Opening remarks

Matteo Lorito¹, Alessandra Petrucci², Cristina Freguja³, Anna Maria Colao⁴

1: Rettore dell'Università di Napoli Federico II; 2: Rettrice dell'Università di Firenze; 3: Istituto Nazionale di Statistica (ISTAT); 4: Consiglio Superiore di Sanità

Keynote Speaker

Wolfgang Lutz

International Institute for Applied Systems Analysis – IIASA, Vienna, Austria

Keynote Speaker (remote)

Alina Lupu

Commissione Europea

How raising the Full Retirement Age affects early retirement choices: insights from the interaction of two policies

Elena Bassoli¹, Ylenia Brilli²

1: ETH, Switzerland; 2: Ca' Foscari University of Venice

Paths to Retirement

Giuseppe Pio Dachille¹, Monica Pia Cecilia Paiella^1,2, Gianfranco Santoro¹

1: INPS, Italy; 2: University of Naples "Parthenope"

Retirement reloaded: Bridge Employment, Ageing Workforce and the Digital Transition

Luisa Errichiello, Daniele Demarco, Orsola Salmista

National Research Council of Italy ( CNR), Institute for Studies on the Mediterranean (ISMed)

The Pedagogical Value of Volunteering Associations in the Post-Retirement Transition: The Case Study of AUSER (Associazione per l'autogestione dei servizi e la solidarietà)

Giovanna Del Gobbo, Cristina Banchi

University of Florence, Italy

Public attitudes towards ART and its social determinants: evidence from an ad-hoc survey in Italy

Ester Lazzari², Valentina Tocchioni¹, Marco Cozzani¹, Daniele Vignoli¹

1: University of Florence, Italy; 2: University of Vienna

Family expectations, social capital and perceived Well-Being in the transition to retirement

Donatella Bramanti¹, Luisa Errichiello², Greta Falavigna³, Sara Nanetti¹

1: Università Cattolica - Milano, Italy; 2: CNR- ISMed; 3: CNR- IRCrES

Changing family trajectories and their impact on men’s and women’s mental health in midlife. The case of 1958 and 1970 British cohorts

Danilo Bolano¹, Roberta Rutigliano², Anna Barbuscia², Maria Sironi³

1: University of Florence, Italy; 2: University of the Basque Country; 3: University of Padua

Is “living apart together” a real advantage for patients consulting for sexual dysfunction? A cohort study from a Florentine population

Clotilde Sparano¹, Giovanni Corona², Giulia Rastrelli³, Linda Vignozzi³, Daniele Vignoli⁴, Mario Maggi¹

1: University of Florence, Italy; 2: Endocrinology Unit, Azienda USL Bologna, Bologna, Italy; 3: Andrology, Women’s Endocrinology and Gender Incongruence Unit, "Mario Serio", Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy; 4: Department of Statistics, Computer Science, Applications, University of Florence, Florence, Italy

Enhancement of attentional skills for driving in healthy older adults: effects of the cognitive training DRIVEWIN 3.0 that combines virtual reality and neurostimulation

Ilaria Baroni^1,2, Carlotta Lega³, Laura Veronelli^1,2, Simone Fontana¹, Leonardo Pantoni², Marco Feligioni², Alessio Facchin⁴, Roberta Daini¹

1: University of Milano-Bicocca, Italy; 2: Casa di Cura Igea, Italy; 3: University of Pavia, Italy; 4: University of Magna Graecia of Catanzaro, Italy

Feasibility and User Experience of Tablet-Based Cognitive Stimulation in Hospitalized Older Adults: Preliminary Results from the OPTIMAge-IT Trial

Chukwuma Okoye¹, Maria Cristina Ferrara¹, Wenxiang Guo¹, Beatrice Tonus¹, Lorenzo Lodovici¹, Elena Carlino², Lucia Muglia³, Alberto Finazzi¹, Guido Ferratini⁴, Danny Bassis⁵, Giuseppe Dario Testa⁴, Gianluca Bianco⁶, Filippo Niccolai², Valeria Calsolaro², Noemi Pardini², Eleonora Cucini¹, Annalisa Cozza³, Elvira Clausi⁷, Carmen Ruberto⁸, Lorella Lambertucci⁴, Maddalena Minelli⁵, Roberta Daini¹, Agostino Virdis², Filippo Fimognari⁷, Alessandra Marengoni⁶, Giovanni Ruotolo⁸, Andrea Corsonello³, Andrea Ungar⁴, Fabio Guerini⁵, Giuseppe Bellelli¹

1: University of Milano-Bicocca, Milan, Italy; 2: Department of Clinical and Experimental Medicine, University of Pisa, Italy; 3: Unit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy; 4: Department of Experimental and Clinical Medicine, University of Florence, Italy; 5: Department of Medicine, S. Anna Hospital, Brescia, Italy; 6: Department of Clinical and Experimental Sciences, University of Brescia, Italy; 7: Unit of Geriatrics, Departmemt of Internal Medicine "Annunziata-Mariano Santo-S. Barbara" Hospital, Cosenza, Italy.; 8: Geriatric Unit Center for Cognitive Disorders and Dementia, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy

Toward Self-Monitoring Healthcare: An Open Platform Ultraportable Ultrasound System.

Valentino Meacci, Lorenzo Castrignano, Paolo Verdi, Giulio Bonciani, Piero Tortoli, Enrico Boni, Alessandro Ramalli

University of Florence, Italy

Impedance Control for a Modified EduExo Upper Limb Exoskeleton in ALS Rehabilitation

Hamidreza Heidari, Paolino De Risi, Fanny Ficuciello

Università degli Studi di Napoli Federico II, Italy

Migrants and Ageing in Italy: A Multifarious Phenomenon

Daniela Carrillo, Patrizia Farina

university of Milan Bicocca, Italy

Enhancing health literacy to support family dementia caregivers: a community-based group intervention in primary care

Claudia Biagi¹, Chiara Milani¹, Claudia Rosi¹, Rachele Mei¹, Riccardo Barucci², Enrico Benvenuti², Giulia Naldini³, Lorenzo Baggiani³, Chiara Lorini¹, Guglielmo Bonaccorsi¹

1: Department of Health Sciences, University of Florence, Italy; 2: Geriatric Unit, Azienda USL Toscana Centro, Italy; 3: Department of Community Healthcare Network, Azienda USL Toscana Centro, Italy

Assisting Dementia caregivers through AI-CARE: a study protocol for usability

Danilo Atripaldi^1,2, Fabio Matascioli¹, Ludovico Piccolo¹, Nadia Conte¹, Agostino Borroso¹, Ilaria Chirico³, Riccardo Pronzato⁴, Sara Trolese³, Rabih Chattat³

1: TAMLab - Social Enterprise, Naples, Italy; 2: Department of Advanced Medical and Surgical Studies, University of Campania “Luigi Vanvitelli”, Naples, Italy; 3: Department of Psychology, University of Bologna, Italy; 4: Department of Sociology and Business Law, University of Bologna, Italy

The co-design and development of an e-learning platform for informal, formal and migrant caregivers of people with dementia: the AGE-IT project

Rabih Chattat¹, Sara Trolese¹, Sara Santini², Georgia Casanova², Serena Cancellieri², Antonella Golino³, Daniela Grignoli³, Veronica Moretti¹, Riccardo Pronzato¹, Ilaria Chirico¹

1: University of Bologna, Italy; 2: IRCCS INRCA National Institute of Health and Science on Ageing, Centre for Socio-Economic Research on Aging, Ancona, Italy; 3: University of Molise, Campobasso, Italy

Preliminary Insights from IN-TEMPO: A Multicenter Randomized Controlled Trial on Personalized Multidomain Interventions for Healthy Aging

Luca Cuffaro^1,2, Federico Emanuele Pozzi^1,2, Giovanni Isgrò^1,2, Gessica Sala^1,2, Carlo Ferrarese^1,2

1: School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 2: Milan Center for Neuroscience (Neuro-MI), University of Milano-Bicocca, Milan, Italy

Blood biomarkers for monitoring the impact of multidomain interventions on age-related cognitive and functional decline

Gessica Sala^1,2, Simona Andreoni^1,2, Chiara Bazzini^1,2, Elisa Conti^1,2, Chiara Paola Zoia^1,2, Luca Cuffaro^1,2,3, Federico Emanuele Pozzi^1,2,3, Lucio Tremolizzo^1,2,3, Maria Pia Longhese⁴, Giovanni Messina⁴, Cristina Airoldi^2,4, Ferdinando Chiaradonna^2,4, Luca Moretti⁴, Antonino Natalello^2,4, Ivan Orlandi⁴, Carlo Ferrarese^1,2,3

1: School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; 2: Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milan, Italy; 3: Department of Neurology, Fondazione IRCCS “San Gerardo dei Tintori”, Monza, Italy; 4: Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

Decoding the Epigenetic Clock: Long-Term Predictive Power of DNA Methylation for Age Estimation

Ersilia Paparazzo^1,2, Teresa Serra Cassano^1,3, Mirella Aurora Aceto¹, Vincenzo Lagani⁴, Pierluigi Mercatante^1,3, Silvia Fain¹, Antonella La Russa⁵, Luca Soraci⁶, Andrea Corsonello⁷, Francesco De Rango¹, Giuseppe Passarino¹, Alberto Montesanto¹

1: Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy; 2: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy; 3: University of Florence, Department of Statistic, Computer Science and Application, DiSIA, Viale Morgagni, 59, 50134, Florence (FI), Italy; 4: Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal 23952, Saudi Arabia; Institute of Chemical Biology, Ilia State University, Tbilisi 0162, Georgia; 5: Nephrology Unit, Department of Health Sciences, Magna Graecia University, Catanzaro 88100, Italy; 6: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy.; 7: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy; Department of Pharmacy, Health and Nutritional Sciences, School of Medicine and Digital Technologies, University of Calabria, Arcavacata di Rende, Italy

Aberrant TCR intracellular trafficking drives T cell dysfunction in immuno-senescence

Andrea Graziani^1,2, Raluca Minea¹, Alessia Labate¹, Giulia Rossino^1,2, Sabrina Mula¹, Emma Colautti¹, Andrea Toscano¹, Camilla Racca¹, Valeria Malacarne^1,2

1: Università di Torino, Molecular Biotechnology Center, Department of Molecular Biotechnology and Healths Sciences, Italy; 2: Università del Piemonte Orientale, Dept. of Translational Medicine

Dissecting evolutionary stress-adaptive adaptations in the hyper-longevous bats to devise novel anti-aging approaches.

