santo-S. Barbara" Hospital, Cosenza, Italy; 7: Department of Experimental Medicine and Clinical Medicine, University of Florence, Florence, Italy; 8: Geriatric Unit Center for Cognitive Disorders and Dementia, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy

Prevention interventions stratified by risk of Healthy Aging in older adults: A Systematic Review

Alberto Catalano^1,2, Winston Gilcrease², Federica Buscema², Savino Sciascia², Fulvio Ricceri²

1: University of Eastern Piedmont, Department of Translational Medicine, Novara, Italy; 2: University of Turin, Department of Clinical and Biological Sciences, Turin, Italy

Understanding Implementation of the Family and Community Nurse Role in Northern Italy: A Case Study

Erika Bassi^1,2, Erica Busca¹, Alberto Dal Molin^1,2

1: University of Piemonte Orientale, Italy; 2: Maggiore della Carità University Hospital, Italy

Explaining differential alignment in rural ageing: being on the track or sliding back?

FRANCESCA DONATI¹, TIZIANA NAZIO^1,2

1: Università del Piemonte Orientale, Italy; 2: Università di Torino

AGEITALY- A MULTI-PURPOSE STUDY ON ACTIONS, STRATEGIES AND POLICIES PROMOTING ACTIVE AND HEALTHY AGEING IN ALL ITALIAN POLICIES

Guido Giarelli, Marilin Mantineo, Olena Ignatenko, Nikolai Pagano, Ludovica Rossotti

UNIVERSITA' MAGNA GRAECIA, Italy

Active ageing policies in Italy: recent developments and future prospects

Davide Lucantoni, Andrea Principi

National Institute of Health and Science on Ageing (IRCCS-INRCA), Italy

Transitions in older age under the lens of active ageing: a scoping review

Marco Socci¹, Davide Lucantoni¹, Maria Vittoria Bufali², Andrea Principi¹

1: IRCCS INRCA - National Institute of Health and Science on Ageing, Ancona, Italy; 2: Bocconi University, Milan, Italy

Social participation and active ageing policies: from macro-context to individual responsibilities

CARMINE CLEMENTE

Università di Bari - Dipartimento FOR.PSI.COM., Italy

Designing for ageing well: development of design guidelines of gerontechnology to promote healthy and active ageing

Mattia Pistolesi, Iris Ayame Brunella Verzì, Francesca Tosi

University of Florence, Italy

Effects of pet ownership on physical performance in older outpatients: preliminary data from a pilot study

Greta Ceccarelli, Fiorella Aversano, Gilda Zondini, Ilaria Ambrosino, Ilenia Barbieri, Olimpia Martini, Arianna Tariello, Ludovica Ceolin, Giulia Spanalatte, Thierry Wenger, Giulia Rivasi, Enrico Mossello, Andrea Ungar

University of Florence and Division of Geriatric and high-intensity Care Medicine and Geriatric Cardiology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

Integration of clinical, biological and psycho-social variables for a gender-sensitive frailty prediction: study design

Valeria Trapani¹, Marzia Miglionico², Tania D'Amico¹, Angela Speziale¹, Elisa Tavano¹, Francesca Maiorca¹, Lucia Stefanini¹, Marcella Visentini¹, Roberto Cangemi¹, Marco Proietti^3,4, Giulio Francesco Romiti¹, Valeria Raparelli¹, Antonio Cherubini⁵, Pasquale Abete⁶, Stefania Basili¹

1: Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; 2: Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.; 3: Department of Clinical Sciences and Community Health, University of Milan, Italy; 4: Division of Cardiogeriatric Subacute Care, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy; 5: Geriatria, Accettazione Geriatrica e Centro di Ricerca Per l'invecchiamento, IRCCS INRCA, Ancona, Italy; 6: Department of Translational Medical Sciences (DISMET), Federico II University, Naples, Italy

Longitudinal Impact of Atrial Fibrillation on Physical Performance in Older Adults: The Role of Cognitive Function, Frailty, and Sex

Alessandra Coin^1,2, Chiara Ceolin^1,2, Eleonora Mizzon¹, Marianna Noale³, Adele Ravelli¹, Sabrina Pigozzo¹, Chiara Curreri², Bruno Micael Zanforlini², Maria Devita^1,4, Marina De Rui², Giuseppe Sergi^1,2