Andrea Giacomo Locatelli^1,2, Roberto Pagliarini³, Martina Uggè⁴, Maria Materozzi¹, Ugo Orfanelli¹, Davide Stefanoni¹, Marta Roggiani¹, Massimo Resnati¹, Simone Cenci^1,2

1: Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milano, Italy; 2: Università Vita-Salute San Raffaele, Milano, Italy; 3: Department of Mathematics, Informatics and Physics Sciences, University of Udine, Udine, Italy; 4: Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milano, Italy

Obesity as driver of premature immune senescence

Valeria Mazzone¹, Annamaria Szabò¹, Antonella Desiderio², Antonietta Liotti^2,3, Rosa Spinelli², Daria Marcogiuseppe¹, Anna D'Amore⁴, Marco Milone⁴, Gregory Alexander Raciti², Francesco Beguinot², Claudia Miele¹, Veronica De Rosa¹

1: Istituto degli Endotipi in Oncologia, Metabolismo e Immunologia “G. Salvatore” (IEOMI)-CNR, Napoli, Italy; 2: Dipartimento di Scienze Mediche Traslazionali (DISMET) Università degli Studi di Napoli "Federico II", Napoli, Italy; 3: Centro Interdipartimentale di Ricerca in Scienze Immunologiche di base e cliniche (CISI), Università degli Studi di Napoli "Federico II", Napoli, Italy; 4: Dipartimento di Medicina e Chirurgia Clinica, Università degli Studi di Napoli "Federico II", Napoli, Italy

Mortalità e salute: dati, concetti e metodi nel percorso di un protagonista della demografia

Graziella Caselli, Viviana Egidi

Sapienza Università di Roma

Mobilità e lavoro di fronte alle sfide dell'invecchiamento: il contributo di Antonio Golini

Corrado Bonifazi, Giuseppe Gesano

IRPPS CRN

Verso una sintesi delle dinamiche territoriali: il malessere demografico

Annalisa Busetta¹, Sara Basso²

1: University of Palermo; 2: Istat

Geriatria e invecchiamento della popolazione

Fabrizia Lattanzio

Inrca

New technologies and old population: exploring legal challenges in a changing society

Claudia Morgana Cascione

University of Bari Aldo Moro, Italy

AI-Supported Home Adaptation for Older Adults: Insights from a Qualitative Study with Architects

Atieh Mahroo¹, Federica Romagnoli², Daniele Spoladore¹, Tiziana Ferrante², Marco Sacco¹, Teresa Villani²

1: National Research Council - Institute of Intelligent Industrial Technologies and Systems for Advanced Manufacturing (CNR-STIIMA); 2: Sapienza University of Rome - Department of Planning, Design and Technology of Architecture (PDTA)

A Persona approach for the user-centred design of IT-enabled health and social care services.

Vincenzo De Luca¹, Michele Virgolesi¹, Alessandra Cuomo², Daniela Lemmo³, Mariangela Perillo⁴, Lorenzo Mercurio¹, Erminia Attaianese⁴, Enrica Menditto⁵, Annamaria Colao², Guido Iaccarino², Maddalena Illario¹

1: Department of Public Health, Federico II University of Naples, Italy; 2: Department of Clinical Medicine and Surgery, Federico II University of Naples, Italy; 3: Department of Human Sciences, Federico II University of Naples, Italy; 4: Department of Architecture, Federico II University of Naples, Italy; 5: Department of Pharmacy, Federico II University of Naples, Italy

Exploring the impact of Ambient Assisted Living for older people on caregiver burden: a systematic literature review.

Georgia Casanova, Marco Socci, Diletta Cicconi, Anita Ambrosi, Cristina Gagliardi

IRCCS INRCA - National Institute of Health and Science on Ageing, Centre for Socio-Economic Research on Ageing, Ancona, Italy

Green transition and labour market dynamics of older workers

Danilo Cavapozzi, Federico de Luca

Università Ca' Foscari Venezia, Italy

Childbirth and Income Within Couples: A Dyadic Analysis from Administrative Data in Tuscany

Elisa Brini¹, Carlos J. Gil-Hernández¹, Raffaele Guetto¹, Marialuisa Maitino², Letizia Ravagli², Daniele Vignoli¹

1: University of Florence, Department of Statistics, Computer Science, Applications ‘G. Parenti’; 2: Istituto Regionale per la Programmazione Economica della Toscana (IRPET)

Accidents at work: evidence from an unanticipated increase in retirement age

Manuel Alarcon Serrano¹, Chiara Ardito¹, Elena Cottini², Gloria Moroni³

1: Joint Research Centre, Ispra; 2: Department of Economics and Finance, Universit`a Cattolica del Sacro Cuore; 3: Ca Foscari University of Venice, Italy

Working Longer, Living Longer? Retirement Timing, Migration Background and Mortality in Sweden

Eleonora Trappolini¹, Sven Drefahl²

1: Sapienza University of Rome, Italy; 2: Stockholm University, Sweden

Measuring Changes in Risk Preferences Over the Life Cycle: Experimental Evidence from Economics and Psychology

Pablo Marcos-Prieto, Erica Ordali, Chiara Rapallini

University of Florence, Italy

Why Do Households Save and Work?

Margherita Borella¹, Mariacristina De Nardi^2,4, Fang Yang³, Johanna Torres Chain²

1: University Cà Foscari Venice, University of Torino, Italy; 2: University of Minnesota; 3: Federal Reserve Bank of Dallas; 4: Federal Reserve Bank of Minneapolis

The Risk of Work Related Accidents at Older Ages

Elena Cottini¹, Michele Maccarini¹, Gloria Moroni²

1: Università Cattolica del Sacro Cuore, Italy; 2: Università Ca' Foscari Venezia, Italy

Working Conditions and Health Over the Life-cycle: Evidence From Europe

Paolo Micera¹, Claudio Lucifora¹, Michele Belloni²

1: Università Cattolica del Sacro Cuore, Italy; 2: Università degli studi di Torino, Italy

The MOVE Project: Study Design and Baseline Characterization of a Longitudinal Trial on Cognitive and Physical Decline

Alessandra Dodich, Caterina Dapor, Giulia Ellena, Marco Pietro Parente, Elena Zambon, Jorge Jovicich, Costanza Papagno

Center for Mind/Brain Sciences, CIMeC, University of Trento, Rovereto, Italy

Impact of Inactivity on Neuromuscular Health

Marco Narici^1,2, Ornella Caputo¹, Fabio Sarto¹, Eugenia Motanova¹, Martino Franchi², Bostjan Simunič², Mladen Gasparini³, Rado Pišot²

1: University of Padova, Italy; 2: ZRS Science Research Centre, Koper, Slovenia; 3: Izola General Hospital. Izola, Slovenia

Novara Cohort Study (NCS): A mixed-methods analysis of participant impact and experience

Riccardo Tucci¹, Silvia Caristia², Silvia Vittoria Cracas³, Giulia Garro⁴, Marco Martorana⁵, Erica Viola⁶, Chiara Aleni⁷, Jacopo Venetucci⁸, Lucrezia Capuzzi⁹, Vittoria Colombo¹⁰, Valeria Bettio¹¹, Fabrizio Faggiano¹², Daniela Capello¹³

1: Università del Piemonte Orientale, Italy; 2: Università del Piemonte Orientale, Italy; 3: Università del Piemonte Orientale, Italy; 4: Università del Piemonte Orientale, Italy; 5: Università degli studi di Firenze, Italy; 6: Università del Piemonte Orientale, Italy; 7: Astra Zeneca; 8: Università del Piemonte Orientale, Italy; 9: Università del Piemonte Orientale, Italy; 10: Università del Piemonte Orientale, Italy; 11: Università del Piemonte Orientale, Italy; 12: Università del Piemonte Orientale, Italy; 13: Università del Piemonte Orientale, Italy

Clinical impact and prognostic value of Alzheimer’s disease pathophysiology in the very old.

Chiara Ceriello .^1,3,5, Olga H. Torres^1,3,5, Daniel Alcolea^2,3,4,5, Ignacio Illan^2,3,4,5

1: Geriatric Unit, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025, Barcelona, Spain; 2: Sant Pau Memory Unit, IR SANT PAU, Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, Spain; 3: Institut de Recerca Sant Pau (IR SANT PAU), Sant Quintí 77-79, 08041, Barcelona, Spain; 4: Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, 28029, Spain; 5: Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain

Quercetin induces senolysis of doxorubicin-induced senescent fibroblasts by reducing autophagy, preventing their pro-tumour effect on osteosarcoma cells

Elisa Bientinesi, Sara Ristori, Gianmarco Bertoni, Matteo Lulli, Daniela Monti

Department of Experimental and Clinical Biomedical Sciences, University of Florence, Italy

Exploring the Synergistic Effect of a Senolytic Compound and a Probiotic on Healthspan and Lifespan in Aged Mice

Serena Marcozzi¹, Giorgia Bigossi¹, Maria Elisa Giuliani¹, Giovanni Lai¹, Marco Malavolta^1,2

1: IRCCS INRCA, Ancona, Italy; 2: Università Politecnica Delle Marche, Ancona, Italy.

Carnitine network and SASP: role of membrane transporters from SLC family

Mariafrancesca Scalise¹, Francesca Barone¹, Lara Console¹, Michele Galluccio¹, Annamaria Tonazzi², Nicola Giangregorio², Lorena Pochini^1,2, Cesare Indiveri^1,2

1: University of Calabria, Italy; 2: IBIOM-CNR, Bari Italy

A20 and TNIP3 attenuate NF-κB – mediated paracrine responses to hypoxia/hyperglycemia-induced endothelial senescence

Lara Russo, Serena Babboni, Serena Del Turco, Giuseppina Basta

Consiglio nazionale delle ricerche- Istituto di Fisiologia Clinica, Italy

Role of the TGN transport machinery in the regulation of SASP-components transport and secretion.

Rosaria Di Martino, Daniela Corda, Alberto Luini

Istituto degli Endotipi in Oncologia, Metabolismo ed Immunologia, Consiglio Nazionale delle Ricerche, Italy

Effects of Chemotherapy-Induced Golgi Alterations and Exploiting Senescence for Cancer Therapy

Fabiola Mascanzoni, Inmaculada Ayala, Daniela Spano, Roberta Iannitti, Antonino Colanzi

CNR, IEOMI Italy

A cytokine-based inflammaging score improves frailty-based prediction of long-term mortality in older adults.

Matilde Sbriscia¹, Sonia Fantone¹, Mirko Di Rosa², Francesca Marchegiani³, Rina Recchioni³, Giulia Matacchione³, Chiara Giordani³, Francesco Piacenza¹, Roberta Giacconi¹, Davide Gentilini^4,5, Luciano Calzari⁴, Carlo Forunato¹, Gretta Veronica Badillo Pazmay¹, Monia Cecati¹, Sara Caccese⁶, Emanuele Francini³, Rosanna Maniscalco¹, Maurizio Cardelli¹, Elena Tortato⁷, Federica Lenci⁸, Yuri Rosati⁹, Maurizio Burattini¹⁰, Roberto Antonicelli¹¹, Andrea Corsonello^12,13, Luca Soraci¹², Leonardo Biscetti¹⁴, Massimiliano Fedecostante¹⁵, Riccardo Sarzani^16,17, Marco Malavolta^1,16, Tiziana Casoli¹⁸, Maria Conte¹⁹, Antonio Domenico Procopio^3,16, Fabrizia Lattanzio⁶, Anna Rita Bonfigli⁶, Antonio Cherubini^15,16, Claudio Franceschi²⁰, Jacopo Sabbatinelli^3,16, Fabiola Olivieri^1,16

1: Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; 2: Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 3: Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy; 4: Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Italy; 5: Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; 6: Scientific Direction, IRCCS INRCA, Ancona, Italy; 7: Diabetology Unit, IRCCS INRCA, Ancona, Italy; 8: Unit of Nephrology and Dialysis, IRCCS INRCA, Ancona, Italy; 9: Respiratory Medicine, IRCCS INRCA, Osimo, Italy; 10: Internal Medicine, IRCCS INRCA, Osimo, Italy; 11: Cardiology Unit, IRCCS INRCA, Ancona, Italy; 12: Unit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy; 13: Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy; 14: Neurology Unit, IRCCS INRCA, Ancona, Italy; 15: Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy; 16: Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; 17: Internal Medicine and Geriatrics, 'Hypertension Excellence Centre' of the European Society of Hypertension, Società Italiana per lo Studio dell'Aterosclerosi (SISA) LIPIGEN Centre, IRCCS INRCA, Ancona, Italy; 18: Center for Neurobiology of Aging, IRCCS INRCA, Ancona, Italy; 19: Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; 20: Institute of Biogerontology, Lobachevsky State University, Nizhny Novgorod, Russia

Advanced microphysiological systems to evaluate pharmacological interventions in vitro CKD models

Alessandra Calogiuri¹, Laura Blasi², Paola Pontrelli³, Gianvito Caggiano⁴, Alessandra Stasi⁵, Elisa Sciurti⁶, Daniele Bellisario⁷, Vanessa Esposito⁸, Flavio Casino⁹, Pietro Aleardo Siciliano¹⁰, Luca Nunzio Francioso¹¹

1: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 2: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 3: Nephrology, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.; 4: Nephrology, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.; 5: Nephrology, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.; 6: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 7: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 8: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 9: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 10: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy; 11: Institute for Microelectronics and Microsystems IMM-CNR, Via per Monteroni “Campus Ecotekne”, 73100 Lecce, Italy

Exploring the Muscle–Brain Axis: Associations Between Neurodegeneration Biomarkers, Sarcopenia, and Function in Older Adults – Preliminary Results from the OPA Study

Marina De Rui¹, Chiara Ceolin¹, Eleonora Fiorenzato², Giulia Musso³, Cristina Simonato¹, Silvia Sturani¹, Adele Ravelli¹, Francesca Vianello², Laura Nasi², Simone Cauzzo², Sabrina Pigozzo¹, Maria Devita¹, Alessandra Coin¹, Gabriella Milan⁴, Catia Pilon⁴, Luca Busetto⁴, Angelo Antonini², Giuseppe Sergi¹

1: Geriatric Unit, Department of Medicine (DIMED), University Hospital of Padua, Padua, Italy; 2: Parkinson's Disease and Movement Disorders Unit, Center for Rare Neurological Diseases (ERN-RND), Department of Neurosciences, University of Padova, Padova, Italy; 3: Department of Laboratory Medicine, Department of Medicine (DIMED), University of Padua, Padua; 4: Clinica Medica 3, Department of Medicine (DIMED), University of Padua, Padua

Effects of Paget’s disease of bone-associated ZNF687 and PFN1 mutations on hematopoietic cell heterogeneity and differentiation in the context of aging

Sharon Russo, Federica Scotto di Carlo, Fernando Gianfrancesco

Institute of Genetics and Biophysics, Italy

Portable Surface Electromyography System for Sarcopenia Detection

Anna Maria Carluccio, Andrea Manni, Gabriele Rescio, Andrea Caroppo, Pietro Aleardo Siciliano, Alessandro Leone

National Research Council of Italy, Instiute for Microelectronics and Microsystems, Lecce, Italy

Evaluating Musculoskeletal Models and IMU Configurations for Reach-to-Grasp Biomechanics in Aging

Pietro Benvenuti

Università degli Studi di Firenze, Italy

Parallel semantic reading of multiple words in aging

Matilde Menghini¹, Silvia Primativo², Valentina Bandiera², Laura Veronelli¹, Carlotta Lega¹, Luisa Girelli¹, Fabrizio Zeri¹, Roberta Daini¹

1: Università degli Studi di Milano-Bicocca, Italy; 2: Università LUMSA

IDENTIFICATION AND QUANTIFICATION OF MULTIDIMENSIONAL FRAILTY IN ELDERLY PATIENTS IN DIFFERENT CARE SETTINGS (Fra-SET)

Pasquale Abete¹, Francesco Curcio¹, Francesco Cacciatore¹, Gesualda Bruno¹, Antonio Cittadini², Michele Arcopinto², Andrea Salzano², Nicola Vargas³, Elisa Salsano³, Oriana Rossi³, Gaetano Gargiulo⁴, Umberto Mazzarelli⁴, Aniello Sottolano⁴, Antonio Petrocelli⁵, Lucia Agrelli⁵, Gina Varricchio⁶, Raffaele Pagliuca⁶, Luisa Aran⁶, Pasquale Morella⁷, Antonio Magliocca⁷, Mariano Carafa⁸, Mattia De Furio⁸

1: Department of Translational Medical Sciences, University of Naples Federico II, Italy; Division of Sub-intensive Medical Therapy, AOU Federico II, Naples, Italy; 2: Division of Rehabilitation and Metabolic Internal Medicine AOU Federico II, Naples, Italy; 3: Division of Geriatrics - AORN San Giuseppe Moscati, Avellino, Italy; 4: Division of Internal Medicine, AOU San Giovanni di Dio e Ruggi di Aragona, Salerno, Italy; 5: Division of Emergency Medicine AOU San Giovanni di Dio e Ruggi di Aragona, Salerno, Italy; 6: Division of Geriatrics, AO Sant'Anna e San Sebastiano, Caserta, Italy; 7: Division of Internal Medicine 3, AORN Antonio Cardarelli, Naples, Italy; 8: Division of Internal Medicine DEA and clinical Complexity, AORN Antonio Cardarelli, Naples, Italy

Health Literacy and Early Frailty Detection in Primary Care: A Community-Based Observational Study

Guglielmo Bonaccorsi¹, Claudia Biagi¹, Chiara Milani¹, Diletta Buresta¹, Fiorenza Wetzel Cabrera¹, Riccardo Barucci², Enrico Benvenuti², Lorenzo Baggiani², Marco Nerattini³, Chiara Lorini¹

1: University of Florence, Italy, Italy; 2: AUSL Toscana Centro; 3: Società della Salute Firenze

Differential Impact of Frailty on Neurodegenerative, Cardiometabolic, and Cancer Outcomes

Augusto Di Castelnuovo¹, Simona Costanzo^1,2, Francesca Bracone¹, Alessandro Gialluisi^1,3, Marialaura Bonaccio¹, Teresa Panzera¹, Chiara Cerletti¹, Maria Benedetta Donati¹, Giovanni de Gaetano¹, Licia Iacoviello^1,3

1: IRCCS Neuromed, Pozzilli, Italy; 2: University of Insubria, Varese, Italy; 3: LUM University, Casamassima, Italy

Parallel Burdens of Aging: Disentangling the Impact of Frailty and Comorbidity on Long-Term Survival in the FRASNET Cohort

Patrizia Rovere-Querini^1,2, Sarah Damanti^1,2, Martina Mallus^1,2, Laura Zagato^1,3, Lorena Citterio^1,3, Paolo Manunta^1,3, Chiara Lanzani^1,3