1: Department of Medicine (DIMED), University of Padua, Padua, Italy; 2: Division of Geriatrics, University Hospital of Padua, Padua, Italy; 3: National Research Council, Neuroscience Institute, Padua, Italy; 4: Department of General Psychology (DPG), University of Padua, Padua, Italy

Cystic Fibrosis: a new frailty syndrome

Lorenza Ferrillo¹, Vincenzo Carnovale¹, Graziamaria Corbi¹, Jolanda Somma¹, Marcella d'Ippolito¹, Giuseppe Rengo^1,2, Paola Iacotucci³

1: Department of Translational Medical Sciences, University of Naples “Federico II”, 80138 Naples, Italy; 2: Istituti Clinici Scientifici Maugeri IRCCS, Scientific Institute of Telese Terme, Telese Terme, BN, Italy; 3: Department of Clinical Medicine and Surgery, University of Naples “Federico II”, 80138 Naples, Italy

Two Clues, One Risk: Slow Gait and Depressive Symptoms as Early Predictors of Mobility Disability in Frail Older Adults

Riccardo Calvani, Emanuele Marzetti, Ilaria Esposito, Anna Maria Martone, Francesco Landi

Università Cattolica del Sacro Cuore, Italy

Prognostic Value of Anisocytosis (RDW) in Predicting All-Cause Mortality in Older Adults

Mirko Di Rosa¹, Pierluigi Mercatante^2,3, Alberto Montesanto², Ersilia Paparazzo^1,2, Luca Soraci^1,2, Andrea Corsonello^1,2, Chiara Chinigò¹, Lucia Muglia¹, Giuseppe Passarino², Fabrizia Lattanzio¹

1: IRCCS INRCA, Italy; 2: University of Calabria, Italy; 3: University of Florence, Italy

Telomere Dysfunction as a Molecular Driver of Vascular Aging and Acute Coronary Syndrome: Clinical and In Vitro Insights

Paola Canale¹, Jonica Campolo², Gianluca Gazzaniga³, Marina Parolini², Emanuela Piccaluga⁴, Irene Bossi⁴, Claudio Montalto⁴, Jacopo Oreglia⁴, Irene Marinaro⁵, Antonella Mercuri⁵, Stefano Turchi⁵, Maria Grazia Andreassi⁵

1: Sant'Anna School of Advanced Studies, Pisa, Italy; 2: CNR Institute of Clinical Physiology, Milan, Italy; 3: Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Rome, Roma, Italy; 4: Interventional Cardiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy; 5: CNR Institute of Clinical Physiology, Pisa, Italy

Muscle ultrasound thickness of rectus femoris plus vastus intermedius is associated with Intrinsic Capacity in hospitalized older adults

Leonardo Bencivenga, Laura Andreea Ceparano, Claudia Canitano, Antonio Alessandro Caracciolo, Giovanni Curcio, Laura De Lisio, Antonio Di Maio, Giuseppina Gambino, Maria Grazia Landi, Pasquale Pezzella, Giovanni Saccon, Ivana Serino, Annachiara Vassallo, Valeria Zanobbi, Nicola Ferrara, Giuseppe Rengo

Dipartimento di Scienze Mediche Traslazionali, Università degli Studi di Napoli Federico II, Italy

Metric properties and predictive value of an instrumented version of the SPPB (iSPPB) in persons with stroke outcomes: preliminary results of the iSPPB-stroke study

Mario De Marco¹, Diego Longo¹, Marta Massei¹, Lorenzo Maria Del Re², Olimpia Salvini², Agnese Andaloro³, Leonardo Tellini³, Antonio Chita³, Lucia Martucci³, Olga Karitonenko⁴, Alessio Faralli², Michele Piazzini^1,2, Marco Baccini^2,4, Francesca Cecchi^1,2,3,4

1: Department of Experimental and Clinical Medicine, University of Florence, Italy; 2: IRCCS Fondazione don Carlo Gnocchi, Florence, Italy; 3: School of Physical and Rehabilitation Medicine, University of Florence, Italy; 4: School of Physiotherapy, University of Florence, Italy