1: Università Vita Salute San Raffaele, Italy; 2: Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 3: Nephrologic Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Frailty and Multimorbidity in Older Inpatients: A Comparative Analysis of Quantitative and Qualitative Predictors of In-Hospital Outcomes

Luca Soraci¹, Mirko Di Rosa², Andrea Corsonello^1,3, Massimiliano Fedecostante⁴, Sarah Damanti⁵, Rosa Liperoti⁶, Licia Iacoviello⁷, Pasquale Abete⁸, Riccardo Calvani⁹, Fabrizia Lattanzio¹⁰, Antonio Cherubini^4,11

1: Unit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy; 2: Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 3: Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy; 4: Geriatria, Accettazione Geriatrica e Centro di Ricerca per l'Invecchiamento, IRCCS INRCA, Ancona, Italy; 5: Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 6: Department of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, Rome, Italy; 7: Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli (IS), Italy; 8: Department of Translational Medical Sciences (DISMET), Federico II University, Naples, Italy; 9: Fondazione Policlinico Universitario A Gemelli IRCCS, Largo Agostino Gemelli 8, Rome, Italy; Department of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy; 10: Scientific Direction, IRCCS INRCA, Ancona, Italy; 11: Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy

Integrating Clinical and Biological Indices to Enhance Frailty Detection: Insights from the Novara Cohort Study

Silvia Vittoria Cracas, Giulia Garro, Jacopo Venetucci, Annamaria Antona, Marco Varalda, Valentina Bettio, Roberta Rolla, Luca Briacca, Chaitanya Reddy Kankara, Fabrizio Faggiano, Daniela Capello

Università del Piemonte Orientale, Italy

AQP4 protein and Antisense lncRNAs expression in Brain development and aging

Onofrio Valente, Alessandra Rombolà, Pasqua Abbrescia, Claudia Palazzo, Antonio Frigeri

Department of Translational Biomedicine and Neuroscience School of Medicine, University of Bari Aldo Moro,

HIV reservoir and premature aging: risk factors for aging-associated illnesses in adolescents and young adults with perinatally acquired HIV

Maria Raffaella Petrara^1,2, Elena Ruffoni¹, Francesco Carmona¹, Ilaria Cavallari¹, Sandra Zampieri^3,4, Marzia Morello¹, Paola Del Bianco⁵, Osvalda Rampon⁶, Nicola Cotugno⁷, Paolo Palma⁷, Paolo Rossi⁷, Carlo Giaquinto⁶, Silvia Giunco^1,2, Anita De Rossi^1,2

1: Immunology and Molecular Oncology Diagnostics, Veneto Institute of Oncology IOV–IRCCS, Padova, Italy; 2: Oncology and Immunology Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; 3: Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; 4: Department of Biomedical Sciences, University of Padova, Padova, Italy; 5: Clinical Research Unit, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy; 6: Department of Women’s and Children’s Health, Division of Pediatric Infectious Diseases, University of Padova, Padova, Italy; 7: Clinical and Research Unit of Clinical Immunology and Vaccinology, Bambino Gesu` Children’s Hospital, IRCCS, Roma, Italy

Exploring the extrinsic control of macrophage plasticity in skeletal muscle regeneration

Ombretta Guardiola^1,2, Monica Nicolau³, Angela Gambardella^1,2, Gennaro Andolfi^1,2, Carmela Dell'Aversana^4,5, Lucia Altucci^6,7,8, Chiara Nicoletti³, Gabriella Minchiotti^1,2

1: Stem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR, Naples, 80131, Italy; 2: Institute of Genetics and Biophysics "A. Buzzati-Traverso", CNR, Naples, 80131, Italy; 3: Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA; 4: Department of Medicine and Surgery, LUM University, Casamassima (BA), Italy; 5: Istituto degli Endotipi in Oncologia, Metabolismo e Immunologia "Gaetano Salvatore", CNR Naples, Italy; 6: Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy; 7: BIOGEM, Ariano Irpino, Ariano Irpino, AV, 83031, Italy; 8: Program of Medical Epigenetics, Vanvitelli Hospital, Naples, Italy

Human volatilome insights: biomarkers for chronic kidney disease and associated cognitive decline

Giulia My¹, Angiola Forleo¹, Alessandra Aloisi¹, Maria Teresa Cimmarusti², Marco Fiorentino², Alessandra Stasi², Rossana Franzin², Monica Campioni², Stefania Rotella², Gesualdo Loreto², Simonetta Capone¹

1: Institute for Microelectronics and Microsystems (CNR-IMM), Via Monteroni, Campus Ecotekne, Lecce, Italy, Italy; 2: Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari

Impact of Fall-Risk-Increasing Drugs on accidental falls and injuries among community-dwelling older adults: an Italian case-control study

LARA PERRELLA^1,2, ELENA OLMASTRONI^3,4, SARA MUCHERINO^1,2, VALENTINA ORLANDO^1,2, MANUELA CASULA^3,4, ENRICA MENDITTO^1,2

1: CIRFF, Center of Pharmacoeconomics and Drug Utilization Research, University of Naples Federico II, Naples, Italy; 2: Department of Pharmacy, University of Naples Federico II, Naples, Italy; 3: Epidemiology and Preventive Pharmacology Service (SEFAP), Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy; 4: IRCCS MultiMedica, Sesto San Giovanni (Milan), Italy

Views of Aging and Self-Care among Older Adults with Non-Communicable Diseases

Fabrizio Mezza¹, Daniela Lemmo¹, Maria Francesca Freda¹, Maddalena Illario², Angela Palomba², Antonio Picone², Carlo Ruosi², Guido Iaccarino³

1: Department of Humanistic Studies, University of Naples Federico II, Italy; 2: Department of Public Health, University of Naples Federico II, Italy; 3: Department of Clinical Medicine and Surgery

Electrocardiography-based heart aging: a novel potential index for risk stratification in the general population

Antonietta Pepe^1,2, Augusto Di Castelnuovo², Simona Costanzo^2,3, María Loreto Muñoz Venegas², Teresa Panzera², Chiara Cerletti², Maria Benedetta Donati², Giovanni de Gaetano², Licia Iacoviello^1,2, Alessandro Gialluisi^1,2

1: Department of Medicine and Surgery, LUM University, Casamassima, Italy; 2: Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; 3: EPIMED Research Center, Department of Medicine and Surgery, University of Insubria, Varese, Italy

Is there an effect of autonomic nervous system on the association between epicardial adipose tissue and cognitive function in the elderly?

Laura Petraglia, Martina Valentino, Maria Perrotti, Maria Pia Calligari, Luca Corbia, Carmine Dello Russo, Stefano Maisto, Giuseppe Rengo, Dario Leosco, Grazia Daniela Femminella

Department of Translational Medical Sciences, University of Naples Federico II

Study of Mitochondrial function in cardiac metabolism of HFpEF

Cristina Gatto, Maria Rosaria Rusciano, Albino Carrizzo, Paola Di Pietro, Luigi Schiavo, Daniele Di Napoli, Ivano Esposito, Valentina D'Agostino, Carmine Vecchione, Michele Ciccarelli

University of Salerno, Italy-Department of Medicine,Surgery and Dentistry

Death by Waiting: Treatment Delays, Emergency Department Congestion and Patients' Outcomes

Jan Mazza, Matteo Lippi Bruni, Cristina Ugolini, Rossella Verzulli

Università di Bologna, Italy

Title: Future Thinking exercise on Aging in Place: A Backcasting by Spoke 5 Experts Sub-title : Assumptions, Framework and Criticalities from a Collective Intelligence Experience

Cristina Gagliardi

IRCCS INRCA, Italy

Investigating the Determinants of Welfare Expenditure for Older Adults in Italian Municipalities

Giuliano Resce¹, Nicola Caravaggio¹, Idola Francesca Spanò¹, Giovanni Lamura², Gabriele Morettini²

1: University of Molise, Italy; 2: INRCA

An Actor-Centered Theoretical Tool for Caregiver Policy Analysis: Comparative Evidence from Italian Metropolitan Cities

Giovanni Amerigo Giuliani, Marco Albertini, Federico Toth, Lavinia De santis, Eva Bei

Univeristà di Bologna, Italy

Interprofessional collaboration: the role of primary care physicians and nurses for a successful chronic disease management program

Marta Giachello, Matteo Lippi Bruni, Cristina Ugolini, Rossella Verzulli

University of Bologna, Italy

DNA methylation signature in blood samples from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) study

Mirella Aurora Aceto¹, Elene Kenia², Teresa Serra Cassano^1,3, Francesco Bruno⁴, Paolo Abbondio⁵, Pierluigi Mercatante^1,3, Silvia Fain¹, Ersilia Paparazzo^1,6, Vincenzo Lagani⁷, Francesco De Rango¹, Giuseppe Passarino¹, Alberto Montesanto¹

1: Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.; 2: School of Natural Sciences and Medicine, Ilia State University, Tbilisi, Georgia.; 3: University of Florence, Department of Statistic, Computer Science and Application, DiSIA, Viale Morgagni, 59, 50134, Florence (FI), Italy.; 4: Faculty of Social and Communication Sciences, Universitas Mercatorum, Piazza Mattei 10, Rome, 00186 Italy.; 5: Laboratory of Ancient DNA, Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, 48121 Ravenna, Italy.; 6: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy.; 7: Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal 23952, Saudi Arabia; Institute of Chemical Biology, Ilia State University, Tbilisi 0162, Georgia.