Aging Well in an Aging Society: Italy at the Forefront of Global Aging

Daniele Vignoli

University of Florence, Italy

Positive Demography: Changing the Perspective on Population Aging

Giammarco Alderotti

University of Florence, Italy

Improving our understanding of the biology of ageing

Fabrizio d'Adda di Fagagna

CNR, Italy

Clinical and environmental factors, functional status, and multimorbidity—Stratifying progression and prognosis of multimorbidity, frailty, and disability

Antonio Cherubini

IRCCS INRCA, Italy

Multidimensional Determinants of Active and Healthy Ageing Trajectories: A Position Paper

Antonio Paoli

Università degli Studi di Padova, Italy

Caring in the XXI century: Mapping challenges and developing solutions

Cecilia Tomassini

University of Molise, Italy

An Index of Intergenerational Justice: Main Concepts and Preliminary Evidence

Vincenzo Galasso

Bocconi University, Italy

Multicomponent interventions and technologies to reduce the burden of frailty, functional and cognitive decline

Carlo Ferrarese

University of Milano - Bicocca, Italy

Leveraging Human-Robot Interaction and Virtual Reality for Digital Biomarkers in Diagnostics and Rehabilitation

Filippo Cavallo

University of Florence, Italy

Clarifying healthy ageing: Building a common language for policy innovation

Fulvio Ricceri

University of Turin, Italy

Participatory Approach, Dissemination and Implementation of Research on Aging

Carlos Chiatti

Italian Ageing- Age-It Scarl, Italy

Education and Learning for Active Aging: Promising Practices and Findings

Michele Bertani

Ca' Foscari University of Venice, Italy

Aging in aging societies: The transformation of individuals’ life courses and how we study them

Marco Albertini

University of Bologna, Italy

Out of Sight, Out of Security? Telework, Job Insecurity, and Employability for Aging Workers

Luisa Errichiello¹, Greta Falavigna²

1: National Research Council of Italy (CNR), Institute for Studies on the Mediterranean (ISMed); 2: National Research Council of Italy (CNR), Institute for Research on Sustainable Economic Growth (IRCrES)

Ageing and Quality of Life: A Gender Issue?

Letizia Carrera

Università degli Studi di Bari, Italy

Mapping Pension Beneficiary Disparities across Italian Provinces: A Multidimensional Approach

Nadia Mignolli¹, Oreste Nazzaro¹, Roberta Pace²

1: Italian National Institute of Statistics (Istat), Italy; 2: University of Bari Aldo Moro, Italy

L'invecchiamento dei lavoratori e la gestione dell'età anziana sui luoghi di lavoro

Rosa Casillo

Università di Napoli Fedetrico II, Italia

It is never too late to be green: ageing and awareness of sustainable behaviour

SIMONE CARLO¹, SARA NANETTI², PIERMARCO AROLDI³

1: Università Cattolica del Sacro Cuore, Italy; 2: Università Cattolica del Sacro Cuore, Italy; 3: Università Cattolica del Sacro Cuore, Italy

Marital biography and health later on: which aspects really matter? Outcome-wide evidence from multiple countries.

Davide Gritti, Raffaele Grotti, Stefani Scherer

Università di Trento, Italy

Age metastereotypes at work: intergroup outcomes and affective reactions

Camilla Matera, Giulia Calamai, Anna Cardelli, Amanda Nerini

University of Florence, Italy

Workers’ wellbeing and organizational Practices in Firms: evidence from Italy

claudio lucifora, nicole di natale

Unicatt, Italy

Disentangling ageism in labour market service: the implementation of an active labour market policy targeting over 55

Dario Raspanti¹, Luigi Burroni¹, Gemma Scalise², Cristina Burini²

1: Università di Firenze, Italy; 2: Università di Milano Bicocca, Italy

Age management practices and firm performance: evidence from Italian SME

Marco Piotti, Claudio Lucifora

Università Cattolica del Sacro Cuore, Italy

Does polypharmacy affect epigenetic aging in older people? Evidence from a longitudinal epigenome-wide methylation study

Alessandro Gialluisi^1,2, Alfonsina Tirozzi¹, Simona Costanzo^1,3, Danilo Licastro⁴, Augusto Di Castelnuovo¹, Miriam Shasa Quiccione¹, Teresa Panzera¹, Sara Magnacca¹, Mariarosaria Persichillo¹, Fabrizia Noro¹, Chiara Cerletti¹, Maria Benedetta Donati¹, Giovanni de Gaetano¹, Licia Iacoviello¹