Exploring epigenetic drift in Alzheimer’s disease by next generation methylation array

Teresa Serra Cassano^1,2, Ersilia Paparazzo^1,3, Mirella Aurora Aceto¹, Vincenzo Lagani⁴, Davide Gentilini^5,6, Davide Sacco⁵, Francesco De Rango¹, Francesca Cavalcanti⁷, Raffaele Maletta⁸, Giuseppe Passarino¹, Alberto Montesanto¹

1: Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy; 2: University of Florence, Department of Statistic, Computer Science and Application, DiSIA, Viale Morgagni, 59, 50134, Florence (FI), Italy; 3: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), Cosenza, Italy.; 4: Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal 23952, Saudi Arabia; Institute of Chemical Biology, Ilia State University, Tbilisi 0162, Georgia.; 5: Department of Brain and Behavioral Sciences, Università di Pavia, Pavia, Italy.; 6: Bioinformatics and Statistical Genomics Unit, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Milan, Italy.; 7: Institute for Biomedical Research and Innovation (IRIB), Italian National Research Council (CNR), Mangone, Italy.; 8: Regional Neurogenetic Centre (CRN), Department of Primary Care, Azienda Sanitaria Provinciale Di Catanzaro, Lamezia Terme, CZ, Italy.

Strategies to study the biology of aging before Alzheimer's disease onset

Lorenzo Neri, Alessia Vignoli, Marina Bacci, Alessandra Bigi, Benedetta Mannini, Andrea Morandi, Leonardo Tenori, Fabrizio Chiti

Università degli Studi di Firenze, Italy

Exploring the influence of multiple exposome layers on Alzheimer’s Disease risk: findings from the Moli-sani cohort

Antonietta Pepe^1,2, María Loreto Muñoz Venegas², Federica Santonastaso³, Simona Costanzo^2,4, Maria Ilenia De Bartolo^5,6, Americo Bonanni², Augusto Di Castelnuovo², Alfonso Di Costanzo⁷, Nicola Pirastu³, Matteo Renzi⁸, Giovanni Veronesi⁴, Gaetano Zazzaro⁹, Francesco Gianfagna⁴, Alfredo Berardelli^5,10, Maria Benedetta Donati², Giovanni de Gaetano², Nicole Soranzo^3,11,12, Licia Iacoviello^1,2, Alessandro Gialluisi^1,2

1: Department of Medicine and Surgery, LUM University, Casamassima, Italy; 2: Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; 3: Human Technopole, Milan, Italy; 4: EPIMED Research Centre, Department of Medicine and Surgery, University of Insubria, Varese, Italy; 5: IRCCS NEUROMED, Pozzilli, Italy; 6: Department of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza University of Rome, Rome, Italy; 7: Centre for Research and Training in Medicine of Aging, Department of Medicine and Health Science "V. Tiberio," University of Molise, Campobasso, Italy; 8: Department of Epidemiology, Lazio Region Health Service/ASL Roma 1, Rome, Italy; 9: CIRA-Italian Aerospace Research Centre, Capua, Italy; 10: Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy; 11: British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; 12: Human Genetics Department, Wellcome Sanger Institute (WT), Hinxton, UK

The performance of a plasma biomarker panel in detecting cognitive decline in Alzheimer's disease and its preclinical stages.

Assunta Ingannato^1,2, Silvia Bagnoli^1,2, Katia Maria Giametta¹, Elisa Marcantelli¹, Giulia Giacomucci¹, Chiara Crucitti¹, Valentina Bessi¹, Sandro Sorbi^1,2, Benedetta Nacmias^1,2

1: Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; 2: IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy

Stable non-cohabiting relationships (Living Apart Together) and male sexual health: results from the EMAS population

Clotilde Sparano¹, Giammarco Alderotti², Giovanni Corona³, Giulia Rastrelli⁴, Linda Vignozzi⁴, Daniele Vignoli², Mario Maggi¹, EMAS group⁵

1: SODc Endocrinologia, Dipartimento di Scienze Biomediche, Sperimentali e Cliniche “Mario Serio”, Università degli Studi di Firenze, Firenze, Italia; 2: Department of Statistics, Computer Science, Applications, University of Florence, Florence, Italy; 3: Endocrinology Unit, Azienda USL Bologna, Bologna, Italy; 4: Andrology, Women’s Endocrinology and Gender Incongruence Unit, "Mario Serio", Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy; 5: EMAS group

Fertility intentions of migrants in Italy: searching for sources of variation between men and women and across origins

THAIS GARCIA PEREIRO¹, GIUSEPPE GABRIELLI², ANNA PATERNO¹, SALVATORE STROZZA²

1: Università degli Studi di Bari Aldo Moro; 2: Università degli Studi di Napoli Federico II

The Impact of Spousal Loss on Life Satisfaction: Evidence from SHARE.

Lucia Zanotto, Chiara Ludovica Comolli, Roberto Impicciatore

University of Bologna, Italy

Re-partnering in mid- and later life in Italy

Revathi Palat Rao¹, Elena Pirani²

1: University of Florence, Italy, Italy; 2: University of Florence, Italy, Italy

Health and Union Dissolution After Midlife: A Dyadic Approach

Giammarco Alderotti, Daniele Vignoli, Carlos Gil

University of Florence, Italy

Pronatalist vs. Structural Approaches to Addressing Low Fertility: Lessons from the Italian Case

Raffaele Guetto, Daniele Vignoli

University of Florence, Italy

The Contribution of Medically Assisted Reproduction to Fertility in Italy

Alessandra Burgio¹, Cinzia Castagnaro¹, Gustavo De Santis², Daniele Vignoli², Agnese Vitali³

1: Istat, Italy; 2: University of Florence, Italy; 3: University of Trento, Italy

Women reproductive health in ageing society and private pubblic intervention

Sara Landini, Simona Viciani, Giulia Biagioni, Emilia Giusti

Unifi, Italy

The meaning of Ageing: Perspectives from Ageing Migrants Caregivers in Italy

Lucrezia Alice Moschetta

Università di Padova, Italy

Supporting unpaid carers of older people in Italy: an analysis of the implementation of international policy recommendations at regional level

Giovanni Lamura, Cristina Calvi, Georgia Casanova, Federico Sofritti

INRCA IRCCS, Italy

Home Caregivers and Intersectional Discrimination: The Dark Side of the Care Sector

Maria Teresa Ambrosio, Luisa Corazza

Università degli Studi del Molise, Italy

Living (and Caring) Longer? Changes in Informal Care Provision Across Life in Italy

Cecilia Tomassini¹, Elisa Cisotto², Eleonora Meli³

1: Department of Economics, University of Molise, Italy; 2: Department of Statistics, Università Cattolica del Sacro Cuore, Milan, Italy; 3: ISTAT- Italian National Institute of Statistics, Italy

Feasibility and acceptability of Wearable Sensors and Online Questionnaires in Family Caregivers of People with Dementia: Preliminary Evidence from the ICare.IT – AvereCura Study

Ylenia Druda¹, Angela Berardi¹, Paola Di Florio¹, Marcello Sicbaldi¹, Francesco Palmese¹, M. Gabriella Melchiorre², Marco Socci², Serena Cancellieri², Mascia Tacconi³, Jessica Babini³, Francesca Zanasi¹, Eva Bei¹, Ilaria Chirico¹, Sara Trolese¹, Emma Capulli¹, Francesca Ingravallo¹, Rabih Chattat¹, Marco Albertini¹, Alessandro Silvani¹, Marco Domenicali¹

1: Università di Bologna - Alma Mater Studiorum, Italy; 2: National Institute of Health and Science on Ageing (INRCA), Italy; 3: Center for Cognitive Disorders and Dementias, Ausl Romagna, Italy

La figura del caregiver e la tutela della persona anziana. Questioni giuridiche trasversali

Stefano Corso, Arianna Fusaro, Giovanni Calabrese, Michela Lucchiari, Matilde Girolami, Mariassunta Piccinni

Università degli studi di Padova, Italy

Population ageing in Italy: household dynamics, care needs and labour participation

Fabrizio Culotta

University of Milan-Bicocca, Italy

Age-It Scholar: A Free Knowledge Hub on Ageing and Society

Mario Mezzanzanica

University of Milano - Bicocca

GDPR compliance and the use of microdata in AGE-IT research- Challenges and Possible Solutions

Matteo De Pamphilis¹, Giovanna Boccuzzo²

1: Ca' Foscari University Venice; 2: University of Padova, Italy

The new data sets created in Age-It: results from an online Survey

Agar Brugiavini

Ca' Foscari University of Venice, Italy

Metabolic profiling of MASLD patients identifies age-dependent and age-independent metabolic markers of liver fibrosis.

Tania D'Amico¹, Simone Giannini¹, Simone Di Cola¹, Annamaria Sabetta¹, Francesca Maiorca¹, Marin Pecani¹, Marzia Miglionico², Giulio Francesco Romiti¹, Serena Zampieri³, Greta Petrella³, Daniel Oscar Cicero³, Stefania Basili¹, Valeria Raparelli¹

1: Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; 2: Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy; 3: Department of Chemical Science and Technology, University of Rome "Tor Vergata," Rome, Italy

MAPK15 controls intracellular lipid uptake and protects mammalian liver from steatotic disease

Giovanni Inzalaco^1,2, Sara Gargiulo¹, Denise Bonente³, Lisa Gherardini¹, Lorenzo Franci^1,2, Federico Galvagni⁴, Virginia Barone³, Mario Chiariello^1,2

1: Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Siena, Italy; 2: Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica, Siena, Italy; 3: Department of Life Sciences, University of Siena University, Italy; 4: Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy

Linking Mitochondrial DNA Damage to Vascular Aging and Premature Coronary Artery Disease: Evidence from Clinical and Cellular Models

Paola Canale^1,3, Jonica Campolo², Lisa Alibrandi¹, Alessia Cuccaro¹, Francesca Scebba¹, Francesca Forini³, Giuseppina Nicolini³, Marina Parolini², Gianluca Gazzaniga⁴, Emanuela Piccaluga⁵, Irene Marinaro³, Antonella Mercuri³, Stefano Turchi³, Maria Grazia Andreassi³

1: Health Science Interdisciplinary Center, Sant'Anna School of Advanced Studies, Pisa, Italy; 2: CNR Institute of Clinical Physiology, Milan, Italy; 3: CNR Institute of Clinical Physiology, Pisa, Italy; 4: Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Rome, Roma, Italy; 5: Interventional Cardiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

Trace Metal Imbalance and Anemia Prevalence in Older Adults with Impaired Kidney Function: Evidence from NHANES

Guido Gembillo¹, Luca Soraci², Andrea Corsonello², Domenico Santoro¹

1: Unit of Nephrology and Dialysis, University of Messina, Italy.; 2: Unit of Geriatric Medicine, Italian National Research Center on Aging (IRCCS INRCA), 87100 Cosenza, Italy.

Translating Science into Impact: Tackling Biological Ageing Through Innovation

Sofia Pavanello¹, Manuela Campisi², Luana Cannellla³

1: AZIENDA OSPEDALE UNIVERSITA' DI PADOVA, Italy; 2: AZIENDA OSPEDALE UNIVERSITA' DI PADOVA, Italy; 3: AZIENDA OSPEDALE UNIVERSITA' DI PADOVA. Italy

GDF-15, FGF21, sRAGE, and NfL as Biomarkers of Sarcopenia, Malnutrition, and Frailty: Evidence from the Age-It Study

Sarah Damanti^1,2, Clara Sciorati¹, Laura Zagato⁷, Lorena Citterio⁷, Edoardo Spinelli^1,3,4, Federica Agosta^1,3,4, Massimo Filippi^1,3,4,5,6, Paolo Manunta^1,7, Chiara Lanzani^1,7, Patrizia Rovere-Querini^1,2

1: Università Vita Salute San Raffaele, Italy; 2: Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 3: Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; 4: Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 5: Neurophysiology Service, IRCCS San Raffaele Scientific Institute, Milan, Italy; 6: Neurorehabilitation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 7: Nephrologic Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy

Searching for (dis-)similarities between the timing of international migration, union formation and acquisition of the Italian citizenship

Anna Paterno¹, Thaís García-Pereiro¹, Laura Terzera²

1: Università degli Studi di Bari Aldo Moro; 2: Università degli Studi di Milano-Bicocca

The Integration Paths of Eastern European Women in Italy: New Arrivals, Marriages, and Acquisitions of Citizenship

Cinzia Conti¹, Antonella Guarneri¹, Fabio Massimo Rottino¹, Salvatore Strozza²

1: Istat, Italy; 2: Università degli Studi di Napoli Federico II

Migrants' Socio-Economic Integration: The Case of Italy - Preliminary analysis

Roberta Defazio^1,2, Thaís García - Pereiro², Anna Paterno²

1: Università di Firenze & Università degli studi di Bari, Italy; 2: Università degli studi di Bari, Italy

Beyond Labour Integration: Migrant Women and Citizenship in an Ageing Italy

Rosa Gatti

Università degli Studi di Napoli Federico II, Italy

Assessing the Redistributive Aspects of the Italian Pension System

Koray Aktas, Danilo Cavapozzi, Monica Paiella

Ca' Foscari University of Venice, Italy

Measuring pension fragility

Koray Aktas¹, Danilo Cavapozzi¹, Monica Paiella²

1: Ca' Foscari University of Venice, Italy; 2: University of Naples "Parthenope", INPS

Occupation-specific health hazards and trajectories to retirement

Danilo Cavapozzi, Ya Gao, Irene Mammi

Ca' Foscari University of Venice, Italy

The implicit pension debt in pay-as-you-go pension systems: the stationary and balanced case

Gustavo De Santis

University of Firenze, Italy

Age-related trends of serum Neurofilament light chain in hospitalized and home-dwelling cohorts and prognostic relevance for mortality

Giulia Matacchione¹, Francesca Marchegiani¹, Francesco Piacenza², Mirko Di Rosa³, Matilde Sbriscia², Chiara Giordano¹, Sonia Fantone², Rina Recchioni¹, Nicola Montano⁴, Evelyn Ferri⁵, Stefano Salvioli^6,10, Maria Conte⁶, Beatrice Arosio^4,5, Antonio Domenico Procopio¹, Anna Rita Bonfigli⁷, Jacopo Sabbatinelli^1,9, Antonio Cherubini^8,9, Fabrizia Lattanzio⁷, Fabiola Olivieri^2,9

1: Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy; 2: Advanced Technology Center for Aging Research and Geriatric Mouse Clinic, IRCCS INRCA, Ancona, Italy; 3: . Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 4: Department of Clinical Sciences and Community Health, University of Milan, Miano,Italy; 5: Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico,Milano,Italy; 6: Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; 7: Scientific Direction, IRCCS INRCA, Ancona, Italy; 8: Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy; 9: . Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; 10: IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy

Detecting amyloid and tau pathology in Parkinson disease, 4R-tauopathies and control subjects with plasma ptau217

Eleonora Fiorenzato¹, Giulia Musso², Valentina Misenti¹, Simone Cauzzo¹, Roberta Biundo^3,4, Carmelo Fogliano¹, Giulia Bonato^1,5, Wassilios G. Meissner^6,7, Marta Campagnolo¹, Miryam Carecchio¹, Francesca Vianello³, Andrea Guerra¹, Chiara Cosma², Annachiara Cagnin^5,8, Diego Cecchin^5,9, Martina Montagnana², Angelo Antonini^1,5

1: Parkinson and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE), Department of Neuroscience, University of Padova, via Giustiniani 2, 35121 Padua, Italy; 2: Department of Medicine – DIMED, University of Padova, via Giustiniani 2, 35121 Padua, Italy; 3: Complex Operative Unit (UOC) of the Psychology, Neurology Hospital division, Padova University Hospital, via Giustiniani 2, 35121 Padua, Italy; 4: Department of General Psychology, University of Padova, via Venezia 8, 35131 Padua, Italy; 5: Padova Neuroscience Center (PNC), University of Padova, via Orus 2b, 35131 Padua, Italy; 6: CHU Bordeaux, Service de Neurologie des Maladies Neurodégénératives, IMNc, Place Amélie Raba-Léon, 33000 Bordeaux, France; 7: Univ. de Bordeaux, CNRS, IMN, UMR 5293, 146 rue Léo Saignat, 33000 Bordeaux, France; 8: Department of Neuroscience, University of Padova, via Giustiniani 2, 35121 Padua, Italy; 9: Nuclear Medicine Unit, Department of Medicine (DIMED), University of Padova, via Giustiniani 2, 35121 Padua, Italy

Innovating Brain Health: An Italian Experience with a Community-Based Service

Edoardo Gioele Spinelli^1,2, Elisa Canu², Elisa Sibilla², Bianca Lamorgese¹, Giordano Cecchetti², Veronica Castelnovo², Giulia Rugarli^1,2, Alma Ghirelli^1,2, Roberto Santangelo², Jacopo Lanzone², Marco Cursi², Luca Zanchi², Federica Agosta^1,2, Massimo Filippi^1,2

1: Vita-Salute San Raffaele University, Italy; 2: IRCCS Ospedale San Raffaele

Shp1 Modulates Apoptosis and Senescence Pathways in Retinal Cells: Implications for Age-Related Macular Degeneration

Sabrina Gargiulo, Antonino Colanzi, Daniela Corda, Alessia Varone

Institute of Endotypes in Oncology, Metabolism, and Immunology “G. Salvatore”, National Research Council, Naples, Italy

The Cost of Loss: Unequal Bereavement effects in Later Life

Chiara Ludovica Comolli¹, Diego Pieroni², Valentina Ricci²

1: Università di Bologna, Italy; 2: INPS

New insights into fertility intentions and realizations through a longitudinal register of individuals in Italy

Cinzia Castagnaro¹, Eleonora Meli¹, Daniele Vignoli², Letizia Mencarini³

1: Istat, Italy; 2: University of Florence; 3: Bocconi University

Work-family trajectories and health: the role of partners’ crossover effects

Davide Gritti, Raffaele Grotti, Stefani Scherer

Trento University, Italy

Income and Fertility in Couples: New Evidence from Longitudinal Tax Data in Tuscany

Carlos J. Gil-Hernández¹, Daniele Vignoli¹, Raffaele Guetto¹, Marialuisa Maitino², Letizia Ravagli²

1: University of Florence, Department of Statistics, Computer Science, Applications, Italy; 2: Istituto Regionale per la Programmazione Economica della Toscana (IRPET), Italy

Modern Family: Transition to Single Parenthood and the Consequences for Well-Being

Andrea Ballerini, Raffaele Guetto

University of Florence, Italy

Attitudes towards ART: a vignette study

Daniele Vignoli¹, Valentina Tocchioni², Marco Cozzani³, Ester Lazzari⁴

1: Università degli Studi di Firenze, Italy; 2: Università degli Studi di Firenze, Italy; 3: Università degli Studi di Firenze, Italy; 4: Vienna Institute of Demography

Silver surfers' social ties: understanding social network usage among Italian seniors

Margherita Silan, Giorgia Bernardinis, Sophie Grace Parolin

University of Padova, Italy

Older LGBTQ+ Adults and Affirmative Sports Environments: Indicators and Best Practices

Chiara Antoniucci¹, Roberto Baiocco¹, Jessica Pistella¹, Guido Alessandri², Fabio Alivernini¹, Anna Maria Borghi³, Andrea Chirico¹, James Dawe⁴, Lorenzo Filosa², Chiara Fini³, Tommaso Palombi³, Simone Tavolucci², Fabio Lucidi¹

1: Department of Social and Developmental Psychology, Sapienza University of Rome, Italy; 2: 2 Department of Psychology, Sapienza University of Rome, Italy; 3: Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Italy; 4: Department of Humanities and Social Sciences, Universitas Mercatorum Telematic University, Italy

Matching care needs of LGBTQAI+ older adults and care workers’ education: a systematic review of reviews

Rebecca Graziosi, Georgia Casanova, Giovanni Lamura

INRCA, Italy

Improving Elderly Quality of Life through Innovative Social Day Care Centres. A Case Study in Rome within the Age-It Programme

Maria Argenti, Fabio Cutroni, Domizia Mandolesi, Anna Bruna Menghini, Maura Percoco, Francesca Sarno

Sapienza University of Rome, Italy

Sex-specific network dynamics of multimorbidity

Erika Banzato, Giovanna Boccuzzo

Department of Statistical Sciences, University of Padova, Padova, Italy

Forgotten in the hospital: The Effect of Municipality Social Spending on Elderly Hospital-related Outcomes.