1: Epidemiology and Prevention Research Unit, IRCCS NEUROMED, Pozzilli, Italy; 2: Department of Medicine and Surgery, LUM University, Casamassima, Italy; 3: Research Center in Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Varese, Italy; 4: Genomics and Epigenomics Lab, Area Science Park, Trieste, Italy

Documenting the transition of multimorbidity patterns of chronic diseases leading to death at older ages

Hoang Khanh Linh Dang¹, Nicola Caranci², Giulia Roli¹, Rosella Rettaroli¹, Rossella Miglio¹

1: University of Bologna; 2: Emilia-Romagna Region

Designing new sustainable care pathways through Lean and Safety Management: the Domus_Rehab case

Anna Tiso¹, Caterina Pozzan¹, Chiara Pamich¹, Alfonc Baba², Margherita Bertuccelli³, Alessandra Del Felice², Chiara Verbano¹

1: Department of Management Engineering, University of Padova, Italy; 2: Department of Neuroscience, University of Padova, Italy; 3: Department of Information Engineering, University of Padova, Italy

Dissecting inflammaging relevance in accelerated aging and age-related outcomes in an Italian cohort

Jacopo Venetucci^1,2, Giulia Garro^1,2, Silvia Vittoria Cracas^1,2,3, Luca Briacca^1,2, Davide Rossato², Chiara Roveda¹, Marco Varalda^1,2, Valentina Bettio², Marco Martorana³, Chaitanya Kankara^1,2, Annamaria Antona¹, Roberta Rolla⁴, Fabrizio Faggiano³, Daniela Capello^1,2

1: Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 2: UPO BIOBANK, University of Piemonte Orientale, Novara, Italy; 3: Department of Sustainable Development and Ecologic Transition, University of Piemonte Orientale, Vercelli, Italy; 4: Clinical Chemistry Laboratory, Department of Health Sciences, University of Piemonte Orientale, Maggiore della Carità University Hospital, Novara, Italy

Active Ageing in the Italian Regional Prevention Plans. Alignments and Differentiations

Michele Bertani, Michele Marzulli, Lorenzo Schiavon

Ca' Foscari University of Venice, Italy

From Compression to Expansion? Policy Recommendations from Health Surveillance Trends in Cardiovascular and Diabetes Morbidity in the US

Alberto Arletti, Lorenzo Schiavon, Mattia Stival, Michele Marzulli, Stefano Campostrini

Department of Economics, Ca' Foscari University of Venice, Italy

Aligning policies and strategies for the promotion of Healthy and Active ageing: comparison of international and national policies

Fabrizio Faggiano¹, Giacomo Balduzzi¹, Renato Balduzzi², Franca Beccaria³, Michele Bertani⁴, Stefano Campostrini⁴, Michele Marzulli⁴, Silvia Caristia¹, Laura Formenti⁵, Guido Giarelli⁶, Giovanni Lamura⁷, Davide Lucantoni⁷, Andrea Principi⁷, Sara Rolando³, Davide Servetti¹, Marco Socci⁷, Erica Viola¹

1: Università del Piemonte orientale, Italy; 2: Università Cattolica del Sacro Cuore – Milano; 3: ECLECTICA+ Ricerca e Formazione Impresa Sociale S.r.L. - Torino; 4: Università Ca’ Foscari - Venezia; 5: Università degli Studi di Milano Bicocca - Milano; 6: Università della Magna Grecia - Catanzaro; 7: National Institute of Health and Science on Ageing (IRCCS-INRCA) - Ancona

Aligning policies and strategies on active and healthy ageing to make countries resilient to the demographic transition: a review of the recommendations of International Agencies

Silvia Caristia¹, Erica Viola¹, Thellenxa Kalemi², Davide Servetti³, Samuele Poy¹, Fabrizio Faggiano¹

1: Università del Piemonte Orientale, Dipart. per lo Sviluppo Sostenibile e la Transizione Ecologica, Italy; 2: Università del Piemonte Orientale, Scuola di Medicina, Italy; 3: Università del Piemonte Orientale, Dipart. di Giurisprudenza e Scienze Politiche, Economiche e Sociali

Care Work for Vulnerable Elderly People in a Comparative Perspective: The Role of the Family Caregiver in Italy, France, and Spain

Francesca Rotolo, Claudia Irti

Ca' Foscari University of Venice, Italy

Reproducing the future: a realistic necessity for an ageing society

Carlo Burelli

Università del Piemonte Orientale, Italy

Age and Gender Preferences in Job Opportunities: a Survey in Italian SMEs

Francesco Maura, Paola Profeta, Olivia Masi

Università Bocconi, Italy

Economic crisis and the wellbeing of the elderly in Italy: the long-term impact of the Great Recession

Loris Vergolini^1,2, Paolo Pasetti¹, Eleonora Vlach³

1: University of Bologna, Italy; 2: FBK-IRVAPP, Italy; 3: Goethe-Universität, Germany

Retirement migration, citizenship, and regulatory inconsistency: the Italian case between agency mobile and institutional constraints

Marco Alberio, Olivia Pini, Alice Lomonaco

University of Bologna

General Practitioners and Avoidable Hospitalizations in Italy's Aging Population.

Simone Ghislandi, Giulia Tarantino, Aleksandra Torbica, Irene Torrini

Bocconi University, Italy

Energy communities and population age in Italian municipalities

ELEONORA CARUSO, ALESSANDRO SAPIO

Università degli Studi di Napoli Parthenope, Italy

Energy poverty and active ageing in Italy

Martina Polito, Alessandro Sapio

Parthenope University of Naples, Italy

Silver Awareness Sustainability Checklist: A policy evaluation tool for age-inclusive local development

Sara Nanetti, Simone Carlo, Piermarco Aroldi

Università Cattolica del Sacro Cuore, Italy

Measuring housing and health vulnerability among older people in Italy: a multidimensional perspective

Marco Arlotti, Mariateresa Ciommi, Luigi Bernardi, Francesca Mariani

Marche Polytechnic University, Italy

Enhancing Bci Learning Through Collaborative Social Gaming: A Longitudinal Study Of Motor Imagery Training

Alessio Palatella¹, Stefano Tortora^1,2, Alessandra Del Felice^1,2,3, Emanuele Menegatti^1,2, Luca Tonin^1,2

1: Department of Information Engineering, University of Padova, Padova, Italy; 2: Padova Neuroscience Center, University of Padova, Padova, Italy; 3: Dept. of Neuroscience, University of Padova, Padova, Italy

Old but Gold: Population Ageing and Innovation Incentives

Maria Luisa Mancusi¹, Matteo Romagnoli²

1: Università Cattolica del Sacro Cuore (UCSC), Complexity Lab in Economics (UCSC); 2: Fondazione Eni Enrico Mattei

User-Aware Multi-Turn Dialogue System for Socially Assistive Robots Using LLMs

Alessandra Sorrentino, Matilde Guidi, Filippo Cavallo

University of Florence, Italy

Learning to walk: An imitative approach to adaptive gait generation in lower limb exoskeletons for elderly assistance

Stefano Tortora^1,2, Edoardo Trombin¹, Miroljub Mihailovic¹, Matheus Henrique Ferreira Moura¹, Luca Tonin^1,2, Emanuele Menegatti^1,2

1: Department of Information Engineering, University of Padova, Italy; 2: Padova Neuroscience Center, University of Padova, Italy

Achieving well-being: a global framework for integrating well-being into public health utilizing a health promotion approach

Faten Ben Abdelaziz

World Health Organization, Italy

Measuring Equitable and Sustainable well-being in Italy, the BES framework

Emanuela Bologna, Alessandra Tinto

Istat

Measuring well-being in a health promotion perspective

Gaia Bertarelli

Ca' Foscari University of Venice

Well-being, health and ageing styles: which public health policies?

Guido Giarelli

UNIVERSITA' MAGNA GRAECIA, Italy

Decoding the Exposome: Molecular Biomarkers at the Intersection of Environment and Aging (remote)

Andrea Baccarelli

Environmental Health, Harvard T.H. Chan School of Public Health, United States of America

Keynote Speaker

Regina Roller Wirnsberger

Medical University of Graz, Austria

Farewell remarks

Daniele Vignoli¹, Pier Giorgio Mastroberardin²

1: University of Florence, Italy; 2: Erasmus Rotterdam University