Giovanni Fattore, Simone Ghislandi, Irene Torrini

Department of Social and Political Sciences, Bocconi University, Italy

PrivGen: A Human-in-the-Loop Approach to Generate Private Synthetic Data

Navid Nobani¹, Giovanni Officioso¹, Mario Mezzanzanica¹, Giancarlo Sperlì², Fabio Mercorio¹

1: University of Milan-Bicocca, Italy; 2: University of Naples Federico II, Naples, Italy

A Thematic Data Platform for Research on Ageing

Mario Mezzanzanica, Fabio Mercorio, Navid Nobani, Anna Velyka, Filippo Pallucchini

University of Milan-Bicocca, Italy

Bridging Data for Better Ageing: Advancing Measurement of Healthy Ageing in Italy

Andreea Alexandra Piriu, Aleksandra Torbica

Bocconi University, Italy

Development of a Parallel, Multi-Wavelength, Multi-Channel, Multi-Distance, Time-Resolved Near Infrared Spectrometer

Scott Pesenti¹, Alessandro Torricelli^1,2, Lorenzo Spinelli¹

1: Consiglio Nazionale delle Ricerche, Italy; 2: Dipartimento di Fisica, Politecnico di Milano

Experimental analysis and physics-based analytical model on Twisted and Coiled Artificial Muscles (TCAMs): innovative smart actuators for rehabilitation robotics

Salvatore Garofalo, Chiara Morano, Leonardo Pagnotta, Luigi Bruno

Department of Mechanical, Energy and Management Engineering, University of Calabria, Rende, Italy

COG-BCI: an adaptive EEG-based Brain Computer Interface for COGnitive training in elderly people

Emma Colamarino^1,2, Elena Mongiardini¹, Febo Cincotti^1,2

1: Sapienza University of Rome, Italy; 2: Fondazione Santa Lucia IRCCS, Rome, Italy

Biomechanical Assessment of Exo-Assistance

Raffaella Mancino¹, Aldo Smaldone², Mariarosaria Meola², Raffaele Dubbioso², Giovanni Berselli¹, Fanny Ficuciello²

1: Università di Genova, Italy; 2: Università degli studi di Napoli Federico II

On the development of a novel Virtual Sensing methodology for indirect sensing of muscle forces during robotic rehabilitation and motion assistance

Michele Perrelli, Rocco Adduci, Francesca Alvaro, Domenico Mundo

University of Calabria, Italy - Department of Mechanical, Energy, and Management Engineering

VITAL SIGNAL MEASUREMENTS AND FEATURES EXTRACTIONS FROM A LOW-COST DEVICE IN AGEING

Livio D'Alvia¹, Chiara Bencivenga¹, Roberto Cangemi², Stefania Basili², Zaccaria Del Prete¹

1: DIMA, Sapienza University of Rome, Via Eudossiana 18 – 00100, Rome; 2: DMTP, Sapienza University of Rome, Viale del Policlinico, 155 - 00185 - Roma

Territorial Disparities and School Dropouts in Italian High Schools

Salvatore Battaglia, Naomi Failla, Umberto De Simone, Massimo Attanasio

University of Palermo, Italy

Neurophysiological markers of human-exoskeleton integration

Margherita Bertuccelli^1,2, Stefano Tortora^1,2, Mariasole Pasinato¹, Edoardo Trombin¹, Alfonc Baba^2,3, Patrizia Bisiacchi⁴, Giovanni Sparacino¹, Emanuele Menegratti^1,2, Alessandra Del Felice^2,3

1: Department of Information Engineering, Università degli studi di Padova, Italy; 2: Padova Neuroscience Center, Università degli studi di Padova; 3: Department of Neuroscience, Università degli studi di Padova; 4: Department of General Psychology, Università degli studi di Padova

Novel biomarkers for the diagnosis of cognitive decline in patients with chronic kidney disease

Maria Teresa Cimmarusti, Alessandra Stasi, Marco Fiorentino, Rossana Franzin, Monica Campioni, Sabrina Carparelli, Paola Pontrelli, Loreto Gesualdo

University of Bari, Italy

Polypharmacy and Orthostatic Hypotension in Hospitalized Older Patients: A Cross-Sectional Analysis

Laura Andreea Ceparano, Laura de Lisio, Chiara Di Lorenzo, Alessandro Caracciolo, Giovanni Curcio, Lucia De Maria, Gambino Giuseppina, Maria Grazia Landi, Pasquale Pezzella, Ivana Serino, Annachiara Vassallo, Valeria Zanobbi, Grazia Daniela Femminella, Nicola Ferrara, Giuseppe Rengo, Leonardo Bencivenga

Dipartimento di Scienze Mediche Traslazionali, Federico II University, Naples, Italy, Italy

The Role of Cardiopulmonary Exercise Testing in the Evaluation of Patients with Anderson-Fabry Disease

Alessandra Cuomo, Antonio Bianco, Antonella Di Donato, Letizia Spinelli, Eleonora Riccio, Maddalena Illario, Antonio Pisani, Guido Iaccarino

Università degli Studi di Napoli Federico II, Italy

“Ageing? I say yes!”: a Hybrid-AI Approach to develop a web application for sustaining older workers’ work-life balance.

Greta Falavigna¹, Donatella Bramanti², Luisa Errichiello³, Sara Nanelli⁴

1: Research Institute on Sustainable Economic Growth of the National Research Council (CNR-IRCrES)), Italy; 2: Università Cattolica del Sacro Cuore di Milano; 3: Institute for Studies on the Mediterranean of the National Research Council (CNR-ISMed)), Italy; 4: Università Cattolica del Sacro Cuore di Milano

Age-related acidosis as a driver of bone marrow adipose tissue changes in osteoporosis

Jasmine Molaschi¹, Gemma Di Pompo², Sofia Avnet¹, Nicola Baldini^1,2

1: Università degli Studi di Bologna, Italy; 2: IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Aging lung: the association between muscle strength and z scores of pulmonary function in a general population sample

Nicola Ferrara¹, Laura Petraglia¹, Leonardo Bencivenga¹, Giuseppe Rengo¹, Raffaella Pagliaro², Angela Sciattarella², Andrea Bianco², Germano Guerra³, Klara Komici³

1: University of Naples "Federico II", Italy; 2: University of Campania "L. Vanvitelli," Naples, Italy.; 3: University of Molise, Campobasso, Italy

Cognitive performance and gait analysis in cognitively unimpaired adults. Preliminary findings from the “Instrumental Pattern of Cognitive Decline: a data-driven approach. The DataCOG Study”.

Federico Mollame¹, Alice Tomaselli¹, Andrea Caruso², Massimiliano Salfi², Caterina Gagliano¹, Francesco Cappellani¹, Antonino Maniaci¹, Emilia Gallo¹, Francesco Pegreffi¹, Salvatore Lavalle¹, Roberta Torrisi², Antonina Luca¹

1: University of Enna Kore, Italy; 2: vEyes ONLUS

Customizable Hybrid Exo-Prosthesis System

Marcella Piacentino, Mariarosaria Meola, Fanny Ficuciello

Università degli Studi di Napoli 'Federico II', Italy

Demographic dynamics and the labor market

Valeria Allocca

Università degli Studi di Napoli Federico II, Italy

Demographic trends and investment strategies: How longevity shapes pension funds' equity exposure

Rosa Cocozza, Domenico Curcio, Serena Gallo

University of Naples Federico II, Italy

Development and Validation of Shape Memory Alloy-Based Actuators for Rehabilitative Exoskeletons

Stefano Rodinò¹, Carmine Maletta²

1: UNICAL, Italy; 2: 2SMArtest

Diritto del lavoro e persona anziana: il c.d. Age Management nel contesto aziendale

Michela Lucchiari, Arianna Fusaro, Giovanni Calabrese, Stefano Corso, Mariassunta Piccinni, Matilde Girolami

Università degli Studi di Padova, Italy

Impaired cAMP/PKA/CREB1 signaling drives mitochondrial dysfunction in skeletal muscle wasting

Elia Angelino^1,2, Lorenza Bodo², Suvham Barua^1,2, beatrice D'Anna², Alessia Meschi², Carolina Sciavolino², Andrea Graziani^1,2

1: Università del Piemonte Orientale, Dept. of Translational Medicine, Italy; 2: Università di Torino, Molecular Biotechnology Center, Department of Molecular Biotechnology and Healths Sciences

Irisin correlates with disease biomarkers and cognitive function in Alzheimer disease.

Manuela Dicarlo¹, Patrizia Pignataro², Daniele Urso³, Chiara Zecca³, Roberta Zerlotin¹, Graziana Colaianni¹, Angela Oranger¹, Clelia Suriano², Silvia Colucci², Giancarlo Logroscino³, Maria Grano¹

1: University of Bari "Aldo Moro",Department of Precision and Regenerative Medicine and Ionian Area,Italy; 2: University of Bari "Aldo Moro", Department of Translational Biomedicine and Neuroscience, Italy; 3: Center for Neurodegenerative Diseases and the Aging Brain, University of Bari “A. Moro” at “Pia Fondazione Card G. Panico” Hospital, Italy.

Loneliness in caregivers of patients with cognitive decline

Rita Pezzella, Chiara De Salvo, Gianluca Scotto di Tella, Vittoria Canzanella, Maddalena Vasto, Sara Rinaldi Landolina, Carmine Dello Russo, Maria Perrotti, Luca Corbia, Valeria Accardo, Dario Leosco, Giuseppe Rengo, Laura Petraglia, Grazia Daniela Femminella

University of Naples Federico II, Italy

Low-grade inflammation, platelet reactivity and mitochondrial function in individuals with permanent atrial fibrillation.

Francesco Vollero, Giovanni Buoninfante, Valeria Trapani, Angela Pia Speziale, Annamaria Sabetta, Francesca Maiorca, Valeria Raparelli, Stefania Basili, Giulio Francesco Romiti, Lucia Stefanini

Department of Translational and Precision Medicine, Sapienza University of Rome, Italy.

Multimodal Instrumentation for Thermodynamic Data Collection and Validation in Aerobic Exercise across age-spectrum Through Infrared Thermography

Aiman Rashid, Assal Selma, Matteo Cammarata, Daniele Fiaschi

Università degli Studi di Firenze, Italy

National Recovery and Resilience Plan (NRRP) Cascade Funding - Age-it. CODIGE Project: Comorbidity and Iatrogenic Damage in Geriatric Oncology. Objectives, Methodologies, Study population and Expected results

Amelia Filippelli¹, Anna Citarella², Simona Cammarota², Federica Papaccio¹, Elena Ciaglia¹, Federica Campana¹, Emanuela De Bellis¹, Nicola Ferrara³, Valeria Conti¹

1: Department of Medicine Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, Baronissi, Italy; 2: LinkHealth - Health economics, Outcomes & Epidemiology srl, Naples, Italy; 3: Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.

Nutritional Status and Sympathovagal Imbalance in Elderly Patients

Maria Perrotti, Mariapia Calligari, Martina Valentino, Luca Corbia, Carmine Dello Russo, Stefano Maisto, Dario Leosco, Giuseppe Rengo, Grazia Daniela Femminella, Laura Petraglia

Department of Translational Medical Science, University of Naples “Federico II”

Outcome measures for health interventions targeting multimorbid older adults: A systematic review.

Massimiliano Fedecostante¹, Alessia Beccacece¹, Paolo Balietti¹, Barbara Carrieri¹, Massimiliano Orso¹, Alessandra Coin², Chiara Ceolin², Giuseppe Sergi², Francesca Cecchi³, Marco Baccini³, Diego Longo³, Rosa Liperoti^4,5, Fabrizia Lattanzio¹, Antonio Cherubini¹

1: IRCCS INRCA, Ancona, Italy; 2: University of Padua, Padua, Italy; 3: University of Florence, Florence, Italy; 4: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; 5: Università Cattolica del Sacro Cuore, Milan, Italy.

Recognize the talent. Complexity of the transmission of "know-how" between generations in the Veneto craftsmanship

Fabio Gasparini

Consiglio Nazionale Ricerche (IRPPS), Italy

Reducing vulnerability to online misinformation among older adults: a literature review

Cristina Meini¹, Erica Viola², Caristia Silvia³

1: University of Eastern Piedmont, Italy; 2: University of Eastern Piedmont, Italy; 3: University of Eastern Piedmont, Italy

SGLT2 inhibitors and cognitive decline: a systematic review and meta-analysis

Chiara Di Lorenzo¹, Laura Andrea Ceparano¹, Laura de Lisio¹, Grazia Daniela Femminella¹, Nicola Ferrara¹, Leonardo Bencivenga¹, Klara Komici², Giuseppe Rengo¹

1: Università degli Studi di Napoli Federico II, Italy; 2: Università degli Studi del Molise, Italy

The Role of Regular Physical Activity in Restoring Immune Balance After Myocardial Infarction in Older Adults

Davide Proietto, Elena Torreggiani, Antonella Caputo, Riccardo Gavioli, Simona Mandini, Elisabetta Tonet, Beatrice Dallan, Enrico Tassani, Mara Martino, Tommaso Piva, Valentina Zerbini, Andrea Raisi, Gianluca Campo, Giovanni Grazzi, Francesco Nicoli

University of Ferrara, Italy

The Role of Rehabilitation in Preventing Falls in the Elderly: Presentation of the Pilot Study

ANTONIO PICONE, PALOMBA ANGELA, LEMMO DANIELA, MEZZA FABRIZIO, FREDA FRANCESCA, RUOSI CARLO

University of Naples Federico II, 80131 Naples, Italy, Italy

Total factor productivity and health for ageing workers in the Italian regions

Emanuela Resta

University Sapienza of Rome, Italy

Unravelling the link between uromodulin dosage, aging and risk of chronic kidney disease

Sofia Bindelli¹, Mariapia Giuditta Cratere¹, Claudia Tammaro¹, Lara Davani², Alessandra Altomare², Céline Schaeffer¹, Luca Rampoldi¹

1: Molecular Genetics of Renal Disorders, Division of Genetics and Cell Biology, University Vita-Salute San Raffaele, Milan; 2: Department of Pharmaceutical Analysis, University of Milan

Re-Starting! How women over 50 learn to teach?

Anna D'Ascenzio

CNR, Italy

From migration to familiarisation. Family profiles, family-making processes and policy challenges in Italy

Stefano Montrasio, Laura Terzera

Università degli Studi di Milano-Bicocca, Italy

Radiomics and Machine Learning for Breast Density Classification in elderly patients from MRI

Corrado Caiazzo, Francesco Mercaldo, Giulia Varriano, Dalila De Lucia, Maria Chiara Brunese, Simona Correra, Antonella Santone

Università degli Studi del Molise, Italy

Replacement Migration: Respect and Harms

Davide Pala¹, Gloria Zuccarelli²

1: Università Piemonte Orientale, Italy; 2: Università Piemonte Orientale, Italy

Active waiting spaces in primary care territorial facilities to promote healthy ageing

Elena Bellini, Nicoletta Setola

University of Florence, Department of Architecture, TESIS center, Italy

Beyond the Skin: Integrating mHealth and Multidisciplinary Care in Hidradenitis Suppurativa Management

Annachiara Cavaliere

Università degli Studi di Napoli Federico II, Italy

Innovative intervention supported by digital technologies for healthy and active ageing: Innovative approach to the subject with hypogonadism.

Francesco Garifalos, Davide Menafra, Cristina de Angelis, Angelica Larocca, Michele Virgolesi, Sara Aprano, Vincenzo De Luca, Erminia Attaianese, Mariangela Perillo, Daniela Lemmo, Maria Francesca Freda, Guido Iaccarino, Maddalena Illario, Annamari Colao, Rosario Pivonello

Università degli Studi di Napoli Federico II, Italy

Role Of Mitochondrial Dysfunction In The Pathogenesis Of Fabry Cadriomiopathy

Jessica Gambardella, Antonella Fiordelisi, Federica Andrea Cerasuolo, Antonietta Buonaiuto, Roberta Avvisato, Alessandra Cuomo, Antonio Bianco, Eleonora Riccio, Antonio Pisani, Daniela Sorriento, Guido Iaccarino

Università degli Studi di Napoli Federico II, Italy

The Role of Nursing in Promoting Health for Aging Populations: A scoping review

Michele Virgolesi

Università Federico II di Napoli, Italy

Trapped by Age and Gender: Exploring the Combined Effects of Ageism and Sexism in Organizational Settings

Alessia Valmori, Claudia Manzi

Catholic University of the Sacred Heart - Milan, Italy

Brief online vocal interactions influence closeness and sensorimotor-interoceptive activation in an age-dependent manner

Chiara Fini, Vanessa Era, Giovanna Cuomo, Ilenia Falcinelli, Anna M, Borghi

Sapienza, University of Rome, Italy

Thinking Climate Change through the Lens of Abstractness: A Multi-Task and Multi-Setting Investigation into Generational Differences in the Conceptualization of Ecology

Ilenia Falcinelli¹, Chiara Fini¹, Claudia Mazzuca¹, Ludovica Gargiuli¹, Guido Alessandri¹, Fabio Alivernini¹, Roberto Baiocco¹, Andrea Chirico¹, Lorenzo Filosa¹, Tommaso Palombi¹, Jessica Pistella¹, Simone Tavolucci¹, Fabio Lucidi¹, Anna M. Borghi^1,2

1: Sapienza University of Rome, Italy; 2: ISTC-CNR, Rome

Combined Analysis of Alu and ALR Repeats in cfDNA: Potential Prognostic Biomarkers in Geriatric Patients with Cardiovascular Disease

Rosanna Maniscalco¹, Stefania Fumarola¹, Francesca Marchegiani², Emanuele Francini², Alessandro Petrini¹, Anna Rita Bonfigli³, Roberta Galeazzi², Jacopo Sabbatinelli^2,4, Antonio Domenico Procopio^2,4, Mirko Di Rosa⁵, Pierpalo Stripoli², Roberto Antonicelli⁶, Rina Recchioni², Antonio Cherubini^4,7, Fabrizia Lattanzio³, Fabiola Olivieri^1,4, Maurizio Cardelli¹

1: Advanced Technology Center for Aging Research, IRCCS INRCA, Ancona, Italy; 2: Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy; 3: Scientific Direction, IRCCS INRCA, Ancona, Italy; 4: Department of Clinical and Molecular Sciences (DISCLIMO), Università Politecnica delle Marche, Ancona, Italy; 5: Centre for Biostatistics and Applied Geriatric Clinical Epidemiology, IRCCS INRCA, Ancona, Italy; 6: Cardiology Unit, IRCCS INRCA, 60129 Ancona, Italy; 7: Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona,

Cellular senescence in painful neuropathies: characterization of the senescent phenotype

Chiara Sasia, Giacomina Videtta, Nicoletta Galeotti

University of Florence, Italy